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Volumn 171, Issue 3, 2016, Pages 414-426

A pilot integrative genomics study of GABA and glutamate neurotransmitter systems in suicide, suicidal behavior, and major depressive disorder

Author keywords

GABA; Gene expression; Glutamate; Major depressive disorder; Suicidal behavior

Indexed keywords

4 AMINOBUTYRIC ACID; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; GLUTAMIC ACID;

EID: 84975763818     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.32423     Document Type: Article
Times cited : (55)

References (68)
  • 4
    • 84896494376 scopus 로고    scopus 로고
    • Comorbidity between major depression and alcohol use disorder from adolescence to adulthood
    • Briere FN, Rohde P, Seeley JR, Klein D, Lewinsohn PM. 2014. Comorbidity between major depression and alcohol use disorder from adolescence to adulthood. Compr Psychiatry 55:526-533.
    • (2014) Compr Psychiatry , vol.55 , pp. 526-533
    • Briere, F.N.1    Rohde, P.2    Seeley, J.R.3    Klein, D.4    Lewinsohn, P.M.5
  • 7
    • 84887327024 scopus 로고    scopus 로고
    • Investigation of possible epistatic interactions between GRIA2 and GRIA4 variants on clinical outcomes in patients with major depressive disorder
    • Chiesa A, Lia L, Lia C, Lee SJ, Han C, Patkar AA, Pae CU, Serretti A. 2013. Investigation of possible epistatic interactions between GRIA2 and GRIA4 variants on clinical outcomes in patients with major depressive disorder. J Int Med Res 41:809-815.
    • (2013) J Int Med Res , vol.41 , pp. 809-815
    • Chiesa, A.1    Lia, L.2    Lia, C.3    Lee, S.J.4    Han, C.5    Patkar, A.A.6    Pae, C.U.7    Serretti, A.8
  • 10
    • 84901291065 scopus 로고    scopus 로고
    • Expression of GABAA alpha2-, beta1- and epsilon-receptors are altered significantly in the lateral cerebellum of subjects with schizophrenia, major depression, and bipolar disorder
    • Fatemi SH, Folsom TD, Rooney RJ, Thuras PD. 2013. Expression of GABAA alpha2-, beta1- and epsilon-receptors are altered significantly in the lateral cerebellum of subjects with schizophrenia, major depression, and bipolar disorder. Transl Psychiatry 3:e303.
    • (2013) Transl Psychiatry , vol.3 , pp. e303
    • Fatemi, S.H.1    Folsom, T.D.2    Rooney, R.J.3    Thuras, P.D.4
  • 12
    • 77953960630 scopus 로고    scopus 로고
    • Gene expression profiling of suicide completers
    • Fiori LM, Turecki G. 2010. Gene expression profiling of suicide completers. Eur Psychiatry 25:287-290.
    • (2010) Eur Psychiatry , vol.25 , pp. 287-290
    • Fiori, L.M.1    Turecki, G.2
  • 13
    • 0021330769 scopus 로고
    • Glutamate: A neurotransmitter in mammalian brain
    • Fonnum F. 1984. Glutamate: A neurotransmitter in mammalian brain. J Neurochem 42:1-11.
    • (1984) J Neurochem , vol.42 , pp. 1-11
    • Fonnum, F.1
  • 15
    • 77950473496 scopus 로고    scopus 로고
    • The prevalence and impact of depression
    • Gelenberg AJ. 2010. The prevalence and impact of depression. J Clin Psychiatry 71:e06.
    • (2010) J Clin Psychiatry , vol.71 , pp. e06
    • Gelenberg, A.J.1
  • 17
    • 84864852608 scopus 로고    scopus 로고
    • The epidemiology of depression and the evolution of treatment
    • Hirschfeld RM. 2012. The epidemiology of depression and the evolution of treatment. J Clin Psychiatry 73(Suppl 1):5-9.
