-
1
-
-
48249125791
-
Malignant gliomas in adults
-
Wen PY, Kesari S, Malignant gliomas in adults. N Engl J Med. 2008; 359: 492–507. doi: 10.1056/NEJMra0708126 18669428
-
(2008)
N Engl J Med
, vol.359
, pp. 492-507
-
-
Wen, P.Y.1
Kesari, S.2
-
2
-
-
65349121788
-
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
-
Stupp R, Hegi ME, Mason WP, van den Bent MJ, Taphoorn MJ, et al. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol. 2009; 10: 459–466. doi: 10.1016/S1470-2045(09)70025-7 19269895
-
(2009)
Lancet Oncol
, vol.10
, pp. 459-466
-
-
Stupp, R.1
Hegi, M.E.2
Mason, W.P.3
van den Bent, M.J.4
Taphoorn, M.J.5
-
3
-
-
35949002429
-
Malignant astrocytic glioma: genetics, biology, and paths to treatment
-
Furnari FB, Fenton T, Bachoo RM, Mukasa A, Stommel JM, et al. Malignant astrocytic glioma: genetics, biology, and paths to treatment. Genes Dev. 2007; 21: 2683–2710. 17974913
-
(2007)
Genes Dev
, vol.21
, pp. 2683-2710
-
-
Furnari, F.B.1
Fenton, T.2
Bachoo, R.M.3
Mukasa, A.4
Stommel, J.M.5
-
4
-
-
17144398831
-
Possible future issues in the treatment of glioblastomas: special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis
-
Lefranc F, Brotchi J, Kiss R, Possible future issues in the treatment of glioblastomas: special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis. J Clin Oncol. 2005; 23: 2411–2422. 15800333
-
(2005)
J Clin Oncol
, vol.23
, pp. 2411-2422
-
-
Lefranc, F.1
Brotchi, J.2
Kiss, R.3
-
5
-
-
84860199032
-
Interferon regulatory factor 7 regulates glioma stem cells via interleukin-6 and Notch signalling
-
Jin X, Kim SH, Jeon HM, Beck S, Sohn YW, et al. Interferon regulatory factor 7 regulates glioma stem cells via interleukin-6 and Notch signalling. Brain. 2012; 135: 1055–1069. doi: 10.1093/brain/aws028 22434214
-
(2012)
Brain
, vol.135
, pp. 1055-1069
-
-
Jin, X.1
Kim, S.H.2
Jeon, H.M.3
Beck, S.4
Sohn, Y.W.5
-
6
-
-
79551600015
-
Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways
-
Takebe N, Harris PJ, Warren RQ, Ivy SP, Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways. Nat Rev Clin Oncol. 2011; 8: 97–106. doi: 10.1038/nrclinonc.2010.196 21151206
-
(2011)
Nat Rev Clin Oncol
, vol.8
, pp. 97-106
-
-
Takebe, N.1
Harris, P.J.2
Warren, R.Q.3
Ivy, S.P.4
-
7
-
-
33646358694
-
Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
-
Lee J, Kotliarova S, Kotliarov Y, Li A, Su Q, et al. Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines. Cancer Cell. 2006; 9: 391–403. 16697959
-
(2006)
Cancer Cell
, vol.9
, pp. 391-403
-
-
Lee, J.1
Kotliarova, S.2
Kotliarov, Y.3
Li, A.4
Su, Q.5
-
8
-
-
33645732219
-
Molecular pathology of malignant gliomas
-
Louis DN, Molecular pathology of malignant gliomas. Annu Rev Pathol. 2006; 1: 97–117. 18039109
-
(2006)
Annu Rev Pathol
, vol.1
, pp. 97-117
-
-
Louis, D.N.1
-
9
-
-
66049085403
-
Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens
-
Pollard SM, Yoshikawa K, Clarke ID, Danovi D, Stricker S, et al. Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens. Cell Stem Cell. 2009; 4: 568–580. doi: 10.1016/j.stem.2009.03.014 19497285
-
(2009)
Cell Stem Cell
, vol.4
, pp. 568-580
-
-
Pollard, S.M.1
Yoshikawa, K.2
Clarke, I.D.3
Danovi, D.4
Stricker, S.5
-
10
-
-
84899990827
-
Pathological features of highly invasive glioma stem cells in a mouse xenograft model
-
Sadahiro H, Yoshikawa K, Ideguchi M, Kajiwara K, Ishii A, et al. Pathological features of highly invasive glioma stem cells in a mouse xenograft model. Brain Tumor Pathol. 2014; 31: 77–84. doi: 10.1007/s10014-013-0149-x 23670138
-
(2014)
Brain Tumor Pathol
, vol.31
, pp. 77-84
-
-
Sadahiro, H.1
Yoshikawa, K.2
Ideguchi, M.3
Kajiwara, K.4
Ishii, A.5
-
11
-
-
0034712047
-
Mammalian neural stem cells
-
Gage FH, Mammalian neural stem cells. Science. 2000; 287: 1433–1438. 10688783.
