메뉴 건너뛰기




Volumn 14, Issue 3, 2018, Pages 617-624

Lutein prevents osteoarthritis through Nrf2 activation and downregulation of inflammation

Author keywords

Inflammation; Lutein; Osteoarthritis; Oxidative stress; Reactive oxygen species

Indexed keywords

CASPASE 3; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPID PEROXIDE; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR; XANTHOPHYLL;

EID: 84977278335     PISSN: 17341922     EISSN: 18969151     Source Type: Journal    
DOI: 10.5114/aoms.2016.59871     Document Type: Article
Times cited : (69)

References (40)
  • 2
    • 0032211876 scopus 로고    scopus 로고
    • Pathophysiology of osteoarthritis
    • Martel-Pelletier J. Pathophysiology of osteoarthritis. Osteoarthr Cartilage 1998; 6: 374-6.
    • (1998) Osteoarthr Cartilage , vol.6 , pp. 374-376
    • Martel-Pelletier, J.1
  • 4
    • 84928411648 scopus 로고    scopus 로고
    • Quercetin protects against lipopolysaccharide-induced acute lung injury in rats through suppression of inflammation and oxidative stress
    • Huang R, Zhong T, Wu H. Quercetin protects against lipopolysaccharide-induced acute lung injury in rats through suppression of inflammation and oxidative stress. Arch Med Sci 2015; 11: 427-32.
    • (2015) Arch Med Sci , vol.11 , pp. 427-432
    • Huang, R.1    Zhong, T.2    Wu, H.3
  • 5
    • 84944029393 scopus 로고    scopus 로고
    • Antioxidant and antiapoptotic effects of darbepoetin-alpha against traumatic brain injury in rats
    • Kertmen H, Gürer B, Yilmaz ER, et al. Antioxidant and antiapoptotic effects of darbepoetin-alpha against traumatic brain injury in rats. Arch Med Sci 2015; 11: 1119-28.
    • (2015) Arch Med Sci , vol.11 , pp. 1119-1128
    • Kertmen, H.1    Gürer, B.2    Yilmaz, E.R.3
  • 7
    • 0031658490 scopus 로고    scopus 로고
    • Fruits and vegetables that are sources for lutein and zeaxanthin: The macular pigment in human eyes
    • Sommerburg O, Keunen JE, Bird AC, van Kuijk FJ. Fruits and vegetables that are sources for lutein and zeaxanthin: The macular pigment in human eyes. Br J Ophthalmol 1998; 82: 907-10.
    • (1998) Br J Ophthalmol , vol.82 , pp. 907-910
    • Sommerburg, O.1    Keunen, J.E.2    Bird, A.C.3    Van Kuijk, F.J.4
  • 8
    • 79961102139 scopus 로고    scopus 로고
    • A lutein-enriched diet prevents cholesterol accumulation and decreases oxidized LDL and inflammatory cytokines in the aorta of Guinea pigs
    • Kim JE, Leite JO, DeOgburn R, Smyth JA, Clark RM, Fernandez ML. A lutein-enriched diet prevents cholesterol accumulation and decreases oxidized LDL and inflammatory cytokines in the aorta of guinea pigs. J Nutr 2011; 141: 1458-63.
    • (2011) J Nutr , vol.141 , pp. 1458-1463
    • Kim, J.E.1    Leite, J.O.2    DeOgburn, R.3    Smyth, J.A.4    Clark, R.M.5    Fernandez, M.L.6
  • 9
    • 54949129134 scopus 로고    scopus 로고
    • The non-provitamin A carotenoid lutein inhibits NF-kappaB-dependent gene expression through redox-based regulation of the phosphatidylinositol 3-kinase/PTEN/Akt and NF-kappaB-inducing kinase pathways: Role of H(2)O(2) in NF-kappaB activation
    • Kim JH, Na HJ, Kim CK, et al. The non-provitamin A carotenoid lutein inhibits NF-kappaB-dependent gene expression through redox-based regulation of the phosphatidylinositol 3-kinase/PTEN/Akt and NF-kappaB-inducing kinase pathways: Role of H(2)O(2) in NF-kappaB activation. Free Radic Biol Med 2008; 45: 885-96.
    • (2008) Free Radic Biol Med , vol.45 , pp. 885-896
    • Kim, J.H.1    Na, H.J.2    Kim, C.K.3
  • 10
    • 84875644612 scopus 로고    scopus 로고
    • Radical scavenging activitybased and AP-1-targeted anti-inflammatory effects of lutein in macrophage-like and skin keratinocytic cells
