Lipocalin 2 from macrophages stimulated by tumor cell-derived sphingosine-1-phosphate promotes lymphangiogenesis and tumor metastasis

Science Signaling

Volumn 9, Issue 434, 2016, Pages

  Jung, Michaela ^a   Ören, Bilge ^a   Mora, Javier ^a,b   Mertens, Christina ^a   Dziumbla, Sarah ^a   Popp, Rüdiger ^a   Weigert, Andreas ^a   Grossmann, Nina ^a   Fleming, Ingrid ^a   Brüne, Bernhard ^a  

^a GOETHE UNIVERSITY   (Germany)

^b UNIVERSIDAD DE COSTA RICA   (Costa Rica)

Author keywords

[No Author keywords available]

Indexed keywords

CD31 ANTIGEN; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; PHOSPHATIDYLINOSITOL 3 KINASE; SPHINGOSINE 1 PHOSPHATE; STAT3 PROTEIN; LCN2 PROTEIN, HUMAN; LCN2 PROTEIN, MOUSE; LYSOPHOSPHOLIPID; SPHINGOSINE; SPHINGOSINE 1-PHOSPHATE; TUMOR PROTEIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; GENE DELETION; GENE EXPRESSION; HUMAN; HUMAN CELL; LYMPHANGIOGENESIS; MACROPHAGE CULTURE; METASTASIS; MOUSE; NONHUMAN; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; REPORTER GENE; TUMOR ASSOCIATED LEUKOCYTE; TUMOR GROWTH; TUMOR MICROENVIRONMENT; TUMOR VASCULARIZATION; WILD TYPE; ANALOGS AND DERIVATIVES; ANIMAL; BREAST TUMOR; ENDOTHELIUM CELL; EXPERIMENTAL MAMMARY NEOPLASM; GENETICS; MACROPHAGE; MCF-7 CELL LINE; METABOLISM; NEOPLASM; PATHOLOGY; SECRETION (PROCESS);

ANIMALS; BREAST NEOPLASMS; ENDOTHELIAL CELLS; FEMALE; HUMANS; LIPOCALIN-2; LYMPHANGIOGENESIS; LYSOPHOSPHOLIPIDS; MACROPHAGES; MAMMARY NEOPLASMS, EXPERIMENTAL; MCF-7 CELLS; MICE; NEOPLASM METASTASIS; NEOPLASM PROTEINS; NEOPLASMS; SPHINGOSINE;

EID: 84978792096     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.aaf3241     Document Type: Article

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