    • (2012) J Clin Psychiatry , vol.73 , pp. 5-9
    • Hirschfeld, R.M.1
  • 18
    • 0032973456 scopus 로고    scopus 로고
    • Relationship of psychopathology to the human serotonin1B genotype and receptor binding kinetics in postmortem brain tissue
    • Huang YY, Grailhe R, Arango V, Hen R, Mann JJ. 1999. Relationship of psychopathology to the human serotonin1B genotype and receptor binding kinetics in postmortem brain tissue. Neuropsychopharmacology 21:238-246.
    • (1999) Neuropsychopharmacology , vol.21 , pp. 238-246
    • Huang, Y.Y.1    Grailhe, R.2    Arango, V.3    Hen, R.4    Mann, J.J.5
  • 20
    • 0029965048 scopus 로고    scopus 로고
    • Validity of DSM-III-R diagnosis by psychological autopsy: A comparison with clinician ante-mortem diagnosis
    • Kelly TM, Mann JJ. 1996. Validity of DSM-III-R diagnosis by psychological autopsy: A comparison with clinician ante-mortem diagnosis. Acta Psychiatr Scand 94:337-343.
    • (1996) Acta Psychiatr Scand , vol.94 , pp. 337-343
    • Kelly, T.M.1    Mann, J.J.2
  • 22
    • 38349169837 scopus 로고    scopus 로고
    • Suicide candidate genes associated with bipolar disorder and schizophrenia: An exploratory gene expression profiling analysis of post-mortem prefrontal cortex
    • Kim S, Choi KH, Baykiz AF, Gershenfeld HK. 2007. Suicide candidate genes associated with bipolar disorder and schizophrenia: An exploratory gene expression profiling analysis of post-mortem prefrontal cortex. BMC Genomics 8:413.
    • (2007) BMC Genomics , vol.8 , pp. 413
    • Kim, S.1    Choi, K.H.2    Baykiz, A.F.3    Gershenfeld, H.K.4
  • 23
    • 58549120972 scopus 로고    scopus 로고
    • Altered expression of genes involved in ATP biosynthesis and GABAergic neurotransmission in the ventral prefrontal cortex of suicides with and without major depression
    • Klempan TA, Sequeira A, Canetti L, Lalovic A, Ernst C, Ffrench-Mullen J, Turecki G. 2009. Altered expression of genes involved in ATP biosynthesis and GABAergic neurotransmission in the ventral prefrontal cortex of suicides with and without major depression. Mol Psychiatry 14:175-189.
    • (2009) Mol Psychiatry , vol.14 , pp. 175-189
    • Klempan, T.A.1    Sequeira, A.2    Canetti, L.3    Lalovic, A.4    Ernst, C.5    Ffrench-Mullen, J.6    Turecki, G.7
  • 27
    • 84890245268 scopus 로고    scopus 로고
    • Gene environment interaction studies in depression and suicidal behavior: An update
    • Mandelli L, Serretti A. 2013. Gene environment interaction studies in depression and suicidal behavior: An update. Neurosci Biobehav Rev 37:2375-2397.
    • (2013) Neurosci Biobehav Rev , vol.37 , pp. 2375-2397
    • Mandelli, L.1    Serretti, A.2
  • 30
    • 1242314197 scopus 로고    scopus 로고
    • Dysregulation in the suicide brain: mRNA expression of corticotropin-releasing hormone receptors and GABA(A) receptor subunits in frontal cortical brain region
    • Merali Z, Du L, Hrdina P, Palkovits M, Faludi G, Poulter MO, Anisman H. 2004. Dysregulation in the suicide brain: mRNA expression of corticotropin-releasing hormone receptors and GABA(A) receptor subunits in frontal cortical brain region. J Neurosci 24:1478-1485.
