MiRNA-375 a Sensor of Glucotoxicity Is Altered in the Serum of Children with Newly Diagnosed Type 1 Diabetes

Journal of Diabetes Research

Volumn 2016, Issue , 2016, Pages

  Marchand, Lucien ^a,b   Jalabert, Audrey ^a   Meugnier, Emmanuelle ^a   Van Den Hende, Kathleen ^c   Fabien, Nicole ^b   Nicolino, Marc ^a,c   Madec, Anne Marie ^a   Thivolet, Charles ^a,b   Rome, Sophie ^a  

^a UNIVERSITÉ DE LYON   (France)

^b CENTRE HOSPITALIER LYON SUD   (France)

^c HOSPICES CIVILS DE LYON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; GLUCOSE; HEMOGLOBIN A1C; INSULIN; MICRORNA 10A; MICRORNA 1197; MICRORNA 212; MICRORNA 23A; MICRORNA 23B; MICRORNA 27A; MICRORNA 30; MICRORNA 30D; MICRORNA 320B; MICRORNA 375; MICRORNA 485 3P; MICRORNA 519A; MICRORNA 627; UNCLASSIFIED DRUG; MICRORNA; MIRN375 MICRORNA, HUMAN;

ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOTOXICITY; HEMOLYSIS; HOMEOSTASIS AND REGULATION; HUMAN; HUMAN CELL; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; INSULIN TREATMENT; MALE; PANCREAS ISLET BETA CELL; PANCREAS SECRETION; PROTEIN METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; ADOLESCENT; BLOOD; DRUG EFFECTS; METABOLISM; PANCREAS ISLET;

ADOLESCENT; CHILD; DIABETES MELLITUS, TYPE 1; DOWN-REGULATION; FEMALE; GLUCOSE; HUMANS; ISLETS OF LANGERHANS; MALE; MICRORNAS;

EID: 84975158997     PISSN: 23146745     EISSN: 23146753     Source Type: Journal    
DOI: 10.1155/2016/1869082     Document Type: Article

References (41)

