-
1
-
-
78049485263
-
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
-
Ferlay J, Shin HR, Bray F, Forman D, Mathers C and Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010; 127: 2893-2917.
-
(2010)
Int J Cancer
, vol.127
, pp. 2893-2917
-
-
Ferlay, J.1
Shin, H.R.2
Bray, F.3
Forman, D.4
Mathers, C.5
Parkin, D.M.6
-
3
-
-
12744261230
-
Prediction of recurrence after radical surgery for gastric cancer: A scoring system obtained from a prospective multicenter study
-
Marrelli D, De Stefano A, de Manzoni G, Morgagni P, Di Leo A and Roviello F. Prediction of recurrence after radical surgery for gastric cancer: A scoring system obtained from a prospective multicenter study. Ann Surg 2005; 241: 247-255.
-
(2005)
Ann Surg
, vol.241
, pp. 247-255
-
-
Marrelli, D.1
De Stefano, A.2
de Manzoni, G.3
Morgagni, P.4
Di Leo, A.5
Roviello, F.6
-
4
-
-
0000197190
-
Clinicopathologic characteristics and prognostic factors in 10,783 patients with gastric cancer
-
Kim JP, Lee JH, Kim SJ, Yu HJ and Yang HK. Clinicopathologic characteristics and prognostic factors in 10,783 patients with gastric cancer. Gastric Cancer 1998; 1: 125-133.
-
(1998)
Gastric Cancer
, vol.1
, pp. 125-133
-
-
Kim, J.P.1
Lee, J.H.2
Kim, S.J.3
Yu, H.J.4
Yang, H.K.5
-
5
-
-
0026593181
-
Histopathologic characteristics of early stage esophageal carcinoma. A comparative study with gastric carcinoma
-
Goseki N, Koike M and Yoshida M. Histopathologic characteristics of early stage esophageal carcinoma. A comparative study with gastric carcinoma. Cancer 1992; 69: 1088-1093.
-
(1992)
Cancer
, vol.69
, pp. 1088-1093
-
-
Goseki, N.1
Koike, M.2
Yoshida, M.3
-
6
-
-
63249092765
-
Persistently-activated Stat3 maintains NF-κB constitutive activity in tumors
-
Lee H, Herrmann A, Deng JH, Kujawski M, Niu G, Li Z, Forman S, Jove R, Pardoll DM and Yu H. Persistently-activated Stat3 maintains NF-κB constitutive activity in tumors. Cancer Cell 2009; 15: 283-293.
-
(2009)
Cancer Cell
, vol.15
, pp. 283-293
-
-
Lee, H.1
Herrmann, A.2
Deng, J.H.3
Kujawski, M.4
Niu, G.5
Li, Z.6
Forman, S.7
Jove, R.8
Pardoll, D.M.9
Yu, H.10
-
7
-
-
70350500225
-
STATs in cancer inflammation and immunity: a leading role of Stat3
-
Yu H, Pardoll D and Jove R. STATs in cancer inflammation and immunity: a leading role of Stat3. Nat Rev Cancer 2009; 9: 798-809.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 798-809
-
-
Yu, H.1
Pardoll, D.2
Jove, R.3
-
8
-
-
70949094349
-
The novel JAK2 inhibitor, AZD1480, potently blocks Stat3 signaling and oncogenesis in solid tumors
-
Hedvat M, Huszar D, Herrmann A, Gozgit JM, Schroeder A, Sheehy A, Buettner R, Proia D, Kowolik CM, Xin H, Armstrong B, Bebernitz G, Weng S, Wang L, Ye M, McEachern K, Chen H, Morosini D, Bell K, Alimzhanov M, Ioannidis S, McCoon P, Cao ZA, Yu H, Jove R and Zinda M. The novel JAK2 inhibitor, AZD1480, potently blocks Stat3 signaling and oncogenesis in solid tumors. Cancer Cell 2009; 16: 487-497.
-
(2009)
Cancer Cell
, vol.16
, pp. 487-497
-
-
Hedvat, M.1
Huszar, D.2
Herrmann, A.3
Gozgit, J.M.4
Schroeder, A.5
Sheehy, A.6
Buettner, R.7
Proia, D.8
Kowolik, C.M.9
Xin, H.10
Armstrong, B.11
Bebernitz, G.12
Weng, S.13
Wang, L.14
Ye, M.15
McEachern, K.16
Chen, H.17
Morosini, D.18
Bell, K.19
Alimzhanov, M.20
Ioannidis, S.21
McCoon, P.22
Cao, Z.A.23
Yu, H.24
Jove, R.25
Zinda, M.26
more..
