Urinary TIMP-2 and IGFBP7 as early biomarkers of acute kidney injury and renal recovery following cardiac surgery

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Meersch, Melanie ^a   Schmidt, Christoph ^a   Van Aken, Hugo ^a   Martens, Sven ^a   Rossaint, Jan ^a   Singbartl, Kai ^b   Görlich, Dennis ^a   Kellum, John A ^c   Zarbock, Alexander ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; INSULIN LIKE GROWTH FACTOR BINDING PROTEIN 7; SOMATOMEDIN BINDING PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE 2; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED PROTEIN 1; TIMP2 PROTEIN, HUMAN;

ACUTE KIDNEY FAILURE; ADULT; ARTICLE; CARDIOPULMONARY BYPASS; CONVALESCENCE; CREATININE BLOOD LEVEL; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; DISEASE MARKER; EARLY DIAGNOSIS; FEMALE; HEART SURGERY; HIGH RISK PATIENT; HOSPITAL DISCHARGE; HUMAN; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; OLIGURIA; PREDICTION; PROGNOSIS; PROTEIN URINE LEVEL; RECEIVER OPERATING CHARACTERISTIC; RISK ASSESSMENT; RISK FACTOR; SENSITIVITY AND SPECIFICITY; SURGICAL RISK; URINALYSIS; ACUTE KIDNEY INJURY; ADVERSE EFFECTS; AGED; AREA UNDER THE CURVE; BLOOD; CLINICAL TRIAL; COMPLICATION; GENE EXPRESSION; GENETICS; HEART FAILURE; POSTOPERATIVE COMPLICATION; URINE; VERY ELDERLY;

ACUTE KIDNEY INJURY; AGED; AGED, 80 AND OVER; AREA UNDER CURVE; BIOLOGICAL MARKERS; CARDIOPULMONARY BYPASS; CREATININE; FEMALE; GENE EXPRESSION; HEART FAILURE; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS; MALE; POSTOPERATIVE COMPLICATIONS; PROGNOSIS; ROC CURVE; TISSUE INHIBITOR OF METALLOPROTEINASE-2;

EID: 84899840841     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0093460     Document Type: Article

References (40)

