Toward improved prediction of risk for atopy and asthma among preschoolers: A prospective cohort study

Journal of Allergy and Clinical Immunology

Volumn 125, Issue 3, 2010, Pages

  Holt, Patrick G ^a   Rowe, Julie ^a   Kusel, Merci ^a   Parsons, Faith ^a   Hollams, Elysia M ^a   Bosco, Anthony ^a   McKenna, Kathy ^a   Subrata, Lily ^a   de Klerk, Nicholas ^a   Serralha, Michael ^a   Holt, Barbara J ^a   Zhang, Guicheng ^b   Loh, Richard ^c   Ahlstedt, Staffan ^d,e   Sly, Peter D ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c PRINCESS MARGARET HOSPITAL FOR CHILDREN   (Australia)

^d Thermo Fisher Scientific   (United States)

^e KAROLINSKA INSTITUTE   (Sweden)

Author keywords

asthma; IgE; infancy; respiratory tract infection; wheeze

Indexed keywords

BIOLOGICAL MARKER; IMMUNOGLOBULIN E; INTERLEUKIN 4 RECEPTOR;

ALLERGIC ASTHMA; ANTIBODY PRODUCTION; ANTIBODY TITER; ARTICLE; ATOPY; CELLULAR IMMUNITY; CHILD; CLINICAL ASSESSMENT; CONTROLLED STUDY; DISEASE SEVERITY; FAMILY HISTORY; FEMALE; FOLLOW UP; HUMAN; IMMUNOLOGICAL PROCEDURES; INFANCY; LABORATORY TEST; LOWER RESPIRATORY TRACT; MAJOR CLINICAL STUDY; MALE; MEMORY T LYMPHOCYTE; PREDICTIVE VALIDITY; PRESCHOOL CHILD; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN EXPRESSION; RESPIRATORY TRACT DISEASE; SENSITIZATION; TH2 CELL; WHEEZING;

EID: 77649248142     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2009.12.018     Document Type: Article

References (31)

