Toll-Like receptor 2 stimulation of osteoblasts mediates staphylococcus aureus induced bone resorption and osteoclastogenesis through enhanced RANKL

PLoS ONE

Volumn 11, Issue 6, 2016, Pages

  Kassem, Ali ^a   Lindholm, Catharina ^b   Lerner, Ulf H ^a,b  

^a UMEÅ UNIVERSITY   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PROSTAGLANDIN; TOLL LIKE RECEPTOR 2; TLR2 PROTEIN, MOUSE; TNFRSF11B PROTEIN, MOUSE; TNFSF11 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CELL ISOLATION; CYTOKINE PRODUCTION; GENE EXPRESSION REGULATION; GENE INACTIVATION; MACROPHAGE; MOUSE; NONHUMAN; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; OSTEOPROGENITOR CELL; PARIETAL BONE; PERIOSTEUM; PROTEIN EXPRESSION; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; TNFSF11 GENE; ANIMAL; BIOSYNTHESIS; BONE DEVELOPMENT; C57BL MOUSE; DEFICIENCY; GENETICS; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MICROBIOLOGY; NEWBORN; OSTEOBLAST; PATHOGENICITY; PATHOLOGY; PRIMARY CELL CULTURE; SIGNAL TRANSDUCTION;

ANIMALS; ANIMALS, NEWBORN; BONE MARROW CELLS; BONE RESORPTION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OSTEOBLASTS; OSTEOCLASTS; OSTEOGENESIS; OSTEOPROTEGERIN; PARIETAL BONE; PRIMARY CELL CULTURE; PROSTAGLANDINS; RANK LIGAND; RNA, MESSENGER; SIGNAL TRANSDUCTION; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; TOLL-LIKE RECEPTOR 2;

EID: 84976418056     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0156708     Document Type: Article

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