-
1
-
-
0001254287
-
Beitrage zur Kenntniss der Antipyretica
-
JV Mehring (1893) Beitrage zur Kenntniss der Antipyretica. Ther Monatsschr 7 577.
-
(1893)
Ther Monatsschr
, vol.7
, pp. 577
-
-
Mehring, J.V.1
-
2
-
-
84964114383
-
The history and usage of paracetamol
-
JB Spooner and JG Harvey (1976) The history and usage of paracetamol. J Int Med Res 4(4 Suppl), 1-6.
-
(1976)
J Int Med Res
, vol.4
, Issue.4
, pp. 1-6
-
-
Spooner, J.B.1
Harvey, J.G.2
-
3
-
-
0037126649
-
Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States
-
G Ostapowicz, RJ Fontana, FV Schiodt, et al. (2002) Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States. Ann Intern Med 137(12), 947-954.
-
(2002)
Ann Intern Med
, vol.137
, Issue.12
, pp. 947-954
-
-
Ostapowicz, G.1
Fontana, R.J.2
Schiodt, F.V.3
-
4
-
-
0037126533
-
-
[Summary for patients: PMID: 12484742.]
-
Ann Intern Med 137(12), I24. [Summary for patients: PMID: 12484742.]
-
(2002)
Ann Intern Med
, vol.137
, Issue.12
, pp. I24
-
-
-
5
-
-
0036734957
-
2001 annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System
-
TL Litovitz, W Klein-Schwartz, GC Rodgers Jr, et al. (2002) 2001 annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System. Am J Emerg Med 20(5), 391-452.
-
(2002)
Am J Emerg Med
, vol.20
, Issue.5
, pp. 391-452
-
-
Litovitz, T.L.1
Klein-Schwartz, W.2
Rodgers, G.C.3
-
6
-
-
32644474169
-
Acetaminophen-induced acute liver failure: Results of a United States multicenter prospective study
-
AM Larson, J Polson, RJ Fontana, et al. (2005) Acetaminophen-induced acute liver failure: Results of a United States multicenter prospective study. Hepatology 42(6), 1364-1372.
-
(2005)
Hepatology
, vol.42
, Issue.6
, pp. 1364-1372
-
-
Larson, A.M.1
Polson, J.2
Fontana, R.J.3
-
7
-
-
0037108979
-
COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression [see comment]
-
NV Chandrasekharan, H Dai, KL Roos, et al. (2002) COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression [see comment]. Proc Natl Acad Sci U S A 99(21), 13926-13931.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.21
, pp. 13926-13931
-
-
Chandrasekharan, N.V.1
Dai, H.2
Roos, K.L.3
-
8
-
-
0034457719
-
Mechanism of action of acetaminophen: is there a cyclooxygenase 3?
-
RM Botting (2000) Mechanism of action of acetaminophen: is there a cyclooxygenase 3? Clin Infect Dis 31(Suppl 5), 202-210.
-
(2000)
Clin Infect Dis
, vol.31
, pp. 202-210
-
-
Botting, R.M.1
-
9
-
-
0037460805
-
COX-3: just another COX or the solitary elusive target of paracetamol?
-
JM Schwab, HJ Schluesener and S Laufer (2003) COX-3: just another COX or the solitary elusive target of paracetamol? Lancet 361(9362), 981-982.
-
(2003)
Lancet
, vol.361
, Issue.9362
, pp. 981-982
-
-
Schwab, J.M.1
Schluesener, H.J.2
Laufer, S.3
-
11
-
-
0019139489
-
Kinetics and metabolism of paracetamol and phenacetin
-
LF Prescott (1980) Kinetics and metabolism of paracetamol and phenacetin. Br J Clin Pharmacol 10(Suppl 2), 291-298.
-
(1980)
Br J Clin Pharmacol
, vol.10
, pp. 291-298
-
-
Prescott, L.F.1
-
12
-
-
0022917632
-
Paracetamol and phenacetin
-
SP Clissold (1986) Paracetamol and phenacetin. Drugs 32(Suppl 4), 46-59.
-
(1986)
Drugs
, vol.32
, pp. 46-59
-
-
Clissold, S.P.1
-
13
-
-
0021194549
-
Renal clearance and serum protein binding of acetaminophen and its major conjugates in humans
-
ME Morris and G Levy (1984) Renal clearance and serum protein binding of acetaminophen and its major conjugates in humans. J Pharm Sci 73(8), 1038-1041.
-
(1984)
J Pharm Sci
, vol.73
, Issue.8
, pp. 1038-1041
-
-
Morris, M.E.1
Levy, G.2
-
14
-
-
0016516081
-
Evidence of placental transfer of acetaminophen [Letter]
-
G Levy, LK Garrettson and DM Soda (1975) Evidence of placental transfer of acetaminophen [Letter]. Pediatrics 55(6), 895.
