메뉴 건너뛰기




Volumn 136, Issue 3, 2016, Pages 593-602

Genome-Wide Pathway Analysis Identifies Genetic Pathways Associated with Psoriasis

(27)  Aterido, Adrià a   Julià, Antonio a   Ferrándiz, Carlos b   Puig, Lluís c   Fonseca, Eduardo d   Fernández López, Emilia e   Dauden, Esteban f   Sánchez Carazo, José Luís g   López Estebaranz, José Luís h   Moreno Ramírez, David i   Vanaclocha, Francisco j   Herrera, Enrique k   de la Cueva, Pablo l   Dand, Nick m   Palau, Núria a   Alonso, Arnald a   López Lasanta, María a   Tortosa, Raül a   García Montero, Andrés n   Codó, Laia o   more..


Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; HLA C ANTIGEN; INTERLEUKIN 12P40; ION; RETINOL;

EID: 84977766689     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1016/j.jid.2015.11.026     Document Type: Article
Times cited : (27)

References (71)
  • 1
    • 84978128360 scopus 로고    scopus 로고
    • BIOCARTA Pathways. [].
    • BIOCARTA Pathways. [ http://www.biocarta.com].
  • 2
    • 9444246402 scopus 로고    scopus 로고
    • Vitamin A status significantly alters nuclear factor-kappaB activity assessed by in vivo imaging
    • Austenaa, L.M., Carlsen, H., Ertesvag, A., et al. Vitamin A status significantly alters nuclear factor-kappaB activity assessed by in vivo imaging. Faseb J 18 (2004), 1255–1257.
    • (2004) Faseb J , vol.18 , pp. 1255-1257
    • Austenaa, L.M.1    Carlsen, H.2    Ertesvag, A.3
  • 3
    • 84876462567 scopus 로고    scopus 로고
    • Interleukin-1 family members are enhanced in psoriasis and suppressed by vitamin D and retinoic acid
    • Balato, A., Schiattarella, M., Lembo, S., et al. Interleukin-1 family members are enhanced in psoriasis and suppressed by vitamin D and retinoic acid. Arch Dermatol Res 305 (2013), 255–262.
    • (2013) Arch Dermatol Res , vol.305 , pp. 255-262
    • Balato, A.1    Schiattarella, M.2    Lembo, S.3
  • 5
    • 84923253404 scopus 로고    scopus 로고
    • Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis
    • Bowes, J., Budu-Aggrey, A., Huffmeier, U., et al. Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis. Nat Commun, 6, 2015, 6046.
    • (2015) Nat Commun , vol.6 , pp. 6046
    • Bowes, J.1    Budu-Aggrey, A.2    Huffmeier, U.3
  • 6
    • 33846608131 scopus 로고    scopus 로고
    • A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes
    • Cargill, M., Schrodi, S.J., Chang, M., et al. A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes. Am J Hum Genet 80 (2007), 273–290.
    • (2007) Am J Hum Genet , vol.80 , pp. 273-290
    • Cargill, M.1    Schrodi, S.J.2    Chang, M.3
  • 7
    • 37149029370 scopus 로고    scopus 로고
    • Calcium signaling
    • Clapham, D.E., Calcium signaling. Cell 131 (2007), 1047–1058.
    • (2007) Cell , vol.131 , pp. 1047-1058
    • Clapham, D.E.1
  • 8
    • 0036099545 scopus 로고    scopus 로고
    • Modulation of chemokine receptor expression and chemotactic responsiveness during differentiation of human naive T cells into Th1 or Th2 cells
    • Colantonio, L., Recalde, H., Sinigaglia, F., et al. Modulation of chemokine receptor expression and chemotactic responsiveness during differentiation of human naive T cells into Th1 or Th2 cells. Eur J Immunol 32 (2002), 1264–1273.
