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Volumn 7, Issue 1, 2015, Pages

In vivo molecular neuroimaging of glucose utilization and its association with fibrillar amyloid-â load in aged APPPS1-21 mice

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AV45 F 18; FLUORODEOXYGLUCOSE F 18; PIB C 11; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; AMYLOID; AMYLOID PRECURSOR PROTEIN; ANILINE DERIVATIVE; APP PROTEIN, HUMAN; CARBON; DIETHYL-1,3,6,8-TETRAHYDRO-1,3,6,8-TETRAOXOBENZO(LMN)(3,8)PHENANTHROLINE-2,7-DIACETATE; ETHYLENE GLYCOL DERIVATIVE; FLORBETAPIR; GLUCOSE; PHENANTHROLINE DERIVATIVE;

EID: 84973407800     PISSN: None     EISSN: 17589193     Source Type: Journal    
DOI: 10.1186/s13195-015-0158-6     Document Type: Article
Times cited : (28)

References (59)
  • 1
    • 17844364259 scopus 로고    scopus 로고
    • Brain glucose metabolism in the early and specific diagnosis of Alzheimer's disease. FDG-PET studies in MCI and AD
    • Mosconi L. Brain glucose metabolism in the early and specific diagnosis of Alzheimer's disease. FDG-PET studies in MCI and AD. Eur J Nucl Med Mol Imaging. 2005;32:486-510.
    • (2005) Eur J Nucl Med Mol Imaging , vol.32 , pp. 486-510
    • Mosconi, L.1
  • 2
    • 0036743220 scopus 로고    scopus 로고
    • Discrimination between Alzheimer dementia and controls by automated analysis of multicenter FDG PET
    • Herholz K, Salmon E, Perani D, Baron JC, Holthoff V, Frolich L, et al. Discrimination between Alzheimer dementia and controls by automated analysis of multicenter FDG PET. Neuro Image. 2002;17:302-16.
    • (2002) Neuro Image , vol.17 , pp. 302-316
    • Herholz, K.1    Salmon, E.2    Perani, D.3    Baron, J.C.4    Holthoff, V.5    Frolich, L.6
  • 3
    • 0033927770 scopus 로고    scopus 로고
    • Longitudinal evaluation of early Alzheimer's disease using brain perfusion SPECT
    • Kogure D, Matsuda H, Ohnishi T, Asada T, Uno M, Kunihiro T, et al. Longitudinal evaluation of early Alzheimer's disease using brain perfusion SPECT. J Nucl Med. 2000;41:1155-62.
    • (2000) J Nucl Med. , vol.41 , pp. 1155-1162
    • Kogure, D.1    Matsuda, H.2    Ohnishi, T.3    Asada, T.4    Uno, M.5    Kunihiro, T.6
  • 4
    • 56349144614 scopus 로고    scopus 로고
    • Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study
    • Edison P, Archer HA, Gerhard A, Hinz R, Pavese N, Turkheimer FE, et al. Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study. Neurobiol Dis. 2008;32:412-9.
    • (2008) Neurobiol Dis. , vol.32 , pp. 412-419
    • Edison, P.1    Archer, H.A.2    Gerhard, A.3    Hinz, R.4    Pavese, N.5    Turkheimer, F.E.6
  • 5
    • 63849193695 scopus 로고    scopus 로고
    • Microglial activation and amyloid deposition in mild cognitive impairment: A PET study
    • Okello A, Edison P, Archer HA, Turkheimer FE, Kennedy J, Bullock R, et al. Microglial activation and amyloid deposition in mild cognitive impairment: a PET study. Neurology. 2009;72:56-62.
    • (2009) Neurology , vol.72 , pp. 56-62
    • Okello, A.1    Edison, P.2    Archer, H.A.3    Turkheimer, F.E.4    Kennedy, J.5    Bullock, R.6
  • 6
    • 10744232413 scopus 로고    scopus 로고
    • Imaging brain amyloid in Alzheimer's disease with pittsburgh compound-B
    • Klunk WE, Engler H, Nordberg A, Wang Y. Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B. Ann Neurol. 2004;55:306-19.
