Intense, passionate, romantic love: A natural addiction? How the fields that investigate romance and substance abuse can inform each other

Frontiers in Psychology

Volumn 7, Issue MAY, 2016, Pages

  Fisher, Helen E ^a   Xu, Xiaomeng ^b   Aron, Arthur ^c   Brown, Lucy L ^d  

^a INDIANA UNIVERSITY   (United States)

^b IDAHO STATE UNIVERSITY   (United States)

^c STONY BROOK UNIVERSITY   (United States)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Addiction; Caudate; Romantic love; Ventral tegmental area

Indexed keywords

EID: 84974721813     PISSN: None     EISSN: 16641078     Source Type: Journal    
DOI: 10.3389/fpsyg.2016.00687     Document Type: Review

References (120)

1. Acevedo, B., Aron, A., Fisher, H., and Brown, L. (2011). Neural correlates of long-term intense romantic love. Soc. Cogn. Affect. Neurosci. 7, 145-159. doi: 10.1093/scan/nsq092
2. Agnew, C. R., Van Lange, P. A. M., Rusbult, C. E., and Langston, C. A. (1998). Cognitive interdependence: commitment and the mental representation of close relationships. J. Pers. Soc. Psychol. 74, 939-954. doi: 10.1037/0022-3514.74.4.939
3. Ainsworth, M. D. S., Blehar, M. C., Waters, E., and Wall, S. N. (1978). Patterns of Attachment: A Psychological Study of the Strange Situation. Hillsdale, NJ: Erlbaum.
4. Alter, R. J., Lohrmann, D. K., and Greene, R. (2006). Substitution of marijuana for alcohol: the role of perceived access and harm. J. Drug. Educ. 26, 335-355. doi: 10.2190/2780-G96W-J17N-R3H1
5. American Psychiatric Association (2013). Diagnostic and Statistical Manual of Mental Disorders, 5th Edn. Arlington, VA: American Psychiatric Publishing.
6. Aron, A., and Aron, E. (1986). Love and the Expansion of self: Understanding Attraction and Satisfaction. New York, NY: Hemisphere.
7. Aron, A., Aron, E. N., and Smollan, D. (1992). Inclusion of other in the self scale and the structure of interpersonal closeness. J. Pers. Soc. Psychol. 63, 596-612. doi: 10.1037/0022-3514.63.4.596
8. Aron, A., Aron, E. N., Tudor, M., and Nelson, G. (1991). Close relationships as including other in the self. J. Pers. Soc. Psychol. 60, 241-253. doi: 10.1037/0022-3514.60.2.241
9. Aron, A., Fisher, H. E., Mashek, D. J., Strong, G., Li, H. F., and Brown, L. L. (2005). Reward, motivation, and emotion systems associated with early-stage intense romantic love: an fMRI study. J. Neurophysiol. 94, 327-337. doi: 10.1152/jn.00838.2004
10. Aron, A., Lewandowski, G., Mashek, D., and Aron, E. N. (2013). "The self-expansion model of motivation and cognition in close relationships," in Oxford Handbook of Close Relationships, eds J. A. Simpson and L. Campbell (New York: Oxford), 90-115.
11. Aron, A., Norman, C. C., Aron, E. N., McKenna, C., and Heyman, R. (2000). Couples shared participation in novel and arousing activities and experienced relationship quality. J. Pers. Soc. Psychol. 78, 273-283. doi: 10.1037/0022-3514.78.2.273
12. Aron, A., Paris, M., and Aron, E. N. (1995). Falling in love: prospective studies of self-concept change. J. Pers. Soc. Psychol. 69, 1102-1112. doi: 10.1037/0022-3514.69.6.1102
13. Aron, A. P., Mashek, D. J., and Aron, E. N. (2004). "Closeness as including other in the self," in The Handbook of Closeness and Intimacy, eds D. Mashek and A. Aron (Mahwah, NJ: Lawrence Erlbaum Associates), 27-41.