    • (2004) J Neurosci , vol.24 , pp. 1478-1485
    • Merali, Z.1    Du, L.2    Hrdina, P.3    Palkovits, M.4    Faludi, G.5    Poulter, M.O.6    Anisman, H.7
  • 32
    • 84958906160 scopus 로고    scopus 로고
    • A pilot in vivo proton magnetic resonance spectroscopy study of amino acid neurotransmitter response to ketamine treatment of major depressive disorder
    • [Epub ahead of print].
    • Milak MS, Proper CJ, Mulhern ST, Parter AL, Kegeles LS, et al. 2015. A pilot in vivo proton magnetic resonance spectroscopy study of amino acid neurotransmitter response to ketamine treatment of major depressive disorder. Mol. Psychiatry doi: 10.1038/mp.2015.83 [Epub ahead of print].
    • (2015) Mol. Psychiatry
    • Milak, M.S.1    Proper, C.J.2    Mulhern, S.T.3    Parter, A.L.4    Kegeles, L.S.5
  • 33
    • 80054090004 scopus 로고    scopus 로고
    • The GABA system in anxiety and depression and its therapeutic potential
    • Mohler H. 2012. The GABA system in anxiety and depression and its therapeutic potential. Neuropharmacology 62:42-53.
    • (2012) Neuropharmacology , vol.62 , pp. 42-53
    • Mohler, H.1
  • 36
    • 84978319710 scopus 로고    scopus 로고
    • NCIPC. 2013. http://www.cdc.gov/violenceprevention/pdf/suicide-datasheet-a.pdf
    • (2013)
  • 37
    • 77951439152 scopus 로고    scopus 로고
    • Trait-associated SNPs are more likely to be eQTLs: Annotation to enhance discovery from GWAS
    • Nicolae DL, Gamazon E, Zhang W, Duan S, Dolan ME, Cox NJ. 2010. Trait-associated SNPs are more likely to be eQTLs: Annotation to enhance discovery from GWAS. PLoS Genet 6:e1000888.
    • (2010) PLoS Genet , vol.6 , pp. e1000888
    • Nicolae, D.L.1    Gamazon, E.2    Zhang, W.3    Duan, S.4    Dolan, M.E.5    Cox, N.J.6
  • 38
    • 75849145292 scopus 로고    scopus 로고
    • Expansion of the eukaryotic proteome by alternative splicing
    • Nilsen TW, Graveley BR. 2010. Expansion of the eukaryotic proteome by alternative splicing. Nature 463:457-463.
    • (2010) Nature , vol.463 , pp. 457-463
    • Nilsen, T.W.1    Graveley, B.R.2
  • 39
    • 84903274647 scopus 로고    scopus 로고
    • An association between the reduced levels of SLC1A2 and GAD1 in the dorsolateral prefrontal cortex in major depressive disorder: Possible involvement of an attenuated RAF/MEK/ERK signaling pathway
    • Oh DH, Oh D, Son H, Webster MJ, Weickert CS, Kim SH. 2014. An association between the reduced levels of SLC1A2 and GAD1 in the dorsolateral prefrontal cortex in major depressive disorder: Possible involvement of an attenuated RAF/MEK/ERK signaling pathway. J Neural Transm 121:783-792.
    • (2014) J Neural Transm , vol.121 , pp. 783-792
    • Oh, D.H.1    Oh, D.2    Son, H.3    Webster, M.J.4    Weickert, C.S.5    Kim, S.H.6
  • 41
    • 84864825091 scopus 로고    scopus 로고
    • Glutamatergic approaches in major depressive disorder: Focus on ketamine, memantine, and riluzole
    • Owen RT. 2012. Glutamatergic approaches in major depressive disorder: Focus on ketamine, memantine, and riluzole. Drugs Today (Barc) 48:469-478.
    • (2012) Drugs Today (Barc) , vol.48 , pp. 469-478
    • Owen, R.T.1
  • 43
    • 0029164246 scopus 로고
    • GABA and mood disorders: A brief review and hypothesis
    • Petty F. 1995. GABA and mood disorders: A brief review and hypothesis. J Affect Disord 34:275-281.
