Effect of IL-18 on expansion of γδ T cells stimulated by Zoledronate and IL-2

Journal of Immunotherapy

Volumn 33, Issue 3, 2010, Pages 287-296

  Li, Wen ^a,b   Kubo, Shuji ^a   Okuda, Akico ^a   Yamamoto, Hideyuki ^a   Ueda, Haruyasu ^b   Tanaka, Toshiyuki ^b   Nakamura, Hideji ^b   Yamanishi, Hiromichi ^b   Terada, Nobuyuki ^c   Okamura, Haruki ^a  

^a Institute for Advanced Medical Sciences   (Japan)

^b HYOGO COLLEGE OF MEDICINE   (Japan)

^c Hirakataryoikuen   (Japan)

Author keywords

T cell; Aicd (activation induced cell death); Antiapoptotic signals; Cellular immunotherapy; IL 18

Indexed keywords

CD27 ANTIGEN; CD44V ANTIGEN; CD45RA ANTIGEN; CD94 ANTIGEN; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 18; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR BETA; NATURAL KILLER CELL RECEPTOR NKG2D; PERFORIN; TUMOR NECROSIS FACTOR ALPHA; ZOLEDRONIC ACID;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CANCER INHIBITION; CD25+ T LYMPHOCYTE; CELL EXPANSION; CELL STIMULATION; CYTOTOXICITY; DRUG MECHANISM; GAMMA DELTA T CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MEMORY T LYMPHOCYTE; MESOTHELIOMA; MOUSE; NONHUMAN; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIBODIES; BONE DENSITY CONSERVATION AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CYTOKINES; DIPHOSPHONATES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HEP G2 CELLS; HUMANS; IMIDAZOLES; IMMUNOPHENOTYPING; INTERLEUKIN-18; INTERLEUKIN-2; LEUKOCYTES, MONONUCLEAR; MESOTHELIOMA; MICE; MICE, INBRED NOD; MICE, SCID; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; RECEPTORS, INTERLEUKIN-18; T-LYMPHOCYTES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 77954904814     PISSN: 15249557     EISSN: None     Source Type: Journal    
DOI: 10.1097/CJI.0b013e3181c80ffa     Document Type: Article

References (40)