14. Bartels, A., and Zeki, S. (2000). The neural basis of romantic love. Neuro Report. 11, 3829-3834. doi: 10.1097/00001756-200011270-00046
15. Bartels, A., and Zeki, S. (2004). The neural correlates of maternal and romantic love. Neuroimage 21, 1155-1166. doi: 10.1016/j.neuroimage.2003.11.003
16. Baumeister, R. F., Wotman, S. R., and Stillwell, A. M. (1993). Unrequited love: on heartbreak, anger, guilt, scriptlessness and humiliation. J. Pers. Soc. Psychol. 64, 377-394. doi: 10.1037/0022-3514.64.3.377
17. Berridge, K. C., Robinson, T. E., and Aldridge, J. W. (2009). Dissecting components of reward: 'Liking', 'wanting', and learning. Curr. Opin. Pharmacol. 9, 65-73. doi: 10.1016/j.coph.2008.12.014
18. Bickel, W. K., Johnson, M. W., Koffarnus, M. N., MacKillop, J., and Murphy, J. G. (2014). The behavioral economics of substance use disorders: reinforcement pathologies and their repair. Annu. Rev. Clin. Psychol. 10, 641-677. doi: 10.1146/annurev-clinpsy-032813-153724
19. Bowlby, J. (1969). Attachment and Loss: Vol. 1 Attachment. New York: Basic Books.
20. Bowlby, J. (1973). Attachment and Loss: Vol. 2. Separation. New York: Basic Books.
21. Breiter, H. C., Aharon, I., Kahneman, D., Dale, A., and Shizgal, P. (2001). Functional imaging of neural responses to expectancy and experience of monetary gains and losses. Neuron 30, 619-639. doi: 10.1016/S0896-6273(01)00303-8
22. Breiter, H. C., Gollub, R. L., Weisskoff, R. M., Kennedy, D. N., Makris, N., Berke, J. D., et al. (1997). Acute effects of cocaine on human brain activity and emotion. Neuron 19, 591-611. doi: 10.1016/S0896-6273(00)80374-8
23. Burkett, J. P., and Young, L. J. (2012). The behavioral, anatomical and pharmacological parallels between social attachment, love and addiction. Psychopharmacology (Berl.) 224, 1-26. doi: 10.1007/s00213-012-2794-x
24. Carter, R. (1998). Mapping the Mind. Los Angeles, CA: University of California Press.
25. Cherlin, A. J. (2009). The Marriage-Go-Round: the State of Marriage and the Family in America today. New York: Alfred A. Knopf.
26. Cuzen, N. L., and Stein, D. J. (2014). "Behavioral addiction: the nexus of impulsivity and compulsivity," in Behavioral Addictions: Criteria, Evidence and Treatment, eds K. R. Rosenberg and L. C. Feder (London: Elsevier), 19-34.
27. Daly, M., and Wilson, M. (1983). Sex, Evolution and Behavior, 2nd Edn. Boston: Willard Grant.
28. Delgado, M. R., Nystrom, L. E., Fissel, C., Noll, D. C., and Fiez, J. A. (2000). Tracking the hemodynamic responses to reward and punishment in the striatum. J. Neurophysiol. 84, 3072-3077.
29. Diana, M. (2013). The addicted brain. Front. Psychiatry 4:40. doi: 10.3389/fpsyt.2013.00040
30. Dietrich, A., and McDaniel, W. F. (2004). Endocannabinoids and exercise. Br. J. Sports. Med. 38, 536-541. doi: 10.1136/bjsm.2004.011718
31. DiNardo, J., and Lemieux, T. (2001). Alcohol, marijuana, and American youth: the unintended consequences of government regulation. J. Health. Econ. 5, 991-1010. doi: 10.1016/S0167-6296(01)00102-3
32. Donovan, J. M. (1988). "Assessment of addictive behaviors for relapse prevention," in Assessment of Addictive Behaviours, eds D. M. Donovan and G. A. Marlatt (New York: Guilford), 3-48.