-
(1975)
Pediatrics
, vol.55
, Issue.6
, pp. 895
-
-
Levy, G.1
Garrettson, L.K.2
Soda, D.M.3
-
15
-
-
0028308938
-
Paracetamol pharmacokinetics during the first trimester of human pregnancy
-
L Beaulac-Baillargeon and S Rocheleau (1994) Paracetamol pharmacokinetics during the first trimester of human pregnancy. Eur J Clin Pharmacol 46(5), 451-454.
-
(1994)
Eur J Clin Pharmacol
, vol.46
, Issue.5
, pp. 451-454
-
-
Beaulac-Baillargeon, L.1
Rocheleau, S.2
-
16
-
-
0022966650
-
Acetaminophen pharmacokinetics: comparison between pregnant and nonpregnant women
-
W Rayburn, U Shukla, P Stetson, et al. (1986) Acetaminophen pharmacokinetics: comparison between pregnant and nonpregnant women. Am J Obstet Gynecol 155(6), 1353-1356.
-
(1986)
Am J Obstet Gynecol
, vol.155
, Issue.6
, pp. 1353-1356
-
-
Rayburn, W.1
Shukla, U.2
Stetson, P.3
-
17
-
-
0020053160
-
Acetaminophen overdose in the third trimester of pregnancy
-
AJ Byer, TR Traylor and JR Semmer (1982) Acetaminophen overdose in the third trimester of pregnancy. JAMA 247(22), 3114-3115.
-
(1982)
JAMA
, vol.247
, Issue.22
, pp. 3114-3115
-
-
Byer, A.J.1
Traylor, T.R.2
Semmer, J.R.3
-
18
-
-
0027200467
-
Cesarean section after maternal acetaminophen overdose
-
S Friedman, M Gatti and T Baker (1993) Cesarean section after maternal acetaminophen overdose. Anesth Analg 77(3), 632-634.
-
(1993)
Anesth Analg
, vol.77
, Issue.3
, pp. 632-634
-
-
Friedman, S.1
Gatti, M.2
Baker, T.3
-
19
-
-
0022607003
-
Maternal acetaminophen overdose at 15 weeks of gestation
-
J Ludmir, DM Main, MB Landon, et al. (1986) Maternal acetaminophen overdose at 15 weeks of gestation. Obstet Gynecol 67(5), 750-751.
-
(1986)
Obstet Gynecol
, vol.67
, Issue.5
, pp. 750-751
-
-
Ludmir, J.1
Main, D.M.2
Landon, M.B.3
-
20
-
-
0030952368
-
Paracetamol overdose in pregnancy: analysis of the outcomes of 300 cases referred to the Teratology Information Service
-
PR McElhatton, FM Sullivan and GN Volans (1997) Paracetamol overdose in pregnancy: analysis of the outcomes of 300 cases referred to the Teratology Information Service. Reprod Toxicol 11(1), 85-94.
-
(1997)
Reprod Toxicol
, vol.11
, Issue.1
, pp. 85-94
-
-
McElhatton, P.R.1
Sullivan, F.M.2
Volans, G.N.3
-
21
-
-
0024398922
-
Acute acetaminophen overdose during pregnancy
-
BS Riggs, AC Bronstien, K Kulig, et al. (1989) Acute acetaminophen overdose during pregnancy. Obstet Gynecol 74(2), 247-253.
-
(1989)
Obstet Gynecol
, vol.74
, Issue.2
, pp. 247-253
-
-
Riggs, B.S.1
Bronstien, A.C.2
Kulig, K.3
-
22
-
-
0024574167
-
Favourable neonatal outcome following maternal paracetamol overdose and severe fetal distress. Case report
-
SK Rosevear and PL Hope (1989) Favourable neonatal outcome following maternal paracetamol overdose and severe fetal distress. Case report. Br J Obstet Gynaecol 96(4), 491-493.
-
(1989)
Br J Obstet Gynaecol
, vol.96
, Issue.4
, pp. 491-493
-
-
Rosevear, S.K.1
Hope, P.L.2
-
23
-
-
0021329136
-
Paracetamol overdose in the second trimester of pregnancy. Case report
-
IM Stokes (1984) Paracetamol overdose in the second trimester of pregnancy. Case report. Br J Obstet Gynaecol 91(3), 286-288.
-
(1984)
Br J Obstet Gynaecol
, vol.91
, Issue.3
, pp. 286-288
-
-
Stokes, I.M.1
-
24
-
-
0030788456
-
Acetaminophen poisoning in late pregnancy. A case report
-
PH Wang, MJ Yang, WL Lee, et al. (1997) Acetaminophen poisoning in late pregnancy. A case report. J Reprod Med 42(6), 367-371.
-
(1997)
J Reprod Med
, vol.42
, Issue.6
, pp. 367-371
-
-
Wang, P.H.1
Yang, M.J.2
Lee, W.L.3
-
25
-
-
0019520552
-
Analgesic drugs in breast milk and plasma
-
JW Findlay, RL DeAngelis, MF Kearney, et al. (1981) Analgesic drugs in breast milk and plasma. Clin Pharmacol Ther 29(5), 625-633.