-
(2000)
Science
, vol.287
, pp. 1433-1438
-
-
Gage, F.H.1
-
12
-
-
77649100933
-
Targeting A20 decreases glioma stem cell survival and tumor growth
-
Hjelmeland AB, Wu Q, Wickman S, Eyler C, Heddleston J, et al. Targeting A20 decreases glioma stem cell survival and tumor growth. PLoS Biol. 2010; 8: e1000319. doi: 10.1371/journal.pbio.1000319 20186265
-
(2010)
PLoS Biol
, vol.8
, pp. 1000319
-
-
Hjelmeland, A.B.1
Wu, Q.2
Wickman, S.3
Eyler, C.4
Heddleston, J.5
-
13
-
-
84907082116
-
CPEB1 modulates differentiation of glioma stem cells via downregulation of HES1 and SIRT1 expression
-
Yin J, Park G, Lee JE, Park JY, Kim TH, et al. CPEB1 modulates differentiation of glioma stem cells via downregulation of HES1 and SIRT1 expression. Oncotarget. 2014; 5: 6756–6769. 25216517
-
(2014)
Oncotarget
, vol.5
, pp. 6756-6769
-
-
Yin, J.1
Park, G.2
Lee, J.E.3
Park, J.Y.4
Kim, T.H.5
-
14
-
-
33845785589
-
Differentiation profile of brain tumor stem cells: a comparative study with neural stem
-
Zhang QB, Ji XY, Huang Q, Dong J, Zhu YD, et al. Differentiation profile of brain tumor stem cells: a comparative study with neural stem cells. 2006; 16: 909–915.
-
(2006)
cells
, vol.16
, pp. 909-915
-
-
Zhang, Q.B.1
Ji, X.Y.2
Huang, Q.3
Dong, J.4
Zhu, Y.D.5
-
15
-
-
0034517812
-
Noggin antagonizes BMP signaling to create a niche for adult neurogenesis
-
Lim DA, Tramontin AD, Trevejo JM, Herrera DG, Garcia-Verdugo JM, et al. Noggin antagonizes BMP signaling to create a niche for adult neurogenesis. Neuron. 2000; 28: 713–726. 11163261
-
(2000)
Neuron
, vol.28
, pp. 713-726
-
-
Lim, D.A.1
Tramontin, A.D.2
Trevejo, J.M.3
Herrera, D.G.4
Garcia-Verdugo, J.M.5
-
16
-
-
0036668287
-
The control of neural stem cells by morphogenic signals
-
Panchision DM, McKay RD, The control of neural stem cells by morphogenic signals. Curr Opin Genet Dev. 2002; 12: 478–487. 12100896
-
(2002)
Curr Opin Genet Dev
, vol.12
, pp. 478-487
-
-
Panchision, D.M.1
McKay, R.D.2
-
17
-
-
33845610993
-
Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells
-
Piccirillo SG, Reynolds BA, Zanetti N, Lamorte G, Binda E, et al. Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells. Nature. 2006; 444: 761–765. 17151667
-
(2006)
Nature
, vol.444
, pp. 761-765
-
-
Piccirillo, S.G.1
Reynolds, B.A.2
Zanetti, N.3
Lamorte, G.4
Binda, E.5
-
18
-
-
0032510679
-
Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases
-
Nagane M, Levitzki A, Gazit A, Cavenee WK, Huang HJ, Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases. Proc Natl Acad Sci U S A. 1998; 95: 5724–5729. 9576951
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 5724-5729
-
-
Nagane, M.1
Levitzki, A.2
Gazit, A.3
Cavenee, W.K.4
Huang, H.J.5
-
19
-
-
0034865816
-
Human glioblastoma xenografts overexpressing a tumor-specific mutant epidermal growth factor receptor sensitized to cisplatin by the AG1478 tyrosine kinase inhibitor
-
Nagane M, Narita Y, Mishima K, Levitzki A, Burgess AW, et al. Human glioblastoma xenografts overexpressing a tumor-specific mutant epidermal growth factor receptor sensitized to cisplatin by the AG1478 tyrosine kinase inhibitor. J Neurosurg. 2001; 95: 472–479. 11565870
-
(2001)
J Neurosurg
, vol.95
, pp. 472-479
-
-
Nagane, M.1
Narita, Y.2
Mishima, K.3
Levitzki, A.4
Burgess, A.W.5
-
20
-
-
67349137902
-
The EGFRvIII variant in glioblastoma multiforme
-
Gan HK, Kaye AH, Luwor RB, The EGFRvIII variant in glioblastoma multiforme. J Clin Neurosci. 2009; 16: 748–754. doi: 10.1016/j.jocn.2008.12.005 19324552
