Induction of apoptosis in human breast cancer cells by nimbolide through extrinsic and intrinsic pathway

Toxicology Letters

Volumn 215, Issue 2, 2012, Pages 131-142

  Elumalai, P ^a   Gunadharini, D N ^a   Senthilkumar, K ^a   Banudevi, S ^a   Arunkumar, R ^a   Benson, C S ^a   Sharmila, G ^a   Arunakaran, J ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

Apoptosis; Breast cancer cell lines; Intrinsic and extrinsic; Nimbolide

Indexed keywords

CASPASE; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; ESTROGEN RECEPTOR ALPHA; FAS LIGAND; NIMBOLIDE; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN MCL 1; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; X LINKED INHIBITOR OF APOPTOSIS;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CYTOTOXICITY; DRUG MECHANISM; FLOWER; GROWTH INHIBITION; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; NUCLEOTIDE SEQUENCE; PLANT LEAF; PRIORITY JOURNAL; PROTEIN CLEAVAGE; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-ASSOCIATED DEATH PROTEIN; BREAST NEOPLASMS; CASPASES; CELL SURVIVAL; CYTOCHROMES C; FAS LIGAND PROTEIN; FEMALE; HUMANS; LIMONINS; MCF-7 CELLS; MEMBRANE POTENTIAL, MITOCHONDRIAL; NEOPLASMS, HORMONE-DEPENDENT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

AZADIRACHTA INDICA;

EID: 84868332752     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2012.10.008     Document Type: Article

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