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Volumn 196, Issue 10, 2016, Pages 4172-4184

Whole-virion influenza vaccine recalls an early burst of high-affinity memory B cell response through TLR signaling

Author keywords

[No Author keywords available]

Indexed keywords

INFLUENZA VACCINE; NEUTRALIZING ANTIBODY; SPLIT VIRION INFLUENZA VACCINE; TOLL LIKE RECEPTOR 7; UNCLASSIFIED DRUG; VIRUS RNA; WHOLE VIRION INFLUENZA VACCINE; MEMBRANE PROTEIN; TLR7 PROTEIN, MOUSE; VIRUS ANTIBODY;

EID: 84975048599     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1600046     Document Type: Article
Times cited : (35)

References (84)
  • 1
    • 0030001674 scopus 로고    scopus 로고
    • Immunological memory and protective immunity: Understanding their relation
    • Ahmed, R., and D. Gray. 1996. Immunological memory and protective immunity: understanding their relation. Science 272: 54-60.
    • (1996) Science , vol.272 , pp. 54-60
    • Ahmed, R.1    Gray, D.2
  • 2
    • 77954357410 scopus 로고    scopus 로고
    • Correlates of protection induced by vaccination
    • Plotkin, S. A. 2010. Correlates of protection induced by vaccination. Clin. Vaccine Immunol. 17: 1055-1065.
    • (2010) Clin. Vaccine Immunol. , vol.17 , pp. 1055-1065
    • Plotkin, S.A.1
  • 5
    • 0017336892 scopus 로고
    • Influenza vaccine: Split-product versus whole-virus types-How do they differ
    • Gross, P. A., and F. A. Ennis. 1977. Influenza vaccine: split-product versus whole-virus types-How do they differ. N. Engl. J. Med. 296: 567-568.
    • (1977) N. Engl. J. Med. , vol.296 , pp. 567-568
    • Gross, P.A.1    Ennis, F.A.2
  • 6
    • 0017669707 scopus 로고
    • A controlled double-blind comparison of reactogenicity, immunogenicity, and protective efficacy of whole-virus and split-product influenza vaccines in children
    • Gross, P. A., F. A. Ennis, P. F. Gaerlan, L. J. Denson, C. R. Denning, and D. Schiffman. 1977. A controlled double-blind comparison of reactogenicity, immunogenicity, and protective efficacy of whole-virus and split-product influenza vaccines in children. J. Infect. Dis. 136: 623-632.
    • (1977) J. Infect. Dis. , vol.136 , pp. 623-632
    • Gross, P.A.1    Ennis, F.A.2    Gaerlan, P.F.3    Denson, L.J.4    Denning, C.R.5    Schiffman, D.6
  • 7
    • 0031930630 scopus 로고    scopus 로고
    • Comparison of serology and reactogenicity between influenza subunit vaccines and whole virus or split vaccines: A review and meta-analysis of the literature
    • Beyer, W. E., A. M. Palache, and A. D. Osterhaus. 1998. Comparison of Serology and Reactogenicity between Influenza Subunit Vaccines and Whole Virus or Split Vaccines: A Review and Meta-Analysis of the Literature. Clin. Drug Investig. 15: 1-12.
    • (1998) Clin. Drug Investig. , vol.15 , pp. 1-12
    • Beyer, W.E.1    Palache, A.M.2    Osterhaus, A.D.3
  • 8
    • 1542317550 scopus 로고    scopus 로고
    • Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
    • Diebold, S. S., T. Kaisho, H. Hemmi, S. Akira, and C. Reis e Sousa. 2004. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 303: 1529-1531.
    • (2004) Science , vol.303 , pp. 1529-1531
    • Diebold, S.S.1    Kaisho, T.2    Hemmi, H.3    Akira, S.4    Reis-Sousa, C.5
  • 10
    • 41149150143 scopus 로고    scopus 로고
    • Toll-like receptor expression and responsiveness of distinct murine splenic and mucosal B-cell subsets
    • Gururajan, M., J. Jacob, and B. Pulendran. 2007. Toll-like receptor expression and responsiveness of distinct murine splenic and mucosal B-cell subsets. PLoS One 2: e863.