    • (2004) Ann Neurol. , vol.55 , pp. 306-319
    • Klunk, W.E.1    Engler, H.2    Nordberg, A.3    Wang, Y.4
  • 7
    • 84887416188 scopus 로고    scopus 로고
    • [18 F]T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease
    • Xia CF, Arteaga J, Chen G, Gangadharmath U, Gomez LF, Kasi D, et al. [18 F]T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease. Alzheimers Dement. 2013;9:666-76.
    • (2013) Alzheimers Dement. , vol.9 , pp. 666-676
    • Xia, C.F.1    Arteaga, J.2    Chen, G.3    Gangadharmath, U.4    Gomez, L.F.5    Kasi, D.6
  • 9
    • 45749151056 scopus 로고    scopus 로고
    • Animal models of Alzheimer's disease and frontotemporal dementia
    • Götz J, Ittner LM. Animal models of Alzheimer's disease and frontotemporal dementia. Nat Rev Neurosci. 2008;9:532-44.
    • (2008) Nat Rev Neurosci. , vol.9 , pp. 532-544
    • Götz, J.1    Ittner, L.M.2
  • 10
    • 27944471285 scopus 로고    scopus 로고
    • Binding of the positron emission tomography tracer pittsburgh compound-B reflects the amount of amyloid-beta in Alzheimer's disease brain but not in transgenic mouse brain
    • Klunk WE, Lopresti BJ, Ikonomovic MD, Lefterov IM, Koldamova RP, Abrahamson EE, et al. Binding of the positron emission tomography tracer Pittsburgh compound-B reflects the amount of amyloid-beta in Alzheimer's disease brain but not in transgenic mouse brain. J Neurosci. 2005;25:10598-606.
    • (2005) J Neurosci. , vol.25 , pp. 10598-10606
    • Klunk, W.E.1    Lopresti, B.J.2    Ikonomovic, M.D.3    Lefterov, I.M.4    Koldamova, R.P.5    Abrahamson, E.E.6
  • 11
    • 35348821915 scopus 로고    scopus 로고
    • Longitudinal, quantitative assessment of amyloid, neuroinflammation, and anti-amyloid treatment in a living mouse model of Alzheimer's disease enabled by positron emission tomography
    • Maeda J, Ji B, Irie T, Tomiyama T, Maruyama M, Okauchi T, et al. Longitudinal, quantitative assessment of amyloid, neuroinflammation, and anti-amyloid treatment in a living mouse model of Alzheimer's disease enabled by positron emission tomography. J Neurosci. 2007;27:10957-68.
    • (2007) J Neurosci. , vol.27 , pp. 10957-10968
    • Maeda, J.1    Ji, B.2    Irie, T.3    Tomiyama, T.4    Maruyama, M.5    Okauchi, T.6
  • 12
    • 84857959777 scopus 로고    scopus 로고
    • Small-animal PET imaging of amyloid-beta plaques with [11C] PiB and its multi-modal validation in an APP/PS1 mouse model of Alzheimer's disease
    • Manook A, Yousefi BH, Willuweit A, Platzer S, Reder S. Small-animal PET imaging of amyloid-beta plaques with [11C] PiB and its multi-modal validation in an APP/PS1 mouse model of Alzheimer's disease. PLoS One. 2012;7:e31310.
    • (2012) PLoS One , vol.7 , pp. e31310
    • Manook, A.1    Yousefi, B.H.2    Willuweit, A.3    Platzer, S.4    Reder, S.5
  • 13
    • 84879911625 scopus 로고    scopus 로고
    • Longitudinal assessment of cerebral β-amyloid deposition in mice overexpressing swedish mutant β-amyloid precursor protein using 18 F-florbetaben PET
    • Rominger A, Brendel M, Burgold S, Keppler K, Baumann K, Xiong G, et al. Longitudinal assessment of cerebral β-amyloid deposition in mice overexpressing Swedish mutant β-amyloid precursor protein using 18 F-florbetaben PET. J Nucl Med. 2013;54:1127-34.
