-
1
-
-
0029089617
-
A molecular pathway determining left-right asymmetry in chick embryogenesis
-
Levin M, Johnson RL, Stern CD, Kuehn M, Tabin C. A molecular pathway determining left-right asymmetry in chick embryogenesis. Cell. 1995;82:803-14.
-
(1995)
Cell
, vol.82
, pp. 803-814
-
-
Levin, M.1
Johnson, R.L.2
Stern, C.D.3
Kuehn, M.4
Tabin, C.5
-
2
-
-
0031238780
-
Left/right patterning signals and the independent regulation of different aspects of situs in the chick embryo
-
Levin M, Pagan S, Roberts DJ, Cooke J, Kuehn MR, Tabin CJ. Left/right patterning signals and the independent regulation of different aspects of situs in the chick embryo. Dev Biol. 1997;189:57-67.
-
(1997)
Dev Biol
, vol.189
, pp. 57-67
-
-
Levin, M.1
Pagan, S.2
Roberts, D.J.3
Cooke, J.4
Kuehn, M.R.5
Tabin, C.J.6
-
3
-
-
79956206459
-
Histone deacetylase activity is necessary for left-right patterning during vertebrate development
-
Carneiro K, Donnet C, Rejtar T, Karger BL, Barisone GA, Diaz E, Kortagere S, Lemire JM, Levin M. Histone deacetylase activity is necessary for left-right patterning during vertebrate development. BMC Dev Biol. 2011;11:29.
-
(2011)
BMC Dev Biol
, vol.11
, pp. 29
-
-
Carneiro, K.1
Donnet, C.2
Rejtar, T.3
Karger, B.L.4
Barisone, G.A.5
Diaz, E.6
Kortagere, S.7
Lemire, J.M.8
Levin, M.9
-
4
-
-
84871546531
-
TGF-beta-superfamily signaling regulates embryonic stem cell heterogeneity: self-renewal as a dynamic and regulated equilibrium
-
Galvin-Burgess KE, Travis ED, Pierson KE, Vivian JL. TGF-beta-superfamily signaling regulates embryonic stem cell heterogeneity: self-renewal as a dynamic and regulated equilibrium. Stem Cells. 2013;31:48-58.
-
(2013)
Stem Cells
, vol.31
, pp. 48-58
-
-
Galvin-Burgess, K.E.1
Travis, E.D.2
Pierson, K.E.3
Vivian, J.L.4
-
5
-
-
16244400050
-
TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells
-
James D, Levine AJ, Besser D, Hemmati-Brivanlou A. TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells. Development. 2005;132:1273-82.
-
(2005)
Development
, vol.132
, pp. 1273-1282
-
-
James, D.1
Levine, A.J.2
Besser, D.3
Hemmati-Brivanlou, A.4
-
6
-
-
84860804090
-
Potential for the embryonic morphogen Nodal as a prognostic and predictive biomarker in breast cancer
-
Strizzi L, Hardy KM, Margaryan NV, Hillman DW, Seftor EA, Chen B, Geiger XJ, Thompson EA, Lingle WL, Andorfer CA, Perez EA, Hendrix MJ. Potential for the embryonic morphogen Nodal as a prognostic and predictive biomarker in breast cancer. Breast Cancer Res. 2012;14:R75.
-
(2012)
Breast Cancer Res
, vol.14
, pp. R75
-
-
Strizzi, L.1
Hardy, K.M.2
Margaryan, N.V.3
Hillman, D.W.4
Seftor, E.A.5
Chen, B.6
Geiger, X.J.7
Thompson, E.A.8
Lingle, W.L.9
Andorfer, C.A.10
Perez, E.A.11
Hendrix, M.J.12
-
7
-
-
79955837342
-
Expression of nodal and nodal receptors in prostate stem cells and prostate cancer cells: autocrine effects on cell proliferation and migration
-
Vo BT, Khan SA. Expression of nodal and nodal receptors in prostate stem cells and prostate cancer cells: autocrine effects on cell proliferation and migration. Prostate. 2011;71:1084-96.
