Model predicts that MKP1 and TAB1 Regulate p38α Nuclear pulse and its basal activity through positive and negative feedback loops in response to IL-1

PLoS ONE

Volumn 11, Issue 6, 2016, Pages

  Singh, Raghvendra ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY KANPUR   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; INTERLEUKIN 1; MITOGEN ACTIVATED PROTEIN KINASE 14; MITOGEN ACTIVATED PROTEIN KINASE KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 6; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; TAB1 PROTEIN; UNCLASSIFIED DRUG; MAP2K3 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TAB1 PROTEIN, HUMAN;

ARTICLE; CELL MEMBRANE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CYTOPLASM; MATHEMATICAL MODEL; NEGATIVE FEEDBACK; POSITIVE FEEDBACK; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; BIOSYNTHESIS; CELL JUNCTION; CELL MOTION; CELL NUCLEUS MEMBRANE; ENZYME ACTIVATION; ENZYMOLOGY; GENETICS; HUMAN; INFLAMMATION; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGICAL FEEDBACK; PHYSIOLOGICAL STRESS; THEORETICAL MODEL;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; CELL MOVEMENT; CYTOPLASM; ENZYME ACTIVATION; FEEDBACK, PHYSIOLOGICAL; HUMANS; INFLAMMATION; INTERCELLULAR JUNCTIONS; MAP KINASE KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE PHOSPHATASES; MODELS, THEORETICAL; NUCLEAR ENVELOPE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL;

EID: 84976321279     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0157572     Document Type: Article

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