Quercetin protects against lipopolysaccharide-induced acute lung injury in rats through suppression of inflammation and oxidative stress

Archives of Medical Science

Volumn 11, Issue 2, 2015, Pages 427-432

  Huang, Risheng ^a   Zhong, Tian ^b   Wu, Hao ^a  

^a WENZHOU CENTRAL HOSPITAL   (China)

^b SICHUAN PROVINCIAL PEOPLE'S HOSPITAL   (China)

Author keywords

Acute lung injury; Inflammation; Oxidative stress; Quercetin

Indexed keywords

CATALASE; GLUTATHIONE PEROXIDASE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MALONALDEHYDE; MYELOPEROXIDASE; QUERCETIN; SODIUM CHLORIDE; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA;

ACUTE LUNG INJURY; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMICAL ANALYSIS; CELL INFILTRATION; CONTROLLED STUDY; DRUG EFFECT; DRY WEIGHT; ENZYME ACTIVITY; ESCHERICHIA COLI; HISTOPATHOLOGY; LUNG ALVEOLUS WALL; LUNG EDEMA; LUNG LAVAGE; LUNG PARENCHYMA; MALE; NEUTROPHIL COUNT; NONHUMAN; OXIDATIVE STRESS; PNEUMONIA; RAT;

EID: 84928411648     PISSN: 17341922     EISSN: 18969151     Source Type: Journal    
DOI: 10.5114/aoms.2015.50975     Document Type: Article

References (30)

