On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver

Nature Medicine

Volumn 22, Issue 8, 2016, Pages 945-951

  Theurl, Igor ^a,b   Hilgendorf, Ingo ^a,c   Nairz, Manfred ^a   Tymoszuk, Piotr ^b   Haschka, David ^b   Asshoff, Malte ^b   He, Shun ^a   Gerhardt, Louisa M S ^a   Holderried, Tobias A W ^d   Seifert, Markus ^b   Sopper, Sieghart ^b   Fenn, Ashley M ^a   Anzai, Atsushi ^a   Rattik, Sara ^a   McAlpine, Cameron ^a   Theurl, Milan ^b   Wieghofer, Peter ^c,e   Iwamoto, Yoshiko ^a   Weber, Georg F ^a   Harder, Nina K ^a   Chousterman, Benjamin G ^a   Arvedson, Tara L ^f   McKee, Mary ^a   Wang, Fudi ^g   Lutz, Oliver M D ^h   Rezoagli, Emanuele ^a   Babitt, Jodie L ^a   Berra, Lorenzo ^a   Prinz, Marco ^c,e   Nahrendorf, Matthias ^a   Weiss, Guenter ^b   Weissleder, Ralph ^a,i   Lin, Herbert Y ^a   Swirski, Filip K ^a   more..

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^c UNIVERSITY OF FREIBURG   (Germany)

^d UNIVERSITY HOSPITAL BONN   (Germany)

^e UNIVERSITY OF FREIBURG   (Germany)

^f AMGEN INC   (United States)

^g ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^h ADSI Austrian Drug Screening Institute GmbH   (Austria)

ⁱ HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FERROPORTIN 1; IMMUNOGLOBULIN; IRON; LYMPHOCYTE ANTIGEN; MUCIN; TAMOXIFEN; TRANSCRIPTION FACTOR NRF2; CATION TRANSPORT PROTEIN; COLONY STIMULATING FACTOR 1; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; LY ANTIGEN; LY-6C ANTIGEN, MOUSE; MEMBRANE PROTEIN; METAL TRANSPORTING PROTEIN 1; TIM-4 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL POPULATION; CELL SUSPENSION; CLINICAL ARTICLE; CONTROLLED STUDY; EMBRYO; ERYTHROCYTE; ERYTHROCYTE LIFESPAN; ERYTHROPHAGOCYTOSIS; FEMALE; FLOW CYTOMETRY; HEMOLYTIC ANEMIA; HOMEOSTASIS; HUMAN; HUMAN CELL; IN VIVO STUDY; KIDNEY INJURY; KUPFFER CELL; LIVER CELL; LIVER INJURY; LIVER RESECTION; LOBECTOMY; MACROPHAGE; MALE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SICKLE CELL ANEMIA; SPLENECTOMY; T LYMPHOCYTE; ANEMIA; ANIMAL; CELL DIFFERENTIATION; CYTOLOGY; DISEASE MODEL; INFLAMMATION; LIVER; METABOLISM; SPLEEN;

ANEMIA; ANEMIA, HEMOLYTIC; ANEMIA, SICKLE CELL; ANIMALS; ANTIGENS, LY; CATION TRANSPORT PROTEINS; CELL DIFFERENTIATION; DISEASE MODELS, ANIMAL; ERYTHROCYTES; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HEPATOCYTES; INFLAMMATION; IRON; KUPFFER CELLS; LIVER; MACROPHAGE COLONY-STIMULATING FACTOR; MACROPHAGES; MEMBRANE PROTEINS; MICE; MONOCYTES; NF-E2-RELATED FACTOR 2; SPLEEN;

EID: 84978733946     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.4146     Document Type: Article

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