-
(2011)
Prostate
, vol.71
, pp. 1084-1096
-
-
Vo, B.T.1
Khan, S.A.2
-
8
-
-
80052742592
-
Inhibition of Nodal suppresses angiogenesis and growth of human gliomas
-
Hueng DY, Lin GJ, Huang SH, Liu LW, Ju DT, Chen YW, Sytwu HK, Chang C, Huang SM, Yeh YS, Lee HM, Ma HI. Inhibition of Nodal suppresses angiogenesis and growth of human gliomas. J Neurooncol. 2011;104:21-31.
-
(2011)
J Neurooncol
, vol.104
, pp. 21-31
-
-
Hueng, D.Y.1
Lin, G.J.2
Huang, S.H.3
Liu, L.W.4
Ju, D.T.5
Chen, Y.W.6
Sytwu, H.K.7
Chang, C.8
Huang, S.M.9
Yeh, Y.S.10
Lee, H.M.11
Ma, H.I.12
-
9
-
-
77949808547
-
The embryonic morphogen, nodal, is associated with channel-like structures in human malignant melanoma xenografts
-
McAllister JC, Zhan Q, Weishaupt C, Hsu MY, Murphy GF. The embryonic morphogen, nodal, is associated with channel-like structures in human malignant melanoma xenografts. J Cutan Pathol. 2010;37(Suppl 1):19-25.
-
(2010)
J Cutan Pathol
, vol.37
, pp. 19-25
-
-
McAllister, J.C.1
Zhan, Q.2
Weishaupt, C.3
Hsu, M.Y.4
Murphy, G.F.5
-
10
-
-
79957624574
-
Embryonic signaling in melanoma: potential for diagnosis and therapy
-
Strizzi L, Hardy KM, Kirsammer GT, Gerami P, Hendrix MJ. Embryonic signaling in melanoma: potential for diagnosis and therapy. Lab Invest. 2011;91:819-24.
-
(2011)
Lab Invest
, vol.91
, pp. 819-824
-
-
Strizzi, L.1
Hardy, K.M.2
Kirsammer, G.T.3
Gerami, P.4
Hendrix, M.J.5
-
11
-
-
33746846469
-
Embryonic and tumorigenic pathways converge via Nodal signaling: role in melanoma aggressiveness
-
Topczewska JM, Postovit LM, Margaryan NV, Sam A, Hess AR, Wheaton WW, Nickoloff BJ, Topczewski J, Hendrix MJ. Embryonic and tumorigenic pathways converge via Nodal signaling: role in melanoma aggressiveness. Nat Med. 2006;12:925-32.
-
(2006)
Nat Med
, vol.12
, pp. 925-932
-
-
Topczewska, J.M.1
Postovit, L.M.2
Margaryan, N.V.3
Sam, A.4
Hess, A.R.5
Wheaton, W.W.6
Nickoloff, B.J.7
Topczewski, J.8
Hendrix, M.J.9
-
12
-
-
8744286786
-
Nodal induces apoptosis and inhibits proliferation in human epithelial ovarian cancer cells via activin receptor-like kinase 7
-
Xu G, Zhong Y, Munir S, Yang BB, Tsang BK, Peng C. Nodal induces apoptosis and inhibits proliferation in human epithelial ovarian cancer cells via activin receptor-like kinase 7. J Clin Endocrinol Metab. 2004;89:5523-34.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 5523-5534
-
-
Xu, G.1
Zhong, Y.2
Munir, S.3
Yang, B.B.4
Tsang, B.K.5
Peng, C.6
-
13
-
-
33646128737
-
Activin receptor-like kinase 7 induces apoptosis through up-regulation of Bax and down-regulation of Xiap in normal and malignant ovarian epithelial cell lines
-
Xu G, Zhou H, Wang Q, Auersperg N, Peng C. Activin receptor-like kinase 7 induces apoptosis through up-regulation of Bax and down-regulation of Xiap in normal and malignant ovarian epithelial cell lines. Mol Cancer Res. 2006;4:235-46.
