Postexercise high-fat feeding suppresses p70S6K1 activity in human skeletal muscle

Medicine and Science in Sports and Exercise

Volumn 48, Issue 11, 2016, Pages 2108-2117

  Hammond, Kelly M ^a   Impey, Samuel G ^a   Currell, Kevin ^b   Mitchell, Nigel ^b   Shepherd, Sam O ^a   Jeromson, Stewart ^c   Hawley, John A ^a,d   Close, Graeme L ^a   Hamilton, Lee D ^c   Sharples, Adam P ^a   Morton, James P ^a  

^a LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

^b LOUGHBOROUGH UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF STIRLING   (United Kingdom)

^d AUSTRALIAN CATHOLIC UNIVERSITY   (Australia)

Author keywords

AMPK 2; GLYCOGEN; MITOCHONDRIAL BIOGENESIS; p53; PGC 1

Indexed keywords

CARBOHYDRATE DIET; FAT INTAKE; GLYCOGEN; MUSCLE PROTEIN; S6 KINASE;

ADMINISTRATION AND DOSAGE; BIOSYNTHESIS; CARBOHYDRATE DIET; CONTROLLED STUDY; CROSSOVER PROCEDURE; ENZYMOLOGY; EXERCISE; FAT INTAKE; GENE EXPRESSION; GENETICS; HUMAN; LIPID METABOLISM; MALE; METABOLISM; ORGANELLE BIOGENESIS; PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; YOUNG ADULT;

CROSS-OVER STUDIES; DIETARY CARBOHYDRATES; DIETARY FATS; EXERCISE; GENE EXPRESSION; GLYCOGEN; HUMANS; LIPID METABOLISM; MALE; MUSCLE PROTEINS; MUSCLE, SKELETAL; ORGANELLE BIOGENESIS; RIBOSOMAL PROTEIN S6 KINASES; SIGNAL TRANSDUCTION; YOUNG ADULT;

EID: 84975453733     PISSN: 01959131     EISSN: 15300315     Source Type: Journal    
DOI: 10.1249/MSS.0000000000001009     Document Type: Article

References (40)

