메뉴 건너뛰기




Volumn 6, Issue 5, 2016, Pages

Modulation of natural killer cell functions by interactions between 2B4 and CD48 in cis and in trans

Author keywords

2B4; CD48; Cytotoxicity; Natural killer cells; Surface receptors

Indexed keywords

CD244 PROTEIN, HUMAN; CD48 ANTIGEN; CD48 PROTEIN, HUMAN; PROTEIN BINDING; SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE;

EID: 84978299781     PISSN: None     EISSN: 20462441     Source Type: Journal    
DOI: 10.1098/rsob.160010     Document Type: Article
Times cited : (16)

References (50)
  • 1
    • 1542380606 scopus 로고    scopus 로고
    • Unravelling natural killer cell function: Triggering and inhibitory human NK receptors
    • Moretta L, Moretta A. 2004 Unravelling natural killer cell function: triggering and inhibitory human NK receptors. EMBO J. 23, 255-259. (doi:10.1038/sj. emboj.7600019)
    • (2004) EMBO J. , vol.23 , pp. 255-259
    • Moretta, L.1    Moretta, A.2
  • 2
    • 42449102990 scopus 로고    scopus 로고
    • Up on the tightrope: Natural killer cell activation and inhibition
    • Lanier LL. 2008 Up on the tightrope: natural killer cell activation and inhibition. Nat. Immunol. 9, 495-502. (doi:10.1038/ni1581)
    • (2008) Nat. Immunol. , vol.9 , pp. 495-502
    • Lanier, L.L.1
  • 3
    • 33244455863 scopus 로고    scopus 로고
    • Immune regulation by SLAM family receptors and SAP-related adaptors
    • Veillette A. 2006 Immune regulation by SLAM family receptors and SAP-related adaptors. Nat. Rev. Immunol. 6, 56-66. (doi:10.1038/nri1761)
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 56-66
    • Veillette, A.1
  • 4
    • 38449109750 scopus 로고    scopus 로고
    • Regulation of NK cell activity by 2B4, NTB-A and CRACC
    • Claus M, Meinke S, Bhat R, Watzl C. 2008 Regulation of NK cell activity by 2B4, NTB-A and CRACC. Front. Biosci. 13, 956-965. (doi:10.2741/2735)
    • (2008) Front. Biosci. , vol.13 , pp. 956-965
    • Claus, M.1    Meinke, S.2    Bhat, R.3    Watzl, C.4
  • 5
    • 0031743839 scopus 로고    scopus 로고
    • 2B4, the natural killer and T cell immunoglobulin superfamily surface protein, is a ligand for CD48
    • Brown MH, Boles K, van der Merwe PA, Kumar V, Mathew PA, Barclay AN. 1998 2B4, the natural killer and T cell immunoglobulin superfamily surface protein, is a ligand for CD48. J. Exp. Med. 188, 2083-2090. (doi:10.1084/jem.188.11.2083)
    • (1998) J. Exp. Med. , vol.188 , pp. 2083-2090
    • Brown, M.H.1    Boles, K.2    Van Der Merwe, P.A.3    Kumar, V.4    Mathew, P.A.5    Barclay, A.N.6
  • 6
    • 0032406389 scopus 로고    scopus 로고
    • Identification of the 2B4 molecule as a counter-receptor for CD48
    • Latchman Y, McKay PF, Reiser H. 1998 Identification of the 2B4 molecule as a counter-receptor for CD48. J. Immunol. 161, 5809-5812.
    • (1998) J. Immunol. , vol.161 , pp. 5809-5812
    • Latchman, Y.1    McKay, P.F.2    Reiser, H.3
  • 7
    • 0033564638 scopus 로고    scopus 로고
    • Cutting edge: Human 2B4, an activating NK cell receptor, recruits the protein tyrosine phosphatase SHP-2 and the adaptor signaling protein SAP
    • Tangye SG, Lazetic S, Woollatt E, Sutherland GR, Lanier LL, Phillips JH. 1999 Cutting edge: human 2B4, an activating NK cell receptor, recruits the protein tyrosine phosphatase SHP-2 and the adaptor signaling protein SAP. J. Immunol. 162, 6981- 6985.