-
9
-
-
0030840464
-
STATs and gene regulation
-
Darnell JE Jr. STATs and gene regulation. Science 1997; 277: 1630-1635.
-
(1997)
Science
, vol.277
, pp. 1630-1635
-
-
Darnell Jr., J.E.1
-
10
-
-
0036251154
-
Stat proteins and oncogenesis
-
Bromberg J. Stat proteins and oncogenesis. J Clin Invest 2002; 109: 1139-1142.
-
(2002)
J Clin Invest
, vol.109
, pp. 1139-1142
-
-
Bromberg, J.1
-
11
-
-
31544458469
-
Persistent activation of stat3 signaling induces survivin gene expression and confers resistance to apoptosis in human breast cancer cells
-
Gritsko T, Williams A, Turkson J, Kaneko S, Bowman T, Huang M, Nam S, Eweis I, Diaz N, Sullivan D, Yoder S, Enkemann S, Eschrich S, Lee JH, Beam CA, Cheng J, Minton S, Muro-Cacho CA and Jove R. Persistent activation of stat3 signaling induces survivin gene expression and confers resistance to apoptosis in human breast cancer cells. Clin Cancer Res 2006; 12: 11-19.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 11-19
-
-
Gritsko, T.1
Williams, A.2
Turkson, J.3
Kaneko, S.4
Bowman, T.5
Huang, M.6
Nam, S.7
Eweis, I.8
Diaz, N.9
Sullivan, D.10
Yoder, S.11
Enkemann, S.12
Eschrich, S.13
Lee, J.H.14
Beam, C.A.15
Cheng, J.16
Minton, S.17
Muro-Cacho, C.A.18
Jove, R.19
-
12
-
-
0037206950
-
Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells
-
Real PJ, Sierra A, De Juan A, Segovia JC, Lopez-Vega JM and Fernandez-Luna JL. Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells. Oncogene 2002; 21: 7611-7618.
-
(2002)
Oncogene
, vol.21
, pp. 7611-7618
-
-
Real, P.J.1
Sierra, A.2
De Juan, A.3
Segovia, J.C.4
Lopez-Vega, J.M.5
Fernandez-Luna, J.L.6
-
13
-
-
2442685645
-
Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis
-
Xie TX, Wei D, Liu M, Gao AC, Ali-Osman F, Sawaya R and Huang S. Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis. Oncogene 2004; 23: 3550-3560.
-
(2004)
Oncogene
, vol.23
, pp. 3550-3560
-
-
Xie, T.X.1
Wei, D.2
Liu, M.3
Gao, A.C.4
Ali-Osman, F.5
Sawaya, R.6
Huang, S.7
-
14
-
-
37549003656
-
Expression of seven gastric cancer-associated genes and its relevance for Wnt, NF-kappaB and Stat3 signaling
-
Han JC, Zhang KL, Chen XY, Jiang HF, Kong QY, Sun Y, Wu ML, Huang L, Li H and Liu J. Expression of seven gastric cancer-associated genes and its relevance for Wnt, NF-kappaB and Stat3 signaling. APMIS 2007; 115: 1331-1343.
-
(2007)
APMIS
, vol.115
, pp. 1331-1343
-
-
Han, J.C.1
Zhang, K.L.2
Chen, X.Y.3
Jiang, H.F.4
Kong, Q.Y.5
Sun, Y.6
Wu, M.L.7
Huang, L.8
Li, H.9
Liu, J.10
-
15
-
-
58649101347
-
gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis
-
Bollrath J, Phesse TJ, von Burstin VA, Putoczki T, Bennecke M, Bateman T, Nebelsiek T, Lundgren-May T, Canli O, Schwitalla S, Matthews V, Schmid RM, Kirchner T, Arkan MC, Ernst M and Greten FR. gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis. Cancer Cell 2009; 15: 91-102.
