메뉴 건너뛰기




Volumn 48, Issue 1, 2008, Pages 107-115

ERK5 differentially regulates PDGF-induced proliferation and migration of hepatic stellate cells

Author keywords

BMK1; Cell migration; Cell proliferation; ERK5; Hepatic fibrosis; Hepatic stellate cells; MAPK7; Mitogen activated protein kinase; Platelet derived growth factor; Signal transduction

Indexed keywords

EPIDERMAL GROWTH FACTOR; FOCAL ADHESION KINASE; MITOGEN ACTIVATED PROTEIN KINASE 7; P21 ACTIVATED KINASE; PAXILLIN; PLATELET DERIVED GROWTH FACTOR; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE;

EID: 36549082913     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2007.08.010     Document Type: Article
Times cited : (57)

References (41)
  • 1
    • 0029162078 scopus 로고
    • Primary structure of BMK1: a new mammalian map kinase
    • Lee J.D., Ulevitch R.J., and Han J. Primary structure of BMK1: a new mammalian map kinase. Biochem Biophys Res Commun 213 (1995) 715-724
    • (1995) Biochem Biophys Res Commun , vol.213 , pp. 715-724
    • Lee, J.D.1    Ulevitch, R.J.2    Han, J.3
  • 2
    • 0029055761 scopus 로고
    • Components of a new human protein kinase signal transduction pathway
    • Zhou G., Bao Z.Q., and Dixon J.E. Components of a new human protein kinase signal transduction pathway. J Biol Chem 270 (1995) 12665-12669
    • (1995) J Biol Chem , vol.270 , pp. 12665-12669
    • Zhou, G.1    Bao, Z.Q.2    Dixon, J.E.3
  • 3
    • 0035815665 scopus 로고    scopus 로고
    • Molecular cloning of mouse ERK5/BMK1 splice variants and characterization of ERK5 functional domains
    • Yan C., Luo H., Lee J.D., Abe J., and Berk B.C. Molecular cloning of mouse ERK5/BMK1 splice variants and characterization of ERK5 functional domains. J Biol Chem 276 (2001) 10870-10878
    • (2001) J Biol Chem , vol.276 , pp. 10870-10878
    • Yan, C.1    Luo, H.2    Lee, J.D.3    Abe, J.4    Berk, B.C.5
  • 4
    • 0029896250 scopus 로고    scopus 로고
    • Big mitogen-activated protein kinase 1 (BMK1) is a redox-sensitive kinase
    • Abe J., Kusuhara M., Ulevitch R.J., Berk B.C., and Lee J.D. Big mitogen-activated protein kinase 1 (BMK1) is a redox-sensitive kinase. J Biol Chem 271 (1996) 16586-16590
    • (1996) J Biol Chem , vol.271 , pp. 16586-16590
    • Abe, J.1    Kusuhara, M.2    Ulevitch, R.J.3    Berk, B.C.4    Lee, J.D.5
  • 5
    • 0033543549 scopus 로고    scopus 로고
    • Activation of the protein kinase ERK5/BMK1 by receptor tyrosine kinases. Identification and characterization of a signaling pathway to the nucleus
    • Kamakura S., Moriguchi T., and Nishida E. Activation of the protein kinase ERK5/BMK1 by receptor tyrosine kinases. Identification and characterization of a signaling pathway to the nucleus. J Biol Chem 274 (1999) 26563-26571
    • (1999) J Biol Chem , vol.274 , pp. 26563-26571
    • Kamakura, S.1    Moriguchi, T.2    Nishida, E.3
  • 6
    • 32144436881 scopus 로고    scopus 로고
    • Regulation of cellular functions by the ERK5 signalling pathway
    • Wang X., and Tournier C. Regulation of cellular functions by the ERK5 signalling pathway. Cell Signal 18 (2006) 753-760
    • (2006) Cell Signal , vol.18 , pp. 753-760
    • Wang, X.1    Tournier, C.2
  • 7
    • 0041834594 scopus 로고    scopus 로고
    • Activation of cyclin D1 expression by the ERK5 cascade