    • (2002) Eur J Immunol , vol.32 , pp. 1264-1273
    • Colantonio, L.1    Recalde, H.2    Sinigaglia, F.3
  • 9
    • 84891753483 scopus 로고    scopus 로고
    • The Reactome pathway knowledgebase
    • Croft, D., Mundo, A.F., Haw, R., et al. The Reactome pathway knowledgebase. Nucleic Acids Res 42 (2014), D472–D477.
    • (2014) Nucleic Acids Res , vol.42 , pp. D472-D477
    • Croft, D.1    Mundo, A.F.2    Haw, R.3
  • 10
    • 84911382314 scopus 로고    scopus 로고
    • Pathway analysis of cervical cancer genome-wide association study highlights the MHC region and pathways involved in response to infection
    • Chen, D., Enroth, S., Ivansson, E., et al. Pathway analysis of cervical cancer genome-wide association study highlights the MHC region and pathways involved in response to infection. Hum Mol Genet 23 (2014), 6047–6060.
    • (2014) Hum Mol Genet , vol.23 , pp. 6047-6060
    • Chen, D.1    Enroth, S.2    Ivansson, E.3
  • 11
    • 70450265471 scopus 로고    scopus 로고
    • T cell receptor signaling co-regulates multiple Golgi genes to enhance N-glycan branching
    • Chen, H.L., Li, C.F., Grigorian, A., et al. T cell receptor signaling co-regulates multiple Golgi genes to enhance N-glycan branching. J Biol Chem 284 (2009), 32454–32461.
    • (2009) J Biol Chem , vol.284 , pp. 32454-32461
    • Chen, H.L.1    Li, C.F.2    Grigorian, A.3
  • 13
    • 0035825644 scopus 로고    scopus 로고
    • Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation
    • Demetriou, M., Granovsky, M., Quaggin, S., et al. Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation. Nature 409 (2001), 733–739.
    • (2001) Nature , vol.409 , pp. 733-739
    • Demetriou, M.1    Granovsky, M.2    Quaggin, S.3
  • 14
    • 84870815661 scopus 로고    scopus 로고
    • Genome-wide association studies: inherent limitations and future challenges
    • Du, Y., Xie, J., Chang, W., et al. Genome-wide association studies: inherent limitations and future challenges. Front Med 6 (2012), 444–450.
    • (2012) Front Med , vol.6 , pp. 444-450
    • Du, Y.1    Xie, J.2    Chang, W.3
  • 15
    • 0033953110 scopus 로고    scopus 로고
    • CD69, HLA-DR and the IL-2R identify persistently activated T cells in psoriasis vulgaris lesional skin: blood and skin comparisons by flow cytometry
    • Ferenczi, K., Burack, L., Pope, M., et al. CD69, HLA-DR and the IL-2R identify persistently activated T cells in psoriasis vulgaris lesional skin: blood and skin comparisons by flow cytometry. J Autoimmun 14 (2000), 63–78.
    • (2000) J Autoimmun , vol.14 , pp. 63-78
    • Ferenczi, K.1    Burack, L.2    Pope, M.3
  • 16
    • 1842413033 scopus 로고    scopus 로고
    • Cutaneous lymphocyte antigen is a specialized form of PSGL-1 expressed on skin-homing T cells
    • Fuhlbrigge, R.C., Kieffer, J.D., Armerding, D., et al. Cutaneous lymphocyte antigen is a specialized form of PSGL-1 expressed on skin-homing T cells. Nature 389 (1997), 978–981.
    • (1997) Nature , vol.389 , pp. 978-981
    • Fuhlbrigge, R.C.1    Kieffer, J.D.2    Armerding, D.3
  • 17
    • 84855925920 scopus 로고    scopus 로고
    • Rare and common variants: twenty arguments
    • Gibson, G., Rare and common variants: twenty arguments. Nat Rev Genet 13 (2012), 135–145.
    • (2012) Nat Rev Genet , vol.13 , pp. 135-145
    • Gibson, G.1
  • 18
    • 47249142778 scopus 로고    scopus 로고
    • Revealing the architecture of gene regulation: the promise of eQTL studies
    • Gilad, Y., Rifkin, S.A., Pritchard, J.K., Revealing the architecture of gene regulation: the promise of eQTL studies. Trends Genet 24 (2008), 408–415.