33. Dozier, R. W. (2002). Why We Hate: Understanding, Curbing, and Eliminating hate in Our Selves and our World. New York: Contemporary books.
34. Eisenberger, N. I., Lieberman, M. D., and Williams, K. D. (2003). Does Rejection Hurt? An FMRI study of social exclusion. Science 302, 290-292. doi: 10.1126/science.1089134
35. Elliott, R., Newman, J. L., Longe, O. A., and Deakin, J. F. W. (2003). Differential response patterns in the striatum and orbitofrontal cortex to financial reward in humans: a parametric functional magnetic resonance imaging study. J. Neurosci. 23, 303-307.
36. Fabre-Nys, C., Ohkura, S., and Kendrick, K. M. (1997). Male faces and odors evoke differential patterns of neurochemical release in the mediobasal hypothalamus of the ewe during estrus: an insight into sexual motivation. Eur. J. Neurosci. 9, 1666-1677. doi: 10.1111/j.1460-9568.1997.tb01524.x
37. Fisher, H., Aron, A., and Brown, L. L. (2005). Romantic love: an MRI study of a neural mechanism for mate choice. J. Comp. Neurol. 493, 58-62. doi: 10.1002/cne.20772
38. Fisher, H., Aron, A., and Brown, L. L. (2006). Romantic love: a mammalian brain system for mate choice. Philos. Trans. R. Soc. Lond. B. Biol. Sci. 361, 2173-2186. doi: 10.1098/rstb.2006.1938
39. Fisher, H., Aron, A., Mashek, D., Strong, G., Li, H., and Brown, L. L. (2002). Defining the brain systems of lust, romantic attraction and attachment. Arch. Sex. Behav. 31, 13-19. doi: 10.1023/A:1019888024255
40. Fisher, H., Aron, A., Mashek, D., Strong, G., Li H., and Brown L.L. (2003). Early stage intense romantic love activates cortical-basal-ganglia reward/motivation, emotion and attention systems: an fMRI study of a dynamic network that varies with relationship length, passion intensity and gender. Poster presented at the Annual Meeting of the Society for Neuroscience, New Orleans.
41. Fisher, H. E. (1989). Evolution of human serial pair-bonding. Am. J. Phys. Anthropol. 78, 331-354. doi: 10.1002/ajpa.1330780303
42. Fisher, H. E. (1992). Anatomy of Love: The Natural History of Monogamy, Adultery, and Divorce. New York, NY: W. W. Norton.
43. Fisher, H. E. (1998). Lust, attraction, and attachment in mammalian reproduction. Hum. Nat. 9, 23-52. doi: 10.1007/s12110-998-1010-5
44. Fisher, H. E. (2004). Why we Love: the Nature and Chemistry of Romantic Love. New York: Henry Holt.
45. Fisher, H. E. (2011). "Serial monogamy and clandestine adultery: evolution and consequences of the dual human reproductive strategy," in Applied Evolutionary Psychology, ed. S. C. Roberts (New York, NY: Oxford University Press), 96-111.
46. Fisher, H. E. (2016). Anatomy of Love: a Natural History of Mating, Marriage and Why we Stray, 2nd Edn. New York: WW Norton.