    • Mulloy R., Salinas S., Philips A., and Hipskind R.A. Activation of cyclin D1 expression by the ERK5 cascade. Oncogene 22 (2003) 5387-5398
    • (2003) Oncogene , vol.22 , pp. 5387-5398
    • Mulloy, R.1    Salinas, S.2    Philips, A.3    Hipskind, R.A.4
  • 8
    • 0035815691 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor induces ERK5 activation, which is differentially regulated by protein-tyrosine kinases and protein kinase C. Regulation of cell proliferation and survival
    • Dong F., Gutkind J.S., and Larner A.C. Granulocyte colony-stimulating factor induces ERK5 activation, which is differentially regulated by protein-tyrosine kinases and protein kinase C. Regulation of cell proliferation and survival. J Biol Chem 276 (2001) 10811-10816
    • (2001) J Biol Chem , vol.276 , pp. 10811-10816
    • Dong, F.1    Gutkind, J.S.2    Larner, A.C.3
  • 9
    • 0032531881 scopus 로고    scopus 로고
    • Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor
    • Kato Y., Tapping R.I., Huang S., Watson M.H., Ulevitch R.J., and Lee J.D. Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor. Nature 395 (1998) 713-716
    • (1998) Nature , vol.395 , pp. 713-716
    • Kato, Y.1    Tapping, R.I.2    Huang, S.3    Watson, M.H.4    Ulevitch, R.J.5    Lee, J.D.6
  • 10
    • 0034769309 scopus 로고    scopus 로고
    • Extracellular signal regulated kinase 5 (ERK5) is required for the differentiation of muscle cells
    • Dinev D., Jordan B.W., Neufeld B., Lee J.D., Lindemann D., Rapp U.R., et al. Extracellular signal regulated kinase 5 (ERK5) is required for the differentiation of muscle cells. EMBO Rep 2 (2001) 829-834
    • (2001) EMBO Rep , vol.2 , pp. 829-834
    • Dinev, D.1    Jordan, B.W.2    Neufeld, B.3    Lee, J.D.4    Lindemann, D.5    Rapp, U.R.6
  • 11
    • 0034723290 scopus 로고    scopus 로고
    • Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury
    • Friedman S.L. Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. J Biol Chem 275 (2000) 2247-2250
    • (2000) J Biol Chem , vol.275 , pp. 2247-2250
    • Friedman, S.L.1
  • 13
    • 0034810089 scopus 로고    scopus 로고
    • Cytokine receptors and signaling in hepatic stellate cells
    • Pinzani M., and Marra F. Cytokine receptors and signaling in hepatic stellate cells. Semin Liver Dis 21 (2001) 397-416
    • (2001) Semin Liver Dis , vol.21 , pp. 397-416
    • Pinzani, M.1    Marra, F.2
  • 14
    • 0027234054 scopus 로고
    • Regulation of extracellular matrix synthesis by transforming growth factor beta1 in human fat-storing cells
    • Casini A., Pinzani M., Milani S., Grappone C., Galli G., Jezequel A.M., et al. Regulation of extracellular matrix synthesis by transforming growth factor beta1 in human fat-storing cells. Gastroenterology 105 (1993) 245-253
    • (1993) Gastroenterology , vol.105 , pp. 245-253
    • Casini, A.1    Pinzani, M.2    Milani, S.3    Grappone, C.4    Galli, G.5    Jezequel, A.M.6
  • 15
    • 0035971215 scopus 로고    scopus 로고
    • Signal transduction by the chemokine receptor CXCR3. Activation of Ras/ERK, Src and PI 3-K/Akt controls cell migration and proliferation in human vascular pericytes
    • Bonacchi A., Romagnani P., Romanelli R.G., Efsen E., Annunziato F., Lasagni L., et al. Signal transduction by the chemokine receptor CXCR3. Activation of Ras/ERK, Src and PI 3-K/Akt controls cell migration and proliferation in human vascular pericytes. J Biol Chem 276 (2001) 9945-9954