1. Martínez O, Nin N, Esteban A. Prone position for the treatment of acute respiratory distress syndrome: a review of current literature. Arch Bronconeumol 2009; 45: 291-6.
2. Wozniak K, Sleszycka J, Safianowska A, Wiechno W, Domagala-Kulawik J. Systemic inflammation in peripheral arterial disease with or without coexistent chronic obstructive pulmonary disease: analysis of selected markers. Arch Med Sci 2012; 8: 477-83.
3. Matute-Bello G, Frevert CW, Martin TR. Animal models of acute lung injury. Am J Physiol Lung Cell Mol Physiol 2008; 295: L379-99.
4. Ware LB, Matthay MA. The acute respiratory distress syndrome. N Engl J Med 2000; 342: 1334-49.
5. Beutler B, Rietschel ET. Innate immune sensing and its roots: the story of endotoxin. Nat Rev Immunol 2003; 3: 169-76.
6. Piotrowski WJ, Majewski S, Marczak J, Kurmanowska Z, Górski P, Antczak A. Exhaled breath 8-isoprostane as a marker of asthma severity. Arch Med Sci 2012; 8: 515-20.
7. Nijveldt RJ, van Nood E, van Hoorn DE, Boelens PG, van Norren K, van Leeuwen PA. Flavonoids: a review of probable mechanisms of action and potential applications. Am J Clin Nutr 2001; 74: 418-25.
8. Chu X, Ci X, Wei M, et al. Licochalcone a inhibits lipo-polysaccharide-induced inflammatory response in vitro and in vivo. J Agric Food Chem 2012; 60: 3947-54.
9. Boots AW, Haenen GR, Bast A. Health effects of quercetin: from antioxidant to nutraceutical. Eur J Pharmacol 2008; 585: 325-37.
10. Borska S, Gebarowska E, Wysocka T, Drag-Zalesińska M, Zabel M. The effects of quercetin vs cisplatin on proliferation and the apoptotic process in A549 and SW1271 cell lines in vitro conditions. Folia Morphol (Warsz) 2004; 63: 103-5.
11. Saito A, Sugisawa A, Umegaki K, Sunagawa H. Protective effects of quercetin and its metabolites on H2O2-induced chromosomal damage to WIL2-NS cells. Biosci Biotechnol Biochem 2004; 68: 271-6.
12. Park HK, Kim SJ, Kwon do Y, Park JH, Kim YC. Protective effect of quercetin against paraquat-induced lung injury in rats. Life Sci 2010; 87: 181-6.
13. Yang T, Luo F, Shen Y, et al. Quercetin attenuates airway inflammation and mucus production induced by cigarette smoke in rats. Int Immunopharmacol 2012; 13: 73-81.
14. Hayashi Y, Matsushima M, Nakamura T, et al. Quercetin protects against pulmonary oxidant stress via heme oxygenase-1 induction in lung epithelial cells. Biochem Biophys Res Commun 2012; 417: 169-74.
15. Zerin T, Kim YS, Hong SY, Song HY. Quercetin reduces oxidative damage induced by paraquat via modulating expression of antioxidant genes in A549 cells. J Appl Toxicol 2013; 33: 1460-7
16. McCarter SD, Mei SH, Lai PF, et al. Cell-based angiopoietin-1 gene therapy for acute lung injury. Am J Respir Crit Care Med 2007; 175: 1014-26.
17. Francescato HD, Coimbra TM, Costa RS, Bianchi Mde L. Protective effect of quercetin on the evolution of cisplatin-induced acute tubular necrosis. Kidney Blood Press Res 2004; 27: 148-58.
18. Ci X, Chu X, Wei M, Yang X, Cai Q, Deng X. Different effects of farrerol on an OVA-induced allergic asthma and LPS-induced acute lung injury. PLoS One 2012; 7: e34634.
19. Li X, Kovacs EJ, Schwacha MG, Chaudry IH, Choudhry MA. Acute alcohol intoxication increases interleukin-18-mediated neutrophil infiltration and lung inflammation following burn injury in rats. Am J Physiol Lung Cell Mol Physiol 2007; 292: L1193-201.
20. Trocha M, Merwid-Ląd A, Chlebda E, et al. Influence of ezetimibe on selected parameters of oxidative stress in rat liver subject to ischemia/reperfusion. Arch Med Sci 2014; 10: 817-24.
21. Goodman RB, Pugin J, Lee JS, Matthay MA. Cytokine-mediated inflammation in acute lung injury. Cytokine Growth Factor Rev 2003; 14: 523-35.
22. Tseng TL, Chen MF, Tsai MJ, Hsu YH, Chen CP, Lee TJ. Oroxylin-A rescues LPS-induced acute lung injury via regulation of NF-κB signaling pathway in rodents. PLoS One 2012; 7: e47403.
23. Soromou LW, Chen N, Jiang L, et al. Astragalin attenuates lipopolysaccharide-induced inflammatory responses by down-regulating NF-kappaB signaling pathway. Biochem Biophys Res Commun 2012; 419: 256-61.
24. Abraham E. Neutrophils and acute lung injury. Crit Care Med 2003; 31 (4 Suppl.): S195-9.
25. Sun L, Guo RF, Newstead MW, Standiford TJ, Macariola DR, Shanley TP. Effect of IL-10 on neutrophil recruitment and survival after Pseudomonas aeruginosa challenge. Am J Respir Cell Mol Biol 2009; 41: 76-84.
26. Huang CH, Yang ML, Tsai CH, Li YC, Lin YJ, Kuan YH. Ginkgo biloba leaves extract (EGb 761) attenuates lipopolysaccharide-induced acute lung injury via inhibition of oxidative stress and NF-kappaB-dependent matrix metalloproteinase-9 pathway. Phytomedicine 2013; 20: 303-9.
27. Kratzer E, Tian Y, Sarich N, et al. Oxidative stress contributes to lung injury and barrier dysfunction via microtubule destabilization. Am J Respir Cell Mol Biol 2012; 47: 688-97.
28. Czapski GA, Avram D, Sakharov DV, Wirtz KW, Strosznajder JB, Pap EH. Activated neutrophils oxidize extracellular proteins of endothelial cells in culture: effect of nitric oxide donors. Biochem J 2002; 365: 897-902.
29. Mariee AD, Abd-Allah GM, El-Beshbishy HA. Protective effect of dietary flavonoid quercetin against lipemic-oxidative hepatic injury in hypercholesterolemic rats. Pharm Biol 2012; 50: 1019-25.
30. Pandey AK, Patnaik R, Muresanu DF, Sharma A, Sharma HS. Quercetin in hypoxia-induced oxidative stress: novel target for neuroprotection. Int Rev Neurobiol 2012; 102: 107-46.