-
(2009)
J Clin Neurosci
, vol.16
, pp. 748-754
-
-
Gan, H.K.1
Kaye, A.H.2
Luwor, R.B.3
-
21
-
-
61449191698
-
EGFRvIII expression and PTEN loss synergistically induce chromosomal instability and glial tumors
-
Li L, Dutra A, Pak E, Labrie JE, Gerstein RM, et al. EGFRvIII expression and PTEN loss synergistically induce chromosomal instability and glial tumors. Neuro Oncol. 2009;11: 9–21. doi: 10.1215/15228517-2008-081 18812521
-
(2009)
Neuro Oncol
, vol.11
, pp. 9-21
-
-
Li, L.1
Dutra, A.2
Pak, E.3
Labrie, J.E.4
Gerstein, R.M.5
-
22
-
-
3042581834
-
Mutant epidermal growth factor receptor displays increased signaling through the phosphatidylinositol-3 kinase/AKT pathway and promotes radioresistance in cells of astrocytic origin
-
Li B, Yuan M, Kim IA, Chang CM, Bernhard EJ, et al. Mutant epidermal growth factor receptor displays increased signaling through the phosphatidylinositol-3 kinase/AKT pathway and promotes radioresistance in cells of astrocytic origin. Oncogene. 2004; 23: 4594–4602. 15077177
-
(2004)
Oncogene
, vol.23
, pp. 4594-4602
-
-
Li, B.1
Yuan, M.2
Kim, I.A.3
Chang, C.M.4
Bernhard, E.J.5
-
23
-
-
0037112423
-
Mutant epidermal growth factor receptor signaling down-regulates p27 through activation of the phosphatidylinositol 3-kinase/Akt pathway in glioblastomas
-
Narita Y, Nagane M, Mishima K, Huang HJ, Furnari FB, et al. Mutant epidermal growth factor receptor signaling down-regulates p27 through activation of the phosphatidylinositol 3-kinase/Akt pathway in glioblastomas. Cancer Res. 2002; 62: 6764–6769. 12438278
-
(2002)
Cancer Res
, vol.62
, pp. 6764-6769
-
-
Narita, Y.1
Nagane, M.2
Mishima, K.3
Huang, H.J.4
Furnari, F.B.5
-
24
-
-
70249145117
-
EGFRvIII-induced estrogen-independence, tamoxifen-resistance phenotype correlates with PgR expression and modulation of apoptotic molecules in breast cancer
-
Zhang Y, Su H, Rahimi M, Tochihara R, Tang C, EGFRvIII-induced estrogen-independence, tamoxifen-resistance phenotype correlates with PgR expression and modulation of apoptotic molecules in breast cancer. Int J Cancer. 2009; 125: 2021–2028. doi: 10.1002/ijc.24540 19588487
-
(2009)
Int J Cancer
, vol.125
, pp. 2021-2028
-
-
Zhang, Y.1
Su, H.2
Rahimi, M.3
Tochihara, R.4
Tang, C.5
-
25
-
-
84894288412
-
Targeting a glioblastoma cancer stem-cell population defined by EGF receptor variant III
-
Emlet DR, Gupta P, Holgado-Madruga M, Del Vecchio CA, Mitra SS, et al. Targeting a glioblastoma cancer stem-cell population defined by EGF receptor variant III. Cancer Res. 2014; 74: 1238–1249. doi: 10.1158/0008-5472.CAN-13-1407 24366881
-
(2014)
Cancer Res
, vol.74
, pp. 1238-1249
-
-
Emlet, D.R.1
Gupta, P.2
Holgado-Madruga, M.3
Del Vecchio, C.A.4
Mitra, S.S.5
-
26
-
-
84860356630
-
Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth
-
Hamerlik P, Lathia JD, Rasmussen R, Wu Q, Bartkova J, et al. Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth. J Exp Med. 2012; 209: 507–520. doi: 10.1084/jem.20111424 22393126
-
(2012)
J Exp Med
, vol.209
, pp. 507-520
-
-
Hamerlik, P.1
Lathia, J.D.2
Rasmussen, R.3
Wu, Q.4
Bartkova, J.5
-
27
-
-
70350497349
-
Autocrine TGF-beta signaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors
-
Ikushima H, Todo T, Ino Y, Takahashi M, Miyazawa K, et al. Autocrine TGF-beta signaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors. Cell Stem Cell. 2009; 5: 504–514. doi: 10.1016/j.stem.2009.08.018 19896441
-
(2009)
Cell Stem Cell
, vol.5
, pp. 504-514
-
-
Ikushima, H.1