    • (1999) J. Immunol , vol.162 , pp. 6981-6985
    • Tangye, S.G.1    Lazetic, S.2    Woollatt, E.3    Sutherland, G.R.4    Lanier, L.L.5    Phillips, J.H.6
  • 8
    • 20444389785 scopus 로고    scopus 로고
    • Molecular basis for positive and negative signaling by the natural killer cell receptor 2B4 (CD244)
    • Eissmann P, Beauchamp L, Wooters J, Tilton JC, Long EO, Watzl C. 2005 Molecular basis for positive and negative signaling by the natural killer cell receptor 2B4 (CD244). Blood 105, 4722-4729. (doi:10.1182/blood-2004-09-3796)
    • (2005) Blood , vol.105 , pp. 4722-4729
    • Eissmann, P.1    Beauchamp, L.2    Wooters, J.3    Tilton, J.C.4    Long, E.O.5    Watzl, C.6
  • 9
    • 30144443832 scopus 로고    scopus 로고
    • Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion
    • Bryceson YT, March ME, Ljunggren H-G, Long EO. 2006 Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion. Blood 107, 159-166. (doi:10. 1182/blood-2005-04-1351)
    • (2006) Blood , vol.107 , pp. 159-166
    • Bryceson, Y.T.1    March, M.E.2    Ljunggren, H.-G.3    Long, E.O.4
  • 10
    • 79952774803 scopus 로고    scopus 로고
    • 2B4 engagement mediates rapid LFA-1 and actindependent NK cell adhesion to tumor cells as measured by single cell force spectroscopy
    • Hoffmann SC, Cohnen A, Ludwig T, Watzl C. 2011 2B4 engagement mediates rapid LFA-1 and actindependent NK cell adhesion to tumor cells as measured by single cell force spectroscopy. J. Immunol. 186, 2757-2764. (doi:10.4049/ jimmunol.1002867)
    • (2011) J. Immunol. , vol.186 , pp. 2757-2764
    • Hoffmann, S.C.1    Cohnen, A.2    Ludwig, T.3    Watzl, C.4
  • 11
    • 33845581207 scopus 로고    scopus 로고
    • Regulation of 2B4 (CD244)-mediated NK cell activation by ligand-induced receptor modulation
    • Sandusky MM, Messmer B, Watzl C. 2006 Regulation of 2B4 (CD244)-mediated NK cell activation by ligand-induced receptor modulation. Eur. J. Immunol. 36, 3268-3276. (doi:10.1002/eji. 200636146)
    • (2006) Eur. J. Immunol. , vol.36 , pp. 3268-3276
    • Sandusky, M.M.1    Messmer, B.2    Watzl, C.3
  • 12
    • 33847170286 scopus 로고    scopus 로고
    • Human natural killer cell receptor 2B4 (CD244) down-regulates its own expression by reduced promoter activity at an Ets element
    • Mathew SO, Vaidya SV, Kim JR, Mathew PA. 2007 Human natural killer cell receptor 2B4 (CD244) down-regulates its own expression by reduced promoter activity at an Ets element. Biochem. Biophys. Res. Commun. 355, 483- 487. (doi:10. 1016/j.bbrc.2007.01.176)
    • (2007) Biochem. Biophys. Res. Commun. , vol.355 , pp. 483-487
    • Mathew, S.O.1    Vaidya, S.V.2    Kim, J.R.3    Mathew, P.A.4
  • 13
    • 35348933148 scopus 로고    scopus 로고
    • Structure of natural killer receptor 2B4 bound to CD48 reveals basis for heterophilic recognition in signaling lymphocyte activation molecule family
    • Velikovsky CA, Deng L, Chlewicki LK, Fernández MM, Kumar V, Mariuzza RA. 2007 Structure of natural killer receptor 2B4 bound to CD48 reveals basis for heterophilic recognition in signaling lymphocyte activation molecule family. Immunity 27, 572-584. (doi:10.1016/j.immuni.2007.08.019)
    • (2007) Immunity , vol.27 , pp. 572-584
    • Velikovsky, C.A.1    Deng, L.2    Chlewicki, L.K.3    Fernández, M.M.4    Kumar, V.5    Mariuzza, R.A.6
  • 14
    • 17844390629 scopus 로고    scopus 로고
    • NMR structure of the natural killer cell receptor 2B4 (CD244): Implications for ligand recognition
