Aeroallergen-induced IL-33 predisposes to respiratory virus–induced asthma by dampening antiviral immunity

Journal of Allergy and Clinical Immunology

Volumn 138, Issue 5, 2016, Pages 1326-1337

  Lynch, Jason P ^a   Werder, Rhiannon B ^a   Simpson, Jennifer ^a   Loh, Zhixuan ^a   Zhang, Vivian ^a   Haque, Ashraful ^b   Spann, Kirsten ^a,c   Sly, Peter D ^a   Mazzone, Stuart B ^a   Upham, John W ^a   Phipps, Simon ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^c QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

Author keywords

antiviral; IL 33; interferon; plasmacytoid dendritic cell; Pneumonia virus of mice; respiratory syncytial virus; type 2 innate lymphoid cell

Indexed keywords

ALLERGEN; ALPHA INTERFERON; APYRASE; INTERFERON REGULATORY FACTOR 7; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 33; TOLL LIKE RECEPTOR 7; AIR POLLUTANT; CYTOKINE; INSECT PROTEIN;

AIRWAY REMODELING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL PRODUCT; ANTIVIRAL ACTIVITY; ARTICLE; ASTHMA; BRONCHIOLITIS; COCKROACH; COCKROACH EXTRACT; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE SEVERITY; DOWN REGULATION; FLOW CYTOMETRY; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INNATE IMMUNITY; INTERFERON PRODUCTION; LUNG PARENCHYMA; MOUSE; MUSCLE GROWTH; NONHUMAN; PLASMACYTOID DENDRITIC CELL; PNEUMOVIRUS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RISK FACTOR; SMOOTH MUSCLE; STUDY; VIRAL RESPIRATORY TRACT INFECTION; VIRUS LOAD; AIR POLLUTANT; ANIMAL; BAGG ALBINO MOUSE; BRONCHOALVEOLAR LAVAGE FLUID; DENDRITIC CELL; IMMUNOLOGY; LUNG; MURINE PNEUMONIA VIRUS; PNEUMOVIRUS INFECTION; VIROLOGY;

AIR POLLUTANTS; ALLERGENS; ANIMALS; ASTHMA; BRONCHOALVEOLAR LAVAGE FLUID; COCKROACHES; CYTOKINES; DENDRITIC CELLS; INSECT PROTEINS; LUNG; MICE, INBRED BALB C; MURINE PNEUMONIA VIRUS; PNEUMOVIRUS INFECTIONS; VIRAL LOAD;

EID: 84973444977     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2016.02.039     Document Type: Article

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