    • (2013) J Nucl Med. , vol.54 , pp. 1127-1134
    • Rominger, A.1    Brendel, M.2    Burgold, S.3    Keppler, K.4    Baumann, K.5    Xiong, G.6
  • 14
    • 84881392145 scopus 로고    scopus 로고
    • Longitudinal amyloid imaging in mouse brain with 11C-PIB: Comparison of APP23, Tg2576, and APPswe-PS1dE9 mouse models of Alzheimer disease
    • Snellman A, Lopez-Picon FR, Rokka J, Salmona M, Forloni G, Scheinin M, et al. Longitudinal amyloid imaging in mouse brain with 11C-PIB: comparison of APP23, Tg2576, and APPswe-PS1dE9 mouse models of Alzheimer disease. J Nucl Med. 2013;54:1434-41.
    • (2013) J Nucl Med. , vol.54 , pp. 1434-1441
    • Snellman, A.1    Lopez-Picon, F.R.2    Rokka, J.3    Salmona, M.4    Forloni, G.5    Scheinin, M.6
  • 15
    • 84925581714 scopus 로고    scopus 로고
    • Longitudinal PET-MRI reveals β-amyloid deposition and rCBF dynamics and connects vascular amyloidosis to quantitative loss of perfusion
    • Maier FC, Wehrl HF, Schmid AM, Mannheim JG, Wiehr S, Lerdkrai C, et al. Longitudinal PET-MRI reveals β-amyloid deposition and rCBF dynamics and connects vascular amyloidosis to quantitative loss of perfusion. Nat Med. 2014;20:1485-92.
    • (2014) Nat Med. , vol.20 , pp. 1485-1492
    • Maier, F.C.1    Wehrl, H.F.2    Schmid, A.M.3    Mannheim, J.G.4    Wiehr, S.5    Lerdkrai, C.6
  • 16
    • 84865590071 scopus 로고    scopus 로고
    • PET imaging with [18 F]AV-45 in an APP/PS1-21 murine model of amyloid plaque deposition
    • Poisnel G, Dhilly M, Moustié O, Delamare J, Abbas A, Guilloteau D, et al. PET imaging with [18 F]AV-45 in an APP/PS1-21 murine model of amyloid plaque deposition. Neurobiol Aging. 2012;33:2561-71.
    • (2012) Neurobiol Aging , vol.33 , pp. 2561-2571
    • Poisnel, G.1    Dhilly, M.2    Moustié, O.3    Delamare, J.4    Abbas, A.5    Guilloteau, D.6
  • 17
    • 84937762685 scopus 로고    scopus 로고
    • Astrocytosis precedes amyloid plaque deposition in Alzheimer APPswe transgenic mouse brain: A correlative positron emission tomography and in vitro imaging study
    • Rodriguez-Vieitez E, Ni R, Gulyás B, Toth M, Häggkvist J, Halldin C, et al. Astrocytosis precedes amyloid plaque deposition in Alzheimer APPswe transgenic mouse brain: a correlative positron emission tomography and in vitro imaging study. Eur J Nucl Med Mol Imaging. 2015;42:1119-32.
    • (2015) Eur J Nucl Med Mol Imaging , vol.42 , pp. 1119-1132
    • Rodriguez-Vieitez, E.1    Ni, R.2    Gulyás, B.3    Toth, M.4    Häggkvist, J.5    Halldin, C.6
  • 18
    • 84942549558 scopus 로고    scopus 로고
    • Amyloid-PET predicts inhibition of de novo plaque formation upon chronic γ-secretase modulator treatment
    • Brendel M, Jaworska A, Herms J, Trambauer J, Rötzer C, Gildehaus FJ, et al. Amyloid-PET predicts inhibition of de novo plaque formation upon chronic γ-secretase modulator treatment. Mol Psychiatry. 2015;20:1179-87.
    • (2015) Mol Psychiatry , vol.20 , pp. 1179-1187
    • Brendel, M.1    Jaworska, A.2    Herms, J.3    Trambauer, J.4    Rötzer, C.5    Gildehaus, F.J.6
  • 19
    • 33749256422 scopus 로고    scopus 로고
    • Age- and transgene-related changes in regional cerebral metabolism in PSAPP mice
    • Valla J, Schneider L, Reiman EM. Age- and transgene-related changes in regional cerebral metabolism in PSAPP mice. Brain Res. 2006;1116:194-200.