47. Fisher, H. E., Brown, L. L., Aron, A., Strong, G., and Mashek, D. (2010). Reward, addiction, and emotion regulation systems associated with rejection in love. J. Neurophysiol. 104, 51-60. doi: 10.1152/jn.00784.2009
48. Fletcher, G. J. O., Simpson, J. A., Campbell, L., and Overall, N. C. (2015). Pair bonding, romantic love, and evolution: the curious case of Homo sapiens. Perspect. Psychol. Sci. 10, 20-36. doi: 10.1177/1745691614561683
49. Fraley, R. C., and Shaver, P. R. (2000). Adult romantic attachment: theoretical developments, emerging controversies, and unanswered questions. Rev. Gen. Psychol. 4, 132-154. doi: 10.1037//1089-2680.4.2.132
50. Frascella, J., Potenza, M. N., Brown, L. L., and Childress, A. R. (2010). Shared brain vulnerabilities open the way for nonsubstance addictions: caving addiction at a new joint? Ann. N. Y. Acad. Sci. 1187, 294-315. doi: 10.1111/j.1749-6632.2009.05420.x
51. Frayser, S. (1985). Varieties of Sexual Experience: An Anthropological Perspective of Human Sexuality. New Haven: HRAF Press.
52. Gingrich, B., Liu, Y., Cascio, C. Z., and Insel, T. R. (2000). Dopamine D2 receptors in the nucleus accumbens are important for social attachment in female prairie voles (Microtus ochrogaster). Behav. Neurosci. 114, 173-183. doi: 10.1037/0735-7044.114.1.173
53. Goldfarb, A. H., and Jamurtas, A. Z. (1997). Beta-endorphin response to exercise. An update. Sports. Med. 24, 8-16. doi: 10.2165/00007256-199724010-00002
54. Griffin-Shelley, E. (1991). Sex and Love: Addiction, Treatment, and Recovery. Westport, CT: Praeger.
55. Halpern, H. M. (1982). How to Break your Addiction to a Person. New York: McGraw-Hill.
56. Haney, M. (2009). Self-administration of cocaine, cannabis and heroine in the human laboratory: benefits and pitfalls. Addict. Biol. 14, 9-21. doi: 10.1111/j.1369-1600.2008.00121.x
57. Hänninen, V., and Koski-Jännes, A. (1999). Narratives of recovery from addictive behaviors. Addiction 94, 1837-1848. doi: 10.1046/j.1360-0443.1999.941218379.x
58. Harris, H. (1995). "Rethinking heterosexual relationships in polynesia: a case study of mangaia, cook island," in Romantic Passion: A Universal Experience?, ed. W. Jankowiak (New York, NY: Columbia University Press), 95-127.
59. Hatfield, E., and Sprecher, S. (1986). Measuring passionate love in intimate relationships. J. Adolesc. 9, 383-410. doi: 10.1016/S0140-1971(86)80043-4
60. Haylett, S. A., Stephenson, G. M., and Lefever, R. M. H. (2004). Covariation in addictive behaviours: a study of addictive orientations using the Shorter PROMIS Questionnaire. Addict. Behav. 29, 61-71. doi: 10.1016/S0306-4603(03)00083-2
61. Hazan, C., and Diamond, L. M. (2000). The place of attachment in human mating. Rev. Gen. Psychol. 4, 186-204. doi: 10.1037//1089-2680.4.2.186
62. Hazan, C., and Shaver, P. R. (1987). Romantic love conceptualized as an attachment process. J. Pers. Soc. Psychol. 52, 511-524. doi: 10.1037/0022-3514.52.3.511
63. Hoeft, F., Watson, C. L., Kesler, S. R., Bettinger, K. E., and Reiss, A. L. (2008). Gender differences in the mesocorticolimbic system during computer game-play. J. Psychiatr. Res. 42, 253-258. doi: 10.1016/j.jpsychires.2007.11.010
64. Hunter, M. S., Nitschke, C., and Hogan, L. (1981). A scale to measure love addiction. Psychol. Reports 48, 582. doi: 10.2466/pr0.1981.48.2.582
65. Insel, T. R. (2003). Is social attachment an addictive disorder? Physiol. Behav. 79, 351-357. doi: 10.1016/S0031-9384(03)00148-3
66. Insel, T. R., and Young, L. J. (2001). The neurobiology of attachment. Nat. Rev. Neurosci. 2, 129-136. doi: 10.1038/35053579
67. Jordan, H. W., and Howe, G. (1980). De clerambault syndrome (Erotomania): a review and case presentation. J. Natl. Med. Assoc. 72, 979-985.