Todo, T.2
Ino, Y.3
Takahashi, M.4
Miyazawa, K.5
-
28
-
-
84900796733
-
Glioma cancer stem cells secrete Gremlin1 to promote their maintenance within the tumor hierarchy
-
Yan K, Wu Q, Yan DH, Lee CH, Rahim N, et al. Glioma cancer stem cells secrete Gremlin1 to promote their maintenance within the tumor hierarchy. Genes Dev. 2014; 28: 1085–1100. doi: 10.1101/gad.235515.113 24788093
-
(2014)
Genes Dev
, vol.28
, pp. 1085-1100
-
-
Yan, K.1
Wu, Q.2
Yan, D.H.3
Lee, C.H.4
Rahim, N.5
-
29
-
-
79958265710
-
Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast
-
Scheel C, Eaton EN, Li SH, Chaffer CL, Reinhardt F, et al. Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast. Cell. 2011; 145: 926–940. doi: 10.1016/j.cell.2011.04.029 21663795
-
(2011)
Cell
, vol.145
, pp. 926-940
-
-
Scheel, C.1
Eaton, E.N.2
Li, S.H.3
Chaffer, C.L.4
Reinhardt, F.5
-
30
-
-
70450258365
-
Vascular niche factor PEDF modulates Notch-dependent stemness in the adult subependymal zone
-
Andreu-Agullo C, Morante-Redolat JM, Delgado AC, Farinas I, Vascular niche factor PEDF modulates Notch-dependent stemness in the adult subependymal zone. Nat Neurosci. 2009; 12: 1514–1523. doi: 10.1038/nn.2437 19898467
-
(2009)
Nat Neurosci
, vol.12
, pp. 1514-1523
-
-
Andreu-Agullo, C.1
Morante-Redolat, J.M.2
Delgado, A.C.3
Farinas, I.4
-
31
-
-
84885356671
-
EGFR phosphorylates tumor-derived EGFRvIII driving STAT3/5 and progression in glioblastoma
-
Fan QW, Cheng CK, Gustafson WC, Charron E, Zipper P, et al. EGFR phosphorylates tumor-derived EGFRvIII driving STAT3/5 and progression in glioblastoma. Cancer Cell. 2013; 24: 438–449. doi: 10.1016/j.ccr.2013.09.004 24135280
-
(2013)
Cancer Cell
, vol.24
, pp. 438-449
-
-
Fan, Q.W.1
Cheng, C.K.2
Gustafson, W.C.3
Charron, E.4
Zipper, P.5
-
32
-
-
39449093328
-
Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway
-
de la Iglesia N, Konopka G, Puram SV, Chan JA, Bachoo RM, et al. Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway. Genes Dev. 2008; 22: 449–462. doi: 10.1101/gad.1606508 18258752
-
(2008)
Genes Dev
, vol.22
, pp. 449-462
-
-
de la Iglesia, N.1
Konopka, G.2
Puram, S.V.3
Chan, J.A.4
Bachoo, R.M.5
-
33
-
-
0033538517
-
Pigment epithelium-derived factor: a potent inhibitor of angiogenesis
-
Dawson DW, Volpert OV, Gillis P, Crawford SE, Xu H, et al. Pigment epithelium-derived factor: a potent inhibitor of angiogenesis. Science. 1999; 285: 245–248. 10398599
-
(1999)
Science
, vol.285
, pp. 245-248
-
-
Dawson, D.W.1
Volpert, O.V.2
Gillis, P.3
Crawford, S.E.4
Xu, H.5
-
34
-
-
77958045673
-
RBPJkappa-dependent signaling is essential for long-term maintenance of neural stem cells in the adult hippocampus
-
Ehm O, Goritz C, Covic M, Schaffner I, Schwarz TJ, et al. RBPJkappa-dependent signaling is essential for long-term maintenance of neural stem cells in the adult hippocampus. J Neurosci. 2010; 30: 13794–13807. doi: 10.1523/JNEUROSCI.1567-10.2010 20943920
-
(2010)
J Neurosci
, vol.30
, pp. 13794-13807
-
-
Ehm, O.1
Goritz, C.2
Covic, M.3
Schaffner, I.4
Schwarz, T.J.5
-
35
-
-
37149031062
-
CBF-1 promotes transcriptional silencing during the establishment of HIV-1 latency
-
Tyagi M, Karn J, CBF-1 promotes transcriptional silencing during the establishment of HIV-1 latency. EMBO J. 2007; 26: 4985–4995. 18007589
-
(2007)
EMBO J
, vol.26
, pp. 4985-4995
-
-
Tyagi, M.1
Karn, J.2
-
36
-
-
67449101292
-
Laminin receptor involvement in the anti-angiogenic activity of pigment epithelium-derived factor
-
