TLR4/MyD88/NF-κB signaling and PPAR-γ within the paraventricular nucleus are involved in the effects of telmisartan in hypertension

Toxicology and Applied Pharmacology

Volumn 305, Issue , 2016, Pages 93-102

  Li, Hong Bao ^a   Li, Xiang ^a   Huo, Chan Juan ^a   Su, Qing ^a   Guo, Jing ^a   Yuan, Zu Yi ^b   Zhu, Guo Qing ^c   Shi, Xiao Lian ^a   Liu, Jin Jun ^a   Kang, Yu Ming ^a  

^a MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF XI AN JIAOTONG UNIVERSITY   (China)

^c NANJING MEDICAL UNIVERSITY   (China)

Author keywords

AT1 receptor; Hypertension; Paraventricular nucleus; PPAR ; Toll like receptor 4

Indexed keywords

2 CHLORO 5 NITROBENZANILIDE; ANGIOTENSIN 1 RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LOSARTAN; MYELOID DIFFERENTIATION FACTOR 88; NORADRENALIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TELMISARTAN; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; ANTIHYPERTENSIVE AGENT; BENZIMIDAZOLE DERIVATIVE; BENZOIC ACID DERIVATIVE; CYTOKINE; MYD88 PROTEIN, RAT; NOS2 PROTEIN, RAT; TLR4 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DRUG EFFECT; ENCEPHALITIS; HEART VENTRICLE HYPERTROPHY; HYPERTENSION; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; HYPOTHALAMUS; MEAN ARTERIAL PRESSURE; NONHUMAN; NORADRENALIN BLOOD LEVEL; OSMOTIC MINIPUMP; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SPONTANEOUSLY HYPERTENSIVE RAT; WISTAR KYOTO RAT; ANIMAL; ARTERIAL PRESSURE; BLOOD; CARDIOMEGALY; DRUG EFFECTS; GENETICS; MALE; METABOLISM;

ANIMALS; ANTIHYPERTENSIVE AGENTS; ARTERIAL PRESSURE; BENZIMIDAZOLES; BENZOATES; CARDIOMEGALY; CYTOKINES; HYPERTENSION; MALE; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; NOREPINEPHRINE; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; PPAR GAMMA; RATS, INBRED SHR; RATS, INBRED WKY; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 84973887152     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2016.06.014     Document Type: Article

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