Suicidal brains: A review of functional and structural brain studies in association with suicidal behaviour

Neuroscience and Biobehavioral Reviews

Volumn 35, Issue 3, 2011, Pages 688-698

  van Heeringen, C ^a   Bijttebier, S ^a   Godfrin, K ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Decision making; DTI; FMRI; MRI; Neurobiology; Neuroimaging; PET; Prefrontal cortex; SPECT; Suicidal brain; Suicide

Indexed keywords

BRAIN FUNCTION; BRAIN SIZE; COMPUTER ASSISTED TOMOGRAPHY; DECISION MAKING; DIFFUSION TENSOR IMAGING; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GRAY MATTER; HUMAN; MENTAL DISEASE; NEUROLOGIC DISEASE; ORBITAL CORTEX; POSITRON EMISSION TOMOGRAPHY; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROBLEM SOLVING; REVIEW; REWARD; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SUICIDAL BEHAVIOR; WHITE MATTER;

ASSOCIATION; BRAIN; DATABASES, FACTUAL; DECISION MAKING; DIAGNOSTIC IMAGING; HUMANS; RISK FACTORS; SUICIDE;

EID: 78649903947     PISSN: 01497634     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neubiorev.2010.08.007     Document Type: Review

References (37)

1. Aguilar E.J., Garcia-Marti G., Marti-Bonmati L., Lull J.J., Moratal D., Escarti M.J., Robles M., Gonzales M.I., Guillamon J.C., Sanjuan J. Left orbitofrontal and superior temporal gyrus structural changes associated to suicidal behavior in patients with schizophrenia. Prog. Neuropsychopharmacol. Biol. Psychiatry 2008, 32:1673-1676.
2. Ahearn E.P., Jamison K.R., Steffens D.C., Cassidy F., Provenzale J.M., Lehman A., Weisler R.H., Carroll B.J., Krishnan K.R.R. MRI correlates of suicide attempt history in unipolar depression. Biol. Psychiatry 2001, 50:266-270.
3. Amen D.G., Prunella J.R., Fallon J.H., Amen B., Hanks C. A comparative analysis of completed suicide using high resolution brain SPECT imaging. J. Neuropsychiatry Clin. Neurosci. 2009, 21:430-439.
4. Audenaert K., Goethals I., Van Laere K., Lahorte P., Brans B., Versijpt J., Vervaet M., Beelaert L., van Heeringen K., Dierckx R. SPECT neuropsychological activation procedure with the Verbal Fluency Test in attempted suicide patients. Nucl. Med. Commun. 2002, 23:907-916.
5. 2a receptor binding index in deliberate self-harm patients. Eur. J. Nucl. Med. 2001, 28:175-182.
6. Cannon D.M., Ichise M., Rollis D., Klaver J.M., Gandhi S.K., Charney D.S., Manji H.K., Drevets W.C. Elevated serotonin transporter binding in major depressive disorder assessed using positron emission tomography and [C-11]DASB; comparison with bipolar disorder. Biol. Psychiatry 2007, 62:870-877.
7. Ehrlich S., Noam G.G., Lyoo I.K., Kwon B.J., Clark M.A., Renshaw P.F. White matter hyperintensities and their associations with suicidality in psychiatrically hospitalized children and adolescents. J. Am. Acad. Child. Adolesc. Psychiatry 2004, 43:770-776.
8. Ehrlich S., Breeze J.L., Hesdorffer D.C., Noam G.G., Hong X., Alban R.L., Davis S.E., Renshaw P.F. White matter hyperintensities and their association with suicidality in depressed young adults. J. Affect. Disord. 2005, 86:281-287.
9. Hawton K., van Heeringen K. Suicide. Lancet 2009, 373:1372-1381.
10. Horn N.R., Dolan M., Elliott R., Deakin J.F.W., Woodruff P.W.R. Response inhibition and impulsivity: an fMRI study. Neuropsychologia 2003, 41:1959-1966.
11. Jollant F., Bellivier F., Leboyer M., Astruc B., Torres S., Verdier R., Castelnau D., Malafosse A., Courtet P. Impaired decision making in suicide attempters. Am. J. Psychiatry 2005, 162:304-310.
12. Jollant F., Lawrence N.S., Giampietro V., Brammer M.J., Fullana M.A., Drapier D., Courtet P., Phillips M.L. Orbitofrontal cortex response to angry faces in men with histories of suicide attempts. Am. J. Psychiatry 2008, 165:740-748.
13. Jollant F., Lawrence N.S., Olie E., O'Daly O., Malafosse A., Courtet P., Phillips M.L. Decreased activation of lateral orbitofrontal cortex during risky choices under uncertainty is associated with disadvantageous decision-making and suicidal behavior. NeuroImage 2010, 51:1275-1281.
14. Jovev M., Garner B., Phillips L., Velakoulis D., Wood S.J., Jackson H.J., Pantelis C., McGorry P.D., Chanen A.M. An MRI study of pituitary volume and parasuicidal behavior in teenagers with first-presentation borderline personality disorder. Psychiatr. Res. Neuroimaging 2008, 162:273-277.
15. Kerkhof A.J.F.M. Attempted suicide: patterns and trends. The International Handbook of Suicide and Attempted Suicide 2000, 49-64. John Wiley & Sons Ltd., Chichester. K. Hawton, K. van Heeringen (Eds.).
16. 11C]Methyl-l-tryptophan trapping in the orbital and ventral medial prefrontal cortex of suicide attempters. Eur. Neuropsychopharmacol. 2006, 16:220-223.