Bernard A, Gao-Li J, Franco CA, Bouceba T, Huet A, et al. Laminin receptor involvement in the anti-angiogenic activity of pigment epithelium-derived factor. J Biol Chem. 2009; 284: 10480–10490. doi: 10.1074/jbc.M809259200 19224861
-
(2009)
J Biol Chem
, vol.284
, pp. 10480-10490
-
-
Bernard, A.1
Gao-Li, J.2
Franco, C.A.3
Bouceba, T.4
Huet, A.5
-
37
-
-
79960341497
-
Identification of a novel inhibitor of the canonical Wnt pathway
-
Park K, Lee K, Zhang B, Zhou T, He X, et al. Identification of a novel inhibitor of the canonical Wnt pathway. Mol Cell Biol. 2011; 31: 3038–3051. doi: 10.1128/MCB.01211-10 21576363
-
(2011)
Mol Cell Biol
, vol.31
, pp. 3038-3051
-
-
Park, K.1
Lee, K.2
Zhang, B.3
Zhou, T.4
He, X.5
-
38
-
-
84990996913
-
Identification of PLXDC1 and PLXDC2 as the transmembrane receptors for the multifunctional factor PEDF
-
Cheng G, Zhong M, Kawaguchi R, Kassai M, Al-Ubaidi M, et al. Identification of PLXDC1 and PLXDC2 as the transmembrane receptors for the multifunctional factor PEDF. Elife. 2014; 3: e05401. doi: 10.7554/eLife.05401 25535841
-
(2014)
Elife
, vol.3
, pp. 5401
-
-
Cheng, G.1
Zhong, M.2
Kawaguchi, R.3
Kassai, M.4
Al-Ubaidi, M.5
-
39
-
-
67749110060
-
Splicing factors PTBP1 and PTBP2 promote proliferation and migration of glioma cell lines
-
Cheung HC, Hai T, Zhu W, Baggerly KA, Tsavachidis S, et al. Splicing factors PTBP1 and PTBP2 promote proliferation and migration of glioma cell lines. Brain. 2009; 132: 2277–2288. doi: 10.1093/brain/awp153 19506066
-
(2009)
Brain
, vol.132
, pp. 2277-2288
-
-
Cheung, H.C.1
Hai, T.2
Zhu, W.3
Baggerly, K.A.4
Tsavachidis, S.5
-
40
-
-
44849106532
-
Epidermal growth factor plays a crucial role in mitogenic regulation of human brain tumor stem cells
-
Soeda A, Inagaki A, Oka N, Ikegame Y, Aoki H, et al. Epidermal growth factor plays a crucial role in mitogenic regulation of human brain tumor stem cells. J Biol Chem. 2008; 283: 10958–10966. doi: 10.1074/jbc.M704205200 18292095
-
(2008)
J Biol Chem
, vol.283
, pp. 10958-10966
-
-
Soeda, A.1
Inagaki, A.2
Oka, N.3
Ikegame, Y.4
Aoki, H.5
-
41
-
-
0025313141
-
Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma
-
Humphrey PA, Wong AJ, Vogelstein B, Zalutsky MR, Fuller GN, et al. Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma. Proc Natl Acad Sci U S A. 1990; 87: 4207–4211. 1693434
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 4207-4211
-
-
Humphrey, P.A.1
Wong, A.J.2
Vogelstein, B.3
Zalutsky, M.R.4
Fuller, G.N.5
-
42
-
-
0026548240
-
Structural alterations of the epidermal growth factor receptor gene in human gliomas
-
Wong AJ, Ruppert JM, Bigner SH, Grzeschik CH, Humphrey PA, et al. Structural alterations of the epidermal growth factor receptor gene in human gliomas. Proc Natl Acad Sci U S A. 1992; 89: 2965–2969. 1557402
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 2965-2969
-
-
Wong, A.J.1
Ruppert, J.M.2
Bigner, S.H.3
Grzeschik, C.H.4
Humphrey, P.A.5
-
43
-
-
84886089551
-
The epidermal growth factor receptor variant III (EGFRvIII): where wild things are altered
-
Gan HK, Cvrljevic AN, Johns TG, The epidermal growth factor receptor variant III (EGFRvIII): where wild things are altered. FEBS J. 2013; 280: 5350–5370. doi: 10.1111/febs.12393 23777544
-
(2013)
FEBS J
, vol.280
, pp. 5350-5370
-
-
Gan, H.K.1
Cvrljevic, A.N.2
Johns, T.G.3
-
44
-
-
77955911497
-
Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma
-
