Oxidative products from alcohol metabolism differentially modulate pro-inflammatory cytokine expression in Kupffer cells and hepatocytes

Cytokine

Volumn 85, Issue , 2016, Pages 109-119

  Dong, Daoyin ^a   Zhong, Wei ^a   Sun, Qian ^a   Zhang, Wenliang ^a   Sun, Xinguo ^a   Zhou, Zhanxiang ^a  

^a UNIVERSITY OF NORTH CAROLINA AT GREENSBORO   (United States)

Author keywords

4 HNE; Alcohol; Chemokines; Cytokines; Hepatocytes; Kupffer cells

Indexed keywords

4 HYDROXYNONENAL; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; GAMMA INTERFERON INDUCIBLE PROTEIN 10; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 1; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 2; TUMOR NECROSIS FACTOR ALPHA; ALCOHOL; CXCL1 CHEMOKINE; CYTOKINE; MESSENGER RNA; TUMOR NECROSIS FACTOR;

ALCOHOL INTOXICATION; ALCOHOL METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC STABILITY; HEPATITIS; HISTONE ACETYLATION; HISTOPATHOLOGY; IMMUNOPRECIPITATION; KUPFFER CELL; LIPID STORAGE; LIVER CELL; MALE; NONHUMAN; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; QUANTITATIVE ANALYSIS; RAT; REGULATORY MECHANISM; WESTERN BLOTTING; ANIMAL; DRUG EFFECTS; INFLAMMATION; LIVER; METABOLISM; PHYSIOLOGY; UPREGULATION; WISTAR RAT;

ANIMALS; CHEMOKINE CCL3; CHEMOKINE CXCL1; CHEMOKINE CXCL10; CYTOKINES; ETHANOL; HEPATOCYTES; INFLAMMATION; KUPFFER CELLS; LIPOPOLYSACCHARIDES; LIVER; MALE; NF-KAPPA B; OXIDATIVE STRESS; RATS; RATS, WISTAR; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 84977109251     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2016.06.014     Document Type: Article

References (45)

