-
1
-
-
84255197842
-
Cancer immunotherapy comes of age
-
Mellman I, Coukos G, Dranoff G. Cancer immunotherapy comes of age. Nature 2011;480:480-9.
-
(2011)
Nature
, vol.480
, pp. 480-489
-
-
Mellman, I.1
Coukos, G.2
Dranoff, G.3
-
2
-
-
84920545991
-
Cancer immunotherapy and breaking immune tolerance: New approaches to an old challenge
-
Makkouk A, Weiner GJ. Cancer immunotherapy and breaking immune tolerance: new approaches to an old challenge. Cancer Res 2015;75:5-10.
-
(2015)
Cancer Res
, vol.75
, pp. 5-10
-
-
Makkouk, A.1
Weiner, G.J.2
-
3
-
-
84941280057
-
Beyond CTLA-4 and PD-1, the generation Z of negative checkpoint regulators
-
Le Mercier I, Lines JL, Noelle RJ. Beyond CTLA-4 and PD-1, the generation Z of negative checkpoint regulators. Front Immunol 2015;6:418.
-
(2015)
Front Immunol
, vol.6
, pp. 418
-
-
Le Mercier, I.1
Lines, J.L.2
Noelle, R.J.3
-
4
-
-
85012977495
-
Up-regulation of Tim-3 is associated with poor prognosis of patients with colon cancer
-
Zhou E, Huang Q, Wang J, Fang C, Yang L, Zhu M, et al. Up-regulation of Tim-3 is associated with poor prognosis of patients with colon cancer. Int J Clin Exp Pathol 2015;8:8018-27.
-
(2015)
Int J Clin Exp Pathol
, vol.8
, pp. 8018-8027
-
-
Zhou, E.1
Huang, Q.2
Wang, J.3
Fang, C.4
Yang, L.5
Zhu, M.6
-
5
-
-
0029947568
-
Enhancement of antitumor immunity by CTLA-4 blockade
-
Leach DR, Krummel MF, Allison JP. Enhancement of antitumor immunity by CTLA-4 blockade. Science 1996;271:1734-6.
-
(1996)
Science
, vol.271
, pp. 1734-1736
-
-
Leach, D.R.1
Krummel, M.F.2
Allison, J.P.3
-
6
-
-
17944364189
-
Elucidating the autoimmune and antitumor effector mechanisms of a treatment based on cytotoxic T lymphocyte antigen-4 blockade in combination with a B16 melanoma vaccine: Comparison of prophylaxis and therapy
-
van Elsas A, Sutmuller RP, Hurwitz AA, Ziskin J, Villasenor J, Medema JP, et al. Elucidating the autoimmune and antitumor effector mechanisms of a treatment based on cytotoxic T lymphocyte antigen-4 blockade in combination with a B16 melanoma vaccine: comparison of prophylaxis and therapy. J Exp Med 2001;194:481-9.
-
(2001)
J Exp Med
, vol.194
, pp. 481-489
-
-
Van Elsas, A.1
Sutmuller, R.P.2
Hurwitz, A.A.3
Ziskin, J.4
Villasenor, J.5
Medema, J.P.6
-
7
-
-
0037126021
-
Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
-
Iwai Y, Ishida M, Tanaka Y, Okazaki T, Honjo T, Minato N. Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade. Proc Natl Acad Sci U S A 2002;99:12293-7.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 12293-12297
-
-
Iwai, Y.1
Ishida, M.2
Tanaka, Y.3
Okazaki, T.4
Honjo, T.5
Minato, N.6
-
8
-
-
32644467549
-
Antitumor activity in melanoma and anti-self responses in a phase I trial with the anti-cytotoxic T lymphocyte-associated antigen 4 monoclonal antibody CP-675,206
-
Ribas A, Camacho LH, Lopez-Berestein G, Pavlov D, Bulanhagui CA, Millham R, et al. Antitumor activity in melanoma and anti-self responses in a phase I trial with the anti-cytotoxic T lymphocyte-associated antigen 4 monoclonal antibody CP-675,206. J Clin Oncol 2005;23:8968-77.