1. Sly P.D., Boner A.L., Bjorksten B., Bush A., Custovic A., Eigenmann P.A., et al. Early identification of atopy in the prediction of the development of persistent asthma in children. Lancet 372 (2008) 1100-1106
2. Illi S., von Mutius E., Lau S., Niggemann B., Gruber C., and Wahn U. Perennial allergen sensitisation early in life and chronic asthma in children: a birth cohort study. Lancet 368 (2006) 763-770
3. Kusel M.M.H., de Klerk N.H., Kebadze T., Vohma V., Holt P.G., Johnston S.L., et al. Early-life respiratory viral infections, atopic sensitization and risk of subsequent development of persistent asthma. J Allergy Clin Immunol 119 (2007) 1105-1110
4. Rhodes H.L., Thomas P., Sporik R., Holgate S.T., and Cogswell J.J. A birth cohort study of subjects at risk of atopy: twenty-two-year follow-up of wheeze and atopic status. Am J Respir Crit Care Med 165 (2002) 176-180
5. Sherrill D., Stein R., Kurzius-Spencer M., and Martinez F. Early sensitization to allergens and development of respiratory symptoms. Clin Exp Allergy 29 (1999) 905-911
6. Oddy W.H., de Klerk N.H., Sly P.D., and Holt P.G. The effects of respiratory infections, atopy, and breastfeeding on childhood asthma. Eur Respir J 19 (2002) 899-905
7. Holt P.G., Upham J.W., and Sly P.D. Contemporaneous maturation of immunologic and respiratory functions during early childhood: implications for development of asthma prevention strategies. J Allergy Clin Immunol 116 (2005) 16-24
8. Holt P.G., and Sly P.D. Prevention of allergic respiratory disease in infants: current aspects and future perspectives. Curr Opin Allergy Clin Immunol 7 (2007) 547-555
9. Kusel M.M., de Klerk N.H., Holt P.G., Kebadze T., Johnston S.L., and Sly P.D. Role of respiratory viruses in acute upper and lower respiratory tract illness in the first year of life: a birth cohort study. Pediatr Infect Dis J 25 (2006) 680-686
10. Zhang G., Rowe J., Kusel M., Bosco A., McKenna K., de Klerk N., et al. Interleukin-10/interleukin-5 responses at birth predict risk for respiratory infections in children with atopic family history. Am J Respir Crit Care Med 179 (2009) 205-211
11. Rowe J., Kusel M., Holt B.J., Suriyaarachchi D., Serralha M., Hollams E., et al. Prenatal versus postnatal sensitization to environmental allergens in a high-risk birth cohort. J Allergy Clin Immunol 119 (2007) 1164-1173
12. Bosco A., McKenna K.L., Firth M.J., Sly P.D., and Holt P.G. A network modeling approach to analysis of the Th2 memory responses underlying human atopic disease. J Immunol 182 (2009) 6011-6021
13. Holt P.G., and McMenamin C. Defence against allergic sensitization in the healthy lung: the role of inhalation tolerance. Clin Exp Allergy 19 (1989) 255-262
14. Hattevig G., Kjellman B., and Björkstén B. Appearance IgE antibodies to ingested and inhaled allergens during the first 12 years of life in atopic and non-atopic children. Pediatr Allergy Immunol 4 (1993) 182-186
15. Holt P.G., O'Keeffe P., Holt B.J., Upham J.W., Baron-Hay M.J., Suphiolglu C., et al. T-cell "priming" against environmental allergens in human neonates; sequential deletion of food allergen reactivity during infancy with concomitant expansion of responses to ubiquitous inhalant allergens. Pediatric Allergy Immunol 6 (1995) 85-90
16. Mariani F., Price J.F., and Kemeny D.M. The IgG subclass antibody response to an inhalant antigen (Dermatophagoides pteronyssinus) during the first year of life: evidence for early stimulation of the immune system following natural exposure. Clin Exp Allergy 22 (1992) 29-33
17. Prescott S.L., Macaubas C., Smallacombe T., Holt B.J., Sly P.D., and Holt P.G. Development of allergen-specific T-cell memory in atopic and normal children. Lancet 353 (1999) 196-200
18. Mosmann T.R., and Coffman R.L. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 7 (1989) 145-173
19. Heaton T., Rowe J., Turner S., Aalberse R.C., de Klerk N., Suriyaarachchi D., et al. An immunoepidemiological approach to asthma: identification of in-vitro T-cell response patterns associated with different wheezing phenotypes in children. Lancet 365 (2005) 142-149
20. Holt P.G., Rudin A., Macaubas C., Holt B.J., Rowe J., Loh R., et al. Development of immunologic memory against tetanus toxoid and pertactin antigens from the diphtheria-tetanus-pertussis vaccine in atopic versus nonatopic children. J Allergy Clin Immunol 105 (2000) 1117-1122
21. Smart J.M., and Kemp A.S. Increased Th1 and Th2 allergen-induced cytokine responses in children with atopic disease. Clin Exp Allergy 32 (2002) 796-802
22. Calhoun W.J., Murphy K., Stevens C.A., Jarjour N.N., and Busse W.W. Increased interferon-γ and tumor necrosis factor-α in bronchoalveolar lavage (BAL) fluid after antigen challenge in allergic subjects. Am Rev Respir Dis 145 (1992) A638
23. Magnan A.O., Mely L.G., Camilla C.A., Badier M.M., Montero-Julian F.A., Guillot C.M., et al. Assessment of the Th1/Th2 paradigm in whole blood in atopy and asthma. Increased IFN-gamma-producing CD8(+) T cells in asthma. Am J Respir Crit Care Med 161 (2000) 1790-1796
24. O'Garra A., and Arai N. The molecular basis of T helper 1 and T helper 2 cell differentiation. Trends Cell Biol 10 (2000) 542-550
25. Liao W., Schones D.E., Oh J., Cui Y., Cui K., Roh T.Y., et al. Priming for T helper type 2 differentiation by interleukin 2-mediated induction of interleukin 4 receptor alpha-chain expression. Nat Immunol 9 (2008) 1288-1296
26. Geha R.S., Jabara H.H., and Brodeur S.R. The regulation of immunoglobulin E class-switch recombination. Nat Rev Immunol 3 (2003) 721-732
27. Gavin M.A., and Bevan M.J. Increased peptide promiscuity provides a rationale for the lack of N regions in the neonatal T cell repertoire. Immunity 3 (1995) 793-800
28. Hassan J., and Reen D.J. Human recent thymic emigrants-identification, expansion and survival characteristics. J Immunol 167 (2001) 1970-1976
29. Thornton C.A., Upham J.W., Wikstrom M.E., Holt B.J., White G.P., Sharp M.J., et al. Functional maturation of CD4(+)CD25(+)CTLA4(+)CD45RA(+) T regulatory cells in human neonatal T cell responses to environmental antigens/allergens. J Immunol 173 (2004) 3084-3092
30. Hayward A.R., and Groothuis J. Development of T cells with memory phenotype in infancy. Adv Exp Med Biol 310 (1991) 71-76
31. Rowe J., Macaubas C., Monger T., Holt B.J., Harvey J., Poolman J.T., et al. Heterogeneity in diphtheria-tetanus-acellular pertussis vaccine-specific cellular immunity during infancy: relationship to variations in the kinetics of postnatal maturation of systemic Th1 function. J Infect Dis 184 (2001) 80-88