    • Ames JB, Vyas V, Lusin JD, Mariuzza RA. 2005 NMR structure of the natural killer cell receptor 2B4 (CD244): implications for ligand recognition. Biochemistry 44, 6416- 6423. (doi:10.1021/ bi050139s)
    • (2005) Biochemistry , vol.44 , pp. 6416-6423
    • Ames, J.B.1    Vyas, V.2    Lusin, J.D.3    Mariuzza, R.A.4
  • 15
    • 0029930984 scopus 로고    scopus 로고
    • The structure and ligand interactions of CD2: Implications for T-cell function
    • Davis SJ, van der Merwe PA. 1996 The structure and ligand interactions of CD2: implications for T-cell function. Immunol. Today 17, 177-187. (doi:10. 1016/0167-5699(96)80617-7)
    • (1996) Immunol. Today , vol.17 , pp. 177-187
    • Davis, S.J.1    An Der Merwe, P.A.2
  • 16
    • 41149093503 scopus 로고    scopus 로고
    • Cis interactions of immunoreceptors with MHC and non-MHC ligands
    • Held W, Mariuzza RA. 2008 Cis interactions of immunoreceptors with MHC and non-MHC ligands. Nat. Rev. Immunol. 8, 269-278. (doi:10.1038/nri2278)
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 269-278
    • Held, W.1    Mariuzza, R.A.2
  • 17
    • 67650497723 scopus 로고    scopus 로고
    • Essential role of the Ly49A stalk region for immunological synapse formation and signaling
    • Ito D, Iizuka Y-M, Katepalli MP, Iizuka K. 2009 Essential role of the Ly49A stalk region for immunological synapse formation and signaling. Proc. Natl Acad. Sci. USA 106, 11 264-11 269. (doi:10.1073/pnas.0900664106)
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 11264-11269
    • Ito, D.1    Iizuka, Y.-M.2    Katepalli, M.P.3    Iizuka, K.4
  • 18
    • 34247248179 scopus 로고    scopus 로고
    • Stable masking by H-2Dd cis ligand limits Ly49A relocalization to the site of NK cell/target cell contact
    • Back J, Chalifour A, Scarpellino L, Held W. 2007 Stable masking by H-2Dd cis ligand limits Ly49A relocalization to the site of NK cell/target cell contact. Proc. Natl Acad. Sci. USA 104, 3978-3983. (doi:10.1073/pnas.0607418104)
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 3978-3983
    • Back, J.1    Chalifour, A.2    Scarpellino, L.3    Held, W.4
  • 19
    • 77951649964 scopus 로고    scopus 로고
    • Effects of MHC class I alleles on licensing of Ly49A+ NK cells
    • Jonsson AH, Yang L, Kim S, Taffner SM, Yokoyama WM. 2010 Effects of MHC class I alleles on licensing of Ly49A+ NK cells. J. Immunol. 184, 3424-3432. (doi:10.4049/jimmunol.0904057)
    • (2010) J. Immunol. , vol.184 , pp. 3424-3432
    • Jonsson, A.H.1    Yang, L.2    Kim, S.3    Taffner, S.M.4    Yokoyama, W.M.5
  • 20
    • 61949439062 scopus 로고    scopus 로고
    • A role for cis interaction between the inhibitory Ly49A receptor and MHC class I for natural killer cell education
    • Chalifour A et al. 2009 A role for cis interaction between the inhibitory Ly49A receptor and MHC class I for natural killer cell education. Immunity 30, 337-347. (doi:10.1016/j.immuni.2008.12.019)
    • (2009) Immunity , vol.30 , pp. 337-347
    • Chalifour, A.1
  • 21
    • 0034795143 scopus 로고    scopus 로고
    • Inhibition of IgE-mediated mast cell activation by the paired Ig-like receptor PIR-B
    • Uehara T et al. 2001 Inhibition of IgE-mediated mast cell activation by the paired Ig-like receptor PIR-B. J. Clin. Invest. 108, 1041- 1050. (doi:10. 1172/JCI12195)
    • (2001) J. Clin. Invest. , vol.108 , pp. 1041-1050
    • Uehara, T.1
  • 22
    • 0033592854 scopus 로고    scopus 로고
    • Constitutive tyrosine phosphorylation of the inhibitory paired Ig-like receptor PIR-B
