KG-135 inhibits COX-2 expression by blocking the activation of JNK and AP-1 in phorbol ester-stimulated human breast epithelial cells

Annals of the New York Academy of Sciences

Volumn 1095, Issue , 2007, Pages 545-553

  Park, Sin Aye ^a   Kim, Eun Hee ^a   Na, Hye Kyung ^a   Surh, Young Joon ^a  

^a Seoul National University   (South Korea)

Author keywords

Activator protein 1; Cyclooxygenase 2; JNK AP 1; KG 135; MCF 10A cells; TPA

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; KG 135; PHORBOL 13 ACETATE 12 MYRISTATE; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; CYCLOOXYGENASE 2 INHIBITOR; GINSENOSIDE; PROTEIN KINASE INHIBITOR;

ANTIINFLAMMATORY ACTIVITY; BREAST EPITHELIUM; CELL LINE; CELL STIMULATION; CHEMOPROPHYLAXIS; CONFERENCE PAPER; CONTROLLED STUDY; DNA BINDING; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; EPITHELIUM CELL; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TUMOR PROMOTION; UPREGULATION; ARTICLE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; FEMALE; MAMMARY GLAND; METABOLISM;

PANAX GINSENG;

CELL LINE, TRANSFORMED; CYCLOOXYGENASE 2 INHIBITORS; ENZYME ACTIVATION; EPITHELIAL CELLS; FEMALE; GINSENOSIDES; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAMMARY GLANDS, HUMAN; PROTEIN KINASE INHIBITORS; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION FACTOR AP-1;

EID: 34247868831     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1397.059     Document Type: Conference Paper

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