    • (2006) Brain Res. , vol.1116 , pp. 194-200
    • Valla, J.1    Schneider, L.2    Reiman, E.M.3
  • 20
    • 41649097332 scopus 로고    scopus 로고
    • FDG autoradiography reveals developmental and pathological effects of mutant amyloid in PDAPP transgenic mice
    • Valla J, Gonzalez-Lima F, Reiman EM. FDG autoradiography reveals developmental and pathological effects of mutant amyloid in PDAPP transgenic mice. Int J Dev Biol. 2008;26:253-8.
    • (2008) Int J Dev Biol. , vol.26 , pp. 253-258
    • Valla, J.1    Gonzalez-Lima, F.2    Reiman, E.M.3
  • 21
  • 22
    • 0032735889 scopus 로고    scopus 로고
    • Early regional cerebral glucose hypometabolism in transgenic mice overexpressing the V717F-amyloid precursor protein
    • Dodart JC, Mathis C, Bales KR, Paul SM, Ungerer A. Early regional cerebral glucose hypometabolism in transgenic mice overexpressing the V717F-amyloid precursor protein. Neurosci Lett. 1999;277:49-52.
    • (1999) Neurosci Lett. , vol.277 , pp. 49-52
    • Dodart, J.C.1    Mathis, C.2    Bales, K.R.3    Paul, S.M.4    Ungerer, A.5
  • 23
    • 77951978741 scopus 로고    scopus 로고
    • Detection by voxel-wise statistical analysis of significant changes in regional cerebral glucose uptake in an APP/PS1 transgenic mouse model of Alzheimer's disease
    • Dubois A, Hérard AS, Delatour B, Hantraye P, Bonvento G, Dhenain M, et al. Detection by voxel-wise statistical analysis of significant changes in regional cerebral glucose uptake in an APP/PS1 transgenic mouse model of Alzheimer's disease. Neuro Image. 2010;51:586-98.
    • (2010) Neuro Image , vol.51 , pp. 586-598
    • Dubois, A.1    Hérard, A.S.2    Delatour, B.3    Hantraye, P.4    Bonvento, G.5    Dhenain, M.6
  • 24
    • 84868131284 scopus 로고    scopus 로고
    • Imaging microglial activation and glucose consumption in a mouse model of Alzheimer's disease
    • Rapic S, Backes H, Viel T, Kummer MP, Monfared P, Neumaier B, et al. Imaging microglial activation and glucose consumption in a mouse model of Alzheimer's disease. Neurobiol Aging. 2012;34:351-4.
    • (2012) Neurobiol Aging , vol.34 , pp. 351-354
    • Rapic, S.1    Backes, H.2    Viel, T.3    Kummer, M.P.4    Monfared, P.5    Neumaier, B.6
  • 25
    • 67649410208 scopus 로고    scopus 로고
    • Limitations of small animal PET imaging with [18 F]FDDNP and FDG for quantitative studies in a transgenic mouse model of Alzheimer's disease
    • Kuntner C, Kesner AL, Bauer M, Kremslehner R, Wanek T, Mandler M, et al. Limitations of small animal PET imaging with [18 F]FDDNP and FDG for quantitative studies in a transgenic mouse model of Alzheimer's disease. Mol Imaging Biol. 2009;11:236-40.
    • (2009) Mol Imaging Biol. , vol.11 , pp. 236-240
    • Kuntner, C.1    Kesner, A.L.2    Bauer, M.3    Kremslehner, R.4    Wanek, T.5    Mandler, M.6
  • 27
    • 84875821298 scopus 로고    scopus 로고
    • In vivo evaluation of amyloid deposition and brain glucose metabolism of 5XFAD mice using positron emission tomography
    • Rojas S, Herance JR, Gispert JD, Abad S, Torrent É, Jiménez X, et al. In vivo evaluation of amyloid deposition and brain glucose metabolism of 5XFAD mice using positron emission tomography. Neurobiol Aging. 2013;34:1790-8.