-
(1981)
Clin Pharmacol Ther
, vol.29
, Issue.5
, pp. 625-633
-
-
Findlay, J.W.1
DeAngelis, R.L.2
Kearney, M.F.3
-
26
-
-
0027938549
-
Delayed toxic acetaminophen level after initial four hour nontoxic level
-
TV Tighe and FG Walter (1994) Delayed toxic acetaminophen level after initial four hour nontoxic level. J Toxicol Clin Toxicol 32(4), 431-434.
-
(1994)
J Toxicol Clin Toxicol
, vol.32
, Issue.4
, pp. 431-434
-
-
Tighe, T.V.1
Walter, F.G.2
-
28
-
-
84958895726
-
Delayed rise in serum drug levels in overdose patients despite multiple dose charcoal and after charcoal stools
-
WL Augenstien, KW Kulig and BH Rumack (1987) Delayed rise in serum drug levels in overdose patients despite multiple dose charcoal and after charcoal stools. Vet Hum Toxicol 29 491.
-
(1987)
Vet Hum Toxicol
, vol.29
, pp. 491
-
-
Augenstien, W.L.1
Kulig, K.W.2
Rumack, B.H.3
-
29
-
-
0014029833
-
Liver damage and impaired glucose tolerance after paracetamol overdosage
-
JS Thomson and LF Prescott (1966) Liver damage and impaired glucose tolerance after paracetamol overdosage. BMJ 5512 506-507.
-
(1966)
BMJ
, vol.5512
, pp. 506-507
-
-
Thomson, J.S.1
Prescott, L.F.2
-
30
-
-
0014029813
-
Acute liver necrosis following overdose of paracetamol
-
DG Davidson and WN Eastham (1966) Acute liver necrosis following overdose of paracetamol. BMJ 5512 497-499.
-
(1966)
BMJ
, vol.5512
, pp. 497-499
-
-
Davidson, D.G.1
Eastham, W.N.2
-
31
-
-
0015748302
-
Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism
-
JR Mitchell, DJ Jollow, WZ Potter, et al. (1973) Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism. J Pharmacol Exp Ther 187(1), 185-194.
-
(1973)
J Pharmacol Exp Ther
, vol.187
, Issue.1
, pp. 185-194
-
-
Mitchell, J.R.1
Jollow, D.J.2
Potter, W.Z.3
-
32
-
-
0015733053
-
Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione
-
JR Mitchell, et al. (1973) Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione. J Pharmacol Exp Ther 187(1), 211-217.
-
(1973)
J Pharmacol Exp Ther
, vol.187
, Issue.1
, pp. 211-217
-
-
Mitchell, J.R.1
-
33
-
-
0016209023
-
Acetaminophen-induced hepatic injury: protective role of glutathione in man and rationale for therapy
-
JR Mitchell, SS Thorgiersson, WZ Potter, et al. (1974) Acetaminophen-induced hepatic injury: protective role of glutathione in man and rationale for therapy. Clin Pharmacol Ther 16(4), 676-684.
-
(1974)
Clin Pharmacol Ther
, vol.16
, Issue.4
, pp. 676-684
-
-
Mitchell, J.R.1
Thorgiersson, S.S.2
Potter, W.Z.3
-
34
-
-
0015754446
-
Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo
-
DJ Jollow, JR Mitchell, WZ Potter, et al. (1973) Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo. J Pharmacol Exp Ther 187(1), 195-202.
-
(1973)
J Pharmacol Exp Ther
, vol.187
, Issue.1
, pp. 195-202
-
-
Jollow, D.J.1
Mitchell, J.R.2
Potter, W.Z.3
-
35
-
-
0021345926
-
N-acetyl-p-benzoquinone imine: a cytochrome P-450-mediated oxidation product of acetaminophen
-
DC Dahlin, FT Miwa, AY Lu, et al. (1984) N-acetyl-p-benzoquinone imine: a cytochrome P-450-mediated oxidation product of acetaminophen. Proc Natl Acad Sci U S A 81(5), 1327-1331.
-
(1984)
Proc Natl Acad Sci U S A
, vol.81
, Issue.5
, pp. 1327-1331
-
-
Dahlin, D.C.1
Miwa, F.T.2
Lu, A.Y.3
-
36
-
-
0025694879
-
Molecular mechanisms of the hepatotoxicity caused by acetaminophen
-
SD Nelson (1990) Molecular mechanisms of the hepatotoxicity caused by acetaminophen. Semin Liver Dis 10(4), 267-278.
-
(1990)
Semin Liver Dis
, vol.10
, Issue.4
, pp. 267-278
-
-
Nelson, S.D.1
-
37
-
-
0032504193
-
Identification of the hepatic protein targets of reactive metabolites of acetaminophen in vivo in mice using two-dimensional gel electrophoresis and mass spectrometry
-
Y Qiu, LZ Benet and AL Burlingame (1998) Identification of the hepatic protein targets of reactive metabolites of acetaminophen in vivo in mice using two-dimensional gel electrophoresis and mass spectrometry. J Biol Chem 273(28), 17940-17953.