    • Oh J, Kim JH, Park JG, et al. Radical scavenging activitybased and AP-1-targeted anti-inflammatory effects of lutein in macrophage-like and skin keratinocytic cells. Mediators Inflamm 2013; 2013: 787042.
    • (2013) Mediators Inflamm , vol.2013 , pp. 787042
    • Oh, J.1    Kim, J.H.2    Park, J.G.3
  • 11
    • 84916618574 scopus 로고    scopus 로고
    • Lutein protects against ischemia/reperfusion injury in rat kidneys
    • Liu ZG, Qi ZC, Liu WL, Wang WZ. Lutein protects against ischemia/reperfusion injury in rat kidneys. Mol Med Rep 2015; 11: 2179-84.
    • (2015) Mol Med Rep , vol.11 , pp. 2179-2184
    • Liu, Z.G.1    Qi, Z.C.2    Liu, W.L.3    Wang, W.Z.4
  • 12
    • 79952534671 scopus 로고    scopus 로고
    • Protective effect of lutein after ischemia-reperfusion in the small intestine
    • Sato Y, Kobayashi M, Itagaki S, et al. Protective effect of lutein after ischemia-reperfusion in the small intestine. Food Chem 2011; 127: 893-8.
    • (2011) Food Chem , vol.127 , pp. 893-898
    • Sato, Y.1    Kobayashi, M.2    Itagaki, S.3
  • 13
    • 77954904046 scopus 로고    scopus 로고
    • Carotenoid lutein protects rats from paracetamol- carbon tetrachloride-and ethanol-induced hepatic damage
    • Sindhu ER, Firdous AP, Preethi KC, Kuttan R. Carotenoid lutein protects rats from paracetamol- carbon tetrachloride-and ethanol-induced hepatic damage. J Pharm Pharmacol 2010; 62: 1054-60.
    • (2010) J Pharm Pharmacol , vol.62 , pp. 1054-1060
    • Sindhu, E.R.1    Firdous, A.P.2    Preethi, K.C.3    Kuttan, R.4
  • 14
    • 84872766500 scopus 로고    scopus 로고
    • Monosodium iodoacetate induces apoptosis via the mitochondrial pathway involving ROS production and caspase activation in rat chondrocytes in vitro
    • Jiang L, Li L, Geng C, et al. Monosodium iodoacetate induces apoptosis via the mitochondrial pathway involving ROS production and caspase activation in rat chondrocytes in vitro. J Orthop Res 2013; 31: 364-9.
    • (2013) J Orthop Res , vol.31 , pp. 364-369
    • Jiang, L.1    Li, L.2    Geng, C.3
  • 15
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 1983; 65: 55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 16
    • 0027249757 scopus 로고
    • Evaluation of 27-dichlorofluorescein and dihydrorhodamine 123 a fluorescent probes for intracellular H2O2 in cultured endothelial cells
    • Royall JA, Ischiropoulos H. Evaluation of 27-dichlorofluorescein and dihydrorhodamine 123 a fluorescent probes for intracellular H2O2 in cultured endothelial cells. Arch Biochem Biophy 1993; 302: 348-55.
    • (1993) Arch Biochem Biophy , vol.302 , pp. 348-355
    • Royall, J.A.1    Ischiropoulos, H.2
  • 17
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbitturic acid reaction
    • Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbitturic acid reaction. Anal Biochem 1979; 95: 351-8.
    • (1979) Anal Biochem , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 18
    • 0023952554 scopus 로고
    • A simple method for clinical assay of superoxide dismutase
    • Sun Y, Oberley LW, Ying L. A simple method for clinical assay of superoxide dismutase. Clin Chem 1988; 34: 497-500.
    • (1988) Clin Chem , vol.34 , pp. 497-500
    • Sun, Y.1    Oberley, L.W.2    Ying, L.3
  • 19
    • 0000524408 scopus 로고
    • Catalase in vitro
    • Aebi H. Catalase in vitro. Methods Enzymol 1984; 105: 1-126.
    • (1984) Methods Enzymol , vol.105 , pp. 1-126
    • Aebi, H.1
  • 20
    • 0016275313 scopus 로고
    • Glutathione S-transferases. The first enzymatic step in mercapturic acid formation
    • Habig WH, Pabst MJ, Jakoby WB. Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J Biol Chem 1974; 249: 7130-9.
    • (1974) J Biol Chem , vol.249 , pp. 7130-7139
    • Habig, W.H.1    Pabst, M.J.2    Jakoby, W.B.3
