Therapeutic effect of the saponin fraction from Clematis chinensis osbeck roots on osteoarthritis induced by monosodium iodoacetate through protecting articular cartilage

Phytotherapy Research

Volumn 24, Issue 4, 2010, Pages 538-546

  Wu, Wenjun ^a   Xu, Xianxiang ^a   Dai, Yue ^a   Xia, Lunzhu ^b  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b ANHUI PROVINCIAL HOSPITAL   (China)

Author keywords

Chondrocytes; Clematis chinensis; Monosodium iodoacetate; Osteoarthritis

Indexed keywords

DICLOFENAC; IODOACETIC ACID; MONOSODIUM IODOACETATE; NITRIC OXIDE; NITROPRUSSIDE SODIUM; PROTEOGLYCAN; SAPONIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CARTILAGE INJURY; CELL DAMAGE; CELL PROTECTION; CLEMATIS; CLEMATIS CHINENSIS; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; HISTOPATHOLOGY; JOINT SWELLING; KNEE ARTHRITIS; MALE; NONHUMAN; OSTEOARTHRITIS; PLANT ROOT; PROTEIN DEGRADATION; RABBIT; RAT;

ALKYLATING AGENTS; ANIMALS; CARTILAGE, ARTICULAR; CELLS, CULTURED; CHONDROCYTES; CLEMATIS; DRUG EVALUATION, PRECLINICAL; INJECTIONS, INTRA-ARTICULAR; IODOACETATES; MALE; NITRIC OXIDE; NITRIC OXIDE DONORS; NITROPRUSSIDE; OSTEOARTHRITIS, KNEE; PHYTOTHERAPY; PLANT ROOTS; PROTEOGLYCANS; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; SAPONINS;

CLEMATIS CHINENSIS; ORYCTOLAGUS CUNICULUS; RATTUS;

EID: 77951587035     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.2977     Document Type: Article

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