SCOPUS 정보 검색 플랫폼

Volumn , Issue , 2016, Pages 1264-1269

Design, Synthesis and in vitro Evaluation of Indolotacrine Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease

(13) Benek, Ondrej a,b,c Soukup, Ondrej b,c Pasdiorova, Marketa a,c Hroch, Lukas c,d Sepsova, Vendula a,c Jost, Petr a,c Hrabinova, Martina a,c Jun, Daniel a Kuca, Kamil c,g Zala, Dominykas e Ramsay, Rona R e Marco Contelles, José f Musilek, Kamil c,g

a UNIVERSITY OF DEFENCE (Czech Republic)

b NATIONAL INSTITUTE OF MENTAL HEALTH (Czech Republic)

c UNIVERSITY HOSPITAL HRADEC KRALOVE (Czech Republic)

d Charles University in Prague Faculty of Pharmacy (Czech Republic)

e UNIVERSITY OF ST ANDREWS (United Kingdom)

f INSTITUTO DE QUÍMICA ORGÁNICA GENERAL (Spain)

g UNIVERSITY OF HRADEC KRALOVE (Czech Republic)

Author keywords

Alzheimer's disease; cholinesterases; cytotoxicity; inhibitors; monoamine oxidase; multitarget directed ligands

Indexed keywords

CHOLINESTERASE INHIBITOR; INDOLOTACRINE DERIVATIVE; MONOAMINE OXIDASE INHIBITOR; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD BRAIN BARRIER; CYTOTOXICITY; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; IC50; IN VITRO STUDY; LIVER TOXICITY; NEUROTRANSMISSION; PRIORITY JOURNAL; STEREOSPECIFICITY;

EID: 84976521292 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.201500383 Document Type: Article

Times cited : (34)

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