-
(2006)
Mol Cancer Res
, vol.4
, pp. 235-246
-
-
Xu, G.1
Zhou, H.2
Wang, Q.3
Auersperg, N.4
Peng, C.5
-
14
-
-
79551553893
-
MicroRNA 376c enhances ovarian cancer cell survival by targeting activin receptor-like kinase 7: implications for chemoresistance
-
Ye G, Fu G, Cui S, Zhao S, Bernaudo S, Bai Y, Ding Y, Zhang Y, Yang BB, Peng C. MicroRNA 376c enhances ovarian cancer cell survival by targeting activin receptor-like kinase 7: implications for chemoresistance. J Cell Sci. 2011;124:359-68.
-
(2011)
J Cell Sci
, vol.124
, pp. 359-368
-
-
Ye, G.1
Fu, G.2
Cui, S.3
Zhao, S.4
Bernaudo, S.5
Bai, Y.6
Ding, Y.7
Zhang, Y.8
Yang, B.B.9
Peng, C.10
-
15
-
-
77953412947
-
Nodal and activin receptor-like kinase 7 induce apoptosis in human breast cancer cell lines: role of caspase 3
-
Zhong Y, Xu G, Ye G, Lee D, Modica-Amore J, Peng C. Nodal and activin receptor-like kinase 7 induce apoptosis in human breast cancer cell lines: role of caspase 3. Int J Physiol Pathophysiol Pharmacol. 2009;1:83-96.
-
(2009)
Int J Physiol Pathophysiol Pharmacol
, vol.1
, pp. 83-96
-
-
Zhong, Y.1
Xu, G.2
Ye, G.3
Lee, D.4
Modica-Amore, J.5
Peng, C.6
-
16
-
-
80053323667
-
Glioblastoma cells: a heterogeneous and fatal tumor interacting with the parenchyma
-
Alves TR, Lima FR, Kahn SA, Lobo D, Dubois LG, Soletti R, Borges H, Neto VM. Glioblastoma cells: a heterogeneous and fatal tumor interacting with the parenchyma. Life Sci. 2011;89:532-9.
-
(2011)
Life Sci
, vol.89
, pp. 532-539
-
-
Alves, T.R.1
Lima, F.R.2
Kahn, S.A.3
Lobo, D.4
Dubois, L.G.5
Soletti, R.6
Borges, H.7
Neto, V.M.8
-
17
-
-
84862316690
-
Glioblastoma: therapeutic challenges, what lies ahead
-
Lima FR, Kahn SA, Soletti RC, Biasoli D, Alves T, da Fonseca AC, Garcia C, Romao L, Brito J, Holanda-Afonso R, Faria J, Borges H, Moura-Neto V. Glioblastoma: therapeutic challenges, what lies ahead. Biochim Biophys Acta. 1826;2012:338-49.
-
(1826)
Biochim Biophys Acta
, vol.2012
, pp. 338-349
-
-
Lima, F.R.1
Kahn, S.A.2
Soletti, R.C.3
Biasoli, D.4
Alves, T.5
Fonseca, A.C.6
Garcia, C.7
Romao, L.8
Brito, J.9
Holanda-Afonso, R.10
Faria, J.11
Borges, H.12
Moura-Neto, V.13
-
18
-
-
0034987702
-
Malignant glioma: genetics and biology of a grave matter
-
Maher EA, Furnari FB, Bachoo RM, Rowitch DH, Louis DN, Cavenee WK, DePinho RA. Malignant glioma: genetics and biology of a grave matter. Genes Dev. 2001;15:1311-33.