    • (2007) PLoS One , vol.2 , pp. e863
    • Gururajan, M.1    Jacob, J.2    Pulendran, B.3
  • 11
    • 0036570169 scopus 로고    scopus 로고
    • Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides
    • Hornung, V., S. Rothenfusser, S. Britsch, A. Krug, B. Jahrsdörfer, T. Giese, S. Endres, and G. Hartmann. 2002. Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J. Immunol. 168: 4531-4537.
    • (2002) J. Immunol. , vol.168 , pp. 4531-4537
    • Hornung, V.1    Rothenfusser, S.2    Britsch, S.3    Krug, A.4    Jahrsdörfer, B.5    Giese, T.6    Endres, S.7    Hartmann, G.8
  • 12
    • 27844541797 scopus 로고    scopus 로고
    • Control of B-cell responses by Toll-like receptors
    • Pasare, C., and R. Medzhitov. 2005. Control of B-cell responses by Toll-like receptors. Nature 438: 364-368.
    • (2005) Nature , vol.438 , pp. 364-368
    • Pasare, C.1    Medzhitov, R.2
  • 13
    • 33845905223 scopus 로고    scopus 로고
    • Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling
    • Gavin, A. L., K. Hoebe, B. Duong, T. Ota, C. Martin, B. Beutler, and D. Nemazee. 2006. Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling. Science 314: 1936-1938.
    • (2006) Science , vol.314 , pp. 1936-1938
    • Gavin, A.L.1    Hoebe, K.2    Duong, B.3    Ota, T.4    Martin, C.5    Beutler, B.6    Nemazee, D.7
  • 14
    • 37549034962 scopus 로고    scopus 로고
    • B cell intrinsic TLR signals amplify but are not required for humoral immunity
    • Meyer-Bahlburg, A., S. Khim, and D. J. Rawlings. 2007. B cell intrinsic TLR signals amplify but are not required for humoral immunity. J. Exp. Med. 204: 3095-3101.
    • (2007) J. Exp. Med. , vol.204 , pp. 3095-3101
    • Meyer-Bahlburg, A.1    Khim, S.2    Rawlings, D.J.3
  • 16
    • 79952745936 scopus 로고    scopus 로고
    • Selective utilization of Toll-like receptor and MyD88 signaling in B cells for enhancement of the antiviral germinal center response
    • Hou, B., P. Saudan, G. Ott, M. L. Wheeler, M. Ji, L. Kuzmich, L. M. Lee, R. L. Coffman, M. F. Bachmann, and A. L. DeFranco. 2011. Selective utilization of Toll-like receptor and MyD88 signaling in B cells for enhancement of the antiviral germinal center response. Immunity 34: 375-384.
    • (2011) Immunity , vol.34 , pp. 375-384
    • Hou, B.1    Saudan, P.2    Ott, G.3    Wheeler, M.L.4    Ji, M.5    Kuzmich, L.6    Lee, L.M.7    Coffman, R.L.8    Bachmann, M.F.9    DeFranco, A.L.10
  • 18
    • 80055080756 scopus 로고    scopus 로고
    • Toll-like receptor 7 controls the anti-retroviral germinal center response
    • Browne, E. P. 2011. Toll-like receptor 7 controls the anti-retroviral germinal center response. PLoS Pathog. 7: e1002293.
    • (2011) PLoS Pathog. , vol.7 , pp. e1002293
    • Browne, E.P.1
  • 19
    • 84880087672 scopus 로고    scopus 로고
    • B cell-intrinsic TLR7 signaling is required for optimal B cell responses during chronic viral infection
    • Clingan, J. M., and M. Matloubian. 2013. B cell-intrinsic TLR7 signaling is required for optimal B cell responses during chronic viral infection. J. Immunol. 191: 810-818.
    • (2013) J. Immunol. , vol.191 , pp. 810-818
    • Clingan, J.M.1    Matloubian, M.2
  • 20
    • 67650679858 scopus 로고    scopus 로고
    • Protective immunity afforded by inactivated H5N1 (NIBRG-14) vaccine requires antibodies against both hemagglutinin and neuraminidase in mice
    • Takahashi, Y., H. Hasegawa, Y. Hara, M. Ato, A. Ninomiya, H. Takagi, T. Odagiri, T. Sata, M. Tashiro, and K. Kobayashi. 2009. Protective immunity afforded by inactivated H5N1 (NIBRG-14) vaccine requires antibodies against both hemagglutinin and neuraminidase in mice. J. Infect. Dis. 199: 1629-1637.