    • (2013) Neurobiol Aging , vol.34 , pp. 1790-1798
    • Rojas, S.1    Herance, J.R.2    Gispert, J.D.3    Abad, S.4    Torrent, É.5    Jiménez, X.6
  • 28
    • 84858332587 scopus 로고    scopus 로고
    • Characterization of 7- and 19-month-old Tg2576 mice using multimodal in vivo imaging: Limitations as a translatable model of Alzheimer's disease
    • Luo F, Rustay NR, Ebert U, Hradil VP, Cole TB, Llano DA, et al. Characterization of 7- and 19-month-old Tg2576 mice using multimodal in vivo imaging: limitations as a translatable model of Alzheimer's disease. Neurobiol Aging. 2012;33:933-44.
    • (2012) Neurobiol Aging , vol.33 , pp. 933-944
    • Luo, F.1    Rustay, N.R.2    Ebert, U.3    Hradil, V.P.4    Cole, T.B.5    Llano, D.A.6
  • 29
    • 0036338823 scopus 로고    scopus 로고
    • Effects of image resolution on autoradiographic measurements of posterior cingulate activity in PDAPP mice: Implications for functional brain imaging studies of transgenic mouse models of Alzheimer's disease
    • Valla J. Effects of image resolution on autoradiographic measurements of posterior cingulate activity in PDAPP mice: implications for functional brain imaging studies of transgenic mouse models of Alzheimer's disease. Neuro Image. 2002;16:1-6.
    • (2002) Neuro Image , vol.16 , pp. 1-6
    • Valla, J.1
  • 30
    • 84891702999 scopus 로고    scopus 로고
    • Mapping changes in mouse brain metabolism with PET/CT
    • Welch A, Mingarelli M, Riedel G, Platt B. Mapping changes in mouse brain metabolism with PET/CT. J Nucl Med. 2013;54:1946-53.
    • (2013) J Nucl Med. , vol.54 , pp. 1946-1953
    • Welch, A.1    Mingarelli, M.2    Riedel, G.3    Platt, B.4
  • 32
    • 84952650721 scopus 로고    scopus 로고
    • Investigations of brain glucose utilization in three transgenic mouse strains that develop neuropathological features of Alzheimer's disease
    • Kelley J, Wintmolders C, Bottelbergs A, Waldron AM, Wyffels L, Czech C, et al. Investigations of brain glucose utilization in three transgenic mouse strains that develop neuropathological features of Alzheimer's disease. Alzheimer's Dement. 2013;9:P329.
    • (2013) Alzheimer's Dement. , vol.9 , pp. P329
    • Kelley, J.1    Wintmolders, C.2    Bottelbergs, A.3    Waldron, A.M.4    Wyffels, L.5    Czech, C.6
  • 33
    • 84952654623 scopus 로고    scopus 로고
    • Quantitative muPET imaging of cerebral glucose metabolism and amyloidosis in the TASTPM double transgenic mouse model of Alzheimer's disease
    • Waldron A, Wyffels L, Verhaeghe J, Bottelbergs A, Richardson J, Kelley J, et al. Quantitative muPET imaging of cerebral glucose metabolism and amyloidosis in the TASTPM double transgenic mouse model of Alzheimer's disease. Curr Alzheimer Res. 2015;12:694-703.
    • (2015) Curr Alzheimer Res. , vol.12 , pp. 694-703
    • Waldron, A.1    Wyffels, L.2    Verhaeghe, J.3    Bottelbergs, A.4    Richardson, J.5    Kelley, J.6
  • 35
    • 79151475030 scopus 로고    scopus 로고
    • Synaptic plasticity in the hippocampus of a APP/PS1 mouse model of Alzheimer's disease is impaired in old but not young mice
    • Gengler S, Hamilton A, Hölscher C. Synaptic plasticity in the hippocampus of a APP/PS1 mouse model of Alzheimer's disease is impaired in old but not young mice. PLoS One. 2010;5:e9764.
    • (2010) PLoS One , vol.5 , pp. e9764
    • Gengler, S.1    Hamilton, A.2    Hölscher, C.3
  • 36
    • 33748988258 scopus 로고    scopus 로고
    • Aβ42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology
    • Radde R, Bolmont T, Kaeser SA, Coomaraswamy J, Lindau D, Stoltze L, et al. Aβ42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology. EMBO Rep. 2006;7:940-6.