    • (1995) J Affect Disord , vol.34 , pp. 275-281
    • Petty, F.1
  • 44
    • 34249333702 scopus 로고    scopus 로고
    • Columbia Classification Algorithm of Suicide Assessment (C-CASA): Classification of suicidal events in the FDA's pediatric suicidal risk analysis of antidepressants
    • Posner K, Oquendo MA, Gould M, Stanley B, Davies M. 2007. Columbia Classification Algorithm of Suicide Assessment (C-CASA): Classification of suicidal events in the FDA's pediatric suicidal risk analysis of antidepressants. Am J Psychiatry 164:1035-1043.
    • (2007) Am J Psychiatry , vol.164 , pp. 1035-1043
    • Posner, K.1    Oquendo, M.A.2    Gould, M.3    Stanley, B.4    Davies, M.5
  • 45
    • 84873675611 scopus 로고    scopus 로고
    • Influence of genetic polymorphisms in the glutamatergic and GABAergic systems and their interactions with environmental stressors on antidepressant response
    • Pu M, Zhang Z, Xu Z, Shi Y, Geng L, Yuan Y, Zhang X, Reynolds GP. 2013. Influence of genetic polymorphisms in the glutamatergic and GABAergic systems and their interactions with environmental stressors on antidepressant response. Pharmacogenomics 14:277-288.
    • (2013) Pharmacogenomics , vol.14 , pp. 277-288
    • Pu, M.1    Zhang, Z.2    Xu, Z.3    Shi, Y.4    Geng, L.5    Yuan, Y.6    Zhang, X.7    Reynolds, G.P.8
  • 47
    • 34247628030 scopus 로고    scopus 로고
    • GABAergic contributions to the pathophysiology of depression and the mechanism of antidepressant action
    • Sanacora G, Saricicek A. 2007. GABAergic contributions to the pathophysiology of depression and the mechanism of antidepressant action. CNS Neurol Disord Drug Targets 6:127-140.
    • (2007) CNS Neurol Disord Drug Targets , vol.6 , pp. 127-140
    • Sanacora, G.1    Saricicek, A.2
  • 48
    • 0033800486 scopus 로고    scopus 로고
    • Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders
    • Sapolsky RM. 2000. Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders. Arch Gen Psychiatry 57:925-935.
    • (2000) Arch Gen Psychiatry , vol.57 , pp. 925-935
    • Sapolsky, R.M.1
  • 52
    • 84896317561 scopus 로고    scopus 로고
    • Alcohol dependence and suicide-related ideation/behaviors in an Israeli household sample, with and without major depression
    • Shoval G, Shmulewitz D, Wall MM, Aharonovich E, Spivak B, Weizman A, Hasin D. 2014. Alcohol dependence and suicide-related ideation/behaviors in an Israeli household sample, with and without major depression. Alcohol Clin Exp Res 38:820-825.
    • (2014) Alcohol Clin Exp Res , vol.38 , pp. 820-825
    • Shoval, G.1    Shmulewitz, D.2    Wall, M.M.3    Aharonovich, E.4    Spivak, B.5    Weizman, A.6    Hasin, D.7
  • 54
    • 84883197987 scopus 로고    scopus 로고
    • Glutamatergic GRIN2B and polyaminergic ODC1 genes in suicide attempts: Associations and gene-environment interactions with childhood/adolescent physical assault
    • Sokolowski M, Ben-efraim YJ, Wasserman J, Wasserman D. 2013. Glutamatergic GRIN2B and polyaminergic ODC1 genes in suicide attempts: Associations and gene-environment interactions with childhood/adolescent physical assault. Mol Psychiatry 18:985-992.