Inda MM, Bonavia R, Mukasa A, Narita Y, Sah DW, et al. Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma. Genes Dev. 2010; 24: 1731–1745. doi: 10.1101/gad.1890510 20713517
-
(2010)
Genes Dev
, vol.24
, pp. 1731-1745
-
-
Inda, M.M.1
Bonavia, R.2
Mukasa, A.3
Narita, Y.4
Sah, D.W.5
-
45
-
-
8744234208
-
Immunohistochemical analysis of the mutant epidermal growth factor, deltaEGFR, in glioblastoma
-
Nishikawa R, Sugiyama T, Narita Y, Furnari F, Cavenee WK, et al. Immunohistochemical analysis of the mutant epidermal growth factor, deltaEGFR, in glioblastoma. Brain Tumor Pathol. 2004; 21: 53–56. 15700833
-
(2004)
Brain Tumor Pathol
, vol.21
, pp. 53-56
-
-
Nishikawa, R.1
Sugiyama, T.2
Narita, Y.3
Furnari, F.4
Cavenee, W.K.5
-
46
-
-
84879011160
-
A minority subpopulation of CD133(+) /EGFRvIII(+) /EGFR(-) cells acquires stemness and contributes to gefitinib resistance
-
Liu XJ, Wu WT, Wu WH, Yin F, Ma SH, et al. A minority subpopulation of CD133(+) /EGFRvIII(+) /EGFR(-) cells acquires stemness and contributes to gefitinib resistance. CNS Neurosci Ther. 2013; 19: 494–502. doi: 10.1111/cns.12092 23575351
-
(2013)
CNS Neurosci Ther
, vol.19
, pp. 494-502
-
-
Liu, X.J.1
Wu, W.T.2
Wu, W.H.3
Yin, F.4
Ma, S.H.5
-
47
-
-
78149254368
-
Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma
-
Sampson JH, Heimberger AB, Archer GE, Aldape KD, Friedman AH, et al. Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma. J Clin Oncol. 2013; 28: 4722–4729.
-
(2013)
J Clin Oncol
, vol.28
, pp. 4722-4729
-
-
Sampson, J.H.1
Heimberger, A.B.2
Archer, G.E.3
Aldape, K.D.4
Friedman, A.H.5
-
48
-
-
33846029123
-
A perivascular niche for brain tumor stem cells
-
Calabrese C, Poppleton H, Kocak M, Hogg TL, Fuller C, et al. A perivascular niche for brain tumor stem cells. Cancer Cell. 2007; 11: 69–82. 17222791
-
(2007)
Cancer Cell
, vol.11
, pp. 69-82
-
-
Calabrese, C.1
Poppleton, H.2
Kocak, M.3
Hogg, T.L.4
Fuller, C.5
-
49
-
-
65749106405
-
Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells
-
Li Z, Bao S, Wu Q, Wang H, Eyler C, et al. Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells. Cancer Cell. 2009: 15: 501–513. doi: 10.1016/j.ccr.2009.03.018 19477429
-
(2009)
Cancer Cell
, vol.15
, pp. 501-513
-
-
Li, Z.1
Bao, S.2
Wu, Q.3
Wang, H.4
Eyler, C.5
-
50
-
-
77950838848
-
A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alpha
-
Seidel S, Garvalov BK, Wirta V, von Stechow L, Schanzer A, et al. A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alpha. Brain. 2010; 133: 983–995. doi: 10.1093/brain/awq042 20375133
-
(2010)
Brain
, vol.133
, pp. 983-995
-
-
Seidel, S.1
Garvalov, B.K.2
Wirta, V.3
von Stechow, L.4
Schanzer, A.5
-
51
-
-
39149144034
-
Stem cells and niches: mechanisms that promote stem cell maintenance throughout life
-
Morrison SJ, Spradling AC, Stem cells and niches: mechanisms that promote stem cell maintenance throughout life. Cell. 2008; 132: 598–611. doi: 10.1016/j.cell.2008.01.038 18295578
-
(2008)
Cell
, vol.132
, pp. 598-611
-
-
Morrison, S.J.1
Spradling, A.C.2
-
52
-
-
33748423422
-
Breaking out of the mold: diversity within adult stem cells and their niches
-
Nystul TG, Spradling AC, Breaking out of the mold: diversity within adult stem cells and their niches. Curr Opin Genet Dev. 2006; 16: 463–468. 16919446
-
(2006)
Curr Opin Genet Dev
, vol.16
, pp. 463-468
-
-
Nystul, T.G.1
Spradling, A.C.2
-
53
-
-
0034712109
-
Out of Eden: stem cells and their niches
-
Watt FM, Hogan BL, Out of Eden: stem cells and their niches. Science. 2000; 287: 1427–1430. 10688781
-
(2000)
Science
, vol.287