1. M. A. Atkinson, G. S. Eisenbarth, and A. W. Michels, "Type 1 diabetes, " The Lancet, vol. 383, no. 9911, pp. 69-82, 2014.
2. B. Buckingham, R. W. Beck, K. J. Ruedy et al., "Effectiveness of early intensive therapy onb-cell preservation in type 1 diabetes, " Diabetes Care, vol. 36, no. 12, pp. 4030-4035, 2013.
3. P. In't Veld, "Insulitis in human type 1 diabetes: A comparison between patients and animal models, " Seminars in Immunopathology, vol. 36, no. 5, pp. 569-579, 2014.
4. A. Willcox, S. J. Richardson, A. J. Bone, A. K. Foulis, and N. G. Morgan, "Analysis of islet inflammation in human type 1 diabetes, " Clinical & Experimental Immunology, vol. 155, no. 2, pp. 173-181, 2009.
5. M. Campbell-Thompson, C. Wasserfall, J. Kaddis et al., "Network for Pancreatic Organ Donors with Diabetes (nPOD): developing a tissue biobank for type 1 diabetes, " Diabetes/Metabolism Research and Reviews, vol. 28, no. 7, pp. 608-617, 2012.
6. D. P. Bartel, "MicroRNAs: genomics, biogenesis, mechanism, and function, " Cell, vol. 116, no. 2, pp. 281-297, 2004.
7. J. A. Weber, D. H. Baxter, S. Zhang et al., "The microRNA spectrum in 12 body fluids, " Clinical Chemistry, vol. 56, no. 11, pp. 1733-1741, 2010.
8. K. Wang, S. Zhang, B. Marzolf et al., "Circulating microRNAs, potential biomarkers for drug-induced liver injury, " Proceedings of the National Academy of Sciences of the United States of America, vol. 106, no. 11, pp. 4402-4407, 2009.
9. L. N. L. Van Aelst and S. Heymans, "MicroRNAs as biomarkers for ischemic heart disease, " Journal of Cardiovascular Translational Research, vol. 6, no. 4, pp. 458-470, 2013.
10. M. Ferracin, A. Veronese, and M. Negrini, "Micromarkers: miRNAs in cancer diagnosis and prognosis, " Expert Review of Molecular Diagnostics, vol. 10, no. 3, pp. 297-308, 2010.
11. H. Geekiyanage, G. A. Jicha, P. T. Nelson, and C. Chan, "Blood serum miRNA: non-invasive biomarkers for Alzheimer's disease, " Experimental Neurology, vol. 235, no. 2, pp. 491-496, 2012.
12. R. M. O'Connell, D. S. Rao, and D. Baltimore, "microRNA regulation of inflammatory responses, " Annual Review of Immunology, vol. 30, pp. 295-312, 2012.
13. A. Villard, L. Marchand, C. Thivolet, and S. Rome, "Diagnostic value of cell-free circulating micrornas for obesity and type 2 diabetes: A meta-analysis, " Journal of Molecular Biomarkers & Diagnosis, vol. 6, article 251, 2015.
14. L. B. Nielsen, C. Wang, K. Sørensen et al., "Circulating levels of microRNA from children with newly diagnosed type 1 diabetes and healthy controls: evidence that miR-25 associates to residual beta-cell function and glycaemic control during disease progression, " Experimental Diabetes Research, vol. 2012, Article ID 896362, 7 pages, 2012.
15. J. Osipova, D.-C. Fischer, S. Dangwal et al., "Diabetes-associated microRNAs in pediatric patients with type 1 diabetes mellitus: A cross-sectional cohort study, " Journal of Clinical Endocrinology and Metabolism, vol. 99, no. 9, pp. E1661-E1665, 2014.
16. M. N. Poy, L. Eliasson, J. Krutzfeldt et al., "A pancreatic isletspecific microRNAregulates insulin secretion, " Nature, vol. 432, no. 7014, pp. 226-230, 2004.
17. M. N. Poy, J. Hausser, M. Trajkovski et al., "miR-375 maintains normal pancreatic alpha-and beta-cell mass, " Proceedings of the National Academy of Sciences of the United States of America, vol. 106, no. 14, pp. 5813-5818, 2009.
18. V. A. Salunkhe, J. L. S. Esguerra, J. K. Ofori et al., "Modulation of microRNA-375 expression alters voltage-gated Na+ channel properties and exocytosis in insulin-secreting cells, " Acta Physiologica, vol. 213, no. 4, pp. 882-892, 2015.
19. J. Hoseki, R. Ushioda, and K. Nagata, "Mechanism and components of endoplasmic reticulum-associated degradation, " Journal of Biochemistry, vol. 147, no. 1, pp. 19-25, 2010.
20. A. Deo, J. Carlsson, and A. Lindlöf, "How to choose a normalization strategy for miRNA quantitative real-time (qPCR) arrays, " Journal of Bioinformatics and Computational Biology, vol. 9, no. 6, pp. 795-812, 2011.
21. J. L. S. Esguerra, C. Bolmeson, C. M. Cilio, and L. Eliasson, "Differential glucose-regulation of microRNAs in pancreatic islets of non-obese type 2 diabetes model Goto-Kakizaki rat, " PLoS ONE, vol. 6, no. 4, Article ID e18613, 2011.
