Early onset amyloid lesions lead to severe neuritic abnormalities and local, but not global neuron loss in APPPS1 transgenic mice

Neurobiology of Aging

Volumn 32, Issue 12, 2011, Pages 2324.e1-2324.e6

  Rupp, Niels J ^a,b   Wegenast Braun, Bettina M ^a,b   Radde, Rebecca ^a   Calhoun, Michael E ^a,c   Jucker, Mathias ^a,b  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^c Sinq Systems   (United States)

Author keywords

Alzheimer's disease; Hippocampus; Neocortex; Stereology

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; PRESENILIN 1;

AMYLOIDOSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CELL COUNT; CELL DENSITY; CELL LOSS; CEREBRAL BETA AMYLOIDOSIS; CONTROLLED STUDY; CYTOARCHITECTURE; DENTATE GYRUS; DISEASE MODEL; DISEASE SEVERITY; GRANULE CELL; MOUSE; NERVE CELL; NEURITIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEREOLOGY; TRANSGENIC MOUSE; WILD TYPE;

EID: 80053646630     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2010.08.014     Document Type: Article

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