Development of a Rapid Microbore Metabolic Profiling Ultraperformance Liquid Chromatography-Mass Spectrometry Approach for High-Throughput Phenotyping Studies

Analytical Chemistry

Volumn 88, Issue 11, 2016, Pages 5742-5751

  Gray, Nicola ^a   Adesina Georgiadis, Kyrillos ^a   Chekmeneva, Elena ^a   Plumb, Robert S ^a   Wilson, Ian D ^a   Nicholson, Jeremy K ^a,b  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BODY FLUIDS; CHROMATOGRAPHY; GRADIENT METHODS; MASS SPECTROMETRY; METABOLISM; ORGANIC POLYMERS; SPECTROMETRY; THROUGHPUT;

CONVENTIONAL METHODS; DIRECT INFUSIONS; GRADIENT APPROACH; HIGH-THROUGHPUT PHENOTYPING; METABOLIC PROFILING; METABONOMIC ANALYSIS; SENSITIVE METHOD; ULTRA-PERFORMANCE LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY;

LIQUID CHROMATOGRAPHY;

2-BROMOPHENOL; PARACETAMOL; PHENOL DERIVATIVE;

ANIMAL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH THROUGHPUT SCREENING; MASS SPECTROMETRY; METABOLISM; METABOLOME; METABOLOMICS; PHENOTYPE; RAT; URINE;

ACETAMINOPHEN; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HIGH-THROUGHPUT SCREENING ASSAYS; MASS SPECTROMETRY; METABOLOME; METABOLOMICS; PHENOLS; PHENOTYPE; RATS;

EID: 84973652811     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/acs.analchem.6b00038     Document Type: Article

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