    • (2009) J. Infect. Dis. , vol.199 , pp. 1629-1637
    • Takahashi, Y.1    Hasegawa, H.2    Hara, Y.3    Ato, M.4    Ninomiya, A.5    Takagi, H.6    Odagiri, T.7    Sata, T.8    Tashiro, M.9    Kobayashi, K.10
  • 25
    • 0032525003 scopus 로고    scopus 로고
    • Kinetics of establishing the memory B cell population as revealed by CD38 expression
    • Ridderstad, A., and D. M. Tarlinton. 1998. Kinetics of establishing the memory B cell population as revealed by CD38 expression. J. Immunol. 160: 4688-4695.
    • (1998) J. Immunol. , vol.160 , pp. 4688-4695
    • Ridderstad, A.1    Tarlinton, D.M.2
  • 26
    • 0035099037 scopus 로고    scopus 로고
    • Fas is required for clonal selection in germinal centers and the subsequent establishment of the memory B cell repertoire
    • Takahashi, Y., H. Ohta, and T. Takemori. 2001. Fas is required for clonal selection in germinal centers and the subsequent establishment of the memory B cell repertoire. Immunity 14: 181-192.
    • (2001) Immunity , vol.14 , pp. 181-192
    • Takahashi, Y.1    Ohta, H.2    Takemori, T.3
  • 27
    • 70349750487 scopus 로고    scopus 로고
    • Cloning and expression of murine Ig genes from single B cells
    • Tiller, T., C. E. Busse, and H. Wardemann. 2009. Cloning and expression of murine Ig genes from single B cells. J. Immunol. Methods 350: 183-193.
    • (2009) J. Immunol. Methods , vol.350 , pp. 183-193
    • Tiller, T.1    Busse, C.E.2    Wardemann, H.3
  • 28
    • 0037529321 scopus 로고    scopus 로고
    • Unmutated immunoglobulin M can protect mice from death by influenza virus infection
    • Harada, Y., M. Muramatsu, T. Shibata, T. Honjo, and K. Kuroda. 2003. Unmutated immunoglobulin M can protect mice from death by influenza virus infection. J. Exp. Med. 197: 1779-1785.
    • (2003) J. Exp. Med. , vol.197 , pp. 1779-1785
    • Harada, Y.1    Muramatsu, M.2    Shibata, T.3    Honjo, T.4    Kuroda, K.5
  • 32
    • 0033919320 scopus 로고    scopus 로고
    • B-cell subsets and the mature preimmune repertoire. Marginal zone and B1 B cells as part of a "natural immune memory"
    • Martin, F., and J. F. Kearney. 2000. B-cell subsets and the mature preimmune repertoire. Marginal zone and B1 B cells as part of a "natural immune memory". Immunol. Rev. 175: 70-79.
    • (2000) Immunol. Rev. , vol.175 , pp. 70-79
    • Martin, F.1    Kearney, J.F.2
  • 33
    • 0029608873 scopus 로고
    • T helper cellindependent neutralizing B cell response against vesicular stomatitis virus: Role of antigen patterns in B cell induction?