1. Wijeysundera DN, Karkouti K, Dupuis JY, Rao V, Chan CT, et al. (2007) Derivation and validation of a simplified predictive index for renal replacement therapy after cardiac surgery. JAMA 297: 1801-1809. (Pubitemid 46658649)
2. Chertow GM, Levy EM, Hammermeister KE, Grover F, Daley J (1998) Independent association between acute renal failure and mortality following cardiac surgery. Am J Med 104: 343-348. (Pubitemid 28211024)
3. Mangano CM, Diamondstone LS, Ramsay JG, Aggarwal A, Herskowitz A, et al. (1998) Renal dysfunction after myocardial revascularization: risk factors, adverse outcomes, and hospital resource utilization. The Multicenter Study of Perioperative Ischemia Research Group. Ann Intern Med 128: 194-203. (Pubitemid 28078200)
4. Zanardo G, Michielon P, Paccagnella A, Rosi P, Calo M, et al. (1994) Acute renal failure in the patient undergoing cardiac operation. Prevalence, mortality rate, and main risk factors. J Thorac Cardiovasc Surg 107: 1489-1495. (Pubitemid 24184992)
5. Lassnigg A, Schmidlin D, Mouhieddine M, Bachmann LM, Druml W, et al. (2004) Minimal changes of serum creatinine predict prognosis in patients after cardiothoracic surgery: a prospective cohort study. J Am Soc Nephrol 15: 1597-1605. (Pubitemid 38679685)
6. Rosner MH, Okusa MD (2006) Acute kidney injury associated with cardiac surgery. Clin J Am Soc Nephrol 1: 19-32.
7. Mehta RH, Grab JD, O'Brien SM, Bridges CR, Gammie JS, et al. (2006) Bedside tool for predicting the risk of postoperative dialysis in patients undergoing cardiac surgery. Circulation 114: 2208-2216; quiz 2208.
8. Thakar CV, Arrigain S, Worley S, Yared JP, Paganini EP (2005) A clinical score to predict acute renal failure after cardiac surgery. J Am Soc Nephrol 16: 162-168. (Pubitemid 43073168)
9. Bellomo R, Kellum JA, Ronco C (2004) Defining acute renal failure: physiological principles. Intensive Care Med 30: 33-37. (Pubitemid 38147105)
10. Murray PT, Le Gall JR, Dos Reis Miranda D, Pinsky MR, Tetta C (2002) Physiologic endpoints (efficacy) for acute renal failure studies. Curr Opin Crit Care 8: 519-525. (Pubitemid 35388206)
11. Wagener G, Jan M, Kim M, Mori K, Barasch JM, et al. (2006) Association between increases in urinary neutrophil gelatinase-associated lipocalin and acute renal dysfunction after adult cardiac surgery. Anesthesiology 105: 485-491. (Pubitemid 44310430)
12. Tang IY, Murray PT (2004) Prevention of perioperative acute renal failure: what works? Best Pract Res Clin Anaesthesiol 18: 91-111. (Pubitemid 38949987)
13. Melnikov VY, Faubel S, Siegmund B, Lucia MS, Ljubanovic D, et al. (2002) Neutrophil-independent mechanisms of caspase-1- and IL-18-mediated ischemic acute tubular necrosis in mice. J Clin Invest 110: 1083-1091. (Pubitemid 35215889)
14. Mishra J, Ma Q, Prada A, Mitsnefes M, Zahedi K, et al. (2003) Identification of neutrophil gelatinase-associated lipocalin as a novel early urinary biomarker for ischemic renal injury. J Am Soc Nephrol 14: 2534-2543. (Pubitemid 37169339)
15. Koyner JL, Bennett MR, Worcester EM, Ma Q, Raman J, et al. (2008) Urinary cystatin C as an early biomarker of acute kidney injury following adult cardiothoracic surgery. Kidney Int 74: 1059-1069.
16. Han WK, Bailly V, Abichandani R, Thadhani R, Bonventre JV (2002) Kidney Injury Molecule-1 (KIM-1): a novel biomarker for human renal proximal tubule injury. Kidney Int 62: 237-244. (Pubitemid 34754067)
17. Han WK, Wagener G, Zhu Y, Wang S, Lee HT (2009) Urinary biomarkers in the early detection of acute kidney injury after cardiac surgery. Clin J Am Soc Nephrol 4: 873-882.
18. Witzgall R, Brown D, Schwarz C, Bonventre JV (1994) Localization of proliferating cell nuclear antigen, vimentin, c-Fos, and clusterin in the postischemic kidney. Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells. J Clin Invest 93: 2175-2188.
19. Yang QH, Liu DW, Long Y, Liu HZ, Chai WZ, et al. (2009) Acute renal failure during sepsis: potential role of cell cycle regulation. J Infect 58: 459-464.
20. Devarajan P (2006) Update on mechanisms of ischemic acute kidney injury. J Am Soc Nephrol 17: 1503-1520.
21. Rodier F, Campisi J, Bhaumik D (2007) Two faces of p53: aging and tumor suppression. Nucleic Acids Res 35: 7475-7484.
22. Boonstra J, Post JA (2004) Molecular events associated with reactive oxygen species and cell cycle progression in mammalian cells. Gene 337: 1-13. (Pubitemid 38970100)
23. Kashani K, Al-Khafaji A, Ardiles T, Artigas A, Bagshaw SM, et al. (2013) Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury. Crit Care 17: R25.
24. Bossuyt PM, Reitsma JB, Bruns DE, Gatsonis CA, Glasziou PP, et al. (2003) Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. BMJ 326: 41-44. (Pubitemid 36110721)
25. Bellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P (2004) Acute renal failure - definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care 8: R204-212.
26. Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, et al. (2007) Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care 11: R31.
27. (2012) KDIGO AKI Work Group: KDIGO clinical practice guideline for acute kidney injury. Kidney Int Suppl 2: 1-138.
28. Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, et al. (1999) A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med 130: 461-470. (Pubitemid 29135798)
29. Pencina MJ, D'Agostino RB Sr., Steyerberg EW (2011) Extensions of net reclassification improvement calculations to measure usefulness of new biomarkers. Stat Med 30: 11-21.
30. Kundu S, Aulchenko YS, van Duijn CM, Janssens AC (2011) PredictABEL: an R package for the assessment of risk prediction models. Eur J Epidemiol 26: 261-264.
31. Smertka M, Chudek J (2012) Using NGAL as an early diagnostic test of acute kidney injury. Ren Fail 34: 130-133.
32. Palevsky PM, Zhang JH, O'Connor TZ, Chertow GM, Crowley ST, et al. (2008) Intensity of renal support in critically ill patients with acute kidney injury. N Engl J Med 359: 7-20. (Pubitemid 351931092)
33. Uchino S, Kellum JA, Bellomo R, Doig GS, Morimatsu H, et al. (2005) Acute renal failure in critically ill patients: a multinational, multicenter study. Jama 294: 813-818. (Pubitemid 41175724)
34. Manns B, Doig CJ, Lee H, Dean S, Tonelli M, et al. (2003) Cost of acute renal failure requiring dialysis in the intensive care unit: clinical and resource implications of renal recovery. Crit Care Med 31: 449-455. (Pubitemid 36232939)
35. Srisawat N, Murugan R, Lee M, Kong L, Carter M, et al. (2011) Plasma neutrophil gelatinase-associated lipocalin predicts recovery from acute kidney injury following community-acquired pneumonia. Kidney Int 80: 545-552.
36. Srisawat N, Wen X, Lee M, Kong L, Elder M, et al. (2011) Urinary biomarkers and renal recovery in critically ill patients with renal support. Clin J Am Soc Nephrol 6: 1815-1823.
37. Bonventre JV, Yang L (2011) Cellular pathophysiology of ischemic acute kidney injury. J Clin Invest 121: 4210-4221.
38. Price PM, Safirstein RL, Megyesi J (2009) The cell cycle and acute kidney injury. Kidney Int 76: 604-613.
39. Waikar SS, Sabbisetti VS, Bonventre JV (2010) Normalization of urinary biomarkers to creatinine during changes in glomerular filtration rate. Kidney Int 78: 486-494.
40. Mishra J, Dent C, Tarabishi R, Mitsnefes MM, Ma Q, et al. (2005) Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery. Lancet 365: 1231-1238. (Pubitemid 40469655)