Validation of cell-cycle arrest biomarkers for acute kidney injury using clinical adjudication

American Journal of Respiratory and Critical Care Medicine

Volumn 189, Issue 8, 2014, Pages 932-939

  Bihorac, Azra ^a   Chawla, Lakhmir S ^b   Shaw, Andrew D ^c   Al Khafaji, Ali ^d   Davison, Danielle L ^b   DeMuth, George E ^e   Fitzgerald, Robert ^f   Gong, Michelle Ng ^g   Graham, Derrel D ^h   Gunnerson, Kyle ^i,j   Heung, Michael ^k   Jortani, Saeed ^l   Kleerup, Eric ^m   Koyner, Jay L ⁿ   Krell, Kenneth ^o   LeTourneau, Jennifer ^p   Lissauer, Matthew ^q   Miner, James ^r   Nguyen, H Bryant ^s   Ortega, Luis M ⁱ   Self, Wesley H ^t   Sellman, Richard ^u   Shi, Jing ^v   Straseski, Joely ^w   Szalados, James E ^x   Wilber, Scott T ^y   Walker, Michael G ^v   Wilson, Jason ^z   Wunderink, Richard ^aa   Zimmerman, Janice ^ab   Kellum, John A ^ac   more..

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^d UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^e Stat Tech Services   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g MONTEFIORE MEDICAL CENTER   (United States)

^h LOUISIANA STATE UNIVERSITY   (United States)

ⁱ Department of Anesthesiology ^*  (United States)

^j VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^k UNIVERSITY OF MICHIGAN   (United States)

^l University of Louisville School of Medicine   (United States)

^m UNIVERSITY OF CALIFORNIA   (United States)

ⁿ UNIVERSITY OF CHICAGO   (United States)

^o Eastern Idaho Medical Center   (United States)

^p PORTLAND VA MEDICAL CENTER   (United States)

^q UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^r HENNEPIN COUNTY MEDICAL CENTER   (United States)

^s LOMA LINDA UNIVERSITY   (United States)

^t VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^u International Heart Institute Montana   (United States)

^v Kelly Statistical Consulting   (United States)

^w UNIVERSITY OF UTAH   (United States)

^x Rochester General Research Institute   (United States)

^y SUMMA HEALTH SYSTEM   (United States)

^z TAMPA GENERAL HOSPITAL   (United States)

^aa NORTHWESTERN UNIVERSITY   (United States)

^ab HOUSTON METHODIST HOSPITAL   (United States)

^ac UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

more..

Author keywords

Acute kidney injury; Biomarkers; Cell cycle arrest; Insulin like growth factor binding protein 7; Tissue inhibitor of metalloproteinases 2

Indexed keywords

ACUTE KIDNEY INJURY; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; CELL DEATH; COHORT STUDIES; CRITICAL ILLNESS; FEMALE; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; PROTEASE INHIBITORS; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; TIME FACTORS; TISSUE INHIBITOR OF METALLOPROTEINASE-2; UNITED STATES;

EID: 84899023880     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201401-0077OC     Document Type: Article

References (37)