    • (2008) Trends Genet , vol.24 , pp. 408-415
    • Gilad, Y.1    Rifkin, S.A.2    Pritchard, J.K.3
  • 19
    • 84916623158 scopus 로고    scopus 로고
    • Measuring missing heritability: inferring the contribution of common variants
    • Golan, D., Lander, E.S., Rosset, S., Measuring missing heritability: inferring the contribution of common variants. Proc Natl Acad Sci USA 111 (2014), E5272–E5281.
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. E5272-E5281
    • Golan, D.1    Lander, E.S.2    Rosset, S.3
  • 20
    • 84873567016 scopus 로고    scopus 로고
    • NF-kappaB: an essential transcription factor in psoriasis
    • Goldminz, A.M., Au, S.C., Kim, N., et al. NF-kappaB: an essential transcription factor in psoriasis. J Dermatol Sci 69 (2013), 89–94.
    • (2013) J Dermatol Sci , vol.69 , pp. 89-94
    • Goldminz, A.M.1    Au, S.C.2    Kim, N.3
  • 21
    • 34548046221 scopus 로고    scopus 로고
    • Mammalian N-glycan branching protects against innate immune self-recognition and inflammation in autoimmune disease pathogenesis
    • Green, R.S., Stone, E.L., Tenno, M., et al. Mammalian N-glycan branching protects against innate immune self-recognition and inflammation in autoimmune disease pathogenesis. Immunity 27 (2007), 308–320.
    • (2007) Immunity , vol.27 , pp. 308-320
    • Green, R.S.1    Stone, E.L.2    Tenno, M.3
  • 22
    • 84875369241 scopus 로고    scopus 로고
    • Mgat5 deficiency in T cells and experimental autoimmune encephalomyelitis
    • Grigorian, A., Demetriou, M., Mgat5 deficiency in T cells and experimental autoimmune encephalomyelitis. ISRN Neurol, 2011, 374314.
    • (2011) ISRN Neurol , pp. 374314
    • Grigorian, A.1    Demetriou, M.2
  • 24
    • 80053478943 scopus 로고    scopus 로고
    • Comparisons of seven algorithms for pathway analysis using the WTCCC Crohn's Disease dataset
    • Gui, H., Li, M., Sham, P.C., et al. Comparisons of seven algorithms for pathway analysis using the WTCCC Crohn's Disease dataset. BMC Res Notes, 4, 2011, 386.
    • (2011) BMC Res Notes , vol.4 , pp. 386
    • Gui, H.1    Li, M.2    Sham, P.C.3
  • 25
    • 16344381521 scopus 로고    scopus 로고
    • Comparative genomics of centrality and essentiality in three eukaryotic protein-interaction networks
    • Hahn, M.W., Kern, A.D., Comparative genomics of centrality and essentiality in three eukaryotic protein-interaction networks. Mol Biol Evol 22 (2005), 803–806.
    • (2005) Mol Biol Evol , vol.22 , pp. 803-806
    • Hahn, M.W.1    Kern, A.D.2
  • 26
    • 84885446960 scopus 로고    scopus 로고
    • LAT1 is a critical transporter of essential amino acids for immune reactions in activated human T cells
    • Hayashi, K., Jutabha, P., Endou, H., et al. LAT1 is a critical transporter of essential amino acids for immune reactions in activated human T cells. J Immunol 191 (2013), 4080–4085.
    • (2013) J Immunol , vol.191 , pp. 4080-4085
    • Hayashi, K.1    Jutabha, P.2    Endou, H.3
  • 27
    • 0025066941 scopus 로고
    • More powerful procedures for multiple significance testing
    • Hochberg, Y., Benjamini, Y., More powerful procedures for multiple significance testing. Stat Med 9 (1990), 811–818.