    • (2006) EMBO Rep. , vol.7 , pp. 940-946
    • Radde, R.1    Bolmont, T.2    Kaeser, S.A.3    Coomaraswamy, J.4    Lindau, D.5    Stoltze, L.6
  • 38
    • 84941997343 scopus 로고    scopus 로고
    • Preclinical comparison of the amyloid-β radioligands [(11)C]Pittsburgh compound B and] (18)F]florbetaben in aged APPPS1-21 and BRI1-42 mouse models of cerebral amyloidosis
    • Waldron AM, Verhaeghe J, Wyffels L, Schmidt M, Langlois X, Van der Linden A, et al. Preclinical comparison of the amyloid-β radioligands [(11)C]Pittsburgh compound B and] (18)F]florbetaben in aged APPPS1-21 and BRI1-42 mouse models of cerebral amyloidosis. Mol Imaging Biol. 2015;17:688-96. doi:10.1007/s11307-015-0833-9.
    • (2015) Mol Imaging Biol. , vol.17 , pp. 688-696
    • Waldron, A.M.1    Verhaeghe, J.2    Wyffels, L.3    Schmidt, M.4    Langlois, X.5    Van Der-Linden, A.6
  • 39
    • 77956412778 scopus 로고    scopus 로고
    • GMP-compliant automated synthesis of [(18)F]AV-45 (Florbetapir F 18) for imaging beta-amyloid plaques in human brain
    • Yao CH, Lin WL, Weng CC, Hsiao IT, Ting YS, Yen TC, et al. GMP-compliant automated synthesis of [(18)F]AV-45 (Florbetapir F 18) for imaging beta-amyloid plaques in human brain. Appl Radiat Isot. 2010;68:2293-7.
    • (2010) Appl Radiat Isot. , vol.68 , pp. 2293-2297
    • Yao, C.H.1    Lin, W.L.2    Weng, C.C.3    Hsiao, I.T.4    Ting, Y.S.5    Yen, T.C.6
  • 40
    • 0028700063 scopus 로고
    • Accelerated image reconstruction using ordered subsets of projection data
    • Hudson HM, Larkin RS. Accelerated image reconstruction using ordered subsets of projection data. IEEE Trans Med Imaging. 1993;13:601-9.
    • (1993) IEEE Trans Med Imaging , vol.13 , pp. 601-609
    • Hudson, H.M.1    Larkin, R.S.2
  • 42
    • 0034244929 scopus 로고    scopus 로고
    • New, faster, image-based scatter correction for 3D PET
    • Watson CC. New, faster, image-based scatter correction for 3D PET. IEEE Trans Nucl Sci. 2000;47:1587-94.
    • (2000) IEEE Trans Nucl Sci. , vol.47 , pp. 1587-1594
    • Watson, C.C.1
  • 43
    • 34548713439 scopus 로고    scopus 로고
    • A novel approach for imaging brain-behavior relationships in mice reveals unexpected metabolic patterns during seizures in the absence of tissue plasminogen activator
    • Mirrione MM, Schiffer WK, Fowler JS, Alexoff DL, Dewey SL, Tsirka SE. A novel approach for imaging brain-behavior relationships in mice reveals unexpected metabolic patterns during seizures in the absence of tissue plasminogen activator. Neuro Image. 2007;38:34-42.
    • (2007) Neuro Image , vol.38 , pp. 34-42
    • Mirrione, M.M.1    Schiffer, W.K.2    Fowler, J.S.3    Alexoff, D.L.4    Dewey, S.L.5    Tsirka, S.E.6
  • 45
    • 60149105534 scopus 로고    scopus 로고
    • "Absolute" or 'relative': Choosing the right outcome measure in neuroimaging
    • Gründer G. "Absolute" or 'relative': choosing the right outcome measure in neuroimaging. Neuro Image. 2009;45:258-9.