    • (2001) J Biol Chem , vol.276 , pp. 9945-9954
    • Bonacchi, A.1    Romagnani, P.2    Romanelli, R.G.3    Efsen, E.4    Annunziato, F.5    Lasagni, L.6
  • 16
    • 29244466499 scopus 로고    scopus 로고
    • Dose-dependent and divergent effects of superoxide anion on cell death, proliferation and migration of activated human hepatic stellate cells
    • Novo E., Marra F., Zamara E., Valfrè di Bonzo L., Caligiuri A., Cannito S., et al. Dose-dependent and divergent effects of superoxide anion on cell death, proliferation and migration of activated human hepatic stellate cells. Gut 55 (2006) 90-97
    • (2006) Gut , vol.55 , pp. 90-97
    • Novo, E.1    Marra, F.2    Zamara, E.3    Valfrè di Bonzo, L.4    Caligiuri, A.5    Cannito, S.6
  • 17
    • 15744403731 scopus 로고    scopus 로고
    • Binding of hepatitis C virus envelope protein E2 to CD81 up-regulates matrix metalloproteinase-2 in human hepatic stellate cells
    • Mazzocca A., Sciammetta S.C., Carloni V., Cosmi L., Annunziato F., Harada T., et al. Binding of hepatitis C virus envelope protein E2 to CD81 up-regulates matrix metalloproteinase-2 in human hepatic stellate cells. J Biol Chem 280 (2005) 11329-11339
    • (2005) J Biol Chem , vol.280 , pp. 11329-11339
    • Mazzocca, A.1    Sciammetta, S.C.2    Carloni, V.3    Cosmi, L.4    Annunziato, F.5    Harada, T.6
  • 19
    • 0030761765 scopus 로고    scopus 로고
    • c-Src is required for oxidative stress-mediated activation of big mitogen-activated protein kinase 1
    • Abe J., Takahashi M., Ishida M., Lee J.D., and Berk B.C. c-Src is required for oxidative stress-mediated activation of big mitogen-activated protein kinase 1. J Biol Chem 272 (1997) 20389-20394
    • (1997) J Biol Chem , vol.272 , pp. 20389-20394
    • Abe, J.1    Takahashi, M.2    Ishida, M.3    Lee, J.D.4    Berk, B.C.5
  • 20
    • 1242272926 scopus 로고    scopus 로고
    • Src-dependent ERK5 and Src/EGFR-dependent ERK1/2 activation is required for cell proliferation by asbestos
    • Scapoli L., Ramos-Nino M.E., Martinelli M., and Mossman B.T. Src-dependent ERK5 and Src/EGFR-dependent ERK1/2 activation is required for cell proliferation by asbestos. Oncogene 23 (2004) 805-813
    • (2004) Oncogene , vol.23 , pp. 805-813
    • Scapoli, L.1    Ramos-Nino, M.E.2    Martinelli, M.3    Mossman, B.T.4
  • 21
    • 0030694387 scopus 로고    scopus 로고
    • BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C
    • Kato Y., Kravchenko V.V., Tapping R.I., Han J., Ulevitch R.J., and Lee J.D. BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C. EMBO J 16 (1997) 7054-7066
    • (1997) EMBO J , vol.16 , pp. 7054-7066
    • Kato, Y.1    Kravchenko, V.V.2    Tapping, R.I.3    Han, J.4    Ulevitch, R.J.5    Lee, J.D.6
  • 22
    • 0031004620 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase is required for platelet-derived growth factor's actions on hepatic stellate cells
    • Marra F., Gentilini A., Pinzani M., Ghosh Choudhury G., Parola M., Herbst H., et al. Phosphatidylinositol 3-kinase is required for platelet-derived growth factor's actions on hepatic stellate cells. Gastroenterology 112 (1997) 1297-1306
    • (1997) Gastroenterology , vol.112 , pp. 1297-1306