-
(2009)
Cancer Cell
, vol.15
, pp. 91-102
-
-
Bollrath, J.1
Phesse, T.J.2
von Burstin, V.A.3
Putoczki, T.4
Bennecke, M.5
Bateman, T.6
Nebelsiek, T.7
Lundgren-May, T.8
Canli, O.9
Schwitalla, S.10
Matthews, V.11
Schmid, R.M.12
Kirchner, T.13
Arkan, M.C.14
Ernst, M.15
Greten, F.R.16
-
16
-
-
0033529704
-
Stat3 as an oncogene
-
Bromberg JF, Wrzeszczynska MH, Devgan G, Zhao Y, Pestell RG, Albanese C and Darnell JE Jr. Stat3 as an oncogene. Cell 1999; 98: 295-303.
-
(1999)
Cell
, vol.98
, pp. 295-303
-
-
Bromberg, J.F.1
Wrzeszczynska, M.H.2
Devgan, G.3
Zhao, Y.4
Pestell, R.G.5
Albanese, C.6
Darnell Jr., J.E.7
-
17
-
-
20944435271
-
Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target
-
Chiarle R, Simmons WJ, Cai H, Dhall G, Zamo A, Raz R, Karras JG, Levy DE and Inghirami G. Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target. Nat Med 2005; 11: 623-629.
-
(2005)
Nat Med
, vol.11
, pp. 623-629
-
-
Chiarle, R.1
Simmons, W.J.2
Cai, H.3
Dhall, G.4
Zamo, A.5
Raz, R.6
Karras, J.G.7
Levy, D.E.8
Inghirami, G.9
-
18
-
-
79953761842
-
Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression
-
Fukuda A, Wang SC, Morris JP 4th, Folias AE, Liou A, Kim GE, Akira S, Boucher KM, Firpo MA, Mulvihill SJ and Hebrok M. Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression. Cancer Cell 2011; 19: 441-455.
-
(2011)
Cancer Cell
, vol.19
, pp. 441-455
-
-
Fukuda, A.1
Wang, S.C.2
Morris IV, J.P.3
Folias, A.E.4
Liou, A.5
Kim, G.E.6
Akira, S.7
Boucher, K.M.8
Firpo, M.A.9
Mulvihill, S.J.10
Hebrok, M.11
-
19
-
-
58649108302
-
IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer
-
Grivennikov S, Karin E, Terzic J, Mucida D, Yu GY, Vallabhapurapu S, Scheller J, Rose-John S, Cheroutre H, Eckmann L and Karin M. IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer. Cancer Cell 2009; 15: 103-113.
-
(2009)
Cancer Cell
, vol.15
, pp. 103-113
-
-
Grivennikov, S.1
Karin, E.2
Terzic, J.3
Mucida, D.4
Yu, G.Y.5
Vallabhapurapu, S.6
Scheller, J.7
Rose-John, S.8
Cheroutre, H.9
Eckmann, L.10
Karin, M.11
-
20
-
-
78649982367
-
STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors
-
Lee H, Deng J, Kujawski M, Yang C, Liu Y, Herrmann A, Kortylewski M, Horne D, Somlo G, Forman S, Jove R and Yu H. STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors. Nat Med 2010; 16: 1421-1428.
-
(2010)
Nat Med
, vol.16
, pp. 1421-1428
-
-
Lee, H.1
Deng, J.2
Kujawski, M.3
Yang, C.4
Liu, Y.5
Herrmann, A.6
Kortylewski, M.7
Horne, D.8
Somlo, G.9
Forman, S.10
Jove, R.11
Yu, H.12
-
21
-
-
79953756112
-
Stat3/Socs3 activation by IL-6 transsignaling promotes progression of pancreatic intraepithelial neoplasia and development of pancreatic cancer
-
Lesina M, Kurkowski MU, Ludes K, Rose-John S, Treiber M, Klöppel G, Yoshimura A, Reindl W, Sipos B, Akira S, Schmid RM and Algül H. Stat3/Socs3 activation by IL-6 transsignaling promotes progression of pancreatic intraepithelial neoplasia and development of pancreatic cancer. Cancer Cell 2011; 19: 456-469.
-
(2011)
Cancer Cell
, vol.19
, pp. 456-469
-
-
Lesina, M.1
Kurkowski, M.U.2
Ludes, K.3
Rose-John, S.4
Treiber, M.5
Klöppel, G.6
Yoshimura, A.7
Reindl, W.8
Sipos, B.9
Akira, S.10
Schmid, R.M.11
Algül, H.12
-
22
-
-
33845865825
-
Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment
-
Yu H, Kortylewski M and Pardoll D. Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment. Nat Rev Immunol 2007; 7: 41-51.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 41-51
-
-
Yu, H.1
Kortylewski, M.2
Pardoll, D.3
-
23
-
-
63849197587
-
STAT3 expression in gastric cancer indicates a poor prognosis
-
Kim DY, Cha ST, Ahn DH, Kang HY, Kwon CI, Ko KH, Hwang SG, Park PW, Rim KS and Hong SP. STAT3 expression in gastric cancer indicates a poor prognosis. J Gastroenterol Hepatol 2009; 24: 646-651.