-
(2001)
Genes Dev
, vol.15
, pp. 1311-1333
-
-
Maher, E.A.1
Furnari, F.B.2
Bachoo, R.M.3
Rowitch, D.H.4
Louis, D.N.5
Cavenee, W.K.6
DePinho, R.A.7
-
19
-
-
70449099233
-
Brain cancer propagating cells: biology, genetics and targeted therapies
-
Hadjipanayis CG, Van Meir EG. Brain cancer propagating cells: biology, genetics and targeted therapies. Trends Mol Med. 2009;15:519-30.
-
(2009)
Trends Mol Med
, vol.15
, pp. 519-530
-
-
Hadjipanayis, C.G.1
Meir, E.G.2
-
20
-
-
4944250781
-
Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma
-
Galli R, Binda E, Orfanelli U, Cipelletti B, Gritti A, De Vitis S, Fiocco R, Foroni C, Dimeco F, Vescovi A. Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma. Cancer Res. 2004;64:7011-21.
-
(2004)
Cancer Res
, vol.64
, pp. 7011-7021
-
-
Galli, R.1
Binda, E.2
Orfanelli, U.3
Cipelletti, B.4
Gritti, A.5
Vitis, S.6
Fiocco, R.7
Foroni, C.8
Dimeco, F.9
Vescovi, A.10
-
21
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, Hide T, Henkelman RM, Cusimano MD, Dirks PB. Identification of human brain tumour initiating cells. Nature. 2004;432:396-401.
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
Squire, J.A.4
Bayani, J.5
Hide, T.6
Henkelman, R.M.7
Cusimano, M.D.8
Dirks, P.B.9
-
22
-
-
84873410837
-
Glioblastoma cancer stem cells: role of the microenvironment and therapeutic targeting
-
Persano L, Rampazzo E, Basso G, Viola G. Glioblastoma cancer stem cells: role of the microenvironment and therapeutic targeting. Biochem Pharmacol. 2013;85:612-22.
-
(2013)
Biochem Pharmacol
, vol.85
, pp. 612-622
-
-
Persano, L.1
Rampazzo, E.2
Basso, G.3
Viola, G.4
-
23
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, Hjelmeland AB, Dewhirst MW, Bigner DD, Rich JN. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature. 2006;444:756-60.
-
(2006)
Nature
, vol.444
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
Hao, Y.4
Shi, Q.5
Hjelmeland, A.B.6
Dewhirst, M.W.7
Bigner, D.D.8
Rich, J.N.9
-
24
-
-
64749093574
-
Association of reactive oxygen species levels and radioresistance in cancer stem cells
-
Diehn M, Cho RW, Lobo NA, Kalisky T, Dorie MJ, Kulp AN, Qian D, Lam JS, Ailles LE, Wong M, Joshua B, Kaplan MJ, Wapnir I, Dirbas FM, Somlo G, Garberoglio C, Paz B, Shen J, Lau SK, Quake SR, Brown JM, Weissman IL, Clarke MF. Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature. 2009;458:780-3.
-
(2009)
Nature
, vol.458
, pp. 780-783
-
-
Diehn, M.1
Cho, R.W.2
Lobo, N.A.3
Kalisky, T.4
Dorie, M.J.5
Kulp, A.N.6
Qian, D.7
Lam, J.S.8
Ailles, L.E.9
Wong, M.10
Joshua, B.11
Kaplan, M.J.12
Wapnir, I.13
Dirbas, F.M.14
Somlo, G.15
Garberoglio, C.16
Paz, B.17
Shen, J.18
Lau, S.K.19
Quake, S.R.20
Brown, J.M.21
Weissman, I.L.22
Clarke, M.F.23
more..
-
25
-
-
16844368698
-
Tumour stem cells and drug resistance
-
Dean M, Fojo T, Bates S. Tumour stem cells and drug resistance. Nat Rev Cancer. 2005;5:275-84.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 275-284
-
-
Dean, M.1
Fojo, T.2
Bates, S.3
-
26
-
-
84874928706
-
Equinatoxin II potentiates temozolomide- and etoposide-induced glioblastoma cell death
-
Kahn SA, Biasoli D, Garcia C, Geraldo LH, Pontes B, Sobrinho M, Frauches AC, Romao L, Soletti RC, Assuncao Fdos S, Tovar-Moll F, de Souza JM, Lima FR, Anderluh G, Moura-neto V. Equinatoxin II potentiates temozolomide- and etoposide-induced glioblastoma cell death. Curr Top Med Chem. 2012;12:2082-93.