, pp. 1427-1430
-
-
Watt, F.M.1
Hogan, B.L.2
-
54
-
-
0141785164
-
A niche for adult neural stem cells
-
Doetsch F, A niche for adult neural stem cells. Curr Opin Genet Dev. 2003; 13: 543–550. 14550422
-
(2003)
Curr Opin Genet Dev
, vol.13
, pp. 543-550
-
-
Doetsch, F.1
-
55
-
-
0037106157
-
Hippocampal adult neurogenesis occurs in a microenvironment provided by PSA-NCAM-expressing immature neurons
-
Seki T, Hippocampal adult neurogenesis occurs in a microenvironment provided by PSA-NCAM-expressing immature neurons. J Neurosci Res. 2002; 69: 772–783. 12205671
-
(2002)
J Neurosci Res
, vol.69
, pp. 772-783
-
-
Seki, T.1
-
56
-
-
33747076381
-
Origin of oligodendrocytes in the subventricular zone of the adult brain
-
Menn B, Garcia-Verdugo JM, Yaschine C, Gonzalez-Perez O, Rowitch D, et al. Origin of oligodendrocytes in the subventricular zone of the adult brain. J Neurosci. 2006; 26: 7907–7918. 16870736
-
(2006)
J Neurosci
, vol.26
, pp. 7907-7918
-
-
Menn, B.1
Garcia-Verdugo, J.M.2
Yaschine, C.3
Gonzalez-Perez, O.4
Rowitch, D.5
-
57
-
-
65049088695
-
Cell migration in the normal and pathological postnatal mammalian brain
-
Cayre M, Canoll P, Goldman JE, Cell migration in the normal and pathological postnatal mammalian brain. Prog Neurobiol. 2009; 88: 41–63. doi: 10.1016/j.pneurobio.2009.02.001 19428961
-
(2009)
Prog Neurobiol
, vol.88
, pp. 41-63
-
-
Cayre, M.1
Canoll, P.2
Goldman, J.E.3
-
58
-
-
0027446940
-
Pigment epithelium-derived factor: neurotrophic activity and identification as a member of the serine protease inhibitor gene family
-
Steele FR, Chader GJ, Johnson LV, Tombran-Tink J, Pigment epithelium-derived factor: neurotrophic activity and identification as a member of the serine protease inhibitor gene family. Proc Natl Acad Sci U S A. 1993; 90: 1526–1530. 8434014
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 1526-1530
-
-
Steele, F.R.1
Chader, G.J.2
Johnson, L.V.3
Tombran-Tink, J.4
-
59
-
-
0025772716
-
PEDF: a pigment epithelium-derived factor with potent neuronal differentiative activity
-
Tombran-Tink J, Chader GG, Johnson LV, PEDF: a pigment epithelium-derived factor with potent neuronal differentiative activity. Exp Eye Res. 1991; 53: 411–414. 1936177
-
(1991)
Exp Eye Res
, vol.53
, pp. 411-414
-
-
Tombran-Tink, J.1
Chader, G.G.2
Johnson, L.V.3
-
60
-
-
33745204424
-
Pigment epithelium-derived factor inhibits oxidative stress-induced cell death by activation of extracellular signal-regulated kinases in cultured retinal pigment epithelial cells
-
Tsao YP, Ho TC, Chen SL, Cheng HC, Pigment epithelium-derived factor inhibits oxidative stress-induced cell death by activation of extracellular signal-regulated kinases in cultured retinal pigment epithelial cells. Life Sci. 2006; 79: 545–550. 16504212
-
(2006)
Life Sci
, vol.79
, pp. 545-550
-
-
Tsao, Y.P.1
Ho, T.C.2
Chen, S.L.3
Cheng, H.C.4
-
61
-
-
25444433324
-
Pigment epithelium-derived factor induces the production of chemokines by rat microglia
-
Takanohashi A, Yabe T, Schwartz JP, Pigment epithelium-derived factor induces the production of chemokines by rat microglia. Glia. 2005; 51: 266–278. 15816038
-
(2005)
Glia
, vol.51
, pp. 266-278
-
-
Takanohashi, A.1
Yabe, T.2
Schwartz, J.P.3
-
62
-
-
84875463812
-
The effects of PEDF on cancer biology: mechanisms of action and therapeutic potential
-
Becerra SP, Notario V, The effects of PEDF on cancer biology: mechanisms of action and therapeutic potential. Nat Rev Cancer. 2013; 13: 258–271. doi: 10.1038/nrc3484 23486238