    • Ho LH, Uehara T, Chen CC, Kubagawa H, Cooper MD. 1999 Constitutive tyrosine phosphorylation of the inhibitory paired Ig-like receptor PIR-B. Proc. Natl Acad. Sci. USA 96, 15 086-15 090. (doi:10.1073/ pnas.96.26.15086)
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 15086-15090
    • Ho, L.H.1    Uehara, T.2    Chen, C.C.3    Kubagawa, H.4    Cooper, M.D.5
  • 23
    • 0033781975 scopus 로고    scopus 로고
    • Glycosylphosphatidylinositol (GPI)-deficient Jurkat T cells as a model to study functions of GPI-anchored proteins
    • Bastisch I, Tiede A, Deckert M, Ziolek A, Schmidt RE, Schubert J. 2000 Glycosylphosphatidylinositol (GPI)-deficient Jurkat T cells as a model to study functions of GPI-anchored proteins. Clin. Exp. Immunol. 122, 49-54. (doi:10.1046/j.1365-2249. 2000.01350.x)
    • (2000) Clin. Exp. Immunol. , vol.122 , pp. 49-54
    • Bastisch, I.1    Tiede, A.2    Deckert, M.3    Ziolek, A.4    Schmidt, R.E.5    Schubert, J.6
  • 24
    • 23244449293 scopus 로고    scopus 로고
    • Mutational analysis of the human 2B4 (CD244)/CD48 interaction: Lys68 and Glu70 in the V domain of 2B4 are critical for CD48 binding and functional activation of NK cells
    • Mathew SO, Kumaresan PR, Lee JK, Huynh VT, Mathew PA. 2005 Mutational analysis of the human 2B4 (CD244)/CD48 interaction: Lys68 and Glu70 in the V domain of 2B4 are critical for CD48 binding and functional activation of NK cells. J. Immunol. 175, 1005- 1013. (doi:10.4049/jimmunol.175. 2.1005)
    • (2005) J. Immunol , vol.175 , pp. 1005-1013
    • Mathew, S.O.1    Kumaresan, P.R.2    Lee, J.K.3    Huynh, V.T.4    Mathew, P.A.5
  • 25
    • 78649795438 scopus 로고    scopus 로고
    • Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody
    • Freeman MM, Seaman MS, Rits-Volloch S, Hong X, Kao CY, Ho DD, Chen B. 2010 Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody. Structure 18, 1632-1641. (doi:10.1016/j.str.2010.09.017)
    • (2010) Structure , vol.18 , pp. 1632-1641
    • Freeman, M.M.1    Seaman, M.S.2    Rits-Volloch, S.3    Hong, X.4    Kao, C.Y.5    Ho, D.D.6    Chen, B.7
  • 26
    • 0034292341 scopus 로고    scopus 로고
    • NK cell inhibitory receptors prevent tyrosine phosphorylation of the activation receptor 2B4 (CD244)
    • Watzl C, Stebbins CC, Long EO. 2000 NK cell inhibitory receptors prevent tyrosine phosphorylation of the activation receptor 2B4 (CD244). J. Immunol. 165, 3545-3548. (doi:10. 4049/jimmunol.165.7.3545)
    • (2000) J. Immunol , vol.165 , pp. 3545-3548
    • Watzl, C.1    Stebbins, C.C.2    Long, E.O.3
  • 27
    • 0034528476 scopus 로고    scopus 로고
    • Analysis of the molecular mechanism involved in 2B4-mediated NK cell activation: Evidence that human 2B4 is physically and functionally associated with the linker for activation of T cells
    • Bottino C, Augugliaro R, Castriconi R, Nanni M, Biassoni R, Moretta L, Moretta A. 2000 Analysis of the molecular mechanism involved in 2B4-mediated NK cell activation: evidence that human 2B4 is physically and functionally associated with the linker for activation of T cells. Eur. J. Immunol. 30, 3718-3722. (doi:10.1002/1521-4141(200012) 30:12<3718::AID-IMMU3718>3.0.CO;2-I)
    • (2000) Eur. J. Immunol. , vol.30 , pp. 3718-3722
    • Bottino, C.1    Augugliaro, R.2    Castriconi, R.3    Nanni, M.4    Biassoni, R.5    Moretta, L.6    Moretta, A.7
  • 28
    • 0037244127 scopus 로고    scopus 로고
    • Natural killer cell inhibitory receptors block actin cytoskeleton-dependent recruitment of 2B4 (CD244) to lipid rafts
