메뉴 건너뛰기




Volumn 2, Issue AUG, 2014, Pages

Ascorbic acid is a dose-dependent inhibitor of adipocyte differentiation, probably by reducing cAMP pool

Author keywords

Adipocytes; Ascorbic acid; Cell differentiation; Cyclic AMP

Indexed keywords


EID: 84975891023     PISSN: None     EISSN: 2296634X     Source Type: Journal    
DOI: 10.3389/fcell.2014.00029     Document Type: Article
Times cited : (22)

References (35)
  • 2
    • 84860475014 scopus 로고    scopus 로고
    • Antiproliferative effect of ascorbic acid is associated with the inhibition of genes necessary to cell cycle progression
    • Belin, S., Kaya, F., Duisit, G., Giacometti, S., Ciccolini, J., and Fontés, M. (2009). Antiproliferative effect of ascorbic acid is associated with the inhibition of genes necessary to cell cycle progression. PLoS ONE 4:e4409. doi: 10.1371/journal.pone.0004409
    • (2009) PLoS ONE , vol.4
    • Belin, S.1    Kaya, F.2    Duisit, G.3    Giacometti, S.4    Ciccolini, J.5    Fontés, M.6
  • 3
    • 77949902266 scopus 로고    scopus 로고
    • Down-regulation of tissue inhibitor of metalloproteinase-3 (TIMP-3) expression is necessary for adipocyte differentiation
    • Bernot, D., Barruet, E., Poggi, M., Bonardo, B., Alessi, M. C., and Peiretti, F. (2010). Down-regulation of tissue inhibitor of metalloproteinase-3 (TIMP-3) expression is necessary for adipocyte differentiation. J. Biol. Chem. 285, 6508-6514. doi: 10.1074/jbc. M109.078444
    • (2010) J. Biol. Chem. , vol.285 , pp. 6508-6514
    • Bernot, D.1    Barruet, E.2    Poggi, M.3    Bonardo, B.4    Alessi, M.C.5    Peiretti, F.6
  • 5
    • 33845520528 scopus 로고    scopus 로고
    • Diferential gene expression and adiposity reduction induced by ascorbic acid supplementation in a cafeteria model of obesity
    • Campión, J., Milagro, F. I., Fernández, D., and Martínez, J. A. (2006). Diferential gene expression and adiposity reduction induced by ascorbic acid supplementation in a cafeteria model of obesity. J. Physiol. Biochem, 62, 71-80. doi: 10.1007/BF03174068
    • (2006) J. Physiol. Biochem , vol.62 , pp. 71-80
    • Campión, J.1    Milagro, F.I.2    Fernández, D.3    Martínez, J.A.4
  • 6
    • 33644684441 scopus 로고    scopus 로고
    • Plasma ascorbic acid concentrations and fat distribution in 19,068 British men and women in the European Prospective Investigation into Cancer and Nutrition Norfolk cohort study
    • Canoy, D., Wareham, N., Welch, A., Bingham, S., Luben, R., Day, N., et al. (2005). Plasma ascorbic acid concentrations and fat distribution in 19,068 British men and women in the European Prospective Investigation into Cancer and Nutrition Norfolk cohort study. Am. J. Clin. Nutr. 82, 1203-1209.
