Toll-like receptor 4 inhibition within the paraventricular nucleus attenuates blood pressure and inflammatory response in a genetic model of hypertension

Journal of Neuroinflammation

Volumn 12, Issue 1, 2015, Pages

  Dange, Rahul B ^a   Agarwal, Deepmala ^b   Teruyama, Ryoichi ^c   Francis, Joseph ^a  

^a LOUISIANA STATE UNIVERSITY   (United States)

^b PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

^c LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

Cytokines; Hypertension; IL 10; NF B; Paraventricular nucleus; TLR4

Indexed keywords

HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 1BETA; NORADRENALIN; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR AFFECTING AGENT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VIRAL INHIBITORY PEPTIDE; CYTOKINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE REGULATION; BLOOD SAMPLING; BRAIN SLICE; CONTROLLED STUDY; ESSENTIAL HYPERTENSION; GENETIC MODEL; HEART VENTRICLE HYPERTROPHY; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; MALE; MEAN ARTERIAL PRESSURE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; NORADRENALIN BLOOD LEVEL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; SYMPATHETIC TONE; TELEMETRY; TREATMENT DURATION; UPREGULATION; WISTAR KYOTO RAT; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD PRESSURE; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; GENETICS; HYPERTENSION; INFLAMMATION; METABOLISM; PHYSIOLOGY;

ANIMALS; BLOOD PRESSURE; CYTOKINES; DISEASE MODELS, ANIMAL; HMGB1 PROTEIN; HYPERTENSION; INFLAMMATION; MALE; NITRIC OXIDE SYNTHASE TYPE II; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; RATS; RATS, INBRED SHR; RATS, INBRED WKY; TOLL-LIKE RECEPTOR 4;

EID: 84924106937     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-015-0242-7     Document Type: Article

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