-
(2005)
J Clin Oncol
, vol.23
, pp. 8968-8977
-
-
Ribas, A.1
Camacho, L.H.2
Lopez-Berestein, G.3
Pavlov, D.4
Bulanhagui, C.A.5
Millham, R.6
-
9
-
-
20744432041
-
Tumor immunotherapy: Preclinical and clinical activity of anti-CTLA4 antibodies
-
Korman A, Yellin M, Keler T. Tumor immunotherapy: preclinical and clinical activity of anti-CTLA4 antibodies. Curr Opin Investig Drugs 2005;6:582-91.
-
(2005)
Curr Opin Investig Drugs
, vol.6
, pp. 582-591
-
-
Korman, A.1
Yellin, M.2
Keler, T.3
-
10
-
-
77954956787
-
Current experience with CTLA4-blocking monoclonal antibodies for the treatment of solid tumors
-
Agarwala SS, Ribas A. Current experience with CTLA4-blocking monoclonal antibodies for the treatment of solid tumors. J Immunother 2010;33:557-69.
-
(2010)
J Immunother
, vol.33
, pp. 557-569
-
-
Agarwala, S.S.1
Ribas, A.2
-
11
-
-
84925529257
-
Human cancer immunotherapy with antibodies to the PD-1 and PD-L1 pathway
-
Ohaegbulam KC, Assal A, Lazar-Molnar E, Yao Y, Zang X. Human cancer immunotherapy with antibodies to the PD-1 and PD-L1 pathway. Trends Mol Med 2015;21:24-33.
-
(2015)
Trends Mol Med
, vol.21
, pp. 24-33
-
-
Ohaegbulam, K.C.1
Assal, A.2
Lazar-Molnar, E.3
Yao, Y.4
Zang, X.5
-
12
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 2012;366:2443-54.
-
(2012)
N Engl J Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
-
13
-
-
49649114804
-
Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies
-
Berger R, Rotem-Yehudar R, Slama G, Landes S, Kneller A, Leiba M, et al. Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies. Clin Cancer Res 2008;14:3044-51.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3044-3051
-
-
Berger, R.1
Rotem-Yehudar, R.2
Slama, G.3
Landes, S.4
Kneller, A.5
Leiba, M.6
-
14
-
-
20244384862
-
Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer
-
Ohigashi Y, Sho M, Yamada Y, Tsurui Y, Hamada K, Ikeda N, et al. Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer. Clin Cancer Res 2005;11:2947-53.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 2947-2953
-
-
Ohigashi, Y.1
Sho, M.2
Yamada, Y.3
Tsurui, Y.4
Hamada, K.5
Ikeda, N.6
-
15
-
-
78650621479
-
PD-1 and PD-L1 upregulation promotes CD8(+) T-cell apoptosis and postoperative recurrence in hepatocellular carcinoma patients
-
Shi F, Shi M, Zeng Z, Qi RZ, Liu ZW, Zhang JY, et al. PD-1 and PD-L1 upregulation promotes CD8(+) T-cell apoptosis and postoperative recurrence in hepatocellular carcinoma patients. Int J Cancer 2011;128:887-96.
-
(2011)
Int J Cancer
, vol.128
, pp. 887-896
-
-
Shi, F.1
Shi, M.2
Zeng, Z.3
Qi, R.Z.4
Liu, Z.W.5
Zhang, J.Y.6
-
16
-
-
84879104519
-
Dual blockade of PD-1 and CTLA-4 combined with tumor vaccine effectively restores T-cell rejection function in tumors
-
Duraiswamy J, Kaluza KM, Freeman GJ, Coukos G. Dual blockade of PD-1 and CTLA-4 combined with tumor vaccine effectively restores T-cell rejection function in tumors. Cancer Res 2013;73:3591-603.
-
(2013)
Cancer Res
, vol.73
, pp. 3591-3603
-
-
Duraiswamy, J.1
Kaluza, K.M.2
Freeman, G.J.3
Coukos, G.4
-
17
-
-
84879579673
-
At the bench: Preclinical rationale for CTLA-4 and PD-1 blockade as cancer immunotherapy
-
Intlekofer AM, Thompson CB. At the bench: preclinical rationale for CTLA-4 and PD-1 blockade as cancer immunotherapy. J Leukoc Biol 2013;94:25-39.