    • (2005) Am. J. Clin. Nutr. , vol.82 , pp. 1203-1209
    • Canoy, D.1    Wareham, N.2    Welch, A.3    Bingham, S.4    Luben, R.5    Day, N.6
  • 7
    • 47149090214 scopus 로고    scopus 로고
    • Effect of ascorbic acid on bone marrow-derived mesenchymal stem cell proliferation and differentiation
    • Choi, K. M., Seo, Y. K., Yoon, H. H., Song, K. Y., Kwon, S. Y., Lee, H. S., et al. (2008). Effect of ascorbic acid on bone marrow-derived mesenchymal stem cell proliferation and differentiation. J. Biosci. Bioeng. 105, 586-594. doi: 10.1263/jbb.105.586
    • (2008) J. Biosci. Bioeng. , vol.105 , pp. 586-594
    • Choi, K.M.1    Seo, Y.K.2    Yoon, H.H.3    Song, K.Y.4    Kwon, S.Y.5    Lee, H.S.6
  • 8
    • 77955067688 scopus 로고    scopus 로고
    • Characterization of OP9 as authentic mesenchymal stem cell line
    • Gao, J., Yan, X-L., Li, R., Liu, Y., He, W., Sun, S., et al. (2010). Characterization of OP9 as authentic mesenchymal stem cell line. J. Genet. Genomics. 37, 475-482. doi: 10.1016/S1673-8527(09)60067-9
    • (2010) J. Genet. Genomics. , vol.37 , pp. 475-482
    • Gao, J.1    Yan, X-L.2    Li, R.3    Liu, Y.4    He, W.5    Sun, S.6
  • 9
    • 81855196123 scopus 로고    scopus 로고
    • Sodium-dependent vitamin C transporter 2 deficiency causes hypomyelination and extracellular matrix defects in the peripheral nervous system
    • Gess, B., Röhr, D., Fledrich, R., Sereda, M. W., Kleffner, I., Humberg, A., et al. (2011). Sodium-dependent vitamin C transporter 2 deficiency causes hypomyelination and extracellular matrix defects in the peripheral nervous system. J. Neurosci. 31, 17180-17192. doi: 10.1523/JNEUROSCI.3457-11.2011
    • (2011) J. Neurosci. , vol.31 , pp. 17180-17192
    • Gess, B.1    Röhr, D.2    Fledrich, R.3    Sereda, M.W.4    Kleffner, I.5    Humberg, A.6
  • 10
    • 84884213220 scopus 로고    scopus 로고
    • SVCT-2 in breast cancer acts as an indicator for L-ascorbate treatment
    • Hong, S. W., Lee, S. H., Moon, J. H., Hwang, J. J., Kim, D. E., Ko, E., et al. (2013). SVCT-2 in breast cancer acts as an indicator for L-ascorbate treatment. Oncology 32, 1508-1517. doi: 10.1038/onc.2012.176
    • (2013) Oncology , vol.32 , pp. 1508-1517
    • Hong, S.W.1    Lee, S.H.2    Moon, J.H.3    Hwang, J.J.4    Kim, D.E.5    Ko, E.6
  • 11
    • 84858963829 scopus 로고    scopus 로고
    • Activation of protein kinase A and exchange protein directly activated by cAMP promotes adipocyte differentiation of human mesenchymal stem cells
    • Jia, B., Madsen, L., Petersen, R. K., Techer, N., Kopperud, R., Ma, T., et al. (2012). Activation of protein kinase A and exchange protein directly activated by cAMP promotes adipocyte differentiation of human mesenchymal stem cells. PLoS ONE 7:e34114. doi: 10.1371/journal.pone.0034114
    • (2012) PLoS ONE , vol.7
    • Jia, B.1    Madsen, L.2    Petersen, R.K.3    Techer, N.4    Kopperud, R.5    Ma, T.6
  • 12
    • 34447130852 scopus 로고    scopus 로고
    • Plasma vitamin C is inversely related to body mass index and waist circumference but not to plasma adiponectin in nonsmoking adults
    • Johnston, C. S., Beezhold, B. L., Mostow, B., and Swan, P. D. (2007). Plasma vitamin C is inversely related to body mass index and waist circumference but not to plasma adiponectin in nonsmoking adults. J. Nutr. 137, 1757-1762.