    • Watzl C, Long EO. 2003 Natural killer cell inhibitory receptors block actin cytoskeleton-dependent recruitment of 2B4 (CD244) to lipid rafts. J. Exp. Med. 197, 77-85. (doi:10.1084/jem.20020427)
    • (2003) J. Exp. Med. , vol.197 , pp. 77-85
    • Watzl, C.1    Long, E.O.2
  • 29
    • 34247323402 scopus 로고    scopus 로고
    • Cis binding between inhibitory receptors and MHC class I can regulate mast cell activation
    • Masuda A, Nakamura A, Maeda T, Sakamoto Y, Takai T. 2007 Cis binding between inhibitory receptors and MHC class I can regulate mast cell activation. J. Exp. Med. 204, 907- 920. (doi:10. 1084/jem.20060631)
    • (2007) J. Exp. Med , vol.204 , pp. 907-920
    • Masuda, A.1    Nakamura, A.2    Maeda, T.3    Sakamoto, Y.4    Takai, T.5
  • 31
    • 0037029667 scopus 로고    scopus 로고
    • The ligand-binding domain of CD22 is needed for inhibition of the B cell receptor signal, as demonstrated by a novel human CD22-specific inhibitor compound
    • Kelm S, Gerlach J, Brossmer R, Danzer CP, Nitschke L. 2002 The ligand-binding domain of CD22 is needed for inhibition of the B cell receptor signal, as demonstrated by a novel human CD22-specific inhibitor compound. J. Exp. Med. 195, 1207- 1213. (doi:10.1084/jem.20011783)
    • (2002) J. Exp. Med. , vol.195 , pp. 1207-1213
    • Kelm, S.1    Gerlach, J.2    Brossmer, R.3    Danzer, C.P.4    Nitschke, L.5
  • 32
    • 0037029637 scopus 로고    scopus 로고
    • Sialic acid binding domains of CD22 are required for negative regulation of B cell receptor signaling
    • Jin L, McLean PA, Neel BG, Wortis HH. 2002 Sialic acid binding domains of CD22 are required for negative regulation of B cell receptor signaling. J. Exp. Med. 195, 1199- 1205. (doi:10.1084/jem. 20011796)
    • (2002) J. Exp. Med. , vol.195 , pp. 1199-1205
    • Jin, L.1    McLean, P.A.2    Neel, B.G.3    Wortis, H.H.4
  • 33
    • 1942437467 scopus 로고    scopus 로고
    • Masking of CD22 by cis ligands does not prevent redistribution of CD22 to sites of cell contact
    • Collins BE, Blixt O, DeSieno AR, Bovin N, Marth JD, Paulson JC. 2004 Masking of CD22 by cis ligands does not prevent redistribution of CD22 to sites of cell contact. Proc. Natl Acad. Sci. USA 101, 6104-6109. (doi:10.1073/pnas. 0400851101)
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 6104-6109
    • Collins, B.E.1    Blixt, O.2    DeSieno, A.R.3    Bovin, N.4    Marth, J.D.5    Paulson, J.C.6
  • 35
    • 0034618065 scopus 로고    scopus 로고
    • X-linked lymphoproliferative disease. 2b4 molecules displaying inhibitory rather than activating function are responsible for the inability of natural killer cells to kill Epstein-Barr virus-infected cells
    • Parolini S et al. 2000 X-linked lymphoproliferative disease. 2b4 molecules displaying inhibitory rather than activating function are responsible for the inability of natural killer cells to kill Epstein-Barr virus-infected cells. J. Exp. Med. 192, 337-346. (doi:10.1084/jem.192.3.337)
    • (2000) J. Exp. Med. , vol.192 , pp. 337-346
    • Parolini, S.1
  • 36
    • 78149479192 scopus 로고    scopus 로고
    • Mechanism of Induction of NK activation by 2B4 (CD244) via its cognate ligand
    • Sinha SK, Gao N, Guo Y, Yuan D. 2010 Mechanism of Induction of NK activation by 2B4 (CD244) via its cognate ligand. J. Immunol. 185, 5205-5210. (doi:10.4049/jimmunol.1002518)
    • (2010) J. Immunol. , vol.185 , pp. 5205-5210
    • Sinha, S.K.1    Gao, N.2    Guo, Y.3    Yuan, D.4
  • 39
    • 33751524059 scopus 로고    scopus 로고