-
(2009)
J Gastroenterol Hepatol
, vol.24
, pp. 646-651
-
-
Kim, D.Y.1
Cha, S.T.2
Ahn, D.H.3
Kang, H.Y.4
Kwon, C.I.5
Ko, K.H.6
Hwang, S.G.7
Park, P.W.8
Rim, K.S.9
Hong, S.P.10
-
24
-
-
77956976681
-
Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
-
Biswas SK and Mantovani A. Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nat Immunol 2010; 11: 889-896.
-
(2010)
Nat Immunol
, vol.11
, pp. 889-896
-
-
Biswas, S.K.1
Mantovani, A.2
-
25
-
-
70349971417
-
In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses
-
Kortylewski M, Swiderski P, Herrmann A, Wang L, Kowolik C, Kujawski M, Lee H, Scuto A, Liu Y, Yang C, Deng J, Soifer HS, Raubitschek A, Forman S, Rossi JJ, Pardoll DM, Jove R and Yu H. In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses. Nat Biotechnol 2009; 27: 925-932.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 925-932
-
-
Kortylewski, M.1
Swiderski, P.2
Herrmann, A.3
Wang, L.4
Kowolik, C.5
Kujawski, M.6
Lee, H.7
Scuto, A.8
Liu, Y.9
Yang, C.10
Deng, J.11
Soifer, H.S.12
Raubitschek, A.13
Forman, S.14
Rossi, J.J.15
Pardoll, D.M.16
Jove, R.17
Yu, H.18
-
26
-
-
58649119388
-
Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment
-
Kortylewski M, Xin H, Kujawski M, Lee H, Liu Y, Harris T, Drake C, Pardoll D and Yu H. Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment. Cancer Cell 2009; 15: 114-123.
-
(2009)
Cancer Cell
, vol.15
, pp. 114-123
-
-
Kortylewski, M.1
Xin, H.2
Kujawski, M.3
Lee, H.4
Liu, Y.5
Harris, T.6
Drake, C.7
Pardoll, D.8
Yu, H.9
-
27
-
-
67650495415
-
IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway
-
Wang L, Yi T, Kortylewski M, Pardoll DM, Zeng D and Yu H. IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway. J Exp Med 2009; 206: 1457-1464.
-
(2009)
J Exp Med
, vol.206
, pp. 1457-1464
-
-
Wang, L.1
Yi, T.2
Kortylewski, M.3
Pardoll, D.M.4
Zeng, D.5
Yu, H.6
-
28
-
-
55849107422
-
Stat3 mediates myeloid-cell-dependent tumor angiogenesis
-
Kujawski M, Kortylewski M, Lee HY, Herrmann A, Kay H and Yu H. Stat3 mediates myeloid-cell-dependent tumor angiogenesis. J Clin Invest 2008; 118: 3367-3377.
-
(2008)
J Clin Invest
, vol.118
, pp. 3367-3377
-
-
Kujawski, M.1
Kortylewski, M.2
Lee, H.Y.3
Herrmann, A.4
Kay, H.5
Yu, H.6
-
29
-
-
84861399789
-
S1PR1-STAT3 signaling is crucial for myeloid cell colonization at future metastatic sites
-
Deng J, Liu Y, Lee H, Herrmann A, Zhang W, Zhang C, Shen S, Priceman SJ, Kujawski M, Pal SK, Raubitschek A, Hoon DS, Forman S, Figlin RA, Liu J, Jove R and Yu H. S1PR1-STAT3 signaling is crucial for myeloid cell colonization at future metastatic sites. Cancer Cell 2012; 21: 642-654.