    • (2007) J. Nutr. , vol.137 , pp. 1757-1762
    • Johnston, C.S.1    Beezhold, B.L.2    Mostow, B.3    Swan, P.D.4
  • 13
    • 84868587300 scopus 로고    scopus 로고
    • Gene expression of mesoderm-specific transcript is upregulated as preadipocytes differentiate to adipocytes in vitro
    • Kadota, Y., Yanagawa, M., Nakaya, T., Kawakami, T., Sato, M., and Suzuki, S. (2012). Gene expression of mesoderm-specific transcript is upregulated as preadipocytes differentiate to adipocytes in vitro. J. Physiol. Sci. 62, 403-411. doi: 10.1007/s12576-012-0217-8
    • (2012) J. Physiol. Sci. , vol.62 , pp. 403-411
    • Kadota, Y.1    Yanagawa, M.2    Nakaya, T.3    Kawakami, T.4    Sato, M.5    Suzuki, S.6
  • 14
    • 84878244694 scopus 로고    scopus 로고
    • Cyclic AMP signaling in bone marrow stromal cells has reciprocal effects on the ability of mesenchymal stem cells to differentiate into mature osteoblasts versus mature adipocytes
    • Kao, R., Lu, W., Louie, A., and Nissenson, R. (2012). Cyclic AMP signaling in bone marrow stromal cells has reciprocal effects on the ability of mesenchymal stem cells to differentiate into mature osteoblasts versus mature adipocytes. Endocrine 42, 622-636. doi: 10.1007/s12020-012-9717-9
    • (2012) Endocrine , vol.42 , pp. 622-636
    • Kao, R.1    Lu, W.2    Louie, A.3    Nissenson, R.4
  • 15
    • 33947219362 scopus 로고    scopus 로고
    • Ascorbic acid inhibits PMP22 expression by reducing cAMP levels
    • Kaya, F., Belin, S., Bourgeois, P., Micaleff, J., Blin, O., and Fontés, M. (2007). Ascorbic acid inhibits PMP22 expression by reducing cAMP levels. Neuromuscul. Disord. 17, 248-253. doi: 10.1016/j.nmd.2006.12.008
    • (2007) Neuromuscul. Disord. , vol.17 , pp. 248-253
    • Kaya, F.1    Belin, S.2    Bourgeois, P.3    Micaleff, J.4    Blin, O.5    Fontés, M.6
  • 16
    • 53949085980 scopus 로고    scopus 로고
    • Ascorbic acid is a regulator of the intracellular cAMP concentration: old molecule, new functions?
    • Kaya, F., Belin, S., Diamantidis, G., and Fontes, M. (2008a). Ascorbic acid is a regulator of the intracellular cAMP concentration: old molecule, new functions? FEBS Lett. 582, 3614-3618. doi: 10.1016/j.febslet.2008.09.040
    • (2008) FEBS Lett. , vol.582 , pp. 3614-3618
    • Kaya, F.1    Belin, S.2    Diamantidis, G.3    Fontes, M.4
  • 17
    • 49449094807 scopus 로고    scopus 로고
    • Analysis of the benefits of vitamin cocktails in treating Charcot-Marie-Tooth disease type 1A
    • Kaya, F., Belin, S., Micallef, J., Blin, O., and Fontés, M. (2008b). Analysis of the benefits of vitamin cocktails in treating Charcot-Marie-Tooth disease type 1A. Muscle Nerve 38, 1052-1054. doi: 10.1002/mus.21071
    • (2008) Muscle Nerve , vol.38 , pp. 1052-1054
    • Kaya, F.1    Belin, S.2    Micallef, J.3    Blin, O.4    Fontés, M.5
  • 18
    • 0030007427 scopus 로고    scopus 로고
    • ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism
    • Kim, J. B., and Spiegelman, B. M. (1996). ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism. Genes 10, 1096-1107. doi: 10.1101/gad.10.9.1096
    • (1996) Genes , vol.10 , pp. 1096-1107
    • Kim, J.B.1    Spiegelman, B.M.2
  • 19
    • 73149116408 scopus 로고    scopus 로고
    • cAMP-response element binding protein (CREB) positively regulates mouse adiponectin gene expression in 3T3-L1 adipocytes