    • Marra, F.1    Gentilini, A.2    Pinzani, M.3    Ghosh Choudhury, G.4    Parola, M.5    Herbst, H.6
  • 23
    • 11244258882 scopus 로고    scopus 로고
    • Focal adhesion kinase: in command and control of cell motility
    • Mitra S.K., Hanson D.A., and Schlaepfer D.D. Focal adhesion kinase: in command and control of cell motility. Nat Rev Mol Cell Biol 6 (2005) 56-68
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 56-68
    • Mitra, S.K.1    Hanson, D.A.2    Schlaepfer, D.D.3
  • 24
    • 0035920139 scopus 로고    scopus 로고
    • Platelet-derived growth factor requires epidermal growth factor receptor to activate p21-activated kinase family kinases
    • He H., Levitzki A., Zhu H.J., Walker F., Burgess A., and Maruta H. Platelet-derived growth factor requires epidermal growth factor receptor to activate p21-activated kinase family kinases. J Biol Chem 276 (2001) 26741-26744
    • (2001) J Biol Chem , vol.276 , pp. 26741-26744
    • He, H.1    Levitzki, A.2    Zhu, H.J.3    Walker, F.4    Burgess, A.5    Maruta, H.6
  • 25
    • 0028085979 scopus 로고
    • Regulation of platelet-derived growth factor secretion and gene expression in human liver fat-storing cells
    • Marra F., Ghosh Choudhury G., Pinzani M., and Abboud H.E. Regulation of platelet-derived growth factor secretion and gene expression in human liver fat-storing cells. Gastroenterology 107 (1994) 1110-1117
    • (1994) Gastroenterology , vol.107 , pp. 1110-1117
    • Marra, F.1    Ghosh Choudhury, G.2    Pinzani, M.3    Abboud, H.E.4
  • 26
    • 0030091214 scopus 로고    scopus 로고
    • Expression of platelet-derived growth factor and its receptors in normal human liver and during active hepatic fibrogenesis
    • Pinzani M., Milani S., Herbst H., DeFranco R., Grappone C., Gentilini A., et al. Expression of platelet-derived growth factor and its receptors in normal human liver and during active hepatic fibrogenesis. Am J Pathol 148 (1996) 785-800
    • (1996) Am J Pathol , vol.148 , pp. 785-800
    • Pinzani, M.1    Milani, S.2    Herbst, H.3    DeFranco, R.4    Grappone, C.5    Gentilini, A.6
  • 27
    • 0033066133 scopus 로고    scopus 로고
    • Expression of platelet-derived growth factor in newly formed cholangiocytes during experimental biliary fibrosis in rats
    • Grappone C., Pinzani M., Parola M., Pellegrini G., Caligiuri A., DeFranco R., et al. Expression of platelet-derived growth factor in newly formed cholangiocytes during experimental biliary fibrosis in rats. J Hepatol 31 (1999) 100-109
    • (1999) J Hepatol , vol.31 , pp. 100-109
    • Grappone, C.1    Pinzani, M.2    Parola, M.3    Pellegrini, G.4    Caligiuri, A.5    DeFranco, R.6
  • 31
    • 20444389754 scopus 로고    scopus 로고
    • Identification of WNK1 as a substrate of Akt/protein kinase B and a negative regulator of insulin-stimulated mitogenesis in 3T3-L1 cells
    • Jiang Z.Y., Zhou Q.L., Holik J., Patel S., Leszyk J., Coleman K., et al. Identification of WNK1 as a substrate of Akt/protein kinase B and a negative regulator of insulin-stimulated mitogenesis in 3T3-L1 cells. J Biol Chem 280 (2005) 21622-21628
    • (2005) J Biol Chem , vol.280 , pp. 21622-21628
    • Jiang, Z.Y.1    Zhou, Q.L.2    Holik, J.3    Patel, S.4    Leszyk, J.5    Coleman, K.6
  • 32
    • 0033761543 scopus 로고    scopus 로고
