Sesamin inhibits lipopolysaccharide-induced inflammation and extracellular matrix catabolism in rat intervertebral disc

Connective Tissue Research

Volumn 57, Issue 5, 2016, Pages 347-359

  Li, Kang ^a   Li, Yan ^a   Xu, Bo ^a   Mao, Lu ^a   Zhao, Jie ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

extracellular matrix; inflammation; intervertebral disc; lipopolysaccharide; organ culture; sesamin

Indexed keywords

AGENTS AFFECTING METABOLISM; AGGRECANASE 1; AGGRECANASE 2; ANTIINFLAMMATORY AGENT; BETA ACTIN; CHEMOTACTIC FACTOR; COLLAGENASE 3; CYCLOOXYGENASE 2; ENZYME INHIBITOR; HERBACEOUS AGENT; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERSTITIAL COLLAGENASE; LIPOPOLYSACCHARIDE; MACROPHAGE DERIVED CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PROSTAGLANDIN E2; PROTECTIVE AGENT; PROTEOGLYCAN; SESAMIN; STRESS ACTIVATED PROTEIN KINASE; STROMELYSIN; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR; 1,3 DIOXOLANE DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIGNAN; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CATABOLISM; CHONDROPROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISKITIS; DRUG EFFECT; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; EX VIVO STUDY; EXTRACELLULAR MATRIX; IN VITRO STUDY; INTERVERTEBRAL DISK DEGENERATION; MACROPHAGE MIGRATION INHIBITION; METABOLIC INHIBITION; NONHUMAN; ORGAN CULTURE; PROTEIN EXPRESSION; RAT; SESAME; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CELL MOTION; CELL SURVIVAL; CHEMICALLY INDUCED; DRUG EFFECTS; ENZYME ACTIVATION; GENETICS; INFLAMMATION; INTERVERTEBRAL DISK; MACROPHAGE; MAPK SIGNALING; METABOLISM; NUCLEUS PULPOSUS; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT;

ANIMALS; CELL MOVEMENT; CELL SURVIVAL; CELLS, CULTURED; CYCLOOXYGENASE 2; DINOPROSTONE; DIOXOLES; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; INFLAMMATION; INTERLEUKIN-1BETA; INTERVERTEBRAL DISC; INTERVERTEBRAL DISC DEGENERATION; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIGNANS; LIPOPOLYSACCHARIDES; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; NUCLEUS PULPOSUS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84973130345     PISSN: 03008207     EISSN: 16078438     Source Type: Journal    
DOI: 10.1080/03008207.2016.1182998     Document Type: Article

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