    • Probing the cis interactions of the inhibitory receptor Siglec-7 with alpha2,8-disialylated ligands on natural killer cells and other leukocytes using glycan-specific antibodies and by analysis of alpha2,8-sialyltransferase gene expression
    • Avril T, North SJ, Haslam SM, Willison HJ, Crocker PR. 2006 Probing the cis interactions of the inhibitory receptor Siglec-7 with alpha2,8-disialylated ligands on natural killer cells and other leukocytes using glycan-specific antibodies and by analysis of alpha2,8-sialyltransferase gene expression. J. Leukoc. Biol. 80, 787-796. (doi:10. 1189/jlb.1005559)
    • (2006) J. Leukoc. Biol. , vol.80 , pp. 787-796
    • Avril, T.1    North, S.J.2    Haslam, S.M.3    Willison, H.J.4    Crocker, P.R.5
  • 40
    • 73349101076 scopus 로고    scopus 로고
    • T cell intrinsic heterodimeric complexes between HVEM and BTLA determine receptivity to the surrounding microenvironment
    • Cheung TC et al. 2009 T cell intrinsic heterodimeric complexes between HVEM and BTLA determine receptivity to the surrounding microenvironment. J. Immunol. 183, 7286-7296. (doi:10.4049/ jimmunol.0902490)
    • (2009) J. Immunol. , vol.183 , pp. 7286-7296
    • Cheung, T.C.1
  • 41
    • 84887463670 scopus 로고    scopus 로고
    • Education of murine NK cells requires both cis and trans recognition of MHC class I molecules
    • Bessoles S, Angelov GS, Back J, Leclercq G, Vivier E, Held W. 2013 Education of murine NK cells requires both cis and trans recognition of MHC class I molecules. J. Immunol. 191, 5044-5051. (doi:10. 4049/jimmunol.1301971)
    • (2013) J. Immunol. , vol.191 , pp. 5044-5051
    • Bessoles, S.1    Angelov, G.S.2    Back, J.3    Leclercq, G.4    Vivier, E.5    Held, W.6
  • 42
    • 84860421890 scopus 로고    scopus 로고
    • Cis- trans interactions of cell surface receptors: Biological roles and structural basis
    • Held W, Mariuzza RA. 2011 Cis- trans interactions of cell surface receptors: biological roles and structural basis. Cell Mol. Life Sci. 68, 3469-3478. (doi:10.1007/s00018-011-0798-z)
    • (2011) Cell Mol. Life Sci. , vol.68 , pp. 3469-3478
    • Held, W.1    Mariuzza, R.A.2
  • 43
    • 77949532253 scopus 로고    scopus 로고
    • Education of human natural killer cells by activating killer cell immunoglobulin-like receptors
    • Fauriat C, Ivarsson MA, Ljunggren H-G, Malmberg K-J, Michaëlsson J. 2010 Education of human natural killer cells by activating killer cell immunoglobulin-like receptors. Blood 115, 1166-1174. (doi:10.1182/blood-2009-09-245746)
    • (2010) Blood , vol.115 , pp. 1166-1174
    • Fauriat, C.1    Ivarsson, M.A.2    Ljunggren, H.-G.3    Malmberg, K.-J.4    Michaëlsson, J.5
  • 44
    • 1642275490 scopus 로고    scopus 로고
    • Analysis of the activating receptors and cytolytic function of human natural killer cells undergoing in vivo differentiation after allogeneic bone marrow transplantation
    • Vitale C, Chiossone L, Morreale G, Lanino E, Cottalasso F, Moretti S, Dini G, Moretta L, Mingari MC. 2004 Analysis of the activating receptors and cytolytic function of human natural killer cells undergoing in vivo differentiation after allogeneic bone marrow transplantation. Eur. J. Immunol. 34, 455-460. (doi:10.1002/eji. 200324668)
    • (2004) Eur. J. Immunol. , vol.34 , pp. 455-460
    • Vitale, C.1    Chiossone, L.2    Morreale, G.3    Lanino, E.4    Cottalasso, F.5    Moretti, S.6    Dini, G.7    Moretta, L.8    Mingari, M.C.9
  • 45
    • 0037007090 scopus 로고    scopus 로고