    • Bachmann, M. F., H. Hengartner, and R. M. Zinkernagel. 1995. T helper cellindependent neutralizing B cell response against vesicular stomatitis virus: role of antigen patterns in B cell induction? Eur. J. Immunol. 25: 3445-3451.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 3445-3451
    • Bachmann, M.F.1    Hengartner, H.2    Zinkernagel, R.M.3
  • 36
    • 0034700081 scopus 로고    scopus 로고
    • Protective long-term antibody memory by antigendriven and T help-dependent differentiation of long-lived memory B cells to short-lived plasma cells independent of secondary lymphoid organs
    • Ochsenbein, A. F., D. D. Pinschewer, S. Sierro, E. Horvath, H. Hengartner, and R. M. Zinkernagel. 2000. Protective long-term antibody memory by antigendriven and T help-dependent differentiation of long-lived memory B cells to short-lived plasma cells independent of secondary lymphoid organs. Proc. Natl. Acad. Sci. USA 97: 13263-13268.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 13263-13268
    • Ochsenbein, A.F.1    Pinschewer, D.D.2    Sierro, S.3    Horvath, E.4    Hengartner, H.5    Zinkernagel, R.M.6
  • 37
    • 38949117752 scopus 로고    scopus 로고
    • Differential role of TLR-and RLR-signaling in the immune responses to influenza Avirus infection and vaccination
    • Koyama, S., K. J. Ishii, H. Kumar, T. Tanimoto, C. Coban, S. Uematsu, T. Kawai, and S. Akira. 2007. Differential role of TLR-and RLR-signaling in the immune responses to influenza Avirus infection and vaccination. J. Immunol. 179: 4711-4720.
    • (2007) J. Immunol. , vol.179 , pp. 4711-4720
    • Koyama, S.1    Ishii, K.J.2    Kumar, H.3    Tanimoto, T.4    Coban, C.5    Uematsu, S.6    Kawai, T.7    Akira, S.8
  • 38
    • 33846937311 scopus 로고    scopus 로고
    • TLR signaling fine-tunes anti-influenza B cell responses without regulating effector T cell responses
    • Heer, A. K., A. Shamshiev, A. Donda, S. Uematsu, S. Akira, M. Kopf, and B. J. Marsland. 2007. TLR signaling fine-tunes anti-influenza B cell responses without regulating effector T cell responses. J. Immunol. 178: 2182-2191.
    • (2007) J. Immunol. , vol.178 , pp. 2182-2191
    • Heer, A.K.1    Shamshiev, A.2    Donda, A.3    Uematsu, S.4    Akira, S.5    Kopf, M.6    Marsland, B.J.7
  • 39
    • 84871933837 scopus 로고    scopus 로고
    • Disparate adjuvant properties among three formulations of "alum"
    • Cain, D. W., S. E. Sanders, M. M. Cunningham, and G. Kelsoe. 2013. Disparate adjuvant properties among three formulations of "alum". Vaccine 31: 653-660.
    • (2013) Vaccine , vol.31 , pp. 653-660
    • Cain, D.W.1    Sanders, S.E.2    Cunningham, M.M.3    Kelsoe, G.4
  • 40
    • 45749111446 scopus 로고    scopus 로고
    • Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
    • Eisenbarth, S. C., O. R. Colegio, W. O'Connor, F. S. Sutterwala, and R. A. Flavell. 2008. Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants. Nature 453: 1122-1126.
    • (2008) Nature , vol.453 , pp. 1122-1126
    • Eisenbarth, S.C.1    Colegio, O.R.2    O'Connor, W.3    Sutterwala, F.S.4    Flavell, R.A.5
  • 41
    • 2942701975 scopus 로고    scopus 로고
    • Promotion of B cell immune responses via an alum-induced myeloid cell population
    • Jordan, M. B., D. M. Mills, J. Kappler, P. Marrack, and J. C. Cambier. 2004. Promotion of B cell immune responses via an alum-induced myeloid cell population. Science 304: 1808-1810.
    • (2004) Science , vol.304 , pp. 1808-1810
    • Jordan, M.B.1    Mills, D.M.2    Kappler, J.3    Marrack, P.4    Cambier, J.C.5
  • 44
    • 47849087075 scopus 로고    scopus 로고
    • Cutting edge: Inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3
    • Li, H., S. B. Willingham, J. P. Ting, and F. Re. 2008. Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3. J. Immunol. 181: 17-21.
    • (2008) J. Immunol. , vol.181 , pp. 17-21
    • Li, H.1    Willingham, S.B.2    Ting, J.P.3    Re, F.4
  • 46
    • 77955921430 scopus 로고    scopus 로고
    • The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88
    • He, B., R. Santamaria, W. Xu, M. Cols, K. Chen, I. Puga, M. Shan, H. Xiong, J. B. Bussel, A. Chiu, et al. 2010. The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88. Nat. Immunol. 11: 836-845.
