Platelet-derived growth factor (PDGF)-induced activation of Erk5 MAP-kinase is dependent on Mekk2, Mek1/2, PKC and PI3-kinase, and affects BMP signaling

Cellular Signalling

Volumn 28, Issue 9, 2016, Pages 1422-1431

  Tsioumpekou, Maria ^a   Papadopoulos, Natalia ^a   Burovic, Fatima ^a   Heldin, Carl Henrik ^a   Lennartsson, Johan ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Erk5; MAP kinase; Mekk2; PDGFR ; PKC; Smad

Indexed keywords

BONE MORPHOGENETIC PROTEIN; INHIBITOR OF DIFFERENTIATION 3; MITOGEN ACTIVATED PROTEIN KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 2; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR BB; PROTEIN KINASE C; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD7 PROTEIN; SMAD8 PROTEIN; IDB3 PROTEIN, MOUSE; INHIBITOR OF DIFFERENTIATION PROTEIN; MAP2K1 PROTEIN, MOUSE; MAP2K2 PROTEIN, MOUSE; PLATELET DERIVED GROWTH FACTOR; SMAD PROTEIN;

ANIMAL CELL; ARTICLE; CELL LINE; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; ENZYME REGULATION; GENE EXPRESSION; MOVAS CELL LINE; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ANIMAL; DRUG EFFECTS; HEK293 CELL LINE; HUMAN; METABOLISM; MOUSE; NIH 3T3 CELL LINE; PHOSPHORYLATION;

ANIMALS; BONE MORPHOGENETIC PROTEINS; ENZYME ACTIVATION; HEK293 CELLS; HUMANS; INHIBITOR OF DIFFERENTIATION PROTEINS; MAP KINASE KINASE 1; MAP KINASE KINASE 2; MAP KINASE KINASE KINASE 2; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 7; NIH 3T3 CELLS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; PROTEIN KINASE C; SIGNAL TRANSDUCTION; SMAD PROTEINS;

EID: 84977070915     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2016.06.013     Document Type: Article

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