P38δ MAPK: A novel regulator of NLRP3 inflammasome activation with increased expression in coronary atherogenesis

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 36, Issue 9, 2016, Pages 1937-1946

  Rajamäki, Kristiina ^a,b   Mäyränpää, Mikko I ^b,c   Risco, Ana ^d   Tuimala, Jarno ^e   Nurmi, Katariina ^a   Cuenda, Ana ^d   Eklund, Kari K ^b,c   Öörni, Katariina ^a   Kovanen, Petri T ^a  

^a WIHURI RESEARCH INSTITUTE   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^d CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^e RS koulutus   (Finland)

Author keywords

Coronary artery disease; Inflammation; Innate immunity; Interleukin; Macrophage

Indexed keywords

ADENOSINE TRIPHOSPHATE; CHOLESTEROL; CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA CONVERTING ENZYME; MITOGEN ACTIVATED PROTEIN KINASE P38; HLA ANTIGEN CLASS 2; MHC CLASS II TRANSACTIVATOR PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 13; NLRP3 PROTEIN, HUMAN; NUCLEAR PROTEIN; TRANSACTIVATOR PROTEIN;

ARTICLE; ATHEROGENESIS; ATHEROSCLEROTIC PLAQUE; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; ENZYME ACTIVATION; FOAM CELL; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INNATE IMMUNITY; MACROPHAGE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; REGULATORY MECHANISM; UPREGULATION; CELL CULTURE; CORONARY ARTERY DISEASE; CORONARY BLOOD VESSEL; CRYSTALLIZATION; DNA MICROARRAY; ENZYMOLOGY; GENE EXPRESSION PROFILING; GENETICS; MALE; METABOLISM; MIDDLE AGED; NECROSIS; PATHOLOGY; PRIMARY CELL CULTURE; PROCEDURES; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TIME FACTOR;

ADENOSINE TRIPHOSPHATE; CELLS, CULTURED; CHOLESTEROL; CORONARY ARTERY DISEASE; CORONARY VESSELS; CRYSTALLIZATION; ENZYME ACTIVATION; FOAM CELLS; GENE EXPRESSION PROFILING; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; INFLAMMASOMES; MALE; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASE 13; NECROSIS; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; NUCLEAR PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PLAQUE, ATHEROSCLEROTIC; PRIMARY CELL CULTURE; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TIME FACTORS; TRANS-ACTIVATORS; UP-REGULATION;

EID: 84978766925     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.115.307312     Document Type: Article

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