1. Kronenberg M, Havran WL. Frontline T cells: gammadelta T cells and intraepithelial lymphocytes. Immunol Rev. 2007;215:5-7.
2. Beetz S, Wesch D, Marischen L, et al. Innate immune functions of human gammadelta T cells. Immunobiology. 2008;213:173-182.
3. Moser B, Eberl M. Gammdelta T cells: novel initiators of adaptive immunity. Immunol Rev. 2007;215:89-102.
4. Scotet E, Nedellec S, Devilder MC, et al. Bridging innate and adaptive immunity through gammadelta T-dendritic cell crosstalk. Front Biosci. 2008;13:6872-6885.
5. Thedrez A, Sabourin C, Gertner J, et al. Self/non-self discrimination by human gd T cells: simple solutions for a complex issue? Immunol Rev. 2007;215:123-135.
6. Chien YH, Konigshofer Y. Antigen recognition by gammadelta T cells. Immunol Rev. 2007;215:46-58.
7. Caccamo N, Meraviglia S, Cicero G, et al. Aminobisphosphonates as new weapons for gammadelta T cell-based immunotherapy of cancer. Curr Med Chem. 2008;15:1147-1153.
8. Tanaka Y. Human gdT cells and tumor immunotherapy. J Clin Exp Hematopathol. 2006;46:11-23.
9. O'Brien RL, Roark CL, Jin N, et al. Gammmadelta T-cell receptors: functional correlation. Immunol Rev. 2007;215:77-88.
10. Dieli F, Poccia F, Lipp M, et al. Differentiation of effector/memory Vd2 T cells and migratory routes in lymph nodes or inflammatory sites. J Exp Med. 2003;198:391-397.
11. De Rosa SC, Andrus SC, Perfetto JP, et al. Ontogeny of gd T cells in humans. J Immunol. 2004;172:1637-1645.
12. Eberl M, Engel R, Aberle S, et al. Human Vg9/Vd2 effector memory T cells express the killer cell lectin-like receptor G1 (KLRG1). J Leukoc Biol. 2005;77:67-70.
13. Martino A, Casetti R, Sacchi A, et al. Central memory Vg9Vd2 T lymphocytes primed and expanded by Bacillus Calmette-Guerin-infected dendritic cells kill Mycobacterial-infected monocytes. J Immunol. 2007;179:3057-3064.
14. Pitard V, Roumanes D, Lafarge X, et al. Long-term expansion of effector/memory Vd2-gd T cells is a specific blood signature of CMV infection. Blood. 2008;112:1317-1324.
15. Joshi NS, Kaech SM. Effector CD8 T cell development: a balancing act between memory cell potential and terminal differentiation. J Immunol. 2008;180:1309-1315.
16. Harty JT, Badovinac VP. Shaping and reshaping CD8+ T-cell memory. Nature Rev/Immunol. 2008;8:107-119.
17. Iwai Y, Hemmi H, Mizenina O, et al. An IFN-g-IL-18 signaling loop accelerates memory CD8+ T cell proliferation. PloS ONE. 2008;3: E2404.
18. Tough DF, Zhang X, Sprent J. An IFN-g-Dependent pathway controls stimulation of memory phenotype CD8+ T cells turnover in vivo by IL-12, IL-18, and IFN-g. J Immunol. 2001;166:6007-6011.
19. Okamura H, Tsutsui H, Komatsu T, et al. Cloning of a new cytokine that induces IFN-gamma production by T cells. Nature. 1995;378:88-91.
20. Nakanishi K, Yoshimoto T, Tsutsui H, et al. Interleukin-18 regulates both Th1 and Th2 responses. Annu Rev Immunol. 2001;19:423-474.
21. Ortaldo JR, Young HA. IL-18 as critical co-stimulatory molecules in modulating the immune response of ITAM bearing lymphocytes. Semin Immunol. 2006;18:193-196.
22. Dinarello CA. Interleukin-18 and the pathogenesis of inflammatory diseases. Semin Nephrol. 2007;27:98-114.
23. Takeuchi M, Okura T, Mori T, et al. Intracellular production of interleukin-18 in human epithelial-like cell lines is enhanced by hypersomotic stress in vitro. Cell Tissue Res. 1999;297:467-473.
24. Cho D, Kang SJ, Park HJ, et al. The enhanced IL-18 production by UVB irradiation requires ROI and AP-1 signaling in human keratinocyte cell lines (HaCaT). Biochem Biophys Res Commun. 2002;298:289-295.
25. Chandrasekar B, Colston JT, de la Rosa SD, et al. TNF-alpha and H2O2 induce IL-18 and IL-18R beta expression in cardiomyocytes via NF-kappa B activation. Biochem Biophys Res Commun. 2003;303:1152-1158.
26. Chandrasekar B, Mummidi S, Claycomb WC, et al. IL-18 is a pro-hypertrophic cytokine that acts through a phosphatidylinositol 3-Kinase-Phosphoinostide-dependent Kinase-1-Akt-GATA4 signaling pathway in cardiomyocytes. J Biol Chem. 2005;280:4553-4567.
27. Hodge DL, Subleski JJ, Reynolds DA, et al. The proinflamamatory cytokine interleukin-18 alters multiple signaling pathways to inhibit natural killer cell death. J Interferon Cytokine Res. 2006;26:706-718.
28. Li W, Kashiwamura S, Ueda H, et al. Protection of CD8+ T cells from activation-induced cell death by IL-18. J Leukoc Biol. 2007;82:142-151.
29. Claudio E, Brown K, Siebenlist U. NF-kB guides the survival and differentiation of developing lymphocytes. Cell Death Differentiation. 2006;13:697-701.
30. Piva R, Belardo G, Santoro MG. NF-kappaB: a stressregulated switch for cell survival. Antioxid Redox Signal. 2006;8:478-486.
31. Majumdar G, Johnson IM, Kale S, et al. Epigenetic regulation of cardiac muscle-specific genes in H9c2 cells by interleukin-18 and histone deacetylase inhibitor m-carboxycinnamic acid bishydroxamide. Mol Cell Biochem. 2008;312:47-60.
32. Hirata J, Kotani J, Aoyama M, et al. A role for IL-18 in human neutrophil apoptosis. Shock. 2008;30:628-633.
33. Hosotani Y, Kashiwamura S, Kimura-Shimmyou A, et al. Interleukin-18 prevents apoptosis via PI3K/Akt pathway in normal human keratinocytes. J Dermatol. 2008;35:514-524.
34. Colonna-Romano G, Potestio M, Aquino A, et al. Gammadelta T lymphocytes are affected in the elderly. Exp Gerontol. 2002;37:205-211.
35. Smeltz RB. Pronounced enhancement of the IL-12/IL-18 pathway of IFN-gamma secretion in human CD8+ memory T cell subsets via IL-15. J Immunol. 2007;178:4786-4792.
36. Kambayashi T, Assarsson E, Lukacher AE, et al. Memory CD8+ T cells provide an early source of IFN-gamma. J Immunol. 2003;170:2399-2408.
37. Luo Y, Zhou H, Mizutani N, et al. A DNA vaccine targeting Fos-related antigen 1 enhanced by IL-18 induces long-lived T cell memory against tumor recurrence. Caancer Res. 2005;65:3419-3427.
38. Waldmann TA. The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design. Nat Rev Immunol. 2006;6:595-601.
39. Smyth MJ, Swann J, Cretney E, et al. Yokoyama, Yoshihiro Hayakawa. NKG2D function protects the host from tumor initiation. The J Exp Med. 2005;5:583-588.
40. Jamieson AM, Diefenbach A, McMahon CW, et al. The role of the NKG2D immunorector in immune cell activation and natural killing. Immunity. 2002;17:19-29.