-
(1998)
J Biol Chem
, vol.273
, Issue.28
, pp. 17940-17953
-
-
Qiu, Y.1
Benet, L.Z.2
Burlingame, A.L.3
-
38
-
-
0043135016
-
The role of oxidant stress and reactive nitrogen species in acetaminophen hepatotoxicity
-
H Jaeschke, TR Knight and ML Bajt (2003) The role of oxidant stress and reactive nitrogen species in acetaminophen hepatotoxicity. Toxicol Lett 144(3), 279-288.
-
(2003)
Toxicol Lett
, vol.144
, Issue.3
, pp. 279-288
-
-
Jaeschke, H.1
Knight, T.R.2
Bajt, M.L.3
-
39
-
-
0030744291
-
Selective protein arylation and acetaminophen-induced hepatotoxicity
-
SD Cohen and EA Khairallah (1997) Selective protein arylation and acetaminophen-induced hepatotoxicity. Drug Metab Rev 29(1–2), 59-77.
-
(1997)
Drug Metab Rev
, vol.29
, Issue.1-2
, pp. 59-77
-
-
Cohen, S.D.1
Khairallah, E.A.2
-
40
-
-
0031409480
-
-
[erratum]
-
Drug Metab Rev 29(4), 1285. [erratum]
-
(1997)
Drug Metab Rev
, vol.29
, Issue.4
, pp. 1285
-
-
-
41
-
-
0007739903
-
Covalent binding and acute lethal injury in vivo: how has the original hypothesis survived a decade of critical examination?
-
GR Wilkinson, MD Rawlins (Eds), Lancaster, UK: MTP Press
-
CV Smith, BH Lauterberg and JR Mitchell (1985) Covalent binding and acute lethal injury in vivo: how has the original hypothesis survived a decade of critical examination? GR Wilkinson, MD Rawlins (Eds) Drug Metabolism and Disposition: Considerations in Clinical Pharmacology Lancaster, UK: MTP Press 161-181.
-
(1985)
Drug Metabolism and Disposition: Considerations in Clinical Pharmacology
, pp. 161-181
-
-
Smith, C.V.1
Lauterberg, B.H.2
Mitchell, J.R.3
-
42
-
-
0033000310
-
Pretreatment of mice with macrophage inactivators decreases acetaminophen hepatotoxicity and the formation of reactive oxygen and nitrogen species
-
SL Michael, NR Rumford, PR Mayeux, et al. (1999) Pretreatment of mice with macrophage inactivators decreases acetaminophen hepatotoxicity and the formation of reactive oxygen and nitrogen species. Hepatology 30(1), 186-195.
-
(1999)
Hepatology
, vol.30
, Issue.1
, pp. 186-195
-
-
Michael, S.L.1
Rumford, N.R.2
Mayeux, P.R.3
-
43
-
-
0028948724
-
Modulation of macrophage functioning abrogates the acute hepatotoxicity of acetaminophen
-
DL Laskin, CR Gardiner, VF Price, et al. (1995) Modulation of macrophage functioning abrogates the acute hepatotoxicity of acetaminophen. Hepatology 21(4), 1045-1050.
-
(1995)
Hepatology
, vol.21
, Issue.4
, pp. 1045-1050
-
-
Laskin, D.L.1
Gardiner, C.R.2
Price, V.F.3
-
44
-
-
85033071756
-
Sex- and age-dependent acetaminophen hepato- and nephrotoxicity in Sprague-Dawley rats: role of tissue accumulation, nonprotein sulfhydryl depletion, and covalent binding
-
JB Tarloff, EA Khaifallah, SD Cohen, et al. (1996) Sex- and age-dependent acetaminophen hepato- and nephrotoxicity in Sprague-Dawley rats: role of tissue accumulation, nonprotein sulfhydryl depletion, and covalent binding. Fund Appl Toxicol 30(1), 13-22.
-
(1996)
Fund Appl Toxicol
, vol.30
, Issue.1
, pp. 13-22
-
-
Tarloff, J.B.1
Khaifallah, E.A.2
Cohen, S.D.3
-
45
-
-
0024345539
-
Subcellular binding and effects on calcium homeostasis produced by acetaminophen and a nonhepatotoxic regioisomer, 3′-hydroxyacetanilide, in mouse liver
-
MA Tirmenstein and SD Nelson (1989) Subcellular binding and effects on calcium homeostasis produced by acetaminophen and a nonhepatotoxic regioisomer, 3′-hydroxyacetanilide, in mouse liver. J Biol Chem 264(17), 9814-9819.
-
(1989)
J Biol Chem
, vol.264
, Issue.17
, pp. 9814-9819
-
-
Tirmenstein, M.A.1
Nelson, S.D.2
-
46
-
-
0028950762
-
A comparative study of mouse liver proteins arylated by reactive metabolites of acetaminophen and its nonhepatotoxic regioisomer, 3′-hydroxyacetanilide
-
TG Myers, EC Dietz, NL Anderson, et al. (1995) A comparative study of mouse liver proteins arylated by reactive metabolites of acetaminophen and its nonhepatotoxic regioisomer, 3′-hydroxyacetanilide. Chem Res Toxicol 8(3), 403-413.