    • Kim, W. H., Han, K. L., Park, J. H., Lee, J., Yeo, J., and Jung, M. H. (2010). cAMP-response element binding protein (CREB) positively regulates mouse adiponectin gene expression in 3T3-L1 adipocytes. Biochem. Biophys. Res. Commun. 391, 634-639. doi: 10.1016/j.bbrc.2009.11.111
    • (2010) Biochem. Biophys. Res. Commun. , vol.391 , pp. 634-639
    • Kim, W.H.1    Han, K.L.2    Park, J.H.3    Lee, J.4    Yeo, J.5    Jung, M.H.6
  • 22
    • 77953503328 scopus 로고    scopus 로고
    • A chromatin perspective of adipogenesis
    • Musri, M. M., Gomis, R., and Párrizas, M. (2010). A chromatin perspective of adipogenesis. Organogenesis 6, 15-23. doi: 10.4161/org.6.1.10226
    • (2010) Organogenesis , vol.6 , pp. 15-23
    • Musri, M.M.1    Gomis, R.2    Párrizas, M.3
  • 23
    • 0025364016 scopus 로고
    • Ascorbic acid phosphate stimulates type IV collagen synthesis and accelerates adipose conversion of 3T3-L1 cells
    • Ono, M., Aratani, Y., Kitagawa, I., and Kitagawa, Y. (1990). Ascorbic acid phosphate stimulates type IV collagen synthesis and accelerates adipose conversion of 3T3-L1 cells. Exp. Cell. Res. 187, 309-314. doi: 10.1016/0014-4827(90)90096-S
    • (1990) Exp. Cell. Res. , vol.187 , pp. 309-314
    • Ono, M.1    Aratani, Y.2    Kitagawa, I.3    Kitagawa, Y.4
  • 24
    • 1942422646 scopus 로고    scopus 로고
    • Ascorbic acid treatment corrects the phenotype of a mouse model of Charcot-Marie-Tooth disease
    • Passage, E., Norreel, J. C., Noack-Fraissignes, P., Sanguedolce, V., Pizant, J., Thirion, X., et al. (2004). Ascorbic acid treatment corrects the phenotype of a mouse model of Charcot-Marie-Tooth disease. Nat. Med. 10, 396-401. doi: 10.1038/nm1023
    • (2004) Nat. Med. , vol.10 , pp. 396-401
    • Passage, E.1    Norreel, J.C.2    Noack-Fraissignes, P.3    Sanguedolce, V.4    Pizant, J.5    Thirion, X.6
  • 25
    • 0037326196 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator
    • Puigserver, P., and Spiegelman, B. M. (2003). Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator. Endocr. Rev. 24, 78-90. doi: 10.1210/er.2002-0012
    • (2003) Endocr. Rev. , vol.24 , pp. 78-90
    • Puigserver, P.1    Spiegelman, B.M.2
  • 26
    • 57349113916 scopus 로고    scopus 로고
    • Mechanisms and regulation of vitamin C uptake: studies of the hSVCT systems in human liver epithelial cells
    • Reidling, J. C., Subramanian, V. S., Dahhan, T., Sadat, M., and Said, H. M. (2008). Mechanisms and regulation of vitamin C uptake: studies of the hSVCT systems in human liver epithelial cells. Am. J. Gastrointest Liver Physiol. 295, 1217. doi: 10.1152/ajpgi.90399.2008
    • (2008) Am. J. Gastrointest Liver Physiol. , vol.295 , pp. 1217
    • Reidling, J.C.1    Subramanian, V.S.2    Dahhan, T.3    Sadat, M.4    Said, H.M.5
  • 27
    • 85047699109 scopus 로고    scopus 로고
    • Ascorbic-acid transporter Slc23a1 is essential for AA transport into the brain and for perinatal survival
    • Sotiriou, S., Gispert, S., Cheng, J., Wang, Y., Chen, A., Hoogstraten-Miller, S., et al. (2002). Ascorbic-acid transporter Slc23a1 is essential for AA transport into the brain and for perinatal survival. Nat. Med. 8, 514-517. doi: 10.1038/0502-514
    • (2002) Nat. Med. , vol.8 , pp. 514-517
    • Sotiriou, S.1    Gispert, S.2    Cheng, J.3    Wang, Y.4    Chen, A.5    Hoogstraten-Miller, S.6
  • 28
    • 0035936764 scopus 로고    scopus 로고
    • Obesity and the regulation of energy balance
    • Spiegelman, B. M., and Flier, J. S. (2001). Obesity and the regulation of energy balance. Cell 104, 531-543. doi: 10.1016/S0092-8674(01)00240-9
