Dorsomorphin homologue 1, a highly selective small-molecule bone morphogenetic protein inhibitor, suppresses medial artery calcification

Journal of Vascular Surgery

Volumn 66, Issue 2, 2017, Pages 586-593

  Lin, Tonghui ^a   Wang, Xue Lin ^a   Zettervall, Sara L ^a   Cai, Yujun ^a   Guzman, Raul J ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALIZARIN RED S; ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN RECEPTOR 1; DORSOMORPHIN; DORSOMORPHIN HOMOLOG 1; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MYOSIN HEAVY CHAIN; PHOSPHATE; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; UNCLASSIFIED DRUG; BMPR1A PROTEIN, HUMAN; BMPR1A PROTEIN, RAT; BONE MORPHOGENETIC PROTEIN; DMH1 COMPOUND; PYRAZOLE DERIVATIVE; QUINOLINE DERIVATIVE;

ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTIC SMOOTH MUSCLE CELL; ARTERY CALCIFICATION; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; ANTAGONISTS AND INHIBITORS; AORTIC DISEASES; BONE DEVELOPMENT; CELL CULTURE; DRUG EFFECTS; METABOLISM; ORGAN CULTURE TECHNIQUE; PATHOLOGY; SIGNAL TRANSDUCTION; SMOOTH MUSCLE CELL; SPRAGUE DAWLEY RAT; THORACIC AORTA; VASCULAR CALCIFICATION; VASCULAR SMOOTH MUSCLE;

ANIMALS; AORTA, THORACIC; AORTIC DISEASES; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE I; BONE MORPHOGENETIC PROTEINS; CELLS, CULTURED; HUMANS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; ORGAN CULTURE TECHNIQUES; OSTEOGENESIS; PHOSPHATES; PYRAZOLES; QUINOLINES; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; VASCULAR CALCIFICATION;

EID: 84978372362     PISSN: 07415214     EISSN: 10976809     Source Type: Journal    
DOI: 10.1016/j.jvs.2016.03.462     Document Type: Article

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