    • (1990) Stat Med , vol.9 , pp. 811-818
    • Hochberg, Y.1    Benjamini, Y.2
  • 28
    • 79953097995 scopus 로고    scopus 로고
    • The autoantigen Pso p27: a post-translational modification of SCCA molecules
    • Iversen, O.J., Lysvand, H., Hagen, L., The autoantigen Pso p27: a post-translational modification of SCCA molecules. Autoimmunity 44 (2011), 229–234.
    • (2011) Autoimmunity , vol.44 , pp. 229-234
    • Iversen, O.J.1    Lysvand, H.2    Hagen, L.3
  • 29
    • 39749097945 scopus 로고    scopus 로고
    • Characterization of cationic amino acid transporters (hCATs) 1 and 2 in human skin
    • Jaeger, K., Paulsen, F., Wohlrab, J., Characterization of cationic amino acid transporters (hCATs) 1 and 2 in human skin. Histochem Cell Biol 129 (2008), 321–329.
    • (2008) Histochem Cell Biol , vol.129 , pp. 321-329
    • Jaeger, K.1    Paulsen, F.2    Wohlrab, J.3
  • 30
    • 78650353878 scopus 로고    scopus 로고
    • Accounting for multiple comparisons in a genome-wide association study (GWAS)
    • Johnson, R.C., Nelson, G.W., Troyer, J.L., et al. Accounting for multiple comparisons in a genome-wide association study (GWAS). BMC Genomics, 11, 2010, 724.
    • (2010) BMC Genomics , vol.11 , pp. 724
    • Johnson, R.C.1    Nelson, G.W.2    Troyer, J.L.3
  • 31
    • 27744469130 scopus 로고    scopus 로고
    • High-betweenness proteins in the yeast protein interaction network
    • Joy, M.P., Brock, A., Ingber, D.E., et al. High-betweenness proteins in the yeast protein interaction network. J Biomed Biotechnol 2005 (2005), 96–103.
    • (2005) J Biomed Biotechnol , vol.2005 , pp. 96-103
    • Joy, M.P.1    Brock, A.2    Ingber, D.E.3
  • 32
    • 0033982936 scopus 로고    scopus 로고
    • KEGG: Kyoto Encyclopedia of Genes and Genomes
    • Kanehisa, M., Goto, S., KEGG: Kyoto Encyclopedia of Genes and Genomes. Nucleic Acids Res 28 (2000), 27–30.
    • (2000) Nucleic Acids Res , vol.28 , pp. 27-30
    • Kanehisa, M.1    Goto, S.2
  • 33
    • 84875144768 scopus 로고    scopus 로고
    • The SLC8 gene family of sodium-calcium exchangers (NCX)—structure, function, and regulation in health and disease
    • Khananshvili, D., The SLC8 gene family of sodium-calcium exchangers (NCX)—structure, function, and regulation in health and disease. Mol Aspects Med 34 (2013), 220–235.
    • (2013) Mol Aspects Med , vol.34 , pp. 220-235
    • Khananshvili, D.1
  • 34
    • 84911419194 scopus 로고    scopus 로고
    • Pathway-based analysis of GWAs data identifies association of sex determination genes with susceptibility to testicular germ cell tumors
    • Koster, R., Mitra, N., D'Andrea, K., et al. Pathway-based analysis of GWAs data identifies association of sex determination genes with susceptibility to testicular germ cell tumors. Hum Mol Genet 23 (2014), 6061–6068.
    • (2014) Hum Mol Genet , vol.23 , pp. 6061-6068
    • Koster, R.1    Mitra, N.2    D'Andrea, K.3
  • 35
    • 79960112716 scopus 로고    scopus 로고
    • MADAM: an open source meta-analysis toolbox for R and Bioconductor
    • Kugler, K.G., Mueller, L.A., Graber, A., MADAM: an open source meta-analysis toolbox for R and Bioconductor. Source Code Biol Med, 5, 2010, 3.