-
(2013)
J Leukoc Biol
, vol.94
, pp. 25-39
-
-
Intlekofer, A.M.1
Thompson, C.B.2
-
19
-
-
84892746507
-
Caspase-1: The inflammasome and beyond
-
Sollberger G, Strittmatter GE, Garstkiewicz M, Sand J, Beer HD. Caspase-1: the inflammasome and beyond. Innate Immun 2014;20:115-25.
-
(2014)
Innate Immun
, vol.20
, pp. 115-125
-
-
Sollberger, G.1
Strittmatter, G.E.2
Garstkiewicz, M.3
Sand, J.4
Beer, H.D.5
-
20
-
-
84858643750
-
Inflammasomes in carcinogenesis and anticancer immune responses
-
Zitvogel L, Kepp O, Galluzzi L, Kroemer G. Inflammasomes in carcinogenesis and anticancer immune responses. Nat Immunol 2012;13:343-51.
-
(2012)
Nat Immunol
, vol.13
, pp. 343-351
-
-
Zitvogel, L.1
Kepp, O.2
Galluzzi, L.3
Kroemer, G.4
-
21
-
-
84895168155
-
Inflammasomes in cancer: A double-edged sword
-
Kolb R, Liu GH, Janowski AM, Sutterwala FS, Zhang W. Inflammasomes in cancer: a double-edged sword. Protein Cell 2014;5:12-20.
-
(2014)
Protein Cell
, vol.5
, pp. 12-20
-
-
Kolb, R.1
Liu, G.H.2
Janowski, A.M.3
Sutterwala, F.S.4
Zhang, W.5
-
22
-
-
84886863855
-
Interleukin 18: Friend or foe in cancer
-
Palma G, Barbieri A, Bimonte S, Palla M, Zappavigna S, Caraglia M, et al. Interleukin 18: friend or foe in cancer. Biochim Biophys Acta 2013;1836:296-303.
-
(2013)
Biochim Biophys Acta
, vol.1836
, pp. 296-303
-
-
Palma, G.1
Barbieri, A.2
Bimonte, S.3
Palla, M.4
Zappavigna, S.5
Caraglia, M.6
-
23
-
-
33744539562
-
IL18 as critical co-stimulatory molecules in modulating the immune response of ITAM bearing lymphocytes
-
Ortaldo JR, Young HA. IL18 as critical co-stimulatory molecules in modulating the immune response of ITAM bearing lymphocytes. Semin Immunol 2006;18:193-6.
-
(2006)
Semin Immunol
, vol.18
, pp. 193-196
-
-
Ortaldo, J.R.1
Young, H.A.2
-
24
-
-
33750588974
-
The proinflammatory cytokine interleukin-18 alters multiple signaling pathways to inhibit natural killer cell death
-
Hodge DL, Subleski JJ, Reynolds DA, Buschman MD, Schill WB, Burkett MW, et al. The proinflammatory cytokine interleukin-18 alters multiple signaling pathways to inhibit natural killer cell death. J Interferon Cytokine Res 2006;26:706-18.
-
(2006)
J Interferon Cytokine Res
, vol.26
, pp. 706-718
-
-
Hodge, D.L.1
Subleski, J.J.2
Reynolds, D.A.3
Buschman, M.D.4
Schill, W.B.5
Burkett, M.W.6
-
25
-
-
34347371799
-
Protection of CD8+ T cells from activation-induced cell death by IL18
-
Li W, Kashiwamura S, Ueda H, Sekiyama A, Okamura H. Protection of CD8+ T cells from activation-induced cell death by IL18. J Leukoc Biol 2007;82:142-51.
-
(2007)
J Leukoc Biol
, vol.82
, pp. 142-151
-
-
Li, W.1
Kashiwamura, S.2
Ueda, H.3
Sekiyama, A.4
Okamura, H.5
-
26
-
-
77954904814
-
Effect of IL18 on expansion of gammadelta T cells stimulated by zoledronate and IL-2
-
Li W, Kubo S, Okuda A, Yamamoto H, Ueda H, Tanaka T, et al. Effect of IL18 on expansion of gammadelta T cells stimulated by zoledronate and IL-2. J Immunother 2010;33:287-96.