-
(1995)
Chem Res Toxicol
, vol.8
, Issue.3
, pp. 403-413
-
-
Myers, T.G.1
Dietz, E.C.2
Anderson, N.L.3
-
47
-
-
0019518322
-
Drug-induced lipid peroxidation in mice. I. Modulation by monooxygenase activity, glutathione and selenium status
-
A Wendel and S Feuerstein (1981) Drug-induced lipid peroxidation in mice. I. Modulation by monooxygenase activity, glutathione and selenium status. Biochem Pharmacol 30(18), 2513-2520.
-
(1981)
Biochem Pharmacol
, vol.30
, Issue.18
, pp. 2513-2520
-
-
Wendel, A.1
Feuerstein, S.2
-
48
-
-
0020438499
-
Drug-induced lipid peroxidation in mice. II. Protection against paracetamol-induced liver necrosis by intravenous liposomally entrapped glutathione
-
A Wendel, H Jaeschke and M Gloger (1982) Drug-induced lipid peroxidation in mice. II. Protection against paracetamol-induced liver necrosis by intravenous liposomally entrapped glutathione. Biochem Pharmacol 31(22), 3601-3605.
-
(1982)
Biochem Pharmacol
, vol.31
, Issue.22
, pp. 3601-3605
-
-
Wendel, A.1
Jaeschke, H.2
Gloger, M.3
-
49
-
-
0018763569
-
Acute paracetamol intoxication of starved mice leads to lipid peroxidation in vivo
-
A Wendel, S Feuerstein and KH Konz (1979) Acute paracetamol intoxication of starved mice leads to lipid peroxidation in vivo. Biochem Pharmacol 28(13), 2051-2055.
-
(1979)
Biochem Pharmacol
, vol.28
, Issue.13
, pp. 2051-2055
-
-
Wendel, A.1
Feuerstein, S.2
Konz, K.H.3
-
50
-
-
0019566695
-
Overview of alkylation and peroxidation mechanisms in acute lethal hepatocellular injury by chemically reactive metabolites
-
JR Mitchell, CV Smith, H Hughes, et al. (1981) Overview of alkylation and peroxidation mechanisms in acute lethal hepatocellular injury by chemically reactive metabolites. Semin Liver Dis 1(2), 143-150.
-
(1981)
Semin Liver Dis
, vol.1
, Issue.2
, pp. 143-150
-
-
Mitchell, J.R.1
Smith, C.V.2
Hughes, H.3
-
51
-
-
0032171410
-
Oxidative chemistry of nitric oxide: the roles of superoxide, peroxynitrite, and carbon dioxide
-
GL Squadrito and WA Pryor (1998) Oxidative chemistry of nitric oxide: the roles of superoxide, peroxynitrite, and carbon dioxide. Free Radic Biol Med 25(4–5), 392-403.
-
(1998)
Free Radic Biol Med
, vol.25
, Issue.4-5
, pp. 392-403
-
-
Squadrito, G.L.1
Pryor, W.A.2
-
52
-
-
0025156808
-
Mitochondrial dysfunction in paracetamol hepatotoxicity: in vitro studies in isolated mouse hepatocytes
-
PC Burcham and AW Harman (1990) Mitochondrial dysfunction in paracetamol hepatotoxicity: in vitro studies in isolated mouse hepatocytes. Toxicol Lett 50(1), 37-48.
-
(1990)
Toxicol Lett
, vol.50
, Issue.1
, pp. 37-48
-
-
Burcham, P.C.1
Harman, A.W.2
-
53
-
-
0036147966
-
Genomics and proteomics analysis of acetaminophen toxicity in mouse liver
-
SU Ruepp, RP Tonge, J Shaw, et al. (2002) Genomics and proteomics analysis of acetaminophen toxicity in mouse liver. Toxicol Sci 65(1), 135-150.
-
(2002)
Toxicol Sci
, vol.65
, Issue.1
, pp. 135-150
-
-
Ruepp, S.U.1
Tonge, R.P.2
Shaw, J.3
-
54
-
-
0021051424
-
Scanning electron microscopic examination of acetaminophen-induced hepatotoxicity and congestion in mice
-
RM Walker, WJ Racz and TF McElligott (1983) Scanning electron microscopic examination of acetaminophen-induced hepatotoxicity and congestion in mice. Am J Pathol 113(3), 321-330.
-
(1983)
Am J Pathol
, vol.113
, Issue.3
, pp. 321-330
-
-
Walker, R.M.1
Racz, W.J.2
McElligott, T.F.3
-
55
-
-
0027976561
-
Inhibition of mitochondrial respiration in vivo is an early event in acetaminophen-induced hepatotoxicity
-
PJ Donnelly, RM Walker and WJ Racz (1994) Inhibition of mitochondrial respiration in vivo is an early event in acetaminophen-induced hepatotoxicity. Arch Toxicol 68(2), 110-118.
-
(1994)
Arch Toxicol
, vol.68
, Issue.2
, pp. 110-118
-
-
Donnelly, P.J.1
Walker, R.M.2
Racz, W.J.3
-
56
-
-
0024531786
-
Impaired mitochondrial oxidative energy metabolism following paracetamol-induced hepatotoxicity in the rat
-
SS Katyare and JG Satav (1989) Impaired mitochondrial oxidative energy metabolism following paracetamol-induced hepatotoxicity in the rat. Br J Pharmacol 96(1), 51-58.