    • (2010) Source Code Biol Med , vol.5 , pp. 3
    • Kugler, K.G.1    Mueller, L.A.2    Graber, A.3
  • 36
    • 84893096826 scopus 로고    scopus 로고
    • Regulation of transport across cell membranes by the serum- and glucocorticoid-inducible kinase SGK1
    • Lang, F., Stournaras, C., Alesutan, I., Regulation of transport across cell membranes by the serum- and glucocorticoid-inducible kinase SGK1. Mol Membr Biol 31 (2014), 29–36.
    • (2014) Mol Membr Biol , vol.31 , pp. 29-36
    • Lang, F.1    Stournaras, C.2    Alesutan, I.3
  • 37
    • 10444237214 scopus 로고    scopus 로고
    • ATM signaling and genomic stability in response to DNA damage
    • Lavin, M.F., Birrell, G., Chen, P., et al. ATM signaling and genomic stability in response to DNA damage. Mutat Res 569 (2005), 123–132.
    • (2005) Mutat Res , vol.569 , pp. 123-132
    • Lavin, M.F.1    Birrell, G.2    Chen, P.3
  • 38
    • 20544451475 scopus 로고    scopus 로고
    • Differential expression of phosphorylated NF-kappaB/RelA in normal and psoriatic epidermis and downregulation of NF-kappaB in response to treatment with etanercept
    • Lizzul, P.F., Aphale, A., Malaviya, R., et al. Differential expression of phosphorylated NF-kappaB/RelA in normal and psoriatic epidermis and downregulation of NF-kappaB in response to treatment with etanercept. J Invest Dermatol 124 (2005), 1275–1283.
    • (2005) J Invest Dermatol , vol.124 , pp. 1275-1283
    • Lizzul, P.F.1    Aphale, A.2    Malaviya, R.3
  • 39
    • 77954407332 scopus 로고    scopus 로고
    • Genomewide association studies and assessment of the risk of disease
    • Manolio, T.A., Genomewide association studies and assessment of the risk of disease. N Engl J Med 363 (2010), 166–176.
    • (2010) N Engl J Med , vol.363 , pp. 166-176
    • Manolio, T.A.1
  • 40
    • 84884950833 scopus 로고    scopus 로고
    • BLUEPRINT: mapping human blood cell epigenomes
    • Martens, J.H., Stunnenberg, H.G., BLUEPRINT: mapping human blood cell epigenomes. Haematologica 98 (2013), 1487–1489.
    • (2013) Haematologica , vol.98 , pp. 1487-1489
    • Martens, J.H.1    Stunnenberg, H.G.2
  • 41
    • 79958728985 scopus 로고    scopus 로고
    • Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis
    • Mkhikian, H., Grigorian, A., Li, C.F., et al. Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis. Nat Commun, 2, 2011, 334.
    • (2011) Nat Commun , vol.2 , pp. 334
    • Mkhikian, H.1    Grigorian, A.2    Li, C.F.3
  • 42
    • 42149140747 scopus 로고    scopus 로고
    • Polymorphisms of the IL12B and IL23R genes are associated with psoriasis
    • Nair, R.P., Ruether, A., Stuart, P.E., et al. Polymorphisms of the IL12B and IL23R genes are associated with psoriasis. J Invest Dermatol 128 (2008), 1653–1661.
    • (2008) J Invest Dermatol , vol.128 , pp. 1653-1661
    • Nair, R.P.1    Ruether, A.2    Stuart, P.E.3
  • 43
    • 33646049742 scopus 로고    scopus 로고
    • Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene
    • Nair, R.P., Stuart, P.E., Nistor, I., et al. Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene. Am J Hum Genet 78 (2006), 827–851.
    • (2006) Am J Hum Genet , vol.78 , pp. 827-851
    • Nair, R.P.1    Stuart, P.E.2    Nistor, I.3
  • 45
    • 77954133026 scopus 로고    scopus 로고
    • Estimation of effect size distribution from genome-wide association studies and implications for future discoveries
    • Park, J.H., Wacholder, S., Gail, M.H., et al. Estimation of effect size distribution from genome-wide association studies and implications for future discoveries. Nat Genet 42 (2010), 570–575.
