Interleukin-6 induces impairment in human subcutaneous adipogenesis in obesity-associated insulin resistance

Diabetologia

Volumn 59, Issue 11, 2016, Pages 2406-2416

  Almuraikhy, Shamma ^a,b   Kafienah, Wael ^b   Bashah, Moataz ^c   Diboun, Ilhame ^d   Jaganjac, Morana ^a   Al Khelaifi, Fatima ^a   Abdesselem, Houari ^d   Mazloum, Nayef A ^d   Alsayrafi, Mohammed ^a   Mohamed Ali, Vidya ^a   Elrayess, Mohamed A ^a  

^a Anti Doping Lab Qatar ^*  (Qatar)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c HAMAD MEDICAL CORPORATION   (Qatar)

^d WEILL CORNELL MEDICAL COLLEGE   (Qatar)

Author keywords

Adipogenesis; Insulin resistance; Insulin sensitivity; Interleukin 6; Obesity; Subcutaneous fat; Type 2 diabetes mellitus

Indexed keywords

5' NUCLEOTIDASE; ACTIVATED LEUKOCYTE CELL ADHESION MOLECULE; ADIPONECTIN; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CCAAT ENHANCER BINDING PROTEIN ALPHA; CD11B ANTIGEN; CD31 ANTIGEN; CD45 ANTIGEN; CELL SURFACE MARKER; DNA FORMAMIDOPYRIMIDINE GLYCOSYLASE; ENDOGLIN; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LEPTIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; METFORMIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRANSCRIPTION FACTOR GATA 3; TRIACYLGLYCEROL; ADIPOQ PROTEIN, HUMAN; GATA3 PROTEIN, HUMAN; IL6 PROTEIN, HUMAN;

ADIPOCYTE; ADIPOGENESIS; ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANTIGEN EXPRESSION; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CELL DIFFERENTIATION; CELL HYPERPLASIA; CELL ISOLATION; CELL PLASTICITY; CELL SIZE; CELL VIABILITY; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE ASSOCIATION; DOWN REGULATION; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERINSULINEMIA; IN VITRO STUDY; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN TREATMENT; LONG TERM EXPOSURE; MAJOR CLINICAL STUDY; MALE; MOLECULAR MECHANICS; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RISK FACTOR; SUBCUTANEOUS FAT; TRIACYLGLYCEROL BLOOD LEVEL; UPREGULATION; WEIGHT REDUCTION; GENETICS; METABOLISM; MIDDLE AGED; PHYSIOLOGY;

ADIPOCYTES; ADIPOGENESIS; ADIPONECTIN; ADULT; DIABETES MELLITUS, TYPE 2; FEMALE; GATA3 TRANSCRIPTION FACTOR; HUMANS; IN VITRO TECHNIQUES; INSULIN RESISTANCE; INTERLEUKIN-6; MALE; MIDDLE AGED; OBESITY; PPAR GAMMA;

EID: 84976351836     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-016-4031-3     Document Type: Article

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