-
(2013)
Nat Rev Cancer
, vol.13
, pp. 258-271
-
-
Becerra, S.P.1
Notario, V.2
-
63
-
-
0036304110
-
The role of notch in promoting glial and neural stem cell fates
-
Gaiano N, Fishell G, The role of notch in promoting glial and neural stem cell fates. Annu Rev Neurosci. 2002; 25: 471–490. 12052917
-
(2002)
Annu Rev Neurosci
, vol.25
, pp. 471-490
-
-
Gaiano, N.1
Fishell, G.2
-
64
-
-
33747874155
-
Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors
-
Fan X, Matsui W, Khaki L, Stearns D, Chun J, et al. Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors. Cancer Res. 2006; 66: 7445–7452. 16885340
-
(2006)
Cancer Res
, vol.66
, pp. 7445-7452
-
-
Fan, X.1
Matsui, W.2
Khaki, L.3
Stearns, D.4
Chun, J.5
-
65
-
-
36949031706
-
Notch activation promotes cell proliferation and the formation of neural stem cell-like colonies in human glioma cells
-
Zhang XP, Zheng G, Zou L, Liu HL, Hou LH, et al. Notch activation promotes cell proliferation and the formation of neural stem cell-like colonies in human glioma cells. Mol Cell Biochem. 2008; 307: 101–108. 17849174
-
(2008)
Mol Cell Biochem
, vol.307
, pp. 101-108
-
-
Zhang, X.P.1
Zheng, G.2
Zou, L.3
Liu, H.L.4
Hou, L.H.5
-
66
-
-
75349105363
-
NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts
-
Fan X, Khaki L, Zhu TS, Soules ME, Talsma CE, et al. NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts. Stem Cells. 2010; 28: 5–16. doi: 10.1002/stem.254 19904829
-
(2010)
Stem Cells
, vol.28
, pp. 5-16
-
-
Fan, X.1
Khaki, L.2
Zhu, T.S.3
Soules, M.E.4
Talsma, C.E.5
-
67
-
-
75349108271
-
Notch promotes radioresistance of glioma stem cells
-
Wang J, Wakeman TP, Lathia JD, Hjelmeland AB, Wang XF, et al. Notch promotes radioresistance of glioma stem cells. Stem Cells. 2010; 28: 17–28. doi: 10.1002/stem.261 19921751
-
(2010)
Stem Cells
, vol.28
, pp. 17-28
-
-
Wang, J.1
Wakeman, T.P.2
Lathia, J.D.3
Hjelmeland, A.B.4
Wang, X.F.5
-
68
-
-
84899524502
-
Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells
-
Suva ML, Rheinbay E, Gillespie SM, Patel AP, Wakimoto H, et al. Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells. Cell. 2014; 157: 580–594. doi: 10.1016/j.cell.2014.02.030 24726434
-
(2014)
Cell
, vol.157
, pp. 580-594
-
-
Suva, M.L.1
Rheinbay, E.2
Gillespie, S.M.3
Patel, A.P.4
Wakimoto, H.5
-
69
-
-
62449252775
-
Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis
-
Zhu H, Acquaviva J, Ramachandran P, Boskovitz A, Woolfenden S, et al. Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis. Proc Natl Acad Sci U S A. 2009; 106: 2712–2716. doi: 10.1073/pnas.0813314106 19196966
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 2712-2716
-
-
Zhu, H.1
Acquaviva, J.2
Ramachandran, P.3
Boskovitz, A.4
Woolfenden, S.5
-
70
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, et al. Identification of human brain tumour initiating cells. Nature. 2004; 432: 396–401. 15549107
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
Squire, J.A.4
Bayani, J.5
-
71
-
-
56249114865
-
Gene silencing for epidermal growth factor receptor variant III induces cell-specific cytotoxicity
-
Yamoutpour F, Bodempudi V, Park SE, Pan W, Mauzy MJ, et al. Gene silencing for epidermal growth factor receptor variant III induces cell-specific cytotoxicity. Mol Cancer Ther. 2008; 7: 3586–3597. doi: 10.1158/1535-7163.MCT-08-0653 19001441
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 3586-3597
-
-
Yamoutpour, F.1
Bodempudi, V.2
Park, S.E.3
Pan, W.4
Mauzy, M.J.5
|