68. Kellogg, S. H., and Kreek, M. J. (2005). Gradualism, identity, reinforcements, and change. Int. J. Drug Policy 16, 369-375. doi: 10.1016/j.drugpo.2005.08.001
69. Knutson, B., Rick, S., Wimmer, G. E., Prelec, D., and Loewenstein, G. (2007). Natural predictors of purchases. Neuron 53, 147-156. doi: 10.1016/j.neuron.2006.11.010
70. Kolata, G. (2002). Runner's High? Endorphins? Fiction, some scientist say. Sci. Times 21, F1-F6.
71. Koob, G. F., and Volkow, N. D. (2010). Neurocircuitry of addiction. Neuropsychopharmacology 35, 217-238. doi: 10.1038/npp.2009.110
72. Kopelman, M. D., Guinan, E. M., and Lewis, P. D. R. (2008). Delusional memory, confabulation, and frontal lobe dysfunction: a case study of De Clerambault's Syndrome. Neurocase 1, 71-77. doi: 10.1080/13554799508402348
73. Leary, M. R. (2001). Interpersonal Rejection. New York, NY: Oxford University Press.
74. Lewandowski, G. W. Jr. (2009). Promoting positive emotions following relationship dissolution through writing. J. Pos. Psychol. 4, 21-31. doi: 10.1080/17439760802068480
75. Lewandowski, G. W. Jr., and Bizzoco, N. (2007). Addition through subtraction: growth following the dissolution of a low quality relationship. J. Pos. Psychol. 2, 40-54. doi: 10.1080/17439760601069234
76. Lewis, T., Amini, F., and Lannon, R. (2000). A General theory of Love. New York, NY: Random House.
77. Liebowitz, M. R. (1983). The Chemistry of Love. Boston: Little Brown.
78. Liu, Y., Young, K. A., Curtis, J. T., Aragona, B. J., and Wang, Z. (2011). Social bonding decreases the rewarding properties of amphetamine through a dopamine D1 receptor-mediated mechanism. J. Neurosci. 31, 7960-7966. doi: 10.1523/JNEUROSCI.1006-11.2011
79. Lovejoy, O. C. (2009). Reexamining human origins in light of Ardipithecus ramidus. Science 326, 74-78. doi: 10.1126/science.1175834
80. MacDonald, G., and Leary, M. R. (2005). Why does social exclusion hurt? The relationship between social and physical pain. Psychol. Bull. 131, 202-223. doi: 10.1037/0033-2909.131.2.202
81. Marazziti, D., Akiskal, H. S., Rossi, A., and Cassano, G. B. (1999). Alteration of the platelet serotonin transporter in romantic love. Psychol. Med. 29, 741-745. doi: 10.1017/S0033291798007946
82. Marks, I. (1990). Behavioural (non-chemical) addictions. Br. J. Addict. 85, 1389-1394. doi: 10.1111/j.1360-0443.1990.tb01618.x
83. Mattingly, B. A., McIntyre, K. P., and Lewandowski, G. W. Jr. (2012). Approach motivation and the expansion of self in close relationships. Pers. Rel. 19, 113-127. doi: 10.1111/j.1475-6811.2010.01343.x
84. Melis, M., Spiga, S., and Diana, M. (2005). The dopamine hypothesis of drug addiction: hypodopaminergic state. Int. Rev. Neurobiol. 63, 101-154. doi: 10.1016/S0074-7742(05)63005-X
85. Mellody, P., Miller, A. W., and Miller, J. K. (1992). Facing Love Addiction. New York, NY: Harper Collins Publishers.