    • (2009) Neuro Image , vol.45 , pp. 258-259
    • Gründer, G.1
  • 46
    • 0346365557 scopus 로고    scopus 로고
    • Assessment of microPET performance in analyzing the rat brain under different types of anesthesia: Comparison between quantitative data obtained with microPET and ex vivo autoradiography
    • Matsumura A, Mizokawa S, Tanaka M, Wada Y, Nozaki S, Nakamura F, et al. Assessment of microPET performance in analyzing the rat brain under different types of anesthesia: comparison between quantitative data obtained with microPET and ex vivo autoradiography. Neuro Image. 2003;20:2040-50.
    • (2003) Neuro Image , vol.20 , pp. 2040-2050
    • Matsumura, A.1    Mizokawa, S.2    Tanaka, M.3    Wada, Y.4    Nozaki, S.5    Nakamura, F.6
  • 47
    • 84872023531 scopus 로고    scopus 로고
    • Amyloid-β imaging with pittsburgh compound B and florbetapir: Comparing radiotracers and quantification methods
    • Landau SM, Breault C, Joshi AD, Pontecorvo M, Mathis CA, Jagust WJ, et al. Amyloid-β imaging with Pittsburgh compound B and florbetapir: comparing radiotracers and quantification methods. J Nucl Med. 2012;54:70-7.
    • (2012) J Nucl Med. , vol.54 , pp. 70-77
    • Landau, S.M.1    Breault, C.2    Joshi, A.D.3    Pontecorvo, M.4    Mathis, C.A.5    Jagust, W.J.6
  • 48
    • 70350716476 scopus 로고    scopus 로고
    • Preclinical properties of 18 F-AV-45: A PET agent for abeta plaques in the brain
    • Choi SR, Golding G, Zhuang Z, Zhang W, Lim N, Hefti F, et al. Preclinical properties of 18 F-AV-45: a PET agent for Abeta plaques in the brain. J Nucl Med. 2009;50:1887-94.
    • (2009) J Nucl Med. , vol.50 , pp. 1887-1894
    • Choi, S.R.1    Golding, G.2    Zhuang, Z.3    Zhang, W.4    Lim, N.5    Hefti, F.6
  • 49
    • 84885709706 scopus 로고    scopus 로고
    • Impact of partial volume effect correction on cerebral β-amyloid imaging in APP-swe mice using [(18)F]-florbetaben PET
    • Brendel M, Delker A, Rötzer C, Böning G, Carlsen J, Cyran C, et al. Impact of partial volume effect correction on cerebral β-amyloid imaging in APP-Swe mice using [(18)F]-florbetaben PET. Neuro Image. 2014;84:843-53.
    • (2014) Neuro Image , vol.84 , pp. 843-853
    • Brendel, M.1    Delker, A.2    Rötzer, C.3    Böning, G.4    Carlsen, J.5    Cyran, C.6
  • 50
    • 79951568314 scopus 로고    scopus 로고
    • Automated detection of amyloid-β-related cortical and subcortical signal changes in a transgenic model of Alzheimer's disease using high-field MRI
    • Teipel SJ, Kaza E, Hadlich S, Bauer A, Brüning T, Plath AS, et al. Automated detection of amyloid-β-related cortical and subcortical signal changes in a transgenic model of Alzheimer's disease using high-field MRI. J Alzheimers Dis. 2011;23:221-37.
    • (2011) J Alzheimers Dis. , vol.23 , pp. 221-237
    • Teipel, S.J.1    Kaza, E.2    Hadlich, S.3    Bauer, A.4    Brüning, T.5    Plath, A.S.6
  • 51
    • 80053646630 scopus 로고    scopus 로고
    • Early onset amyloid lesions lead to severe neuritic abnormalities and local, but not global neuron loss in APPPS1 transgenic mice
    • e1-6
    • Rupp NJ, Wegenast-Braun BM, Radde R, Calhoun ME, Jucker M. Early onset amyloid lesions lead to severe neuritic abnormalities and local, but not global neuron loss in APPPS1 transgenic mice. Neurobiol Aging. 2011;32:2324. e1-6.