-
(2010)
J Immunother
, vol.33
, pp. 287-296
-
-
Li, W.1
Kubo, S.2
Okuda, A.3
Yamamoto, H.4
Ueda, H.5
Tanaka, T.6
-
27
-
-
79951823671
-
Involvement of CD56brightCD11c+ cells in IL18-mediated expansion of human γα T cells
-
Tsuda J, Li W, Yamanishi H, Yamamoto H, Okuda A, Kubo S, et al. Involvement of CD56brightCD11c+ cells in IL18-mediated expansion of human γα T cells. J Immunol 2011;186:2003-12.
-
(2011)
J Immunol
, vol.186
, pp. 2003-2012
-
-
Tsuda, J.1
Li, W.2
Yamanishi, H.3
Yamamoto, H.4
Okuda, A.5
Kubo, S.6
-
28
-
-
84892168819
-
Revisiting the Prominent Anti-Tumoral Potential of Pre-mNK Cells
-
Guimont-Desrochers F, Lesage S. Revisiting the Prominent Anti-Tumoral Potential of Pre-mNK Cells. Front Immunol 2013;4:446.
-
(2013)
Front Immunol
, vol.4
, pp. 446
-
-
Guimont-Desrochers, F.1
Lesage, S.2
-
29
-
-
84860907999
-
IKDCs or B220+ NK cells are pre-mNK cells
-
Zitvogel L, Housseau F. IKDCs or B220+ NK cells are pre-mNK cells. Blood 2012;119:4345-6.
-
(2012)
Blood
, vol.119
, pp. 4345-4346
-
-
Zitvogel, L.1
Housseau, F.2
-
30
-
-
84866789451
-
Current status and future directions in gastric cancer with peritoneal dissemination
-
Glockzin G, Piso P. Current status and future directions in gastric cancer with peritoneal dissemination. Surg Oncol Clin N Am 2012;21:625-33.
-
(2012)
Surg Oncol Clin N Am
, vol.21
, pp. 625-633
-
-
Glockzin, G.1
Piso, P.2
-
31
-
-
79952257330
-
Immunotherapy of peritoneal carcinomatosis with the antibody catumaxomab in colom, gastric, or pancreatic cancer: An open-label, multicenter, phase I/II trial
-
Ströhlein MA, Lordick F, Rüttinger D, Grützner KU, Schemanski OC, Jäger M, et al. Immunotherapy of peritoneal carcinomatosis with the antibody catumaxomab in colom, gastric, or pancreatic cancer: an open-label, multicenter, phase I/II trial. Onkologie 2011;34:101-8.
-
(2011)
Onkologie
, vol.34
, pp. 101-108
-
-
Ströhlein, M.A.1
Lordick, F.2
Rüttinger, D.3
Grützner, K.U.4
Schemanski, O.C.5
Jäger, M.6
-
32
-
-
84861533973
-
The bisphosphonate incadronate inhibits intraperitoneal dissemination in an in vivo pancreatic cancer model
-
Takiguchi S, Nishino Y, Inoue K, Ikeda M, Kataoka Y, Matsusue K, et al. The bisphosphonate incadronate inhibits intraperitoneal dissemination in an in vivo pancreatic cancer model. Oncol Rep 2012;28:111-6.
-
(2012)
Oncol Rep
, vol.28
, pp. 111-116
-
-
Takiguchi, S.1
Nishino, Y.2
Inoue, K.3
Ikeda, M.4
Kataoka, Y.5
Matsusue, K.6
-
33
-
-
39649119300
-
Efficient peritoneal dissemination treatment obtained by an immunostimulatory phosphorothioate-type CpG DNA/cationic liposome complex in mice
-
Kuramoto Y, Kawakami S, Zhou S, Fukuda K, Yamashita F, Hashida M. Efficient peritoneal dissemination treatment obtained by an immunostimulatory phosphorothioate-type CpG DNA/cationic liposome complex in mice. J Control Release 2008;126:274-80.
-
(2008)
J Control Release
, vol.126
, pp. 274-280
-
-
Kuramoto, Y.1
Kawakami, S.2
Zhou, S.3
Fukuda, K.4
Yamashita, F.5
Hashida, M.6
-
34
-
-
84975168167
-
Cancer neoantigens and applications for immunotherapy
-
Oct 29 [Epub ahead of print]
-
Desrichard A, Snyder A, Chan TA. Cancer neoantigens and applications for immunotherapy. Clin Cancer Res. 2015Oct 29 [Epub ahead of print].