86. Meloy, J. R. (1998). The Psychology of Stalking: Clinical and Forensic Perspectives. New York, NY: Academic Press.
87. Meloy, J. R., and Fisher, H. E. (2005). Some thoughts on the neurobiology of stalking. J. Forensic. Sci. 50, 1472-1480. doi: 10.1520/JFS2004508
88. Montague, P. R., McClure, S. M., Baldwin, P. R., Phillips, P. E., Budygin, E. A., Stuber, G. D., et al. (2004). Dynamic gain control of dopamine delivery in freely moving animals. J. Neurosci. 24, 1754-1759. doi: 10.1523/JNEUROSCI.4279-03.2004
89. Noriuchi, M., Kikuchi, Y., and Senoo, A. (2008). The functional neuroanatomy of maternal love: mother's response to infant's attachment behaviors. Biol. Psychiatry 63, 415-423. doi: 10.1016/j.biopsych.2007.05.018
90. Ortigue, S., Bianchi-Demicheli, F., Hamilton, A. F., and Grafton, S. T. (2007). The neural basis of love as a subliminal prime: an event-related functional magnetic resonance imaging study. J. Cogn. Neurosci. 19, 1218-1230. doi: 10.1162/jocn.2007.19.7.1218
91. Panksepp, J. (2003a). At the interface of the affective, behavioral, and cognitive neurosciences: decoding the emotional feelings of the brain. Brain Cogn. 52, 4-14. doi: 10.1016/S0278-2626(03)00003-4
92. Panksepp, J. (2003b). Neuroscience. Feeling the pain of social loss. Science 302, 237-239. doi: 10.1126/science.1091062
93. Panksepp, J., Knutson, B., and Burgdorf, J. (2002). The role of brain emotional systems in addictions: a neuro-evolutionary perspective and new 'self-report' animal model. Addiction 97, 459-469. doi: 10.1046/j.1360-0443.2002.00025.x
94. Peele, S. (1975). Love and Addiction. New York, NY: Taplinger Publishing Company.
95. Reno, P. L., Meindl, R. S., McCollum, M. A., and Lovejoy, C. O. (2003). Sexual dimorphism in Australopithecus afarensis was similar to that of modern humans. Proc. Natl. Acad. Sci. U.S.A. 100, 9404-9409. doi: 10.1073/pnas.1133180100
96. Reynaud, M. L., Karila, L., Blecha, L., and Benyamina, A. (2010). Is love passion an addictive disorder? Am. J. Drug Alcohol. Abuse 36, 261-267. doi: 10.3109/00952990.2010.495183
97. Robinson, D. L., Heien, M. L., and Wightman, R. M. (2002). Frequency of dopamine concentration transients increases in dorsal and ventral striatum of male rats during introduction of conspecifics. J. Neurosci. 22, 10477-10486.
98. Rosenberg, K. P., and Feder, L. C. (2014). "Forward to: behavioral addictions," in Criteria, Evidence and Treatment, eds K. R. Rosenberg and L. C. Feder (London: Elsevier), 13.
99. Rosenthal, N. E. (2002). The Emotional Revolution: How the New Science of Feelings can Transform Your Life. New York: Citadel Press Books.
100. Salvy, S., Nitecki, L. A., and Epstein, L. H. (2009). Do social activities substitute for food in youth? Ann. Behav. Med. 38, 205-212. doi: 10.1007/s12160-009-9145-0