  • 21
    • 0014108436 scopus 로고
    • Studies on the quantitative and qualitative characterisation of erythrocyte glutathione peroxidase
    • Paglia DE, Valentine WN. Studies on the quantitative and qualitative characterisation of erythrocyte glutathione peroxidase. J Lab Clin Med 1967; 70: 158-69.
    • (1967) J Lab Clin Med , vol.70 , pp. 158-169
    • Paglia, D.E.1    Valentine, W.N.2
  • 23
    • 77951587035 scopus 로고    scopus 로고
    • Therapeutic effect of the saponin fraction from Clematis chinensis Osbeck roots on osteoarthritis induced by monosodium iodoacetate through protecting articular cartilage
    • Wu WJ, Xu XX, Dai Y, Xia L. Therapeutic effect of the saponin fraction from Clematis chinensis Osbeck roots on osteoarthritis induced by monosodium iodoacetate through protecting articular cartilage. Phytother Res 2010; 24: 538-46.
    • (2010) Phytother Res , vol.24 , pp. 538-546
    • Wu, W.J.1    Xu, X.X.2    Dai, Y.3    Xia, L.4
  • 25
    • 0030612396 scopus 로고    scopus 로고
    • Detection of superoxide and NADPH oxidase in porcine articular chondrocytes
    • Hiran TS, Moulton PJ, Hancock JT. Detection of superoxide and NADPH oxidase in porcine articular chondrocytes. Free Radic Biol Med 1997; 23: 736-43.
    • (1997) Free Radic Biol Med , vol.23 , pp. 736-743
    • Hiran, T.S.1    Moulton, P.J.2    Hancock, J.T.3
  • 26
    • 13144261687 scopus 로고    scopus 로고
    • Chondrocyte apoptosis in development aging and disease
    • Horton WE, Feng L, Adans C. Chondrocyte apoptosis in development aging and disease. Matrix Biol 1998; 17: 107-15.
    • (1998) Matrix Biol , vol.17 , pp. 107-115
    • Horton, W.E.1    Feng, L.2    Adans, C.3
  • 27
    • 22644441306 scopus 로고    scopus 로고
    • Oxygen and reactive oxygen species in cartilage degradation: Friends or foes?
    • Henrotin Y, Kurz B, Aigner T. Oxygen and reactive oxygen species in cartilage degradation: Friends or foes? Osteoarthritis Cartilage 2005; 13: 643-54.
    • (2005) Osteoarthritis Cartilage , vol.13 , pp. 643-654
    • Henrotin, Y.1    Kurz, B.2    Aigner, T.3
  • 28
    • 77955011508 scopus 로고    scopus 로고
    • Antioxidant activity of carotenoid lutein in vitro and in vivo
    • Sindhu ER, Preethi KC, Kuttan R. Antioxidant activity of carotenoid lutein in vitro and in vivo. Indian J Exp Biol 2010; 48: 843-8.
    • (2010) Indian J Exp Biol , vol.48 , pp. 843-848
    • Sindhu, E.R.1    Preethi, K.C.2    Kuttan, R.3
  • 29
    • 80054967620 scopus 로고    scopus 로고
    • Antioxidant properties of lutein contribute to the protection against lipopolysaccharide-induced uveitis in mice
    • He RR, Tsoi B, Lan F, Yao N, Yao XS, Kurihara H. Antioxidant properties of lutein contribute to the protection against lipopolysaccharide-induced uveitis in mice. Chin Med 2011; 6: 38.
    • (2011) Chin Med , vol.6 , pp. 38
    • He, R.R.1    Tsoi, B.2    Lan, F.3    Yao, N.4    Yao, X.S.5    Kurihara, H.6
  • 30
    • 84942824931 scopus 로고    scopus 로고
    • Lutein suppresses inflammatory responses through Nrf2 activation and NF-kappaB inactivation in lipopolysaccharide-stimulated BV-2 microglia
    • Wu W, Li Y, Wu Y, Zhang Y, Wang Z, Liu X. Lutein suppresses inflammatory responses through Nrf2 activation and NF-kappaB inactivation in lipopolysaccharide-stimulated BV-2 microglia. Mol Nutr Food Res 2015; 59: 1663-73.
    • (2015) Mol Nutr Food Res , vol.59 , pp. 1663-1673
    • Wu, W.1    Li, Y.2    Wu, Y.3    Zhang, Y.4    Wang, Z.5    Liu, X.6
  • 31
    • 84964757891 scopus 로고    scopus 로고
    • Lutein alleviates arsenic-induced reproductive toxicity in male mice via Nrf2 signaling
    • pii: 0960327115595682