    • (2010) Nat. Immunol. , vol.11 , pp. 836-845
    • He, B.1    Santamaria, R.2    Xu, W.3    Cols, M.4    Chen, K.5    Puga, I.6    Shan, M.7    Xiong, H.8    Bussel, J.B.9    Chiu, A.10
  • 47
    • 34247566510 scopus 로고    scopus 로고
    • The family of five: TIR-domaincontaining adaptors in Toll-like receptor signalling
    • O'Neill, L. A., and A. G. Bowie. 2007. The family of five: TIR-domaincontaining adaptors in Toll-like receptor signalling. Nat. Rev. Immunol. 7: 353-364.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 353-364
    • O'Neill, L.A.1    Bowie, A.G.2
  • 49
    • 78650647005 scopus 로고    scopus 로고
    • Cutting edge: Hierarchy of maturity of murine memory B cell subsets
    • Tomayko, M. M., N. C. Steinel, S. M. Anderson, and M. J. Shlomchik. 2010. Cutting edge: Hierarchy of maturity of murine memory B cell subsets. J. Immunol. 185: 7146-7150.
    • (2010) J. Immunol. , vol.185 , pp. 7146-7150
    • Tomayko, M.M.1    Steinel, N.C.2    Anderson, S.M.3    Shlomchik, M.J.4
  • 50
    • 1442302892 scopus 로고    scopus 로고
    • Inactivated influenza virus vaccines in children
    • Ruben, F. L. 2004. Inactivated influenza virus vaccines in children. Clin. Infect. Dis. 38: 678-688.
    • (2004) Clin. Infect. Dis. , vol.38 , pp. 678-688
    • Ruben, F.L.1
  • 53
  • 54
    • 0035013708 scopus 로고    scopus 로고
    • Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens
    • Martin, F., A. M. Oliver, and J. F. Kearney. 2001. Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens. Immunity 14: 617-629.
    • (2001) Immunity , vol.14 , pp. 617-629
    • Martin, F.1    Oliver, A.M.2    Kearney, J.F.3
  • 55
    • 0036380003 scopus 로고    scopus 로고
    • The dual function of the splenic marginal zone: Essential for initiation of anti-TI-2 responses but also vital in the general first-line defense against blood-borne antigens
    • Zandvoort, A., and W. Timens. 2002. The dual function of the splenic marginal zone: essential for initiation of anti-TI-2 responses but also vital in the general first-line defense against blood-borne antigens. Clin. Exp. Immunol. 130: 4-11.
    • (2002) Clin. Exp. Immunol. , vol.130 , pp. 4-11
    • Zandvoort, A.1    Timens, W.2
  • 56
    • 18844398045 scopus 로고    scopus 로고
    • Marginal zone B cells in lymphocyte activation and regulation
    • Lopes-Carvalho, T., J. Foote, and J. F. Kearney. 2005. Marginal zone B cells in lymphocyte activation and regulation. Curr. Opin. Immunol. 17: 244-250.
    • (2005) Curr. Opin. Immunol. , vol.17 , pp. 244-250
    • Lopes-Carvalho, T.1    Foote, J.2    Kearney, J.F.3
  • 57
    • 0042689324 scopus 로고
    • Molecular determinants of immunogenicity: The immunon model of immune response
    • Dintzis, H. M., R. Z. Dintzis, and B. Vogelstein. 1976. Molecular determinants of immunogenicity: the immunon model of immune response. Proc. Natl. Acad. Sci. USA 73: 3671-3675.
    • (1976) Proc. Natl. Acad. Sci. USA , vol.73 , pp. 3671-3675
    • Dintzis, H.M.1    Dintzis, R.Z.2    Vogelstein, B.3
  • 58
    • 0024395440 scopus 로고
    • The immunogenicity of soluble haptenated polymers is determined by molecular mass and hapten valence
    • Dintzis, R. Z., M. Okajima, M. H. Middleton, G. Greene, and H. M. Dintzis. 1989. The immunogenicity of soluble haptenated polymers is determined by molecular mass and hapten valence. J. Immunol. 143: 1239-1244.