-
(2012)
Curr Top Med Chem
, vol.12
, pp. 2082-2093
-
-
Kahn, S.A.1
Biasoli, D.2
Garcia, C.3
Geraldo, L.H.4
Pontes, B.5
Sobrinho, M.6
Frauches, A.C.7
Romao, L.8
Soletti, R.C.9
Assuncao Fdos, S.10
Tovar-Moll, F.11
Souza, J.M.12
Lima, F.R.13
Anderluh, G.14
Moura-neto, V.15
-
27
-
-
33845546332
-
Moura Neto V. Interactive properties of human glioblastoma cells with brain neurons in culture and neuronal modulation of glial laminin organization
-
Faria J, Romao L, Martins S, Alves T, Mendes FA, de Faria GP, Hollanda R, Takiya C, Chimelli L, Morandi V, de Souza JM, Abreu JG. Moura Neto V. Interactive properties of human glioblastoma cells with brain neurons in culture and neuronal modulation of glial laminin organization. Differentiation. 2006;74:562-72.
-
(2006)
Differentiation
, vol.74
, pp. 562-572
-
-
Faria, J.1
Romao, L.2
Martins, S.3
Alves, T.4
Mendes, F.A.5
Faria, G.P.6
Hollanda, R.7
Takiya, C.8
Chimelli, L.9
Morandi, V.10
Souza, J.M.11
Abreu, J.G.12
-
28
-
-
84882608216
-
Retinoblastoma protein regulates the crosstalk between autophagy and apoptosis, and favors glioblastoma resistance to etoposide
-
Biasoli D, Kahn SA, Cornelio TA, Furtado M, Campanati L, Chneiweiss H, Moura-Neto V, Borges HL. Retinoblastoma protein regulates the crosstalk between autophagy and apoptosis, and favors glioblastoma resistance to etoposide. Cell Death Dis. 2013;4:e767.
-
(2013)
Cell Death Dis
, vol.4
-
-
Biasoli, D.1
Kahn, S.A.2
Cornelio, T.A.3
Furtado, M.4
Campanati, L.5
Chneiweiss, H.6
Moura-Neto, V.7
Borges, H.L.8
-
29
-
-
53549099123
-
The prognostic value of nestin expression in newly diagnosed glioblastoma: report from the Radiation Therapy Oncology Group
-
Chinnaiyan P, Wang M, Rojiani AM, Tofilon PJ, Chakravarti A, Ang KK, Zhang HZ, Hammond E, Curran W Jr, Mehta MP. The prognostic value of nestin expression in newly diagnosed glioblastoma: report from the Radiation Therapy Oncology Group. Radiat Oncol. 2008;3:32.
-
(2008)
Radiat Oncol
, vol.3
, pp. 32
-
-
Chinnaiyan, P.1
Wang, M.2
Rojiani, A.M.3
Tofilon, P.J.4
Chakravarti, A.5
Ang, K.K.6
Zhang, H.Z.7
Hammond, E.8
Curran, W.9
Mehta, M.P.10
-
30
-
-
58249094759
-
Cripto localizes Nodal at the limiting membrane of early endosomes
-
ra13
-
Blanchet MH, Le Good JA, Oorschot V, Baflast S, Minchiotti G, Klumperman J, Constam DB. Cripto localizes Nodal at the limiting membrane of early endosomes. Sci Signal. 2008;1:ra13.
-
(2008)
Sci Signal.