-
(1989)
Br J Pharmacol
, vol.96
, Issue.1
, pp. 51-58
-
-
Katyare, S.S.1
Satav, J.G.2
-
57
-
-
0023904377
-
Acetaminophen-induced inhibition of hepatic mitochondrial respiration in mice
-
LL Meyers, WP Beierschmidt, EA Khairallah, et al. (1988) Acetaminophen-induced inhibition of hepatic mitochondrial respiration in mice. Toxicol Appl Pharmacol 93(3), 378-387.
-
(1988)
Toxicol Appl Pharmacol
, vol.93
, Issue.3
, pp. 378-387
-
-
Meyers, L.L.1
Beierschmidt, W.P.2
Khairallah, E.A.3
-
58
-
-
0022889258
-
Effect of hyperoxia on liver necrosis induced by hepatotoxins
-
L Marzella, K Muhvich and RA Myers (1986) Effect of hyperoxia on liver necrosis induced by hepatotoxins. Virchows Arch 51(6), 497-507.
-
(1986)
Virchows Arch
, vol.51
, Issue.6
, pp. 497-507
-
-
Marzella, L.1
Muhvich, K.2
Myers, R.A.3
-
59
-
-
33745479766
-
Hyperbaric oxygen reduces acetaminophen toxicity and increases HIF-1alpha expression
-
SD Salhanick, B Belikoff, D Orlow, et al. (2006) Hyperbaric oxygen reduces acetaminophen toxicity and increases HIF-1alpha expression. Acad Emerg Med 13(7), 707-714.
-
(2006)
Acad Emerg Med
, vol.13
, Issue.7
, pp. 707-714
-
-
Salhanick, S.D.1
Belikoff, B.2
Orlow, D.3
-
60
-
-
0025813152
-
Hyperbaric oxygen treatment for carbon tetrachloride poisoning
-
KK Burkhart, AH Hall, R Gerace and BH Rumack (1991) Hyperbaric oxygen treatment for carbon tetrachloride poisoning. Drug Saf 6(5), 332-338.
-
(1991)
Drug Saf
, vol.6
, Issue.5
, pp. 332-338
-
-
Burkhart, K.K.1
Hall, A.H.2
Gerace, R.3
Rumack, B.H.4
-
61
-
-
0030990409
-
Chronic enteral ethanol treatment causes hypoxia in rat liver tissue in vivo
-
GE Arteel, Y Iimuro, M Yin, et al. (1997) Chronic enteral ethanol treatment causes hypoxia in rat liver tissue in vivo. Hepatology 25(4), 920-926.
-
(1997)
Hepatology
, vol.25
, Issue.4
, pp. 920-926
-
-
Arteel, G.E.1
Iimuro, Y.2
Yin, M.3
-
62
-
-
0029781891
-
Acute alcohol produces hypoxia directly in rat liver tissue in vivo: role of Kupffer cells
-
GE Arteel, JA Raleigh, BU Bradford, et al. (1996) Acute alcohol produces hypoxia directly in rat liver tissue in vivo: role of Kupffer cells. Am J Physiol 271(3 Pt 1), G494-G500.
-
(1996)
Am J Physiol
, vol.271
, Issue.3
, pp. G494-G500
-
-
Arteel, G.E.1
Raleigh, J.A.2
Bradford, B.U.3
-
63
-
-
0030744291
-
Selective protein arylation and acetaminophen-induced hepatotoxicity
-
SD Cohen and EA Khairallah (1997) Selective protein arylation and acetaminophen-induced hepatotoxicity. Drug Metab Rev 29(1–2), 59-77.
-
(1997)
Drug Metab Rev
, vol.29
, Issue.1-2
, pp. 59-77
-
-
Cohen, S.D.1
Khairallah, E.A.2
-
64
-
-
0031409480
-
-
[erratum].
-
Drug Metab Rev 29(4), 1285. [erratum].
-
(1997)
Drug Metab Rev
, vol.29
, Issue.4
, pp. 1285
-
-
-
65
-
-
0028350768
-
Alcohol and the liver: 1994 update
-
CS Lieber (1994) Alcohol and the liver: 1994 update. Gastroenterology 106 1085-1105.
-
(1994)
Gastroenterology
, vol.106
, pp. 1085-1105
-
-
Lieber, C.S.1
-
67
-
-
0035132183
-
Paracetamol (acetaminophen)-induced toxicity: molecular and biochemical mechanisms, analogues and protective approaches
-
JG Bessems and NP Vermeulen (2001) Paracetamol (acetaminophen)-induced toxicity: molecular and biochemical mechanisms, analogues and protective approaches. Crit Rev Toxicol 31(1), 55-138.