    • (1989) J. Immunol. , vol.143 , pp. 1239-1244
    • Dintzis, R.Z.1    Okajima, M.2    Middleton, M.H.3    Greene, G.4    Dintzis, H.M.5
  • 61
    • 0038142387 scopus 로고    scopus 로고
    • A role for Toll-like receptors in acquired immunity: Up-regulation of TLR9 by BCR triggering in naive B cells and constitutive expression in memory B cells
    • Bernasconi, N. L., N. Onai, and A. Lanzavecchia. 2003. A role for Toll-like receptors in acquired immunity: up-regulation of TLR9 by BCR triggering in naive B cells and constitutive expression in memory B cells. Blood 101: 4500-4504.
    • (2003) Blood , vol.101 , pp. 4500-4504
    • Bernasconi, N.L.1    Onai, N.2    Lanzavecchia, A.3
  • 63
    • 0041743207 scopus 로고    scopus 로고
    • The toll-like receptor repertoire of human B lymphocytes: Inducible and selective expression of TLR9 and TLR10 in normal and transformed cells
    • Bourke, E., D. Bosisio, J. Golay, N. Polentarutti, and A. Mantovani. 2003. The toll-like receptor repertoire of human B lymphocytes: inducible and selective expression of TLR9 and TLR10 in normal and transformed cells. Blood 102: 956-963.
    • (2003) Blood , vol.102 , pp. 956-963
    • Bourke, E.1    Bosisio, D.2    Golay, J.3    Polentarutti, N.4    Mantovani, A.5
  • 65
    • 84875551472 scopus 로고    scopus 로고
    • Broadly neutralizing antiviral antibodies
    • Corti, D., and A. Lanzavecchia. 2013. Broadly neutralizing antiviral antibodies. Annu. Rev. Immunol. 31: 705-742.
    • (2013) Annu. Rev. Immunol. , vol.31 , pp. 705-742
    • Corti, D.1    Lanzavecchia, A.2
  • 66
    • 84874187612 scopus 로고    scopus 로고
    • Re-engaging cross-reactive memory B cells: The influenza puzzle
    • Ellebedy, A. H., and R. Ahmed. 2012. Re-engaging cross-reactive memory B cells: the influenza puzzle. Front. Immunol. 3: 53.
    • (2012) Front. Immunol. , vol.3 , pp. 53
    • Ellebedy, A.H.1    Ahmed, R.2
  • 69
    • 84860363209 scopus 로고    scopus 로고
    • A germinal centerindependent pathway generates unswitched memory B cells early in the primary response
    • Taylor, J. J., K. A. Pape, and M. K. Jenkins. 2012. A germinal centerindependent pathway generates unswitched memory B cells early in the primary response. J. Exp. Med. 209: 597-606.
    • (2012) J. Exp. Med. , vol.209 , pp. 597-606
    • Taylor, J.J.1    Pape, K.A.2    Jenkins, M.K.3
  • 70
    • 77955862163 scopus 로고    scopus 로고
    • In vivo control of B-cell survival and antigen-specific B-cell responses
    • Chan, T. D., S. Gardam, D. Gatto, V. M. Turner, J. Silke, and R. Brink. 2010. In vivo control of B-cell survival and antigen-specific B-cell responses. Immunol. Rev. 237: 90-103.
    • (2010) Immunol. Rev. , vol.237 , pp. 90-103
    • Chan, T.D.1    Gardam, S.2    Gatto, D.3    Turner, V.M.4    Silke, J.5    Brink, R.6
  • 71
    • 33645856486 scopus 로고    scopus 로고
    • Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation
    • Paus, D., T. G. Phan, T. D. Chan, S. Gardam, A. Basten, and R. Brink. 2006. Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation. J. Exp. Med. 203: 1081-1091.
    • (2006) J. Exp. Med. , vol.203 , pp. 1081-1091
    • Paus, D.1    Phan, T.G.2    Chan, T.D.3    Gardam, S.4    Basten, A.5    Brink, R.6
  • 74
    • 84903517553 scopus 로고    scopus 로고
    • Germinal center reaction: Antigen affinity and presentation explain it all
    • Oropallo, M. A., and A. Cerutti. 2014. Germinal center reaction: antigen affinity and presentation explain it all. Trends Immunol. 35: 287-289.