, vol.1
-
-
Blanchet, M.H.1
Le Good, J.A.2
Oorschot, V.3
Baflast, S.4
Minchiotti, G.5
Klumperman, J.6
Constam, D.B.7
-
31
-
-
84865365335
-
Rab GTPases regulating receptor trafficking at the late endosome-lysosome membranes
-
Ng EL, Gan BQ, Ng F, Tang BL. Rab GTPases regulating receptor trafficking at the late endosome-lysosome membranes. Cell Biochem Funct. 2012;30:515-23.
-
(2012)
Cell Biochem Funct
, vol.30
, pp. 515-523
-
-
Ng, E.L.1
Gan, B.Q.2
Ng, F.3
Tang, B.L.4
-
32
-
-
80052233389
-
Endosome maturation
-
Huotari J, Helenius A. Endosome maturation. EMBO J. 2011;30:3481-500.
-
(2011)
EMBO J
, vol.30
, pp. 3481-3500
-
-
Huotari, J.1
Helenius, A.2
-
33
-
-
84867084482
-
The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling
-
Sandri C, Caccavari F, Valdembri D, Camillo C, Veltel S, Santambrogio M, Lanzetti L, Bussolino F, Ivaska J, Serini G. The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling. Cell Res. 2012;22:1479-501.
-
(2012)
Cell Res
, vol.22
, pp. 1479-1501
-
-
Sandri, C.1
Caccavari, F.2
Valdembri, D.3
Camillo, C.4
Veltel, S.5
Santambrogio, M.6
Lanzetti, L.7
Bussolino, F.8
Ivaska, J.9
Serini, G.10
-
34
-
-
84904701296
-
A RAB5/RAB4 recycling circuitry induces a proteolytic invasive program and promotes tumor dissemination
-
Frittoli E, Palamidessi A, Marighetti P, Confalonieri S, Bianchi F, Malinverno C, Mazzarol G, Viale G, Martin-Padura I, Garre M, Parazzoli D, Mattei V, Cortellino S, Bertalot G, Di Fiore PP, Scita G. A RAB5/RAB4 recycling circuitry induces a proteolytic invasive program and promotes tumor dissemination. J Cell Biol. 2014;206:307-28.
-
(2014)
J Cell Biol
, vol.206
, pp. 307-328
-
-
Frittoli, E.1
Palamidessi, A.2
Marighetti, P.3
Confalonieri, S.4
Bianchi, F.5
Malinverno, C.6
Mazzarol, G.7
Viale, G.8
Martin-Padura, I.9
Garre, M.10
Parazzoli, D.11
Mattei, V.12
Cortellino, S.13
Bertalot, G.14
Fiore, P.P.15
Scita, G.16
-
35
-
-
84901450867
-
Rab'ing tumor cell migration and invasion: focal adhesion disassembly driven by Rab5
-
Torres VA. Rab'ing tumor cell migration and invasion: focal adhesion disassembly driven by Rab5. Cell Adh Migr. 2014;8:84-7.
-
(2014)
Cell Adh Migr
, vol.8
, pp. 84-87
-
-
Torres, V.A.1
-
37
-
-
33947656333
-
Nodal signaling: developmental roles and regulation
-
Shen MM. Nodal signaling: developmental roles and regulation. Development. 2007;134:1023-34.
-
(2007)
Development
, vol.134
, pp. 1023-1034
-
-
Shen, M.M.1
-
38
-
-
67249150119
-
Rab7: roles in membrane trafficking and disease
-
Zhang M, Chen L, Wang S, Wang T. Rab7: roles in membrane trafficking and disease. Biosci Rep. 2009;29:193-209.
-
(2009)
Biosci Rep
, vol.29
, pp. 193-209
-
-
Zhang, M.1
Chen, L.2
Wang, S.3
Wang, T.4
-
39
-
-
14244262504
-
Nodal inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway
-
Vallier L, Reynolds D, Pedersen RA. Nodal inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway. Dev Biol. 2004;275:403-21.
-
(2004)
Dev Biol
, vol.275
, pp. 403-421
-
-
Vallier, L.1
Reynolds, D.2
Pedersen, R.A.3
|