17. Lindström M.B., Ryding E., Bosson P., Ahnlide J.A., Rosén I., Träskman-Bendz L. Impulsivity related to brain serotonin transporter binding capacity in suicide attempters. Eur. Neuropsychopharmacol. 2004, 14:295-300.
18. Lo C.P., Chen S.Y., Chou M.C., Wang C.Y., Lee K.W., Hsueh C.J., Chen C.Y., Huang K.L., Huang G.S. Diffusion-tensor MR imaging for evaluation of the efficacy of hyperbaric oxygen therapy in patients with delayed neuropsychiatric syndrome caused by carbon monoxide inhalation. Eur. J. Neurol. 2007, 14:777-782.
19. MacLeod A.K., Rose G.S., Williams J.M.G. Components of hopelessness about the future in parasuicide. Cognit. Ther. Res. 1993, 17:441-455.
20. Mann J.J. What does brain imaging tell us about the predisposition to suicidal behavior. Crisis 2005, 26:101-103.
21. Matsuo K., Nielsen N., Nicoletti M.A., Hatch J.P., Monkul E.S., Watanabe Y., Zunta-Soares G.B., Nery F.G., Soares J.C. Anterior genu corpus callosum and impulsivity in suicidal patients with bipolar disorder. Neurosci. Lett. 2010, 469:75-80.
22. 2 receptors during depression and self-harm. Am. J. Psychiatry 2003, 160:90-99.
23. Monkul E.S., Hatch J.P., Nicoletti M.A., Spence S., Brambilla P., Lacerda A.L.T., Sassi R.B., Mallinger A.G., Keshavan M.S., Soares J.C. Fronto-limbic brain structures in suicidal and non-suicidal female patients with major depressive disorder. Mol. Psychiatry 2007, 12:360-366.
24. Oquendo M.A., Placidi G.P.A., Malone K.M., Campbell C., Keilp J., Brodsky B., Kegeles L.S., Cooper T.B., Parsey R.V., Van Heertum R.L., Mann J.J. Positron emission tomography of regional brain metabolic responses to a serotonergic challenge and lethality of suicide attempts in major depression. Arch. Gen. Psychiatry 2003, 60:14-22.
25. Pompili M., Ehrlich S., De Pisa E., Mann J.J., Innamorati M., Cittadini A., Montagna B., Iliceto P., Romano A., Amore M., Tatarelli R., Girardi P. White matter hyperintensities and their associations with suicidality in patients with major affective disorders. Eur. Arch. Psychiatry Clin. Neurosci. 2007, 257:494-499.
26. Pompili M., Innamorati M., Mann J.J., Oquendo M.A., Lester D., Del Casale A., Serafini G., Rigucci S., Romano A., Tamburello A., Manfredi G., De Pisa E., Ehrlich S., Giupponi G., Amore M., Tatarelli R., Girardi P. Periventricular white matter hyperintensities as predictors of suicide attempts in bipolar disorders and unipolar depression. Prog. Neuropsychopharmacol. Biol. Psychiatry 2008, 32:1501-1507.
27. Rüsch N., Spoletini I., Wilke M., Martinotti G., Bria P., Trequattrini A., Bonaviri G., Caltagirone C., Spalletta G. Inferior frontal white matter volume and suicidality in schizophrenia. Psychiatr. Res. Neuroimaging 2008, 164:206-214.
28. Ryding E., Ahnlide J.A., Lindström M., Rosén I., Träskman-Bendz L. Regional brain serotonin and dopamine transporter binding capacity in suicide attempters relate to impulsiveness and mental energy. Psychiatr. Res. Neuroimaging 2006, 148:195-203.
29. Schweighofer N., Tanaka S.C., Doya K. Serotonin and the evaluation of future rewards-theory, experiments, and possible neural mechanisms. Ann. N. Y. Acad. Sci. 2007, 1104:289-300.
30. Soares J.C., Mann J.J. The anatomy of mood disorders-review of the structural neuroimaging studies. Biol. Psychiatry 1997, 41:86-106.
31. Soloff P.H., Meltzer C.C., Becker C., Greer P.J., Kelly T.M., Constantine D. Impulsivity and prefrontal hypometabolism in borderline personality disorder. Psychiatr. Res. Neuroimaging 2003, 123:153-163.
32. 2A receptor binding is increased in borderline personality disorder. Biol. Psychiatry 2007, 62:580-587.
33. Tanaka S.C., Doya K., Okada G., Ueda K., Okamoto Y., Yamawaki S. Different cortico-basal ganglia loops specialize in reward prediction at different time scales. Adv. Neural Inf. Process. Syst. 2004, 16:701-708.
34. Tanaka S.C., Doya K., Okada G., Ueda K., Okamoto Y., Yamawaki S. Prediction of immediate and future rewards differentially recruits cortico-basal ganglia loops. Nat. Neurosci. 2004, 7:887-893.
35. van Heeringen C., Audenaert K., Van Laere K., Dumont F., Slegers G., Mertens J., Dierckx R.A. Prefrontal 5-HT2a receptor binding index, hopelessness and personality characteristics in attempted suicide. J. Affect. Disord. 2003, 74:149-158.
36. van Heeringen K., Van den Abbeele D., Vervaet M., Soenen L., Audenaert K. The functional neuroanatomy of mental pain in depression. Psychiatr. Res. Neuroimaging 2010, 181:141-144.
37. WHO World Report on Violence and Health 2002, World Health Organization, Geneva. 1st ed.