    • Li SG, Xu SZ, Niu Q, et al. Lutein alleviates arsenic-induced reproductive toxicity in male mice via Nrf2 signaling. Hum Exp Toxicol 2015; pii: 0960327115595682.
    • (2015) Hum Exp Toxicol
    • Li, S.G.1    Xu, S.Z.2    Niu, Q.3
  • 32
    • 0030271387 scopus 로고    scopus 로고
    • NF-kappa B: Ten years after
    • Baeuerle PA, Baltimore D. NF-kappa B: Ten years after. Cell 1996; 87: 13-20.
    • (1996) Cell , vol.87 , pp. 13-20
    • Baeuerle, P.A.1    Baltimore, D.2
  • 34
    • 5444238022 scopus 로고    scopus 로고
    • The role of cytokines in cartilage matrix degeneration in osteoarthritis
    • Goldring SR, Goldring MB. The role of cytokines in cartilage matrix degeneration in osteoarthritis. Clin Orthop Relat Res 2004; 427 Suppl: S27-36.
    • (2004) Clin Orthop Relat Res , vol.427 , pp. S27-36
    • Goldring, S.R.1    Goldring, M.B.2
  • 35
    • 33745671359 scopus 로고    scopus 로고
    • Inhibitory effects of lutein on endotoxin-induced uveitis in Lewis rats
    • Jin XH, Ohgami K, Shiratori K, et al. Inhibitory effects of lutein on endotoxin-induced uveitis in Lewis rats. Invest Ophthalmol Vis Sci 2006; 47: 2562-8.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 2562-2568
    • Jin, X.H.1    Ohgami, K.2    Shiratori, K.3
  • 36
    • 80052726769 scopus 로고    scopus 로고
    • Beta-carotene and lutein inhibit hydrogen peroxide-induced activation of NF-kappaB and IL-8 expression in gastric epithelial AGS cells
    • Kim Y, Seo JH, Kim H. Beta-carotene and lutein inhibit hydrogen peroxide-induced activation of NF-kappaB and IL-8 expression in gastric epithelial AGS cells. J Nutr Sci Vitaminol (Tokyo) 2011; 57: 216-23.
    • (2011) J Nutr Sci Vitaminol (Tokyo) , vol.57 , pp. 216-223
    • Kim, Y.1    Seo, J.H.2    Kim, H.3
  • 37
    • 67651015980 scopus 로고    scopus 로고
    • Comparative effects of fatty acids on proinflammatory gene cyclooxygenase 2 and inducible nitric oxide synthase expression in retinal pigment epithelial cells
    • Fang IM, Yang CH, Yang CM, Chen MS. Comparative effects of fatty acids on proinflammatory gene cyclooxygenase 2 and inducible nitric oxide synthase expression in retinal pigment epithelial cells. Mol Nutr Food Res 2009; 53: 739-50.
    • (2009) Mol Nutr Food Res , vol.53 , pp. 739-750
    • Fang, I.M.1    Yang, C.H.2    Yang, C.M.3    Chen, M.S.4
  • 38
    • 0029787268 scopus 로고    scopus 로고
    • Molecular ordering of apoptotic mammalian CED-3/ICE-like proteases
    • Orth K, O'Rourke K, Salvesen GS, Dixit VM. Molecular ordering of apoptotic mammalian CED-3/ICE-like proteases. J Biol Chem 1996; 271: 20977-80.
    • (1996) J Biol Chem , vol.271 , pp. 20977-20980
    • Orth, K.1    O'Rourke, K.2    Salvesen, G.S.3    Dixit, V.M.4
  • 39
    • 0041528182 scopus 로고    scopus 로고
    • Dietary lutein inhibits mouse mammary tumor growth by regulating angiogenesis and apoptosis
    • Chew BP, Brown CM, Park JS, Mixter PF. Dietary lutein inhibits mouse mammary tumor growth by regulating angiogenesis and apoptosis. Anticancer Res 2003; 23: 3333-9.
    • (2003) Anticancer Res , vol.23 , pp. 3333-3339
    • Chew, B.P.1    Brown, C.M.2    Park, J.S.3    Mixter, P.F.4
  • 40
    • 38449115096 scopus 로고    scopus 로고
    • Lutein and zeaxanthin protect photoreceptors from apoptosis induced by oxidative stress: Relation with docosahexaenoic acid
    • Chucair AJ, Rotstein NP, Sangiovanni JP, During A, Chew EY, Politi LE. Lutein and zeaxanthin protect photoreceptors from apoptosis induced by oxidative stress: Relation with docosahexaenoic acid. Invest Ophthalmol Vis Sci 2007; 48: 5168-77.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 5168-5177
    • Chucair, A.J.1    Rotstein, N.P.2    Sangiovanni, J.P.3    During, A.4    Chew, E.Y.5    Politi, L.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.