Nimbolide Inhibits Nuclear Factor-КB Pathway in Intestinal Epithelial Cells and Macrophages and Alleviates Experimental Colitis in Mice

Phytotherapy Research

Volumn 30, Issue 10, 2016, Pages 1605-1614

  Seo, Ji Yeon ^a   Lee, Changhyun ^a   Hwang, Sung Wook ^b   Chun, Jaeyoung ^b   Im, Jong Pil ^b   Kim, Joo Sung ^a,b  

^a Seoul National University Hospital Healthcare System Gangnam Center   (South Korea)

^b Seoul National University College of Medicine   (South Korea)

Author keywords

macrophage; murine colitis; NF B; nimbolide

Indexed keywords

I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; NIMBOLIDE; TUMOR NECROSIS FACTOR; LIMONOID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BINDING AFFINITY; COLITIS; COLO 205 CELL LINE; COLON SHORTENING; CONTROLLED STUDY; DISEASE ACTIVITY INDEX SCORE; DNA BINDING; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VIVO STUDY; INTESTINE EPITHELIUM CELL; INTESTINE PARAMETERS; MACROPHAGE; MALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAW 264.7 CELL LINE; SCORING SYSTEM; SIGNAL TRANSDUCTION; WEIGHT REDUCTION; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED; CHEMISTRY; DRUG EFFECTS; EPITHELIUM CELL; HERBAL MEDICINE; INFLAMMATORY BOWEL DISEASES; METABOLISM; PATHOLOGY; PROCEDURES;

ANIMALS; COLITIS; EPITHELIAL CELLS; HERBAL MEDICINE; INFLAMMATORY BOWEL DISEASES; LIMONINS; MACROPHAGES; MICE; MICE, INBRED C57BL; NF-KAPPA B;

EID: 84973569805     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.5657     Document Type: Article

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