Urinary Tissue Inhibitor of Metalloproteinase-2 and Insulin-Like Growth Factor-Binding Protein 7 for Risk Stratification of Acute Kidney Injury in Patients with Sepsis

Critical Care Medicine

Volumn 44, Issue 10, 2016, Pages 1851-1860

  Honore, Patrick M ^a   Nguyen, H Bryant ^b   Gong, Michelle ^c   Chawla, Lakhmir S ^d   Bagshaw, Sean M ^e   Artigas, Antonio ^f   Shi, Jing ^g   Joannes Boyau, Olivier ^h   Vincent, Jean Louis ⁱ   Kellum, John A ^j  

^a UNIVERSITY HOSPITAL BRUSSELS   (Belgium)

^b LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^d GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

^e UNIVERSITY OF ALBERTA   (Canada)

^f UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^g Walker Bioscience   (United States)

^h HAUT LÉVÊQUE HOSPITAL   (France)

ⁱ ERASME HOSPITAL   (Belgium)

^j UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

more..

Author keywords

acute kidney injury; insulin like growth factor binding protein 7; organ dysfunction; risk prediction; sepsis; tissue inhibitor of metalloproteinase 2

Indexed keywords

BIOLOGICAL MARKER; CREATININE; INSULIN LIKE GROWTH FACTOR BINDING PROTEIN 7; SOMATOMEDIN BINDING PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE 2; UNCLASSIFIED DRUG; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED PROTEIN 1;

ACUTE KIDNEY FAILURE; ADULT; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CRITICALLY ILL PATIENT; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE SEVERITY; EUROPE; FEMALE; HOSPITAL ADMISSION; HUMAN; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MULTIPLE ORGAN FAILURE; NORMAL VALUE; NORTH AMERICA; PREDICTIVE VALUE; PRIORITY JOURNAL; PROTEIN URINE LEVEL; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SEPSIS; SEQUENTIAL ORGAN FAILURE ASSESSMENT SCORE; AGED; BLOOD; BODY MASS; CLINICAL TRIAL; COMPLICATION; MULTICENTER STUDY; ORGAN DYSFUNCTION SCORE; PROSPECTIVE STUDY; RECEIVER OPERATING CHARACTERISTIC; SEVERITY OF ILLNESS INDEX; URINE; VERY ELDERLY;

ACUTE KIDNEY INJURY; AGED; AGED, 80 AND OVER; BIOMARKERS; BODY MASS INDEX; CREATININE; FEMALE; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS; MALE; MIDDLE AGED; ORGAN DYSFUNCTION SCORES; PROSPECTIVE STUDIES; ROC CURVE; SEPSIS; SEVERITY OF ILLNESS INDEX; TISSUE INHIBITOR OF METALLOPROTEINASE-2;

EID: 84976416918     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0000000000001827     Document Type: Article

References (49)