    • (2013) Mol Psychiatry , vol.18 , pp. 985-992
    • Sokolowski, M.1    Ben-efraim, Y.J.2    Wasserman, J.3    Wasserman, D.4
  • 55
    • 0026769858 scopus 로고
    • The structured clinical interview for DSM-III-R (SCID). I: History, rationale, and description
    • Spitzer RL, Williams JB, Gibbon M, First MB. 1992. The structured clinical interview for DSM-III-R (SCID). I: History, rationale, and description. Arch Gen Psychiatry 49:624-629.
    • (1992) Arch Gen Psychiatry , vol.49 , pp. 624-629
    • Spitzer, R.L.1    Williams, J.B.2    Gibbon, M.3    First, M.B.4
  • 56
    • 0036218088 scopus 로고    scopus 로고
    • Antidepressant mechanisms: Functional and molecular correlates of excitatory amino acid neurotransmission
    • Stewart CA, Reid IC. 2002. Antidepressant mechanisms: Functional and molecular correlates of excitatory amino acid neurotransmission. Mol Psychiatry 7(Suppl 1):S15-S22.
    • (2002) Mol Psychiatry , vol.7 , pp. S15-S22
    • Stewart, C.A.1    Reid, I.C.2
  • 57
    • 84859527621 scopus 로고    scopus 로고
    • Transcript-specific associations of SLC12A5 (KCC2) in human prefrontal cortex with development, schizophrenia, and affective disorders
    • Tao R, Li C, Newburn EN, Ye T, Lipska BK, Herman MM, Weinberger DR, Kleinman JE, Hyde TM. 2012. Transcript-specific associations of SLC12A5 (KCC2) in human prefrontal cortex with development, schizophrenia, and affective disorders. J Neurosci 32:5216-5222.
    • (2012) J Neurosci , vol.32 , pp. 5216-5222
    • Tao, R.1    Li, C.2    Newburn, E.N.3    Ye, T.4    Lipska, B.K.5    Herman, M.M.6    Weinberger, D.R.7    Kleinman, J.E.8    Hyde, T.M.9
  • 59
    • 80053572217 scopus 로고    scopus 로고
    • Quality control parameters on a large dataset of regionally dissected human control brains for whole genome expression studies
    • Trabzuni D, Ryten M, Walker R, Smith C, Imran S, Ramasamy A, Weale ME, Hardy J. 2011. Quality control parameters on a large dataset of regionally dissected human control brains for whole genome expression studies. J Neurochem 119:275-282.
    • (2011) J Neurochem , vol.119 , pp. 275-282
    • Trabzuni, D.1    Ryten, M.2    Walker, R.3    Smith, C.4    Imran, S.5    Ramasamy, A.6    Weale, M.E.7    Hardy, J.8
  • 61
    • 84868599247 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor signaling and subgenual anterior cingulate cortex dysfunction in major depressive disorder
    • Tripp A, Oh H, Guilloux JP, Martinowich K, Lewis DA, Sibille E. 2012. Brain-derived neurotrophic factor signaling and subgenual anterior cingulate cortex dysfunction in major depressive disorder. Am J Psychiatry 169:1194-1202.
    • (2012) Am J Psychiatry , vol.169 , pp. 1194-1202
    • Tripp, A.1    Oh, H.2    Guilloux, J.P.3    Martinowich, K.4    Lewis, D.A.5    Sibille, E.6
  • 63
    • 78649903947 scopus 로고    scopus 로고
    • Suicidal brains: A review of functional and structural brain studies in association with suicidal behaviour
    • van Heeringen C, Bijttebier S, Godfrin K. 2011. Suicidal brains: A review of functional and structural brain studies in association with suicidal behaviour. Neurosci Biobehav Rev 35:688-698.
    • (2011) Neurosci Biobehav Rev , vol.35 , pp. 688-698
    • van Heeringen, C.1    Bijttebier, S.2    Godfrin, K.3
  • 65
    • 84978325101 scopus 로고    scopus 로고
    • World Health Organization. 2014. http://www.who.int/mediacentre/factsheets/fs398/en
    • (2014)


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