-
(2015)
Clin Cancer Res
-
-
Desrichard, A.1
Snyder, A.2
Chan, T.A.3
-
35
-
-
70049104738
-
IL18 and IL-33 elicit Th2 cytokines from basophils via a MyD88- and p38alpha-dependent pathway
-
Kroeger KM, Sullivan BM, Locksley RM. IL18 and IL-33 elicit Th2 cytokines from basophils via a MyD88- and p38alpha-dependent pathway. J Leukoc Biol 2009;86:769-78.
-
(2009)
J Leukoc Biol
, vol.86
, pp. 769-778
-
-
Kroeger, K.M.1
Sullivan, B.M.2
Locksley, R.M.3
-
36
-
-
22544460544
-
The pro-atherogenic cytokine interleukin-18 induces CXCL16 expression in rat aortic smooth muscle cells via MyD88, interleukin-1 receptor-associated kinase, tumor necrosis factor receptor-associated factor 6, c-Src, phosphatidylinositol 3-kinase, Akt, c-Jun N-terminal kinase, and activator protein-1 signaling
-
Chandrasekar B, Mummidi S, Valente AJ, Patel DN, Bailey SR, Freeman GL, et al. The pro-atherogenic cytokine interleukin-18 induces CXCL16 expression in rat aortic smooth muscle cells via MyD88, interleukin-1 receptor-associated kinase, tumor necrosis factor receptor-associated factor 6, c-Src, phosphatidylinositol 3-kinase, Akt, c-Jun N-terminal kinase, and activator protein-1 signaling. J Biol Chem 2005;280:26263-77.
-
(2005)
J Biol Chem
, vol.280
, pp. 26263-26277
-
-
Chandrasekar, B.1
Mummidi, S.2
Valente, A.J.3
Patel, D.N.4
Bailey, S.R.5
Freeman, G.L.6
-
37
-
-
42949096486
-
Interleukin-18 stimulates fibronectin expression in primary human cardiac fibroblasts via PI3K-Akt-dependent NF-kappaB activation
-
Reddy VS, Harskamp RE, van Ginkel MW, Calhoon J, Baisden CE, Kim IS, et al. Interleukin-18 stimulates fibronectin expression in primary human cardiac fibroblasts via PI3K-Akt-dependent NF-kappaB activation. J Cell Physiol 2008;215:697-707.
-
(2008)
J Cell Physiol
, vol.215
, pp. 697-707
-
-
Reddy, V.S.1
Harskamp, R.E.2
Van Ginkel, M.W.3
Calhoon, J.4
Baisden, C.E.5
Kim, I.S.6
-
40
-
-
84861888837
-
Cancer-induced immunosuppression: IL18-elicited immunoablative NK cells
-
Terme M, Ullrich E, Aymeric L, Meinhardt K, Coudert JD, Desbois M, et al. Cancer-induced immunosuppression: IL18-elicited immunoablative NK cells. Cancer Res 2012;72:2757-67.
-
(2012)
Cancer Res
, vol.72
, pp. 2757-2767
-
-
Terme, M.1
Ullrich, E.2
Aymeric, L.3
Meinhardt, K.4
Coudert, J.D.5
Desbois, M.6
-
41
-
-
80051698136
-
IL18 Induces PD-1-dependent immunosuppression in cancer
-
Terme M, Ullrich E, Aymeric L, Meinhardt K, Desbois M, Delahaye N, et al. IL18 Induces PD-1-dependent immunosuppression in cancer. Cancer Res 2011;71:5393-9.
-
(2011)
Cancer Res
, vol.71
, pp. 5393-5399
-
-
Terme, M.1
Ullrich, E.2
Aymeric, L.3
Meinhardt, K.4
Desbois, M.5
Delahaye, N.6
-
42
-
-
84929167350
-
Context-dependent role of IL18 in cancer biology and counter-regulation by IL18BP
-
Fabbi M, Carbotti G, Ferrini S. Context-dependent role of IL18 in cancer biology and counter-regulation by IL18BP. J Leukoc Biol 2015;97:665-75.
-
(2015)
J Leukoc Biol
, vol.97
, pp. 665-675
-
-
Fabbi, M.1
Carbotti, G.2
Ferrini, S.3
|