A positive feedback loop involving Erk5 and Akt turns on mesangial cell proliferation in response to PDGF

American Journal of Physiology - Cell Physiology

Volumn 306, Issue 11, 2014, Pages

  Bera, Amit ^c   Das, Falguni ^c   Ghosh Choudhury, Nandini ^a,b   Li, Xiaonan ^c   Pal, Sanjay ^c   Gorin, Yves ^c   Kasinath, Balakuntalam S ^a,c   Abboud, Hanna E ^a,c   Ghosh Choudhury, Goutam ^a,c  

^a SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

^b Mays Cancer Center at UT Health San Antonio   (United States)

^c UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

Akt kinase; Cell proliferation; MAP kinase; Receptor tyrosine kinase; Renal physiology

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE 4; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 7; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE B; RETINOBLASTOMA PROTEIN; TYROSINE;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; DNA SYNTHESIS; ENZYME ACTIVITY; MESANGIUM CELL; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

AKT KINASE; CELL PROLIFERATION; MAP KINASE; RECEPTOR TYROSINE KINASE; RENAL PHYSIOLOGY;

ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; FEEDBACK, PHYSIOLOGICAL; MESANGIAL CELLS; MITOGEN-ACTIVATED PROTEIN KINASE 7; ONCOGENE PROTEIN V-AKT; PLATELET-DERIVED GROWTH FACTOR; RATS;

EID: 84901781034     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00387.2013     Document Type: Article

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