Activating AMP-activated protein kinase by an α1 selective activator compound 13 attenuates dexamethasone-induced osteoblast cell death

Biochemical and Biophysical Research Communications

Volumn 471, Issue 4, 2016, Pages 545-552

  Guo, Shiguang ^a   Mao, Li ^a   Ji, Feng ^a   Wang, Shouguo ^a   Xie, Yue ^a   Fei, Haodong ^a   Wang, Xiao Dong ^b  

^a NANJING MEDICAL UNIVERSITY   (China)

^b CHILDREN S HOSPITAL OF SOOCHOW UNIVERSITY   (China)

Author keywords

AMP activated protein kinase (AMPK); Compound 13; Glucocorticoid; NADPH; Osteoblasts; Oxidative stresses

Indexed keywords

6,7 DIHYDRO 4 HYDROXY 3 (2' HYDROXY 1,1' BIPHENYL 4 YL) 6 OXOTHIENO[2,3 B]PYRIDINE 5 CARBONITRILE; DEXAMETHASONE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE ACTIVATOR; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SHORT HAIRPIN RNA; GLUCOCORTICOID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PYRONE DERIVATIVE; SMALL INTERFERING RNA; THIOPHENE DERIVATIVE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; DRUG INHIBITION; ENZYME ACTIVATION; NONHUMAN; OSTEOBLAST; OXIDATIVE STRESS; PRIMARY CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; DRUG EFFECTS; ENZYMOLOGY; GENETICS; METABOLISM; MOUSE; MUTATION; PRIMARY CELL CULTURE;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; APOPTOSIS; CELL LINE; DEXAMETHASONE; ENZYME ACTIVATION; GLUCOCORTICOIDS; MICE; MUTATION; NADP; OSTEOBLASTS; PRIMARY CELL CULTURE; PYRONES; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; THIOPHENES;

EID: 84975744689     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2016.02.036     Document Type: Article

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