    • (2010) Nat Genet , vol.42 , pp. 570-575
    • Park, J.H.1    Wacholder, S.2    Gail, M.H.3
  • 46
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: a tool set for whole-genome association and population-based linkage analyses
    • Purcell, S., Neale, B., Todd-Brown, K., et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 81 (2007), 559–575.
    • (2007) Am J Hum Genet , vol.81 , pp. 559-575
    • Purcell, S.1    Neale, B.2    Todd-Brown, K.3
  • 47
    • 84862499271 scopus 로고    scopus 로고
    • Pathway analysis of genomic data: concepts, methods, and prospects for future development
    • Ramanan, V.K., Shen, L., Moore, J.H., et al. Pathway analysis of genomic data: concepts, methods, and prospects for future development. Trends Genet 28 (2012), 323–332.
    • (2012) Trends Genet , vol.28 , pp. 323-332
    • Ramanan, V.K.1    Shen, L.2    Moore, J.H.3
  • 48
    • 78651338017 scopus 로고    scopus 로고
    • ENCODE whole-genome data in the UCSC genome browser (2011 update)
    • Raney, B.J., Cline, M.S., Rosenbloom, K.R., et al. ENCODE whole-genome data in the UCSC genome browser (2011 update). Nucleic Acids Res 39 (2011), D871–D875.
    • (2011) Nucleic Acids Res , vol.39 , pp. D871-D875
    • Raney, B.J.1    Cline, M.S.2    Rosenbloom, K.R.3
  • 49
    • 33747884339 scopus 로고    scopus 로고
    • DNA damage-induced cell death by apoptosis
    • Roos, W.P., Kaina, B., DNA damage-induced cell death by apoptosis. Trends Mol Med 12 (2006), 440–450.
    • (2006) Trends Mol Med , vol.12 , pp. 440-450
    • Roos, W.P.1    Kaina, B.2
  • 50
    • 0035937526 scopus 로고    scopus 로고
    • Glycosylation and the immune system
    • Rudd, P.M., Elliott, T., Cresswell, P., et al. Glycosylation and the immune system. Science 291 (2001), 2370–2376.
    • (2001) Science , vol.291 , pp. 2370-2376
    • Rudd, P.M.1    Elliott, T.2    Cresswell, P.3
  • 51
    • 84866112912 scopus 로고    scopus 로고
    • Roles for major histocompatibility complex glycosylation in immune function
    • Ryan, S.O., Cobb, B.A., Roles for major histocompatibility complex glycosylation in immune function. Semin Immunopathol 34 (2012), 425–441.
    • (2012) Semin Immunopathol , vol.34 , pp. 425-441
    • Ryan, S.O.1    Cobb, B.A.2
  • 52
    • 78049347495 scopus 로고    scopus 로고
    • A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1
    • Strange, A., Capon, F., Spencer, C.C., et al. A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat Genet 42 (2010), 985–990.
    • (2010) Nat Genet , vol.42 , pp. 985-990
    • Strange, A.1    Capon, F.2    Spencer, C.C.3
  • 53
    • 84885960571 scopus 로고    scopus 로고
    • CXCR4 negatively regulates keratinocyte proliferation in IL-23-mediated psoriasiform dermatitis
    • Takekoshi, T., Wu, X., Mitsui, H., et al. CXCR4 negatively regulates keratinocyte proliferation in IL-23-mediated psoriasiform dermatitis. J Invest Dermatol 133 (2013), 2530–2537.
    • (2013) J Invest Dermatol , vol.133 , pp. 2530-2537
    • Takekoshi, T.1    Wu, X.2    Mitsui, H.3
  • 54
    • 84927747665 scopus 로고    scopus 로고
    • Graphical algorithm for integration of genetic and biological data: proof of principle using psoriasis as a model
    • Tsoi, L.C., Elder, J.T., Abecasis, G.R., Graphical algorithm for integration of genetic and biological data: proof of principle using psoriasis as a model. Bioinformatics 31 (2015), 1243–1249.