-
(2001)
Crit Rev Toxicol
, vol.31
, Issue.1
, pp. 55-138
-
-
Bessems, J.G.1
Vermeulen, N.P.2
-
68
-
-
0029041017
-
The temporal profile of increased transaminase levels in patients with acetaminophen-induced liver dysfunction
-
AJ Singer, TR Carracio and HC Mofenson (1995) The temporal profile of increased transaminase levels in patients with acetaminophen-induced liver dysfunction. Ann Emerg Med 26(1), 49-53.
-
(1995)
Ann Emerg Med
, vol.26
, Issue.1
, pp. 49-53
-
-
Singer, A.J.1
Carracio, T.R.2
Mofenson, H.C.3
-
69
-
-
0034869402
-
Nephrotoxicity after acute severe acetaminophen poisoning in adolescents
-
K Boutis and M Shannon (2001) Nephrotoxicity after acute severe acetaminophen poisoning in adolescents. J Toxicol Clin Toxicol 39(5), 441-445.
-
(2001)
J Toxicol Clin Toxicol
, vol.39
, Issue.5
, pp. 441-445
-
-
Boutis, K.1
Shannon, M.2
-
70
-
-
0029094577
-
Acute renal failure due to acetaminophen ingestion: a case report and review of the literature
-
P Blakely and BR McDonald (1995) Acute renal failure due to acetaminophen ingestion: a case report and review of the literature. J Am Soc Nephrol 6(1), 48-53.
-
(1995)
J Am Soc Nephrol
, vol.6
, Issue.1
, pp. 48-53
-
-
Blakely, P.1
McDonald, B.R.2
-
71
-
-
0022588275
-
Centrilobular hepatic fibrosis following acetaminophen-induced hepatic necrosis in an alcoholic
-
JR O'Dell, RK Zetterman and DA Burnett (1986) Centrilobular hepatic fibrosis following acetaminophen-induced hepatic necrosis in an alcoholic. JAMA 255(19), 2636-2637.
-
(1986)
JAMA
, vol.255
, Issue.19
, pp. 2636-2637
-
-
O'Dell, J.R.1
Zetterman, R.K.2
Burnett, D.A.3
-
72
-
-
33745607004
-
Aminotranferase elevations in healthy adults receiving 4 grams of acetaminophen daily: a randomized controlled trial
-
PB Watkins, N Kaplowitz, JT Slattery, et al. (2006) Aminotranferase elevations in healthy adults receiving 4 grams of acetaminophen daily: a randomized controlled trial. JAMA 296(1), 87-93.
-
(2006)
JAMA
, vol.296
, Issue.1
, pp. 87-93
-
-
Watkins, P.B.1
Kaplowitz, N.2
Slattery, J.T.3
-
73
-
-
0030017744
-
Acetaminophen and adverse chronic renal outcomes: an appraisal of the epidemiologic evidence
-
BJ Barrett (1996) Acetaminophen and adverse chronic renal outcomes: an appraisal of the epidemiologic evidence. Am J Kidney Dis 28(1 Suppl 1), 14-19.
-
(1996)
Am J Kidney Dis
, vol.28
, Issue.1
, pp. 14-19
-
-
Barrett, B.J.1
-
74
-
-
0030037399
-
Acetaminophen: acute and chronic effects on renal function
-
RC Blantz (1996) Acetaminophen: acute and chronic effects on renal function. Am J Kidney Dis 28(1 Suppl 1), 3-6.
-
(1996)
Am J Kidney Dis
, vol.28
, Issue.1
, pp. 3-6
-
-
Blantz, R.C.1
-
75
-
-
0030017604
-
Habitual use of acetaminophen as a risk factor for chronic renal failure: a comparison with phenacetin
-
VM Buckalew Jr (1996) Habitual use of acetaminophen as a risk factor for chronic renal failure: a comparison with phenacetin. Am J Kidney Dis 28(1 Suppl 1), 7-13.
-
(1996)
Am J Kidney Dis
, vol.28
, Issue.1
, pp. 7-13
-
-
Buckalew, V.M.1
-
76
-
-
0036226892
-
Acetaminophen hepatotoxicity: the first 35 years
-
BH Rumack (2002) Acetaminophen hepatotoxicity: the first 35 years. J Toxicol Clin Toxicol 40(1), 3-20.
-
(2002)
J Toxicol Clin Toxicol
, vol.40
, Issue.1
, pp. 3-20
-
-
Rumack, B.H.1
-
77
-
-
0022570529
-
Coma and metabolic acidosis early in severe acute paracetamol poisoning
-
RJ Flanagan and TG Mant (1986) Coma and metabolic acidosis early in severe acute paracetamol poisoning. Hum Toxicol 5(3), 179-182.
-
(1986)
Hum Toxicol
, vol.5
, Issue.3
, pp. 179-182
-
-
Flanagan, R.J.1
Mant, T.G.2
-
78
-
-
0024341761
-
Reversible and irreversible inhibition of hepatic mitochondrial respiration by acetaminophen and its toxic metabolite, N-acetyl-p-benzoquinoneimine (NAPQI)
-
RL Esterline, SD Ray and S Ji (1989) Reversible and irreversible inhibition of hepatic mitochondrial respiration by acetaminophen and its toxic metabolite, N-acetyl-p-benzoquinoneimine (NAPQI). Biochem Pharmacol 38(14), 2387-2390.