    • (2001) Cell , vol.104 , pp. 531-543
    • Spiegelman, B.M.1    Flier, J.S.2
  • 29
    • 0037446546 scopus 로고    scopus 로고
    • Ascorbic acid enhances differentiation of embryonic stem cells into cardiac myocytes
    • Takahashi, T., Lord, B., Schulze, P., Fryer, R., Sarang, S., Gullans, S., et al. (2003). Ascorbic acid enhances differentiation of embryonic stem cells into cardiac myocytes. Circulation 107, 1912-1916. doi: 10.1161/01.CIR.0000064899.53876.A3
    • (2003) Circulation , vol.107 , pp. 1912-1916
    • Takahashi, T.1    Lord, B.2    Schulze, P.3    Fryer, R.4    Sarang, S.5    Gullans, S.6
  • 30
    • 0028641559 scopus 로고
    • Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor
    • Tontonoz, P., Hu, E., and Spiegelman, B. M. (1994). Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor. Cell 79, 1147-1156. doi: 10.1016/0092-8674(94)90006-X
    • (1994) Cell , vol.79 , pp. 1147-1156
    • Tontonoz, P.1    Hu, E.2    Spiegelman, B.M.3
  • 31
    • 0026031601 scopus 로고
    • CCAAT-enhancer binding protein: a component of a differentiation switch
    • Umek, R. M., Friedman, A. D., and McKnight, S. L. (1991). CCAAT-enhancer binding protein: a component of a differentiation switch. Science 251, 288-292. doi: 10.1126/science.1987644
    • (1991) Science , vol.251 , pp. 288-292
    • Umek, R.M.1    Friedman, A.D.2    McKnight, S.L.3
  • 32
    • 67349152678 scopus 로고    scopus 로고
    • Ascorbic acid enhances adipogenesis of bone marrow-derived mesenchymal stromal cells
    • Weiser, B., Sommer, F., Neubauer, M., Seitz, A., Tessmar, J., Goepferich, A., et al. (2009). Ascorbic acid enhances adipogenesis of bone marrow-derived mesenchymal stromal cells. Cells Tissues Organs 189, 373-381. doi: 10.1159/000154270
    • (2009) Cells Tissues Organs , vol.189 , pp. 373-381
    • Weiser, B.1    Sommer, F.2    Neubauer, M.3    Seitz, A.4    Tessmar, J.5    Goepferich, A.6
  • 33
    • 37549066367 scopus 로고    scopus 로고
    • Ascorbic Acid Transported by Sodium-Dependent Vitamin C Transporter 2 Stimulates Steroidogenesis in Human Choriocarcinoma Cells
    • Wu, X., Iguchi, T., Itoh, N., Okamoto, K., Takagi, T., Tanaka, K., et al. (2008). Ascorbic Acid Transported by Sodium-Dependent Vitamin C Transporter 2 Stimulates Steroidogenesis in Human Choriocarcinoma Cells. Endocrinology 149, 73. doi: 10.1210/en.2007-0262
    • (2008) Endocrinology , vol.149 , pp. 73
    • Wu, X.1    Iguchi, T.2    Itoh, N.3    Okamoto, K.4    Takagi, T.5    Tanaka, K.6
  • 34
    • 0028878375 scopus 로고
    • Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins
    • Yeh, W. C., Cao, Z., Classon, M., and McKnight, S. L. (1995). Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins. Genes Dev. 9, 168-181. doi: 10.1101/gad.9.2.168
    • (1995) Genes Dev. , vol.9 , pp. 168-181
    • Yeh, W.C.1    Cao, Z.2    Classon, M.3    McKnight, S.L.4
  • 35
    • 84866083087 scopus 로고    scopus 로고
    • Different roles of GNAS and cAMP signaling during early and late stages of osteogenic diffrentiation
    • Zhang, S., Kaplan, F. S., and Shore, E. M. (2012). Different roles of GNAS and cAMP signaling during early and late stages of osteogenic diffrentiation. Horm. Metab. Res. 44, 724-731. doi: 10.1055/s-0032-1321845
    • (2012) Horm. Metab. Res. , vol.44 , pp. 724-731
    • Zhang, S.1    Kaplan, F.S.2    Shore, E.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.