    • (2011) Neurobiol Aging , vol.32 , pp. 2324
    • Rupp, N.J.1    Wegenast-Braun, B.M.2    Radde, R.3    Calhoun, M.E.4    Jucker, M.5
  • 52
    • 84855369203 scopus 로고    scopus 로고
    • Evidence for astrocytosis in prodromal Alzheimer disease provided by 11Cdeuterium-L-deprenyl: A multitracer PET paradigm combining 11CPittsburgh compound B and 18 F-FDG
    • Carter SF, Scholl M, Almkvist O, Wall A, Engler H, Langstrom B, et al. Evidence for astrocytosis in prodromal Alzheimer disease provided by 11Cdeuterium-L-deprenyl: a multitracer PET paradigm combining 11CPittsburgh compound B and 18 F-FDG. J Nucl Med. 2012;53:37-46.
    • (2012) J Nucl Med. , vol.53 , pp. 37-46
    • Carter, S.F.1    Scholl, M.2    Almkvist, O.3    Wall, A.4    Engler, H.5    Langstrom, B.6
  • 53
    • 78650698306 scopus 로고    scopus 로고
    • Positron emission tomography imaging and clinical progression in relation to molecular pathology in the first pittsburgh compound B positron emission tomography patient with Alzheimer's disease
    • Kadir A, Marutle A, Gonzalez D, Scholl M, Almkvist O, Mousavi M, et al. Positron emission tomography imaging and clinical progression in relation to molecular pathology in the first Pittsburgh Compound B positron emission tomography patient with Alzheimer's disease. Brain. 2010;134:301-17.
    • (2010) Brain. , vol.134 , pp. 301-317
    • Kadir, A.1    Marutle, A.2    Gonzalez, D.3    Scholl, M.4    Almkvist, O.5    Mousavi, M.6
  • 54
    • 84930981712 scopus 로고    scopus 로고
    • Comparing amyloid-β deposition, neuroinflammation, glucose metabolism, and mitochondrial complex I activity in brain: A PET study in aged monkeys
    • Tsukada H, Nishiyama S, Ohba H, Kanazawa M, Kakiuchi T, Harada N. Comparing amyloid-β deposition, neuroinflammation, glucose metabolism, and mitochondrial complex I activity in brain: a PET study in aged monkeys. Eur J Nucl Med Mol Imaging. 2014;41:2127-36.
    • (2014) Eur J Nucl Med Mol Imaging , vol.41 , pp. 2127-2136
    • Tsukada, H.1    Nishiyama, S.2    Ohba, H.3    Kanazawa, M.4    Kakiuchi, T.5    Harada, N.6
  • 56
    • 84928106559 scopus 로고    scopus 로고
    • Prefrontal hypometabolism in Alzheimer disease is related to longitudinal amyloid accumulation in remote brain regions
    • Klupp E, Grimmer T, Tahmasian M, Sorg C, Yakushev I, Yousefi BH, et al. Prefrontal hypometabolism in Alzheimer disease is related to longitudinal amyloid accumulation in remote brain regions. J Nucl Med. 2015;56:399-404.
    • (2015) J Nucl Med. , vol.56 , pp. 399-404
    • Klupp, E.1    Grimmer, T.2    Tahmasian, M.3    Sorg, C.4    Yakushev, I.5    Yousefi, B.H.6
  • 57
    • 34248190279 scopus 로고    scopus 로고
    • A beta oligomers - A decade of discovery
    • Walsh DM, Selkoe DJ. A beta oligomers - a decade of discovery. J Neurochem. 2007;101:1172-84.
    • (2007) J Neurochem. , vol.101 , pp. 1172-1184
    • Walsh, D.M.1    Selkoe, D.J.2
  • 58
    • 84892947356 scopus 로고    scopus 로고
    • Resting state fMRI reveals diminished functional connectivity in a mouse model of amyloidosis
    • Shah D, Jonckers E, Praet J, Vanhoutte G, Delgado y Palacios R, Bigot C, et al. Resting state fMRI reveals diminished functional connectivity in a mouse model of amyloidosis. PLoS One. 2013;8:e84241.
    • (2013) PLoS One , vol.8 , pp. e84241
    • Shah, D.1    Jonckers, E.2    Praet, J.3    Vanhoutte, G.4    Delgado-Y-Palacios, R.5    Bigot, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.