1. [1] McClain, C.J., Song, Z., Barve, S.S., Hill, D.B., Deaciuc, I., Recent advances in alcoholic liver disease. IV. Dysregulated cytokine metabolism in alcoholic liver disease. Am. J. Physiol. Gastrointest. Liver Physiol. 287 (2004), G497–502.
2. [2] Tilg, H., Diehl, A.M., Cytokines in alcoholic and nonalcoholic steatohepatitis. N. Engl. J. Med. 343 (2000), 1467–1476.
3. [3] An, L., Wang, X., Cederbaum, A.I., Cytokines in alcoholic liver disease. Arch. Toxicol. 86 (2012), 1337–1348.
4. [4] Iimuro, Y., Gallucci, R.M., Luster, M.I., Kono, H., Thurman, R.G., Antibodies to tumor necrosis factor alfa attenuate hepatic necrosis and inflammation caused by chronic exposure to ethanol in the rat. Hepatology 26 (1997), 1530–1537.
5. [5] Mandrekar, P., Ambade, A., Lim, A., Szabo, G., Catalano, D., An essential role for monocyte chemoattractant protein-1 in alcoholic liver injury: regulation of proinflammatory cytokines and hepatic steatosis in mice. Hepatology 54 (2011), 2185–2197.
6. [6] Zhao, Y., Zhong, W., Sun, X., Song, Z., Clemens, D.L., Kang, Y.J., et al. Zinc deprivation mediates alcohol-induced hepatocyte IL-8 analog expression in rodents via an epigenetic mechanism. Am. J. Pathol. 179 (2011), 693–702.
7. [7] Saiman, Y., Friedman, S.L., The role of chemokines in acute liver injury. Front. Physiol., 3, 2012, 213.
8. [8] Dominguez, M., Miquel, R., Colmenero, J., Moreno, M., Garcia-Pagan, J.C., Bosch, J., et al. Hepatic expression of CXC chemokines predicts portal hypertension and survival in patients with alcoholic hepatitis. Gastroenterology 136 (2009), 1639–1650.
9. [9] Hanck, C., Rossol, S., Bocker, U., Tokus, M., Singer, M.V., Presence of plasma endotoxin is correlated with tumour necrosis factor receptor levels and disease activity in alcoholic cirrhosis. Alcohol Alcohol. 33 (1998), 606–608.
10. [10] Roberts, R.A., Ganey, P.E., Ju, C., Kamendulis, L.M., Rusyn, I., Klaunig, J.E., Role of the Kupffer cell in mediating hepatic toxicity and carcinogenesis. Toxicol. Sci.: Off. J. Soc. Toxicol. 96 (2007), 2–15.
11. [11] Szabo, G., Dolganiuc, A., Dai, Q., Pruett, S.B., TLR4, ethanol, and lipid rafts: a new mechanism of ethanol action with implications for other receptor-mediated effects. J. Immunol. 178 (2007), 1243–1249.
12. [12] Zeldin, G., Yang, S.Q., Yin, M., Lin, H.Z., Rai, R., Diehl, A.M., Alcohol and cytokine-inducible transcription factors. Alcohol. Clin. Exp. Res. 20 (1996), 1639–1645.
13. [13] Mino, T., Takeuchi, O., Post-transcriptional regulation of cytokine mRNA controls the initiation and resolution of inflammation. Biotechnol. Genet. Eng. Rev. 29 (2013), 49–60.
14. [14] Holownia, A., Mroz, R.M., Wielgat, P., Jakubow, P., Jablonski, J., Sulek, J., et al. Histone acetylation and arachidonic acid cytotoxicity in HepG2 cells overexpressing CYP2E1. Naunyn-Schmiedeberg's Arch. Pharmacol. 387 (2014), 271–280.
15. [15] Kendrick, S.F., O'Boyle, G., Mann, J., Zeybel, M., Palmer, J., Jones, D.E., et al. Acetate, the key modulator of inflammatory responses in acute alcoholic hepatitis. Hepatology 51 (2010), 1988–1997.
16. [16] De Minicis, S., Bataller, R., Brenner, D.A., NADPH oxidase in the liver: defensive, offensive, or fibrogenic?. Gastroenterology 131 (2006), 272–275.
17. [17] De Minicis, S., Brenner, D.A., Oxidative stress in alcoholic liver disease: role of NADPH oxidase complex. J. Gastroenterol. Hepatol. 23:Suppl. 1 (2008), S98–S103.
18. [18] Hoek, J.B., Pastorino, J.G., Ethanol, oxidative stress, and cytokine-induced liver cell injury. Alcohol 27 (2002), 63–68.
19. [19] Brown, M.R., Miller, F.J. Jr., Li, W.G., Ellingson, A.N., Mozena, J.D., Chatterjee, P., et al. Overexpression of human catalase inhibits proliferation and promotes apoptosis in vascular smooth muscle cells. Circ. Res. 85 (1999), 524–533.
20. [20] Machino, T., Hashimoto, S., Maruoka, S., Gon, Y., Hayashi, S., Mizumura, K., et al. Apoptosis signal-regulating kinase 1-mediated signaling pathway regulates hydrogen peroxide-induced apoptosis in human pulmonary vascular endothelial cells. Crit. Care Med. 31 (2003), 2776–2781.
21. [21] Konishi, A., Aizawa, T., Mohan, A., Korshunov, V.A., Berk, B.C., Hydrogen peroxide activates the Gas6-Axl pathway in vascular smooth muscle cells. J. Biol. Chem. 279 (2004), 28766–28770.
22. 2-treated bovine endothelial cells. Free Radical Res. 36 (2002), 1147–1153.
23. [23] Sun, Q., Zhong, W., Zhang, W., Li, Q., Sun, X., Tan, X., et al. Zinc deficiency mediates alcohol-induced apoptotic cell death in the liver of rats through activating ER and mitochondrial cell death pathways. Am. J. Physiol. Gastrointest. Liver Physiol. 308 (2015), G757–G766.