1. Murugan R, Karajala-Subramanyam V, Lee M, et al: Genetic and Inflammatory Markers of Sepsis (GenIMS) Investigators: Acute kidney injury in non-severe pneumonia is associated with an increased immune response and lower survival. Kidney Int 2010; 77: 527-535
2. Bagshaw SM, Uchino S, Bellomo R, et al: Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators: Septic acute kidney injury in critically ill patients: Clinical characteristics and outcomes. Clin J Am Soc Nephrol 2007; 2: 431-439
3. Mehta RL, Bouchard J, Soroko SB, et al: Program to Improve Care in Acute Renal Disease (PICARD) Study Group: Sepsis as a cause and consequence of acute kidney injury: Program to Improve Care in Acute Renal Disease. Intensive Care Med 2011; 37: 241-248
4. Godin M, Murray P, Mehta RL: Clinical approach to the patient with AKI and sepsis. Semin Nephrol 2015; 35: 12-22
5. Schortgen F, Asfar P: Update in sepsis and acute kidney injury in 2014. Am J Respir Crit Care Med 2015; 191: 1236-1231
6. Alobaidi R, Basu RK, Goldstein SL, et al: Sepsis-associated acute kidney injury. Semin Nephrol 2015; 35: 2-11
7. Honore PM, Jacobs R, Joannes-Boyau O, et al: Septic AKI in ICU patients. diagnosis, pathophysiology, and treatment type, dosing, and timing: A comprehensive review of recent and future developments. Ann Intensive Care 2011; 1: 32
8. Medeiros P, Nga HS, Menezes P, et al: Acute kidney injury in septic patients admitted to emergency clinical room: Risk factors and outcome. Clin Exp Nephrol 2015; 19: 859-866
9. Ahmed W, Memon JI, Rehmani R, et al: Outcome of patients with acute kidney injury in severe sepsis and septic shock treated with early goal-directed therapy in an intensive care unit. Saudi J Kidney Dis Transpl 2014; 25: 544-551
10. Murray PT, Mehta RL, Shaw A, et al: ADQI 10 Workgroup: Potential use of biomarkers in acute kidney injury: Report and summary of recommendations from the 10th Acute Dialysis Quality Initiative consensus conference. Kidney Int 2014; 85: 513-521
11. Haase M, Kellum JA, Ronco C: Subclinical AKI-an emerging syndrome with important consequences. Nat Rev Nephrol 2012; 8: 735-739
12. KDIGO AKI Work Group: KDIGO clinical practice guideline for acute kidney injury. Kidney Int Suppl 2012; 17: 1-138
13. Price PM, Safirstein RL, Megyesi J: The cell cycle and acute kidney injury. Kidney Int 2009; 76: 604-613
14. Boonstra J, Post JA: Molecular events associated with reactive oxygen species and cell cycle progression in mammalian cells. Gene 2004; 337: 1-13
15. Seo DW, Li H, Qu CK, et al: Shp-1 mediates the antiproliferative activity of tissue inhibitor of metalloproteinase-2 in human microvascular endothelial cells. J Biol Chem 2006; 281: 3711-3721
16. Rodier F, Campisi J, Bhaumik D: Two faces of p53: Aging and tumor suppression. Nucleic Acids Res 2007; 35: 7475-7484
17. Yang QH, Liu DW, Long Y, et al: Acute renal failure during sepsis: Potential role of cell cycle regulation. J Infect 2009; 58: 459-464
18. Seo DW, Li H, Guedez L, et al: TIMP-2 mediated inhibition of angiogenesis: An MMP-independent mechanism. Cell 2003; 114: 171-180
19. Kashani K, Al-Khafaji A, Ardiles T, et al: Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury. Crit Care 2013; 6: 17
20. Bihorac A, Chawla LS, Shaw AD, et al: Validation of cell-cycle arrest biomarkers for acute kidney injury using clinical adjudication. Am J Respir Crit Care Med 2014; 189: 932-939
21. Meersch M, Schmidt C, Van Aken H, et al: Urinary TIMP-2 and IGFBP7 as early biomarkers of acute kidney injury and renal recovery following cardiac surgery. PloS One 2014; 9: e93460
22. Nisula S, Yang R, Kaukonen KM, et al: FINNAKI Study Group: The urine protein NGAL predicts renal replacement therapy, but not acute kidney injury or 90-day mortality in critically ill adult patients. Anesth Analg 2014; 119: 95-102
23. Tu Y, Wang H, Sun R, et al: Urinary netrin-1 and KIM-1 as early biomarkers for septic acute kidney injury. Ren Fail 2014; 36: 1559-1563
24. Hoste EA, McCullough PA, Kashani K, et al: Sapphire Investigators: Derivation and validation of cutoffs for clinical use of cell cycle arrest biomarkers. Nephrol Dial Transplant 2014; 29: 2054-2061
25. Calandra T, Cohen J; International Sepsis Forum Definition of Infection in the ICU Consensus Conference: The international sepsis forum consensus conference on definitions of infection in the intensive care unit. Crit Care Med 2005; 33: 1538-1548