    • Early expression of triggering receptors and regulatory role of 2B4 in human natural killer cell precursors undergoing in vitro differentiation
    • Sivori S, Falco M, Marcenaro E, Parolini S, Biassoni R, Bottino C, Moretta L, Moretta A. 2002 Early expression of triggering receptors and regulatory role of 2B4 in human natural killer cell precursors undergoing in vitro differentiation. Proc. Natl Acad. Sci. USA 99, 4526-4531. (doi:10.1073/pnas. 072065999)
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 4526-4531
    • Sivori, S.1    Falco, M.2    Marcenaro, E.3    Parolini, S.4    Biassoni, R.5    Bottino, C.6    Moretta, L.7    Moretta, A.8
  • 46
    • 84866598352 scopus 로고    scopus 로고
    • Killer immunoglobulin-like receptors (KIR) and their HLA-ligands in Italian paroxysmal nocturnal haemoglobinuria (PNH) patients
    • Cosentini E et al. 2012 Killer immunoglobulin-like receptors (KIR) and their HLA-ligands in Italian paroxysmal nocturnal haemoglobinuria (PNH) patients. Tissue Antigens 80, 322-327. (doi:10. 1111/j.1399-0039.2012.01932.x)
    • (2012) Tissue Antigens , vol.80 , pp. 322-327
    • Cosentini, E.1
  • 47
    • 84887349396 scopus 로고    scopus 로고
    • Altered natural killer cell subset homeostasis and defective chemotactic responses in paroxysmal nocturnal hemoglobinuria
    • El-Sherbiny YM, Kelly RJ, Hill A, Doody GM, Hillmen P, Cook GP. 2013 Altered natural killer cell subset homeostasis and defective chemotactic responses in paroxysmal nocturnal hemoglobinuria. Blood 122, 1887-1890. (doi:10.1182/blood-2013-06-507574)
    • (2013) Blood , vol.122 , pp. 1887-1890
    • El-Sherbiny, Y.M.1    Kelly, R.J.2    Hill, A.3    Doody, G.M.4    Hillmen, P.5    Cook, G.P.6
  • 48
    • 84923381058 scopus 로고    scopus 로고
    • Natural killer (NK) cell function in paroxysmal nocturnal hemoglobinuria: A deficiency of NK cells, but not an NK cell deficiency
    • El-Sherbiny YM, Doody GM, Kelly RJ, Hill A, Hillmen P, Cook GP. 2015 Natural killer (NK) cell function in paroxysmal nocturnal hemoglobinuria: a deficiency of NK cells, but not an NK cell deficiency. Blood 125, 1351- 1352. (doi:10.1182/blood-2014-07-591255)
    • (2015) Blood , vol.125 , pp. 1351-1352
    • El-Sherbiny, Y.M.1    Doody, G.M.2    Kelly, R.J.3    Hill, A.4    Hillmen, P.5    Cook, G.P.6
  • 49
    • 84978277874 scopus 로고    scopus 로고
    • Production and use of trimeric isoleucine zipper fusion proteins to study surface receptor ligand interactions
    • JE Coligan, BM Dunn, DW Speicher, PT Wingfield Ch. 19, unit 19.11. New York, NY: John Wiley & Sons Inc.
    • Watzl C. 2006 Production and use of trimeric isoleucine zipper fusion proteins to study surface receptor ligand interactions. In Current protocols in protein science (eds JE Coligan, BM Dunn, DW Speicher, PT Wingfield). Ch. 19, unit 19.11. New York, NY: John Wiley & Sons Inc.
    • (2006) Current Protocols in Protein Science
    • Watzl, C.1
  • 50
    • 12944303651 scopus 로고    scopus 로고
    • The use of trimeric isoleucine-zipper fusion proteins to study surface-receptor- ligand interactions in natural killer cells
    • Stark S, Flaig R-M, Sandusky M, Watzl C. 2005 The use of trimeric isoleucine-zipper fusion proteins to study surface-receptor- ligand interactions in natural killer cells. J. Immunol. Methods 296, 149-158. (doi:10.1016/j.jim.2004.11.010)
    • (2005) J. Immunol. Methods , vol.296 , pp. 149-158
    • Stark, S.1    Flaig, R.-M.2    Sandusky, M.3    Watzl, C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.