1. Bihorac A, Brennan M, Ozrazgat-Baslanti T, Bozorgmehri S, Efron PA, Moore FA, Segal MS, Hobson CE. National surgical quality improvement program underestimates the risk associated with mild and moderate postoperative acute kidney injury. Crit Care Med 2013;41:2570-2583.
2. Bihorac A, Yavas S, Subbiah S, Hobson CE, Schold JD, Gabrielli A, Layon AJ, Segal MS. Long-term risk of mortality and acute kidney injury during hospitalization after major surgery. Ann Surg 2009;249:851-858.
3. Chawla LS, Amdur RL, Amodeo S, Kimmel PL, Palant CE. The severity of acute kidney injury predicts progression to chronic kidney disease. Kidney Int 2011;79:1361-1369.
4. Chertow GM, Burdick E, Honour M, Bonventre JV, Bates DW. Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol 2005;16:3365-3370.
5. Kashani K, Al-Khafaji A, Ardiles T, Artigas A, Bagshaw SM, Bell M, Bihorac A, Birkhahn R, Cely CM, Chawla LS, et al. Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury. Crit Care 2013;17:R25.
6. Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group. KDIGO clinical practice guideline for acute kidney injury. Kidney Int Suppl 2012;2:1-138.
7. Koyner JL, Shaw A, Chawla LS, Hoste EAJ, Bihorac A, Kahsani K, Shi J, Kellum JA. Increased TIMP2-IGFBP7 is associated with increased 9 month mortality in ICU patients at risk for AKI. Paper presented at the American Society of Nephrology, November 7-10, 2013, Atlanta, GA.
8. Palevsky PM, Liu KD, Brophy PD, Chawla LS, Parikh CR, Thakar CV, Tolwani AJ, Waikar SS, Weisbord SD. KDOQI US commentary on the 2012 KDIGO clinical practice guideline for acute kidney injury. Am J Kidney Dis 2013;61:649-672.
9. Vincent JL, Moreno R, Takala J, Willatts S, De Mendonça A, Bruining H, Reinhart CK, Suter PM, Thijs LG; Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. Intensive Care Med 1996;22:707-710.
10. R Development Core Team. R: a language and environment for statistical computing. R Foundation for Statistical Computing: Vienna, Austria; 2011 [accessed 2013 Oct 26]. Available from: http://www.R-project.org/
11. Zhou X-H, Obuchowski N, McClish DK. Statistical methods in diagnostic medicine. New York: John Wiley & Sons, Inc; 2002.
12. von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, Vandenbroucke JP; STROBE Initiative. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Ann Intern Med 2007;147:573-577.
13. Bossuyt PM, Reitsma JB, Bruns DE, Gatsonis CA, Glasziou PP, Irwig LM, Lijmer JG, Moher D, Rennie D, de Vet HC; STARD Group. Toward complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. Acad Radiol 2003;10: 664-669.
14. Maisel AS, Krishnaswamy P, Nowak RM, McCord J, Hollander JE, Duc P, Omland T, Storrow AB, Abraham WT, Wu AH, et al.; Breathing Not Properly Multinational Study Investigators. Rapid measurement of Btype natriuretic peptide in the emergency diagnosis of heart failure. N Engl J Med 2002;347:161-167.
15. Keller T, Zeller T, Peetz D, Tzikas S, Roth A, Czyz E, Bickel C, Baldus S, Warnholtz A, Frohlich M, et al. Sensitive troponin I assay in early diagnosis of acute myocardial infarction. N Engl J Med 2009;361: 868-877.
16. Wilson PW, D'Agostino RB, Levy D, Belanger AM, Silbershatz H, Kannel WB. Prediction of coronary heart disease using risk factor categories. Circulation 1998;97:1837-1847.
17. Khot UN, KhotMB, Bajzer CT, Sapp SK, Ohman EM, Brener SJ, Ellis SG, Lincoff AM, Topol EJ. Prevalence of conventional risk factors in patients with coronary heart disease. JAMA 2003;290:898-904.
18. Ford ES, Giles WH, Mokdad AH. The distribution of 10-Year risk for coronary heart disease among US adults: findings from the National Health and Nutrition Examination Survey III. J Am Coll Cardiol 2004;43: 1791-1796.
19. Mosca L, Linfante AH, Benjamin EJ, Berra K, Hayes SN, Walsh BW, Fabunmi RP, Kwan J, Mills T, Simpson SL. National study of physician awareness and adherence to cardiovascular disease prevention guidelines. Circulation 2005;111:499-510.
20. Montgomery AA, Fahey T, MacKintosh C, Sharp DJ, Peters TJ. Estimation of cardiovascular risk in hypertensive patients in primary care. Br J Gen Pract 2000;50:127-128.