26. von Elm E, Altman DG, Egger M, et al: STROBE Initiative: The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: Guidelines for reporting observational studies. Ann Intern Med 2007; 147: 573-577
27. Bossuyt PM, Reitsma JB, Bruns DE, et al: STARD Group: Toward complete and accurate reporting of studies of diagnostic accuracy: The STARD initiative. Acad Radiol 2003; 10: 664-669
28. Knaus WA, LaRosa JC, Marks RD, et al: The value of commercial funding in health services research: The case of the APACHE III methodology. Health Serv Res 1994; 28: 673-678; discussion 683
29. Vincent JL, Moreno R, Takala J, et al: The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med 1996; 22: 707-710
30. Agresti A, Min Y: On small-sample confidence intervals for parameters in discrete distributions. Biometrics 2001; 57: 963-971
31. Core Team R: A language and environment for statistical computing. R Foundation for Statistical Computing. Vienna, Austria 2014. Available at: http: //wwwR-project. org/. Accessed August 10, 2015
32. Kellum JA, Chawla LS, Keener C, et al: The effects of alternative resuscitation strategies on acute kidney injury in patients with septic shock. Am J Resp Crit Care Med 2015; 193: 281-287
33. Peters E, Heemskerk S, Masereeuw R, et al: Alkaline phosphatase: A possible treatment for sepsis-associated acute kidney injury in critically ill patients. Am J Kidney Dis 2014; 63: 1038-1048
34. Honoré PM, Jacobs R, Boer W, et al: New insights regarding rationale, therapeutic target and dose of hemofiltration and hybrid therapies in septic acute kidney injury. Blood Purif 2012; 33: 44-51
35. Hoste EA, Bagshaw SM, Bellomo R, et al: Epidemiology of acute kidney injury in critically ill patients: The multinational AKI-EPI study. Intensive Care Med 2015; 41: 1411-1423
36. Mårtensson J, Bell M, Oldner A, et al: Neutrophil gelatinase-associated lipocalin in adult septic patients with and without acute kidney injury. Intensive Care Med 2010; 36: 1333-1340
37. Parikh CR, Abraham E, Ancukiewicz M, et al: Urine IL-18 is an early diagnostic marker for acute kidney injury and predicts mortality in the intensive care unit. J Am Soc Nephrol 2005; 16: 3046-3052
38. Dai X, Zeng Z, Fu C, et al: Diagnostic value of neutrophil gelatinase-associated lipocalin, cystatin C, and soluble triggering receptor expressed on myeloid cells-1 in critically ill patients with sepsis-associated acute kidney injury. Crit Care 2015; 19: 223
39. Wong HR, Cvijanovich NZ, Anas N, et al: A multibiomarker-based model for estimating the risk of septic acute kidney injury. Crit Care Med 2015; 43: 1646-1653
40. Bagshaw SM, Langenberg C, Haase M, et al: Urinary biomarkers in septic acute kidney injury. Intensive Care Med 2007; 33: 1285-1296
41. Honore PM, Jacobs R, Joannes-Boyau O, et al: Biomarkers for early diagnosis of AKI in the ICU: Ready for prime time use at the bedside? Ann Intensive Care 2012; 2: 24
42. Honore PM, Joannes-Boyau O, Boer W, et al: Acute kidney injury in the ICU: Time has come for an early biomarker kit! Acta Clin Belg 2007; 62(Suppl 2): 318-321
43. Zarbock A, Schmidt C, Van Aken H, et al: RenalRIPC Investigators: Effect of remote ischemic preconditioning on kidney injury among high-risk patients undergoing cardiac surgery: A randomized clinical trial. JAMA 2015; 313: 2133-2141
44. Zuo S, Liu C, Wang J, et al: IGFBP-rP1 induces p21 expression through a p53-independent pathway, leading to cellular senescence of MCF-7 breast cancer cells. J Cancer Res Clin Oncol 2012; 138: 1045-1055
45. Wajapeyee N, Serra RW, Zhu X, et al: Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7. Cell 2008; 132: 363-374
46. Zager RA: 'Biologic memory' in response to acute kidney injury: Cytoresistance, toll-like receptor hyper-responsiveness and the onset of progressive renal disease. Nephrol Dial Transplant 2013; 28: 1985-1993
47. Palud A, Parmentier-Decrucq E, Pastre J, et al: Evaluation of endothelial biomarkers as predictors of organ failures in septic shock patients. Cytokine 2015; 73: 213-218
48. Kellum JA, Bellomo R, Ronco C. Does this patient have acute kidney injury? An AKI checklist. Intensive Care Med 2015; 42: 96-99
49. Wilson FP, Shashaty M, Testani J, et al: Automated, electronic alerts for acute kidney injury: A single-blind, parallel-group, randomised controlled trial. Lancet 2015; 385: 1966-1974