-
(2012)
Cancer Cell
, vol.21
, pp. 642-654
-
-
Deng, J.1
Liu, Y.2
Lee, H.3
Herrmann, A.4
Zhang, W.5
Zhang, C.6
Shen, S.7
Priceman, S.J.8
Kujawski, M.9
Pal, S.K.10
Raubitschek, A.11
Hoon, D.S.12
Forman, S.13
Figlin, R.A.14
Liu, J.15
Jove, R.16
Yu, H.17
-
30
-
-
80655144746
-
Signal transducers and activators of transcription 3 (STAT3) directly regulates cytokine-induced fascin expression and is required for breast cancer cell migration
-
Snyder M, Huang XY and Zhang JJ. Signal transducers and activators of transcription 3 (STAT3) directly regulates cytokine-induced fascin expression and is required for breast cancer cell migration. J Biol Chem 2011; 286: 38886-388893.
-
(2011)
J Biol Chem
, vol.286
, pp. 38886-388893
-
-
Snyder, M.1
Huang, X.Y.2
Zhang, J.J.3
-
31
-
-
23444452377
-
Expression of p-STAT3 in human colorectal adenocarcinoma and adenoma; correlation with clinicopathological factors
-
Kusaba T, Nakayama T, Yamazumi K, Yakata Y, Yoshizaki A, Nagayasu T and Sekine I. Expression of p-STAT3 in human colorectal adenocarcinoma and adenoma; correlation with clinicopathological factors. J Clin Pathol 2005; 58: 833-838.
-
(2005)
J Clin Pathol
, vol.58
, pp. 833-838
-
-
Kusaba, T.1
Nakayama, T.2
Yamazumi, K.3
Yakata, Y.4
Yoshizaki, A.5
Nagayasu, T.6
Sekine, I.7
-
32
-
-
70249102728
-
Expression of activated signal transducer and activator of transcription-3 predicts poor prognosis in cervical squamous-cell carcinoma
-
Takemoto S, Ushijima K, Kawano K, Yamaguchi T, Terada A, Fujiyoshi N, Nishio S, Tsuda N, Ijichi M, Kakuma T, Kage M, Hori D and Kamura T. Expression of activated signal transducer and activator of transcription-3 predicts poor prognosis in cervical squamous-cell carcinoma. Br J Cancer 2009; 101: 967-972.
-
(2009)
Br J Cancer
, vol.101
, pp. 967-972
-
-
Takemoto, S.1
Ushijima, K.2
Kawano, K.3
Yamaguchi, T.4
Terada, A.5
Fujiyoshi, N.6
Nishio, S.7
Tsuda, N.8
Ijichi, M.9
Kakuma, T.10
Kage, M.11
Hori, D.12
Kamura, T.13
-
33
-
-
81855185596
-
Inhibition of Stat3 activation by sanguinarine suppresses prostate cancer cell growth and invasion
-
Sun M, Liu C, Nadiminty N, Lou W, Zhu Y, Yang J, Evans CP, Zhou Q and Gao AC. Inhibition of Stat3 activation by sanguinarine suppresses prostate cancer cell growth and invasion. Prostate 2012; 72: 82-89.
-
(2012)
Prostate
, vol.72
, pp. 82-89
-
-
Sun, M.1
Liu, C.2
Nadiminty, N.3
Lou, W.4
Zhu, Y.5
Yang, J.6
Evans, C.P.7
Zhou, Q.8
Gao, A.C.9
-
34
-
-
34047259844
-
Expression of p-STAT3 in human gastric carcinoma: significant correlation in tumour invasion and prognosis
-
Yakata Y, Nakayama T, Yoshizaki A, Kusaba T, Inoue K and Sekine I. Expression of p-STAT3 in human gastric carcinoma: significant correlation in tumour invasion and prognosis. Int J Oncol 2007; 30: 437-442.
-
(2007)
Int J Oncol
, vol.30
, pp. 437-442
-
-
Yakata, Y.1
Nakayama, T.2
Yoshizaki, A.3
Kusaba, T.4
Inoue, K.5
Sekine, I.6
-
35
-
-
84867337093
-
Constitutive activation of STAT3 is predictive of poor prognosis in human gastric cancer
-
Xiong H, Du W, Wang JL, Wang YC, Tang JT, Hong J and Fang JY. Constitutive activation of STAT3 is predictive of poor prognosis in human gastric cancer. J Mol Med (Berl) 2012; 90: 1037-1046.
-
(2012)
J Mol Med (Berl)
, vol.90
, pp. 1037-1046
-
-
Xiong, H.1
Du, W.2
Wang, J.L.3
Wang, Y.C.4
Tang, J.T.5
Hong, J.6
Fang, J.Y.7
|