    • (2014) Trends Immunol. , vol.35 , pp. 287-289
    • Oropallo, M.A.1    Cerutti, A.2
  • 75
    • 50849107415 scopus 로고    scopus 로고
    • Whole inactivated virus influenza vaccine is superior to subunit vaccine in inducing immune responses and secretion of proinflammatory cytokines by DCs
    • Geeraedts, F., L. Bungener, J. Pool, W. ter Veer, J. Wilschut, and A. Huckriede. 2008. Whole inactivated virus influenza vaccine is superior to subunit vaccine in inducing immune responses and secretion of proinflammatory cytokines by DCs. Influenza Other Respi. Viruses 2: 41-51.
    • (2008) Influenza Other Respi. Viruses , vol.2 , pp. 41-51
    • Geeraedts, F.1    Bungener, L.2    Pool, J.3    Ter Veer, W.4    Wilschut, J.5    Huckriede, A.6
  • 77
  • 78
    • 22644447284 scopus 로고    scopus 로고
    • Whole influenza virus vaccine is more immunogenic than split influenza virus vaccine and induces primarily an IgG2a response in BALB/c mice. Scand
    • Hovden, A. O., R. J. Cox, and L. R. Haaheim. 2005. Whole influenza virus vaccine is more immunogenic than split influenza virus vaccine and induces primarily an IgG2a response in BALB/c mice. Scand. J. Immunol. 62: 36-44.
    • (2005) J. Immunol. , vol.62 , pp. 36-44
    • Hovden, A.O.1    Cox, R.J.2    Haaheim, L.R.3
  • 79
    • 0025895936 scopus 로고
    • Comparison of adverse reactions to whole-virion and split-virion influenza vaccines in hospital personnel
    • al-Mazrou, A., D.W. Scheifele, T. Soong, and G. Bjornson. 1991. Comparison of adverse reactions to whole-virion and split-virion influenza vaccines in hospital personnel. CMAJ 145: 213-218.
    • (1991) CMAJ , vol.145 , pp. 213-218
    • Al-Mazrou, A.1    Scheifele, D.W.2    Soong, T.3    Bjornson, G.4
  • 81
    • 0017605883 scopus 로고
    • Studies of inactivated influenza virus vaccines in hospital employees: Reactogenicity and absenteeism
    • Mostow, S. R., T. C. Eickhoff, G. A. Chelgren, H. F. Retailliau, and M. Castle. 1977. Studies of inactivated influenza virus vaccines in hospital employees: reactogenicity and absenteeism. J. Infect. Dis. 136(Suppl.): S533-S538.
    • (1977) J. Infect. Dis. , vol.136 , pp. S533-S538
    • Mostow, S.R.1    Eickhoff, T.C.2    Chelgren, G.A.3    Retailliau, H.F.4    Castle, M.5
  • 82
    • 0017610114 scopus 로고
    • Trials of influenza A/New Jersey/76 virus vaccine in normal children: An overview of age-related antigenicity and reactogenicity
    • Wright, P. F., J. Thompson, W. K. Vaughn, D. S. Folland, S. H. Sell, and D. T. Karzon. 1977. Trials of influenza A/New Jersey/76 virus vaccine in normal children: an overview of age-related antigenicity and reactogenicity. J. Infect. Dis. 136(Suppl.): S731-S741.
    • (1977) J. Infect. Dis. , vol.136 , pp. S731-S741
    • Wright, P.F.1    Thompson, J.2    Vaughn, W.K.3    Folland, D.S.4    Sell, S.H.5    Karzon, D.T.6
  • 83
    • 33749544393 scopus 로고    scopus 로고
    • Impact of influenza vaccine formulation with a detailed analysis of the cytokine response
    • Szyszko, E., K. Brokstad, R. J. Cox, A. O. Hovden, A. Madhun, and L. R. Haaheim. 2006. Impact of influenza vaccine formulation with a detailed analysis of the cytokine response. Scand. J. Immunol. 64: 467-475.
    • (2006) Scand J. Immunol. , vol.64 , pp. 467-475
    • Szyszko, E.1    Brokstad, K.2    Cox, R.J.3    Hovden, A.O.4    Madhun, A.5    Haaheim, L.R.6


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