22. J. C. Coggeshall, J. P. Heggers, M. C. Robson, and H. Baker, "Biotin status and plasma glucose in diabetics, " Annals of the New York Academy of Sciences, vol. 447, no. 1, pp. 389-392, 1985.
23. E. Boslem, P. J. Meikle, and T. J. Biden, "Roles of ceramide and sphingolipids in pancreatic-cell function and dysfunction, " Islets, vol. 4, no. 3, pp. 177-187, 2012.
24. S. Erener, M. Mojibian, J. K. Fox, H. C. Denroche, and T. J. Kieffer, "Circulating miR-375 as a biomarker of-cell death and diabetes in mice, " Endocrinology, vol. 154, no. 2, pp. 603-608, 2013.
25. M. van de Bunt, K. J. Gaulton, L. Parts et al., "ThemiRNAprofile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis, " PLoS ONE, vol. 8, no. 1, article e55272, 2013.
26. E. Flowers, G. Y. Won, and Y. Fukuoka, "Micrornas associated with exercise and diet: A systematic review, " Physiological Genomics, vol. 47, no. 1, pp. 1-11, 2015.
27. L. Kong, J. Zhu, W. Han et al., "Significance of serum microRNAs in pre-diabetes and newly diagnosed type 2 diabetes: A clinical study, " Acta Diabetologica, vol. 48, no. 1, pp. 61-69, 2011.
28. G. Carreras-Badosa, A. Bonmatí, F. J. Ortega et al., "Altered circulating miRNA expression profile in pregestational and gestational obesity, " The Journal of Clinical Endocrinology & Metabolism, vol. 100, no. 11, pp. E1446-E1456, 2015.
29. M. Latreille, K. Herrmanns, N. Renwick et al., "miR-375 gene dosage in pancreatic-cells: implications for regulation of-cell mass and biomarker development, " Journal of Molecular Medicine, vol. 93, no. 10, pp. 1159-1169, 2015.
30. C. Higuchi, A. Nakatsuka, J. Eguchi et al., "Identification of circulating miR-101, miR-375 and miR-802 as biomarkers for type 2 diabetes, "Metabolism: Clinical and Experimental, vol. 64, no. 4, pp. 489-497, 2015.
31. D. S. Karolina, A. Armugam, S. Tavintharan et al., "MicroRNA 144 impairs insulin signaling by inhibiting the expression of insulin receptor substrate 1 in type 2 diabetes mellitus, " PLoS ONE, vol. 6, no. 8, Article ID e22839, 2011.
32. C. Guay, V. Menoud, S. Rome, and R. Regazzi, "Horizontal transfer of exosomal microRNAs transduce apoptotic signals between pancreatic beta-cells, " Cell Communication and Signaling, vol. 13, no. 1, article 17, 2015.
33. M. Latreille, K. Herrmanns, N. Renwick et al., "miR-375 gene dosage in pancreatic-cells: implications for regulation of-cell mass and biomarker development, " Journal of Molecular Medicine, vol. 93, no. 10, pp. 1159-1169, 2015.
34. Y. Liang, D. Ridzon, L. Wong, and C. Chen, "Characterization of microRNA expression profiles in normal human tissues, " BMC Genomics, vol. 8, article 166, 2007.
35. P. Fiorina, A. M. J. Shapiro, C. Ricordi, and A. Secchi, "The clinical impact of islet transplantation, " American Journal of Transplantation, vol. 8, no. 10, pp. 1990-1997, 2008.
36. M. J. I. Ansari, P. Fiorina, S. Dada et al., "Role of ICOS pathway in autoimmune and alloimmune responses in NOD mice, " Clinical Immunology, vol. 126, no. 2, pp. 140-147, 2008.
37. P. Fiorina, A. Vergani, S. Dada et al., "Targeting CD22 reprograms B-cells and reverses autoimmune diabetes, " Diabetes, vol. 57, no. 11, pp. 3013-3024, 2008.
38. A. Vergani, F. D'Addio, M. Jurewicz et al., "A novel clinically relevant strategy to abrogate autoimmunity and regulate alloimmunity in NOD mice, " Diabetes, vol. 59, no. 9, pp. 2253-2264, 2010.
39. F. Reynier, A. Pachot, M. Paye et al., "Specific gene expression signature associated with development of autoimmune type-I diabetes using whole-blood microarray analysis, " Genes and Immunity, vol. 11, no. 3, pp. 269-278, 2010.
40. M. A. Atkinson, M. von Herrath, A. C. Powers, and M. Clare-Salzler, "Current concepts on the pathogenesis of type 1 diabetes-considerations for attempts to prevent and reverse the disease, " Diabetes Care, vol. 38, no. 6, pp. 979-988, 2015.
41. L.-M. Li, Z.-B. Hu, Z.-X. Zhou et al., "Serum microRNA profiles serve as novel biomarkers for HBV infection and diagnosis of HBV-positive hepatocarcinoma, " Cancer Research, vol. 70, no. 23, pp. 9798-9807, 2010.