Lactoferricin mediates anti-inflammatory and anti-catabolic effects via inhibition of IL-1 and LPS activity in the intervertebral disc

Journal of Cellular Physiology

Volumn 228, Issue 9, 2013, Pages 1884-1896

  Kim, Jae Sung ^a   Ellman, Michael B ^a   Yan, Dongyao ^a   An, Howard S ^a   Kc, Ranjan ^a   Li, Xin ^a   Chen, Di ^a   Xiao, Guozhi ^a   Cs Szabo, Gabriella ^a   Hoskin, David W ^c   Buechter, Doug D ^d   Van Wijnen, Andre J ^e   Im, Hee Jeong ^a,b  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

^b University of Illinois at Chicago   (United States)

^c DALHOUSIE UNIVERSITY   (Canada)

^d Johnson Johnson Company   (United States)

^e MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGGRECANASE 1; AGGRECANASE 2; COLLAGENASE 3; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1; INTERLEUKIN 6; INTERSTITIAL COLLAGENASE; LACTOFERRICIN; LIPOPOLYSACCHARIDE; STROMELYSIN; SULFUR 35; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CATABOLISM; CATABOLITE REPRESSION; CELL COUNT; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DNA DETERMINATION; ENZYME ACTIVITY; ENZYME SYNTHESIS; EX VIVO STUDY; FEMALE; GENE EXPRESSION; HISTOLOGY; IN VITRO STUDY; INTERVERTEBRAL DISK; MALE; MICROINJECTION; MONOLAYER CULTURE; NONHUMAN; NUCLEUS PULPOSUS; ORGAN CULTURE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ZYMOGRAPHY;

ANIMALS; CATTLE; CELL SURVIVAL; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-1; INTERVERTEBRAL DISC; LACTOFERRIN; LIPOPOLYSACCHARIDES; LOW BACK PAIN; MICE; ORGAN CULTURE TECHNIQUES; PROTEOGLYCANS; RABBITS;

EID: 84878249684     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.24350     Document Type: Article

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