1. Akerstrom TCA, Birk JB, Klein DK, et al. Oral glucose ingestion attenuates exercise-induced activation of 5-AMP-Activated protein kinase in human skeletal muscle. Biochem Biophys Res Commun. 2006; 342(3): 949-55
2. American College of Sports Medicine, Rodriguez NR, Di Marco NM, Langley S. American College of Sports Medicine Position Stand: nutrition and athletic performance. Med Sci Sports Exerc. 2009; 41(3): 709-31
3. Apro W, Moberg M, Hamilton DL, et al. Resistance exerciseinduced S6K1 kinase activity is not inhibited in human skeletal muscle despite prior activation of AMPK by high-intensity interval cycling. Am J Physiol Endocrinol Metab. 2015; 308(6): 470-81
4. Arkinstall MJ, Tunstall RJ, Cameron-Smith D, Hawley JA. Regulation of metabolic genes in human skeletal muscle by short-Term exercise and diet manipulation. Am J Physiol Endocrinol Metab. 2004; 287: E25-31
5. Bartlett JD, Hawley JA, Morton JP. Carbohydrate availability and exercise training adaptation: too much of a good thing? Eur J Sport Sci. 2015; 15(1): 3-12
6. Bartlett JD, Joo CH, Jeong TS, et al. Matched work high-intensity interval and continuous running induce similar increases in PGC-1 mRNA, AMPK, p38, and p53 phosphorylation in human skeletal muscle. J Appl Physiol. 2012; 112(7): 1135-43
7. Bartlett JD, Joo CH, Louhelainen J, et al. reduced carbohydrate availability enhances exercise-induced phosphorylation of p53 in human skeletal muscle: implications for mitochondrial biogenesis. Am J Physiol Regul Integr Comp Physiol. 2013; (304): R450-8
8. Benziane B, Burton TJ, Scanlan B, et al. Divergent cell signalling after short-Term intensified endurance training in human skeletal muscle. Am J Physiol Endocrinol Metab. 2008; 295(6): E1427-38
9. Borg GA. Perceived exertion: a note on Fhistory and methods. Med Sci Sports. 1973; 5: 90-3
10. Burke LM. Re-examining high-fat diets for performance: did we call the Fnail in the coffin too soon? Sports Med. 2015; 45(1): 33-49
11. Cameron-Smith D, Burke LM, Angus DJ, et al. A short-Term, highfat diet up-regulates lipid metabolism and gene expression in human skeletal muscle. Am J Clin Nutr. 2003; 77(2): 313-8
12. Cochran AJ, Little JP, Tarnopolsky MA, Gibala MJ. Carbohydrate feeding during recovery alters the skeletal muscle metabolic response to repeated sessions of high-intensity interval exercise in humans. J Appl Physiol (1985). 2010; 108: 628-36
13. Egan B, Carson BP, Garcia-Roves PM, et al. Exercise intensitydependent regulation of peroxisome proliferator-Activated receptor F coactivator-1 mRNA abundance is associated with different activation of upstream signalling kinases in human skeletal muscle. J Physiol. 2010; 588.10: 1779-90
14. Fudge BW, Westerterp KR, Kiplamai FK, et al. Evidence of negative energy balance using doubly labelled water in elite Kenyan endurance runners prior to competition. Br J Nutr. 2006; 95(1): 59-66
15. Goedecke JH, Christie C, Wilson G, et al. Metabolic adaptations to a high-fat diet in endurance cyclists. Metabolism. 1999; 48(12): 1509-17
16. Hansen AK, Fischer CP, Plomgaard P, Andersen JL, Saltin B, Pedersen BK. Skeletal muscle adaptation: training twice every second day vs. training once daily. J Appl Physiol (1985). 2005; 98(1): 93-9
17. Hulston CJ, Venables MC, Mann CH, et al. Training with low muscle glycogen enhances fat metabolism in well trained cyclists. Med Sci Sports Exerc. 2010; 42(11): 2046-65
18. Impey SG, Hammond KM, Shepherd SO, et al. Fuel for the work required: a practical approach to amalgamating train-low paradigms for endurance athletes. Physiol Rep. 2016; 4: e12803
19. Jensen TE, Leutert R, Rasmussen ST, et al. EMG-normalised kinase activation during exercise is higher in human gastrocnemius compared to soleus muscle. PLoS One. 2012; 7: e31054
20. Jeukendrup AE, Wallis GA. Measurement of substrate oxidation during exercise by means of gas exchange measurements. Int J Sports Med. 2005; (1 Suppl): S28-37
21. Kimball SR, Ravi S, Gordon BS, Dennis MD, Jefferson LS. Amino acid-induced activation of mTORC1 in rat liver is attenuated by short-Term consumption of a high-fat diet. J Nutri. 2015; 145(11): 2496-2502
22. Kristensen DE, Albers PH, Prats C, Baba O, Birk JB. Human muscle fibre-Type specific regulation of AMPK and downstream targets by exercise. J Physiol. 2015; 593(8): 2053-69
23. Lane SC, Camera DM, Lassiter DG, et al. Effects of sleeping with reduced carbohydrate availability on acute training responses. J Appl Physiol (1985). 2015; 119(6): 643-55
24. Marquet LA, Brisswalter J, Louis J, et al. Enhanced endurance performance by periodization of CHO intake: sleep low strategy. Med Sci Sports Exerc. 2016; 48(4): 663-72
25. Mascher H, Andersson H, Nilsson PA, Ekbolm B, Blomstrand E. Changes in signalling pathways regulating protein synthesis in human muscle in the recovery period after endurance exercise. Acta Physiol (Oxf). 2007; 191: 67-75
26. McBride A, Ghilagaber S, Nikolaev A, Hardie DG. The glycogenbinding domain on the AMPK A subunit allows the kinase to act as a glycogen sensor. Cell Metab. 2009; 9: 23-34
27. McGlory C, White A, Treins C, et al. Application of the [F-32P] ATP kinase assay to study anabolic signalling in human skeletal muscle. J Appl Physiol (1985). 2013; 116(5): 504-13
28. Moore DR, Camera DM, Areta JL, Hawley JA. Beyond muscle hypertrophy: why dietary protein is important for endurance athletes. Appl Physiol Nutr Metab. 2014; 39(9): 987-97
29. Morton JP, Croft L, Bartlett JD, et al. Reduced carbohydrate availability does not modulate training-induced heat shock protein adaptations but does up regulate oxidative enzyme activity in human skeletal muscle. J Appl Physiol. 2009; 106: 1513-21
30. Philp A, Hargreaves M, Baar K. More than a store: regulatory roles for glycogen in skeletal muscle adaptation to exercise. Am J Physiol Endocrinol Metab. 2012; 302: E1343-51
31. Philp A, MacKenzie MG, Belew MY, et al. Glycogen content regulates peroxisome proliferator activated receptor-C (PPAR-C) activity in rat skeletal muscle. PLoS One. 2013; 8: e77200
32. Pilegaard H, Osada T, Andersen LT, Helge JW, Saltin B, Neufer PD. Substrate availability and transcriptional regulation of metabolic genes in human skeletal muscle during recovery from exercise. Metabolism. 2005; 54(8): 1048-55
33. Psilander N, Frank P, Flockhart M, Sahlin K. Exercise with low glycogen increases PGC-1 gene expression in human skeletal muscle. Eur J Appl Physiol. 2013; 113: 951-63
34. Schmittgen TD, Livak KJ. Analyzing real-Time PCR data by the comparative C(T) method. Nat Protoc. 2008; 3(6): 1101-8
35. Stellingwerff T, Spriet LL, Watt MJ, et al. Decreased PDH activation and glycogenolysis during exercise following fat adaptation with carbohydrate restoration. Am J Physiol Endocrinol Metab. 2006; 290(2): E380-8
36. Stephens FB, Chee C, Wall BJ, et al. Lipid-induced insulin resistance is associated with an impaired skeletal muscle protein synthetic response to amino acid ingestion in healthy young men. Diabetes. 2015; 64: 1615-20
37. van Loon LJ, Saris WH, Kruijshoop M, Wagenmakers AJ. Maximizing postexercise muscle protein synthesis: carbohydrate supplementation and the application of amino acid or protein hydrolysate mixtures. Am J Clin Nutr. 2000; 72(1): 106-1
38. Yeo WK, Lessard SJ, Chen ZP, et al. Fat adaptation followed by carbohydrate restoration increases AMPK activity in skeletal muscle from trained humans. J Appl Physiol. 2008; 105(5): 1519-26
39. Yeo WK, Paton CD, Garnham AP, Burke LM, Carey AL, Hawley JA. Skeletal muscle adaptation and performance responses to once versus twice every second day endurance training regimens. J Appl Physiol (1985). 2008; 105: 1462-70
40. Zbinden-Foncea H, van Loon LJC, Raymackers J, Francaux M, Deldicque L. Contribution of nonesterified fatty acids to mitogenactivated protein kinase activation in human skeletal muscle during endurance exercise. Int J Sport Nutr Exerc Metab. 2003; 23: 201-9