    • ERK5 is a novel type of mitogen-activated protein kinase containing a transcriptional activation domain
    • Kasler H.G., Victoria J., Duramad O., and Winoto A. ERK5 is a novel type of mitogen-activated protein kinase containing a transcriptional activation domain. Mol Cell Biol 20 (2000) 8382-8389
    • (2000) Mol Cell Biol , vol.20 , pp. 8382-8389
    • Kasler, H.G.1    Victoria, J.2    Duramad, O.3    Winoto, A.4
  • 34
    • 0036826888 scopus 로고    scopus 로고
    • Low Mr phosphotyrosine protein phosphatase associates and dephosphorylates p125 focal adhesion kinase, interfering with cell motility and spreading
    • Rigacci S., Rovida E., Sbarba P.D., and Berti A. Low Mr phosphotyrosine protein phosphatase associates and dephosphorylates p125 focal adhesion kinase, interfering with cell motility and spreading. J Biol Chem 277 (2002) 41631-41636
    • (2002) J Biol Chem , vol.277 , pp. 41631-41636
    • Rigacci, S.1    Rovida, E.2    Sbarba, P.D.3    Berti, A.4
  • 35
    • 0030772657 scopus 로고    scopus 로고
    • Localization of p21-activated kinase 1 (PAK1) to pinocytic vesicles and cortical actin structures in stimulated cells
    • Dharmawardhane S., Sanders L.C., Martin S.S., Daniels R.H., and Bokoch G.M. Localization of p21-activated kinase 1 (PAK1) to pinocytic vesicles and cortical actin structures in stimulated cells. J Cell Biol 138 (1997) 1265-1278
    • (1997) J Cell Biol , vol.138 , pp. 1265-1278
    • Dharmawardhane, S.1    Sanders, L.C.2    Martin, S.S.3    Daniels, R.H.4    Bokoch, G.M.5
  • 36
    • 0032871296 scopus 로고    scopus 로고
    • Localization of p21-activated kinase 1 (PAK1) to pseudopodia, membrane ruffles, and phagocytic cups in activated human neutrophils
    • Dharmawardhane S., Brownson D., Lennartz M., and Bokoch G.M. Localization of p21-activated kinase 1 (PAK1) to pseudopodia, membrane ruffles, and phagocytic cups in activated human neutrophils. J Leukoc Biol 66 (1999) 521-527
    • (1999) J Leukoc Biol , vol.66 , pp. 521-527
    • Dharmawardhane, S.1    Brownson, D.2    Lennartz, M.3    Bokoch, G.M.4
  • 37
    • 0034739851 scopus 로고    scopus 로고
    • Temporal and spatial distribution of activated Pak1 in fibroblasts
    • Sells M.A., Pfaff A., and Chernoff J. Temporal and spatial distribution of activated Pak1 in fibroblasts. J Cell Biol 151 (2000) 1449-1458
    • (2000) J Cell Biol , vol.151 , pp. 1449-1458
    • Sells, M.A.1    Pfaff, A.2    Chernoff, J.3
  • 38
    • 0033577902 scopus 로고    scopus 로고
    • p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts
    • Sells M.A., Boyd J.T., and Chernoff J. p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts. J Cell Biol 145 (1999) 837-849
    • (1999) J Cell Biol , vol.145 , pp. 837-849
    • Sells, M.A.1    Boyd, J.T.2    Chernoff, J.3
  • 40
    • 0038554077 scopus 로고    scopus 로고
    • Biology of the p21-activated kinases
    • Bokoch G.M. Biology of the p21-activated kinases. Annu Rev Biochem 72 (2003) 743-781
    • (2003) Annu Rev Biochem , vol.72 , pp. 743-781
    • Bokoch, G.M.1
  • 41
    • 0742295936 scopus 로고    scopus 로고
    • Chemokines in liver inflammation and fibrosis
    • Marra F. Chemokines in liver inflammation and fibrosis. Front Biosci 7 (2002) D1899-D1914
    • (2002) Front Biosci , vol.7
    • Marra, F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.