The role of brain emotional systems in addictions: A neuro-evolutionary perspective and new 'self-report' animal model

Addiction

Volumn 97, Issue 4, 2002, Pages 459-469

  Panksepp, Jaak ^a   Knutson, Brian ^b   Burgdorf, Jeff ^a  

^a BOWLING GREEN STATE UNIVERSITY   (United States)

^b NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

Author keywords

Addiction; Appetitive motivation; Emotion; Evolution; Seeking; Social behavior; Ultrasonic vocalizations

Indexed keywords

ANIMAL MODEL; ARTICLE; DRUG DEPENDENCE; DRUG WITHDRAWAL; EMOTION; EVOLUTION; MEDICAL RESEARCH; NONHUMAN; SOCIAL BEHAVIOR;

ANIMALS; BEHAVIOR, ADDICTIVE; BRAIN CHEMISTRY; EMOTIONS; EVOLUTION; MODELS, ANIMAL; SOCIOLOGY; SUBSTANCE-RELATED DISORDERS;

EID: 0036213136     PISSN: 09652140     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1360-0443.2002.00025.x     Document Type: Article

References (90)

1. Neuropeptides and sexual behavior
2. Ultrasonic vocalizations in rat sexual behavior
3. Psychomotor stimulants, social deprivation, and play in juvenile rats
4. Food reward: Brain substrates of wanting and liking
5. What is the role of dopamine in reward: Hedonic impact, reward learning, or incentive salience?
6. Twenty two kHz alarm cries to presentations of a predator, by laboratory rats living in visible burrow systems
7. On the significance of similarities between ultrasonic vocalizations of infant and adult rats
8. Subjective responses to d-amphetamine alone and after pimozide treatment in normal, healthy volunteers
9. Anticipation of rewarding brain stimulation evokes ultrasonic vocalizations in rats
10. Nucleus accumbens amphetamine microinjections unconditionally elicit 50kHz ultrasonic vocalizations in rats
11. Ultrasonic vocalizations index pharmacological aversion in adult rats
12. Interpersonal style differences among drug abusers
13. Quantitative brain magnetic resonance imaging in attention-deficit hyperactivity disorder
14. Appetites and aversions as constituents of instincts
15. Kin interaction enhances morphine analgesia in male mice
16. Longitudinal neuronal organization of defensive reactions in the midbrain periaqueductal gray region of the rat
17. Facial expression and emotion
18. The structure of current affect: Controversies and emerging consensus
19. Self-administration of cocaine by humans: A laboratory perspective
20. Maternal care and the development of stress responses
21. High-frequency ultrasonic vocalization induced by intracerebral glutamate in rats
22. Opiate addiction and the locus coeruleus: The clinical utility of clonidine, naltrexone, methadone, and buprenorphine
23. Social deprivation in monkeys
24. Nonhuman primate model of alcohol abuse: Effects of early experience, personality, and stress on alcohol consumption
25. Behavioral disinhibition and the development of substance-use disorders: Findings from the Minnesota Twin Family study
26. The role of nucleus accumbens dopamine in motivated behavior: A unifying interpretation with special reference to reward-seeking
27. Increased sensitivity to amphetamine and reward-related stimuli following social isolation in rats: Possible disruption of dopamine-dependent mechanisms of the nucleus accumbens
28. Interactions between dopamine and excitatory amino acids in behavioral sensitization to psycho-stimulants
29. Functional specificity of ventral striatal compartments in appetitive behaviors
30. Beta-endorphin concentrations in cerebrospinal fluid of monkeys are influenced by grooming relationships
31. Anticipation of play elicits high-frequency ultrasonic vocalizations in young rats
32. High-frequency ultrasonic vocalizations index conditioned pharmacological reward in rats
33. Cocaine, dopamine, and the endogenous opioid system
34. Drug dependence: Stress and dysregulation of brain reward pathways
35. The reinforcing and subjective effects of morphine in post-addicts: A dose-response study
36. Emotion circuits in the brain
37. Addiction is a brain disease, and it matters
38. A catalytic antibody against cocaine prevents cocaine's reinforcing and toxic effects in rats
39. Aggression, anxiety and vocalizations in animals: GABA and 5-HT anxiolytics
40. Integration of generalized vulnerability to drug and alcohol addiction
41. Psychoactive drug use in evolutionary perspective
42. Chronic intermittent amphetamine pretreatment enhances future appetitive behavior for drug-, food- and sexual-reward: Interaction with environmental variables
43. Toward a general psychobiological theory of emotions
44. Neurochemical control of moods and emotions: Amino acids to neuropeptides
45. The long-term psychobiological consequences of infant emotions: Prescriptions for the 21st century
46. The long-term psychobioiogical consequences of infant emotions: Prescriptions for the twenty-first century
47. An autoradiographic map of 3H diprenorphine binding in the rat brain: Effects of social interaction
48. Laughing rats? Playful tickling arouses high frequency ultrasonic chirping in young rodents
49. 50-kHz chirping (laughter?) in response to conditioned and unconditioned tickle-induced reward in rats: Effects of social housing and genetic variables
50. The biology of social attachments: Opiates alleviate separation distress
51. Endogenous opioids and social behavior
52. Opiates and play dominance in juveniles rats
53. Toward a neuroscience of emotion: Epigenetic foundations of emotional development
54. Neural and neurochemical control of the separation distress call
55. The seven sins of evolutionary psychology
56. Dopamine fluctuations in the nucleus accumbens during maintenance, extinction, and reinstatement of intravenous D-amphetamine self-administration
57. The neural basis of drug craving: An incentive-sensitization theory of addiction
58. Attenuation of the euphoric effects of cocaine by the dopamine DJ/D5 antagonist ecopipam
59. The role of brain norepinephrine in clonidine suppression f isolation-induced distress in the domestic chick
60. Role of oxytocin in the neuroadaptation to drugs of abuse
61. Vocal affect expression: A review and a model for future research
62. Predictive reward signal of dopamine neurons
63. Neural substrates of drug craving and relapse in drug addiction
64. Molecular mechanisms of drug reinforcement and addiction
65. Chronic morphine induces visible changes in the morphology of mesolimbic dopamine neurons
66. Beyond stress and arousal: A reconceptualization of alcohol-emotion relations with reference to psychophysiological methods
67. Alcohol and human emotion: A multidimensional analysis incorporating startle-probe methodology
68. Analysis of ultrasonic vocalizations emitted by intruders during aggressive encounters among rats (Rattus norvegicus)
69. Inhibition of shock-elicited ultrasonic vocalization by opioid peptides in the rat: A psychotropic effect
70. The pharmacology of endorphin modulation of chick distress vocalization
71. Ultrasounds during morphine withdrawal in rats
72. Genetical and environmental influences on religious interests, attitudes, and values: A study of twins reared apart and together
73. Toward a consensual structure of mood
74. Dissociation of consummatory and vocal components of feeding in squirrel monkeys treated with benzodiazepines and alcohol
75. Clinical and psychological effects of marihuana
76. The role of cultural and social factors in the cause of addictive disorders
77. Neuroadaptations involved in amphetamine and cocaine addiction
78. The related roles of dopamine and glutamate in the initiation of 50 kHz ultrasonic calls in adult rats
79. Drug-activation of brain reward pathways
80. Elevations of nucleus accumbens dopamine and DOPAC levels during intravenous heroin self-administration
81. Brain dopamine and reward
82. Effect of social isolation on the reinforcing properties of morphine in the conditioned place preference test
83. The midbrain central gray as a highly sensitive neural structure for the production of ultrasonic vocalization in the rat
84. The role of affective processes in learning and motivation