24. [24] Coller, J., Methods to determine mRNA half-life in Saccharomyces cerevisiae. Methods Enzymol. 448 (2008), 267–284.
25. [25] Sharova, L.V., Sharov, A.A., Nedorezov, T., Piao, Y., Shaik, N., Ko, M.S., Database for mRNA half-life of 19 977 genes obtained by DNA microarray analysis of pluripotent and differentiating mouse embryonic stem cells. DNA Res.: Int. J. Rapid Publ. Rep. Genes Genomes 16 (2009), 45–58.
26. [26] Winzeler, E.A., Shoemaker, D.D., Astromoff, A., Liang, H., Anderson, K., Andre, B., et al. Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis. Science 285 (1999), 901–906.
27. [27] Kawaratani, H., Tsujimoto, T., Douhara, A., Takaya, H., Moriya, K., Namisaki, T., et al. The effect of inflammatory cytokines in alcoholic liver disease. Mediators Inflamm., 2013, 2013, 495156.
28. [28] Thurman, R.G. II., Alcoholic liver injury involves activation of Kupffer cells by endotoxin. Am. J. Physiol. 275 (1998), G605–G611.
29. [29] Adachi, Y., Bradford, B.U., Gao, W., Bojes, H.K., Thurman, R.G., Inactivation of Kupffer cells prevents early alcohol-induced liver injury. Hepatology 20 (1994), 453–460.
30. [30] Lawrence, T., The nuclear factor NF-kappaB pathway in inflammation. Cold Spring Harb. Perspect. Biol., 1, 2009, a001651.
31. [31] Ambade, A., Mandrekar, P., Oxidative stress and inflammation: essential partners in alcoholic liver disease. Int. J. Hepatol., 2012, 2012, 853175.
32. [32] Ito, K., Hanazawa, T., Tomita, K., Barnes, P.J., Adcock, I.M., Oxidative stress reduces histone deacetylase 2 activity and enhances IL-8 gene expression: role of tyrosine nitration. Biochem. Biophys. Res. Commun. 315 (2004), 240–245.
33. [33] Niu, Y., DesMarais, T.L., Tong, Z., Yao, Y., Costa, M., Oxidative stress alters global histone modification and DNA methylation. Free Radical Biol. Med. 82 (2015), 22–28.
34. [34] Esterbauer, H., Schaur, R.J., Zollner, H., Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radical Biol. Med. 11 (1991), 81–128.
35. [35] Go, Y.M., Halvey, P.J., Hansen, J.M., Reed, M., Pohl, J., Jones, D.P., Reactive aldehyde modification of thioredoxin-1 activates early steps of inflammation and cell adhesion. Am. J. Pathol. 171 (2007), 1670–1681.
36. [36] Rittner, H.L., Hafner, V., Klimiuk, P.A., Szweda, L.I., Goronzy, J.J., Weyand, C.M., Aldose reductase functions as a detoxification system for lipid peroxidation products in vasculitis. J. Clin. Investig. 103 (1999), 1007–1013.
37. [37] Henriksen, P.A., Hitt, M., Xing, Z., Wang, J., Haslett, C., Riemersma, R.A., et al. Adenoviral gene delivery of elafin and secretory leukocyte protease inhibitor attenuates NF-kappa B-dependent inflammatory responses of human endothelial cells and macrophages to atherogenic stimuli. J. Immunol. 172 (2004), 4535–4544.
38. [38] Kamimura, S., Gaal, K., Britton, R.S., Bacon, B.R., Triadafilopoulos, G., Tsukamoto, H., Increased 4-hydroxynonenal levels in experimental alcoholic liver disease: association of lipid peroxidation with liver fibrogenesis. Hepatology 16 (1992), 448–453.
39. [39] Luckey, S.W., Taylor, M., Sampey, B.P., Scheinman, R.I., Petersen, D.R., 4-hydroxynonenal decreases interleukin-6 expression and protein production in primary rat Kupffer cells by inhibiting nuclear factor-kappaB activation. J. Pharmacol. Exp. Ther. 302 (2002), 296–303.
40. [40] Kim, Y.S., Park, Z.Y., Kim, S.Y., Jeong, E., Lee, J.Y., Alteration of Toll-like receptor 4 activation by 4-hydroxy-2-nonenal mediated by the suppression of receptor homodimerization. Chem. Biol. Interact. 182 (2009), 59–66.
41. [41] Hartley, D.P., Ruth, J.A., Petersen, D.R., The hepatocellular metabolism of 4-hydroxynonenal by alcohol dehydrogenase, aldehyde dehydrogenase, and glutathione S-transferase. Arch. Biochem. Biophys. 316 (1995), 197–205.
42. [42] Esterbauer, H., Zollner, H., Lang, J., Metabolism of the lipid peroxidation product 4-hydroxynonenal by isolated hepatocytes and by liver cytosolic fractions. Biochem. J. 228 (1985), 363–373.
43. [43] Siems, W.G., Zollner, H., Grune, T., Esterbauer, H., Metabolic fate of 4-hydroxynonenal in hepatocytes: 1,4-dihydroxynonene is not the main product. J. Lipid Res. 38 (1997), 612–622.
44. [44] Tiedje, C., Holtmann, H., Gaestel, M., The role of mammalian MAPK signaling in regulation of cytokine mRNA stability and translation. J. Interferon Cytokine Res.: Off. J. Int. Soc. Interferon Cytokine Res. 34 (2014), 220–232.
45. [45] Hollams, E.M., Giles, K.M., Thomson, A.M., Leedman, P.J., MRNA stability and the control of gene expression: implications for human disease. Neurochem. Res. 27 (2002), 957–980.