A RAB5/RAB4 recycling circuitry induces a proteolytic invasive program and promotes tumor dissemination

Journal of Cell Biology

Volumn 206, Issue 2, 2014, Pages 307-328

  Frittoli, Emanuela ^a   Palamidessi, Andrea ^a   Marighetti, Paola ^a   Confalonieri, Stefano ^a,b   Bianchi, Fabrizio ^b   Malinverno, Chiara ^a   Mazzaro, Giovanni ^a,b   Viale, Giuseppe ^b   Martin Padura, Giuseppe ^b   Garré, Massimilliano ^a   Parazzoli, Dario ^a   Mattei, Valentina ^b   Cortellino, Salvatore ^a   Bertalot, Giovanni ^b   Di Fiore, Pier Paolo ^a,b,c   Scita, Giorgio ^a,c  

^a FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^b EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BETA3 INTEGRIN; MATRIX METALLOPROTEINASE 14; MEMBRANE TYPE 1 MATRIX METALLOPROTEASE; METALLOPROTEINASE; RAB 4 PROTEIN; RAB 5A PROTEIN; RAB PROTEIN; SCATTER FACTOR; UNCLASSIFIED DRUG;

AGGRESSION; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BREAST CANCER; BREAST CANCER CELL LINE; BREAST CARCINOMA; CELL INVASION; CELL MOTILITY; CHEMOTAXIS; CONTROLLED STUDY; ENDOCYTOSIS; EXTRACELLULAR MATRIX; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; INTRADUCTAL CARCINOMA; LYMPH NODE METASTASIS; MACROPHAGE; MAMMARY GLAND; METASTASIS; MOUSE; NONHUMAN; PRIMARY TUMOR; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; DISEASE PROGRESSION; EXTRACELLULAR MATRIX; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICE; NEOPLASM INVASIVENESS; NEOPLASM RECURRENCE, LOCAL; PROTEOLYSIS; RAB5 GTP-BINDING PROTEINS; TRANSPLANTATION, HETEROLOGOUS;

EID: 84904701296     PISSN: 00219525     EISSN: 15408140     Source Type: Journal    
DOI: 10.1083/jcb.201403127     Document Type: Article

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