    • (2015) Bioinformatics , vol.31 , pp. 1243-1249
    • Tsoi, L.C.1    Elder, J.T.2    Abecasis, G.R.3
  • 55
    • 84929157252 scopus 로고    scopus 로고
    • Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci
    • Tsoi, L.C., Spain, S.L., Ellinghaus, E., et al. Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci. Nat Commun, 6, 2015, 7001.
    • (2015) Nat Commun , vol.6 , pp. 7001
    • Tsoi, L.C.1    Spain, S.L.2    Ellinghaus, E.3
  • 56
    • 84870512735 scopus 로고    scopus 로고
    • Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity
    • Tsoi, L.C., Spain, S.L., Knight, J., et al. Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. Nat Genet 44 (2012), 1341–1348.
    • (2012) Nat Genet , vol.44 , pp. 1341-1348
    • Tsoi, L.C.1    Spain, S.L.2    Knight, J.3
  • 57
    • 61449176345 scopus 로고    scopus 로고
    • NF-kappaB links keratinocytes and lymphocytes in the pathogenesis of psoriasis
    • Tsuruta, D., NF-kappaB links keratinocytes and lymphocytes in the pathogenesis of psoriasis. Recent Pat Inflamm Allergy Drug Discov 3 (2009), 40–48.
    • (2009) Recent Pat Inflamm Allergy Drug Discov , vol.3 , pp. 40-48
    • Tsuruta, D.1
  • 58
    • 65449152586 scopus 로고    scopus 로고
    • Identifying hubs in protein interaction networks
    • Vallabhajosyula, R.R., Chakravarti, D., Lutfeali, S., et al. Identifying hubs in protein interaction networks. PLoS One, 4, 2009, e5344.
    • (2009) PLoS One , vol.4 , pp. e5344
    • Vallabhajosyula, R.R.1    Chakravarti, D.2    Lutfeali, S.3
  • 59
    • 57849148942 scopus 로고    scopus 로고
    • Calcium signaling in immune cells
    • Vig, M., Kinet, J.P., Calcium signaling in immune cells. Nat Immunol 10 (2009), 21–27.
    • (2009) Nat Immunol , vol.10 , pp. 21-27
    • Vig, M.1    Kinet, J.P.2
  • 60
    • 0029982537 scopus 로고    scopus 로고
    • Genetic analysis of autoimmune disease
    • Vyse, T.J., Todd, J.A., Genetic analysis of autoimmune disease. Cell 85 (1996), 311–318.
    • (1996) Cell , vol.85 , pp. 311-318
    • Vyse, T.J.1    Todd, J.A.2
  • 61
    • 78549251736 scopus 로고    scopus 로고
    • Analysing biological pathways in genome-wide association studies
    • Wang, K., Li, M., Hakonarson, H., Analysing biological pathways in genome-wide association studies. Nat Rev Genet 11 (2010), 843–854.
    • (2010) Nat Rev Genet , vol.11 , pp. 843-854
    • Wang, K.1    Li, M.2    Hakonarson, H.3
  • 62
    • 80955181032 scopus 로고    scopus 로고
    • Keratinocyte apoptosis in epidermal remodeling and clearance of psoriasis induced by UV radiation
    • Weatherhead, S.C., Farr, P.M., Jamieson, D., et al. Keratinocyte apoptosis in epidermal remodeling and clearance of psoriasis induced by UV radiation. J Invest Dermatol 131 (2011), 1916–1926.
    • (2011) J Invest Dermatol , vol.131 , pp. 1916-1926
    • Weatherhead, S.C.1    Farr, P.M.2    Jamieson, D.3
  • 63
    • 84859757141 scopus 로고    scopus 로고
    • Abnormal epidermal barrier in the pathogenesis of psoriasis
    • Wolf, R., Orion, E., Ruocco, E., et al. Abnormal epidermal barrier in the pathogenesis of psoriasis. Clin Dermatol 30 (2012), 323–328.