21. Cross DS, McCarty CA, Hytopoulos E, Beggs M, Nolan N, Harrington DS, Hastie T, Tibshirani R, Tracy RP, Psaty BM, et al. Coronary risk assessment among intermediate risk patients using a clinical and biomarker based algorithm developed and validated in two population cohorts. Curr Med Res Opin 2012;28: 1819-1830.
22. Solomon MD, Tirupsur A, Hytopoulos E, Beggs M, Harrington DS, French C, Quertermous T. Clinical utility of a novel coronary heart disease riskassessment test to further classify intermediate-risk patients. Clin Cardiol 2013;36:621-627.
23. Lilly CM, Zuckerman IH, Badawi O, Riker RR. Benchmark data from more than 240,000 adults that reflect the current practice of critical care in the United States. Chest 2011;140:1232-1242.
24. Lameire NH, Bagga A, Cruz D, De Maeseneer J, Endre Z, Kellum JA, Liu KD, Mehta RL, Pannu N, Van Biesen W, et al. Acute kidney injury: an increasing global concern. Lancet 2013;382:170-179.
25. Palevsky PM, Molitoris BA, Okusa MD, Levin A, Waikar SS, Wald R, Chertow GM, Murray PT, Parikh CR, Shaw AD, et al. Design of clinical trials in acute kidney injury: report from an NIDDK workshop on trial methodology. Clin J Am Soc Nephrol 2012;7:844-850.
26. MolitorisBA, OkusaMD, Palevsky PM, Chawla LS, Kaufman JS, Devarajan P, TotoRM, HsuCY, Greene TH, Faubel SG, et al. Design of clinical trials in AKI: a report from an NIDDK workshop. Trials of patients with sepsis and in selected hospital settings. Clin J Am Soc Nephrol 2012;7: 856-860.
27. Okusa MD, Molitoris BA, Palevsky PM, Chinchilli VM, Liu KD, Cheung AK, Weisbord SD, Faubel S, Kellum JA, Wald R, et al. Design of clinical trials in acute kidney injury: a report from an NIDDK workshop- prevention trials. Clin J Am Soc Nephrol 2012;7:851-855.
28. O'Gara PT, Kushner FG, Ascheim DD, Casey DE Jr., Chung MK, de Lemos JA, Ettinger SM, Fang JC, Fesmire FM, Franklin BA, et al.; American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation 2013;127:e362-e425.
29. Jauch EC, Saver JL, Adams HP Jr., Bruno A, Connors JJ, Demaerschalk BM, Khatri P, McMullan PWJr., Qureshi AI, Rosenfield K, et al.; American Heart Association Stroke Council; Council on Cardiovascular Nursing; Council on Peripheral Vascular Disease; Council on Clinical Cardiology. Guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2013;44:870-947.
30. Chovanes J, Cannon JW, Nunez TC. The evolution of damage control surgery. Surg Clin North Am 2012;92:859-875, vii-viii. 31. NCEPOD. Adding insult to injury. 2009 [accessed 2013 Aug 5]. Available from: http://www.ncepod.org.uk/ 2009aki.htm
31. Ishani A, Xue JL, Himmelfarb J, Eggers PW, Kimmel PL, Molitoris BA, Collins AJ. Acute kidney injury increases risk of ESRD among elderly. J Am Soc Nephrol 2009;20:223-228.
32. Hsu RK, McCulloch CE, Dudley RA, Lo LJ, Hsu CY. Temporal changes in incidence of dialysis-requiring AKI. J Am Soc Nephrol 2013;24:37-42.
33. Ishani A, NelsonD, ClothierB, Schult T,Nugent S,GreerN, SlininY, Ensrud KE. The magnitude of acute serum creatinine increase after cardiac surgery and the risk of chronic kidney disease, progression of kidney disease, and death. Arch Intern Med 2011;171:226-233.
34. Nisula S, Kaukonen KM, Vaara ST, Korhonen AM, Poukkanen M, Karlsson S, Haapio M, Inkinen O, Parviainen I, Suojaranta-Ylinen R, et al.; FINNAKI Study Group. Incidence, risk factors and 90-day mortality of patients with acute kidney injury in Finnish intensive care units: the FINNAKI study. Intensive Care Med 2013;39:420-428.
35. Bagshaw SM, Uchino S, Bellomo R, Morimatsu H, Morgera S, Schetz M, Tan I, Bouman C, Macedo E, Gibney N, et al.; Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators. Septic acute kidney injury in critically ill patients: clinical characteristics and outcomes. Clin J Am Soc Nephrol 2007;2:431-439.
36. Bagshaw SM, George C, Bellomo R; ANZICS Database Management Committee. Early acute kidney injury and sepsis: a multicentre evaluation. Crit Care 2008;12:R47.
37. Finlay S, Bray B, Lewington AJ, Hunter-Rowe CT, Banerjee A, Atkinson JM, Jones MC. Identification of risk factors associated with acute kidney injury in patients admitted to acute medical units. Clin Med 2013;13: 233-238.