101. Schaef, A. W. (1989). Escape from Intimacy: The Pseudo-Relationship Addictions. San Francisco: Harper & Row.
102. Schultz, W. (2000). Multiple reward signals in the brain. Nat. Rev. Neurosci. 1, 199-207. doi: 10.1038/35044563
103. Shiffman, S. (1989). Tobacco "chippers"-individual differences in tobacco dependence. Psychopharmacology (Berl). 97, 539-547. doi: 10.1007/BF00439561
104. Shiffman, S., and Paty, J. (2006). Smoking patterns and dependence: contrasting chippers and heavy smokers. J. Abnorm. Psychol. 115, 509-523. doi: 10.1037/0021-843X.115.3.509
105. Shiffman, S., Paty, J. A., Gnys, M., Kassel, J. D., and Elash, C. (1995). Nicotine withdrawal in chippers, and regular smokers: subjective, and cognitive effects. Health Psychol. 14, 301-309. doi: 10.1037/0278-6133.14.4.301
106. Strong, G., and Aron, A. (2006). "The effect of shared participation in novel and challenging activities on experienced relationship quality: is it mediated by high positive affect?," in Connecting Intrapersonal and Interpersonal Processes, eds K. Vohs and E. Finkel (New York, NY: Guilford), 342-359.
107. Tennov, D. (1979). Love and Limerence: the Experience of Being in Love. New York: Stein and Day.
108. Thayer, R. E. (1996). The Origin of Everyday Moods: Managing Energy, Tension and Stress. New York: Oxford University Press.
109. Tucker, D. M., Luu, P., and Derryberry, D. (2005). Love hurts: the evolution of empathic concern through the encephalization of nociceptive capacity. Dev. Psychopathol. 17, 699-713. doi: 10.1017/S0954579405050339
110. Vaillant, G. (1983). The Natural History of Alcoholism. Cambridge: Harvard University Press.
111. Van den Berghe, P. L. (1979). Human Family Systems: An Evolutionary View. Westport, CT: Greenwood Press.
112. Volkow, N. D., Fowler, S. J., Wang, G. J., Swanson, J. M., and Telang, F. (2007). Dopamine in drug abuse and addiction: results of imaging studies and treatment implications. Arch. Neurol. 64, 1575-1579. doi: 10.1001/archneur.64.11.1575
113. Wang, G. J., Volkow, N. D., Telang, F., Jayne, M., Ma, J., Rao, M., et al. (2004). Exposure to appetitive food stimuli markedly activates the human brain. Neuroimage 21, 1790-1797. doi: 10.1016/j.neuroimage.2003.11.026
114. Wang, Z., Yu, G., Cascio, C., Liu, Y., Gingrich, B., and Insel, T. R. (1999). Dopamine D2 receptor-mediated regulation of partner preferences in female prairie voles (Microtus ochrogaster): a mechanism for pair bonding? Behav. Neurosci. 113, 602-611. doi: 10.1037/0735-7044.113.3.602
115. Xu, X., Aron, A., Brown, L. L., Cao, G., Feng, T., and Weng, X. (2011). Reward and motivation systems: a brain mapping study of early-stage intense romantic love in Chinese participants. Hum. Brain Mapp. 32, 49-57. doi: 10.1002/hbm.21017
116. Xu, X., Aron, A., Westmaas, J. L., Wang, J., and Sweet, L. H. (2014). An fMRI study of nicotine-deprived smokers' reactivity to smoking cues during novel/exciting activity. PLoS ONE 9:e94598. doi: 10.1371/journal.pone.0094598
117. Xu, X., Floyd, A. H. L., Westmaas, J. L., and Aron, A. (2010). Self-expansion and smoking abstinence. Addict. Behav. 35, 295-301. doi: 10.1016/j.addbeh.2009.10.019
118. Xu, X., Wang, J., Lei, W., Aron, A., Westmaas, L., and Weng, X. (2012). Intense passionate love attenuates cigarette cue-reactivity in nicotine-deprived smokers: an fMRI study. PLoS ONE 7:e42235. doi: 10.1371/journal.pone.0042235
119. Younger, J., Aron, A., Parke, S., Chatterjee, N., and Mackey, S. (2010). Viewing pictures of a romantic partner reduces experimental pain: involvement of neural reward systems. PLoS ONE 5:e13309. doi: 10.1371/journal.pone.0013309
120. Zeki, S., and Romaya, J. P. (2010). The brain reaction to viewing faces of opposite and same sex romantic partners. PLoS ONE 5:e15802. doi: 10.1371/journal.pone.0015802