    • (2012) Clin Dermatol , vol.30 , pp. 323-328
    • Wolf, R.1    Orion, E.2    Ruocco, E.3
  • 64
    • 77953121307 scopus 로고    scopus 로고
    • Powerful SNP-set analysis for case-control genome-wide association studies
    • Wu, M.C., Kraft, P., Epstein, M.P., et al. Powerful SNP-set analysis for case-control genome-wide association studies. Am J Hum Genet 86 (2010), 929–942.
    • (2010) Am J Hum Genet , vol.86 , pp. 929-942
    • Wu, M.C.1    Kraft, P.2    Epstein, M.P.3
  • 65
    • 84928577617 scopus 로고    scopus 로고
    • Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility
    • Yin, X., Low, H.Q., Wang, L., et al. Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility. Nat Commun, 6, 2015, 6916.
    • (2015) Nat Commun , vol.6 , pp. 6916
    • Yin, X.1    Low, H.Q.2    Wang, L.3
  • 66
    • 84893161815 scopus 로고    scopus 로고
    • Common variants explain a large fraction of the variability in the liability to psoriasis in a Han Chinese population
    • Yin, X., Wineinger, N.E., Cheng, H., et al. Common variants explain a large fraction of the variability in the liability to psoriasis in a Han Chinese population. BMC Genomics, 15, 2014, 87.
    • (2014) BMC Genomics , vol.15 , pp. 87
    • Yin, X.1    Wineinger, N.E.2    Cheng, H.3
  • 67
    • 84898863120 scopus 로고    scopus 로고
    • An important role of the SDF-1/CXCR4 axis in chronic skin inflammation
    • Zgraggen, S., Huggenberger, R., Kerl, K., et al. An important role of the SDF-1/CXCR4 axis in chronic skin inflammation. PLoS One, 9, 2014, e93665.
    • (2014) PLoS One , vol.9 , pp. e93665
    • Zgraggen, S.1    Huggenberger, R.2    Kerl, K.3
  • 68
    • 77954246243 scopus 로고    scopus 로고
    • i-GSEA4GWAS: a web server for identification of pathways/gene sets associated with traits by applying an improved gene set enrichment analysis to genome-wide association study
    • Zhang, K., Cui, S., Chang, S., et al. i-GSEA4GWAS: a web server for identification of pathways/gene sets associated with traits by applying an improved gene set enrichment analysis to genome-wide association study. Nucleic Acids Res 38 (2010), W90–W95.
    • (2010) Nucleic Acids Res , vol.38 , pp. W90-W95
    • Zhang, K.1    Cui, S.2    Chang, S.3
  • 69
    • 77950339092 scopus 로고    scopus 로고
    • Integrating pathway analysis and genetics of gene expression for genome-wide association studies
    • Zhong, H., Yang, X., Kaplan, L.M., et al. Integrating pathway analysis and genetics of gene expression for genome-wide association studies. Am J Hum Genet 86 (2010), 581–591.
    • (2010) Am J Hum Genet , vol.86 , pp. 581-591
    • Zhong, H.1    Yang, X.2    Kaplan, L.M.3
  • 70
    • 84879691304 scopus 로고    scopus 로고
    • Meta-analysis of IL12B polymorphisms (rs3212227, rs6887695) with psoriasis and psoriatic arthritis
    • Zhu, K.J., Zhu, C.Y., Shi, G., et al. Meta-analysis of IL12B polymorphisms (rs3212227, rs6887695) with psoriasis and psoriatic arthritis. Rheumatol Int 33 (2013), 1785–1790.
    • (2013) Rheumatol Int , vol.33 , pp. 1785-1790
    • Zhu, K.J.1    Zhu, C.Y.2    Shi, G.3
  • 71
    • 84927637587 scopus 로고    scopus 로고
    • Whole-exome SNP array identifies 15 new susceptibility loci for psoriasis
    • Zuo, X., Sun, L., Yin, X., et al. Whole-exome SNP array identifies 15 new susceptibility loci for psoriasis. Nat Commun, 6, 2015, 6793.
    • (2015) Nat Commun , vol.6 , pp. 6793
    • Zuo, X.1    Sun, L.2    Yin, X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.