Angiopoietin-2, an angiogenic regulator, promotes initial growth and survival of breast cancer metastases to the lung through the integrin-linked kinase (ILK)-AKT-B cell lymphoma 2 (Bcl-2) pathway

Journal of Biological Chemistry

Volumn 286, Issue 33, 2011, Pages 29249-29260

  Imanishi, Yorihisa ^a,b,c   Hu, Bo ^a,b   Xiao, Gutian ^a,b   Yao, Xuebiao ^d,e   Cheng, Shi Yuan ^a,b  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c KEIO UNIVERSITY   (Japan)

^d UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^e MOREHOUSE SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN-2; BREAST CANCER; BREAST CANCER CELLS; BREAST TUMOR; CELL APOPTOSIS; CELL RETENTION; CELL SURVIVAL; HUMAN BREAST CANCER; IN-VITRO; INTEGRIN-LINKED KINASE; INTEGRINS; LATE STAGE; ORTHOTOPIC; SURVIVAL AND GROWTH; THERAPEUTIC TARGETS; TUMOR CELLS; TUMOR METASTASIS; UNDERLYING MECHANISM; UP-REGULATION;

ANIMALS; AUTOMATA THEORY; BIOLOGICAL ORGANS; CELL CULTURE; CELL DEATH; ENZYMES; PATHOLOGY; PHOSPHORYLATION; TUMORS;

DISEASES;

ANGIOPOIETIN 2; INTEGRIN LINKED KINASE; PROTEIN AKT1; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN KINASE B BETA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER GROWTH; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; CORRELATIONAL STUDY; DISTANT METASTASIS; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG METASTASIS; METASTASIS POTENTIAL; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; UPREGULATION;

ANGIOPOIETIN-2; ANIMALS; APOPTOSIS; BREAST NEOPLASMS; CELL MOVEMENT; CELL SURVIVAL; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; MICE; MICE, NUDE; NEOPLASM METASTASIS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; UP-REGULATION;

ANIMALIA;

EID: 80051693575     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.235689     Document Type: Article

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