-
(1989)
Biochem Pharmacol
, vol.38
, Issue.14
, pp. 2387-2390
-
-
Esterline, R.L.1
Ray, S.D.2
Ji, S.3
-
79
-
-
0028347377
-
Acute hepatic and renal toxicity from low doses of acetaminophen in the absence of alcohol abuse or malnutrition: evidence for increased susceptibility to drug toxicity due to cardiopulmonary and renal insufficiency
-
HL Bonkovsky, et al. (1994) Acute hepatic and renal toxicity from low doses of acetaminophen in the absence of alcohol abuse or malnutrition: evidence for increased susceptibility to drug toxicity due to cardiopulmonary and renal insufficiency. Hepatology 19(5), 1141-1148.
-
(1994)
Hepatology
, vol.19
, Issue.5
, pp. 1141-1148
-
-
Bonkovsky, H.L.1
-
80
-
-
0023549728
-
The effect of activated charcoal on N-acetylcysteine absorption in normal subjects
-
BR Ekins, DC Ford, MI Thompson, et al. (1987) The effect of activated charcoal on N-acetylcysteine absorption in normal subjects. Am J Emerg Med 5(6), 483-487.
-
(1987)
Am J Emerg Med
, vol.5
, Issue.6
, pp. 483-487
-
-
Ekins, B.R.1
Ford, D.C.2
Thompson, M.I.3
-
81
-
-
0028222859
-
A prospective evaluation of the effect of activated charcoal before oral N-acetylcysteine in acetaminophen overdose [see comment]
-
HA Spiller, EP Krenzelok, GA Grande, et al. (1994) A prospective evaluation of the effect of activated charcoal before oral N-acetylcysteine in acetaminophen overdose [see comment]. Ann Emerg Med 23(3), 519-523.
-
(1994)
Ann Emerg Med
, vol.23
, Issue.3
, pp. 519-523
-
-
Spiller, H.A.1
Krenzelok, E.P.2
Grande, G.A.3
-
82
-
-
0028088462
-
A new loading dose for N-acetylcysteine? The answer is no [see comment]
-
MJ Smilkstein (1994) A new loading dose for N-acetylcysteine? The answer is no [see comment]. Ann Emerg Med 24(3), 538-539.
-
(1994)
Ann Emerg Med
, vol.24
, Issue.3
, pp. 538-539
-
-
Smilkstein, M.J.1
-
83
-
-
0030639567
-
Acetaminophen-induced hepatotoxicity: predisposing factors and treatments
-
AJ Makin and R Williams (1997) Acetaminophen-induced hepatotoxicity: predisposing factors and treatments. Adv Intern Med 42 453-483.
-
(1997)
Adv Intern Med
, vol.42
, pp. 453-483
-
-
Makin, A.J.1
Williams, R.2
-
84
-
-
0037116856
-
Blood lactate as an early predictor of outcome in paracetamol-induced acute liver failure: a cohort study [see comment]
-
W Bernal, N Donaldson, D Wyncoll, et al. (2002) Blood lactate as an early predictor of outcome in paracetamol-induced acute liver failure: a cohort study [see comment]. Lancet 359(9306), 558-563.
-
(2002)
Lancet
, vol.359
, Issue.9306
, pp. 558-563
-
-
Bernal, W.1
Donaldson, N.2
Wyncoll, D.3
-
85
-
-
0033653694
-
Acetaminophen causes an increased International Normalized Ratio by reducing functional factor VII
-
IM Whyte, NA Buckley, DM Reith, et al. (2000) Acetaminophen causes an increased International Normalized Ratio by reducing functional factor VII. Ther Drug Monit 22(6), 742-748.
-
(2000)
Ther Drug Monit
, vol.22
, Issue.6
, pp. 742-748
-
-
Whyte, I.M.1
Buckley, N.A.2
Reith, D.M.3
-
86
-
-
0037068944
-
Effect of acetylcysteine on prothrombin index in paracetamol poisoning without hepatocellular injury [see comment]
-
LE Schmidt, TT Knudsen, K Dalhoff, et al. (2002) Effect of acetylcysteine on prothrombin index in paracetamol poisoning without hepatocellular injury [see comment]. Lancet 360(9340), 1151-1152.
-
(2002)
Lancet
, vol.360
, Issue.9340
, pp. 1151-1152
-
-
Schmidt, L.E.1
Knudsen, T.T.2
Dalhoff, K.3
-
87
-
-
0038581620
-
A 20-hour treatment for acute acetaminophen overdose
-
L Yip and RC Dart (2003) A 20-hour treatment for acute acetaminophen overdose. N Engl J Med 348(24), 2471-2472.
-
(2003)
N Engl J Med
, vol.348
, Issue.24
, pp. 2471-2472
-
-
Yip, L.1
Dart, R.C.2
-
88
-
-
0033902642
-
Shorter duration of oral N-acetylcysteine therapy for acute acetaminophen overdose
-
OF Woo, RD Mueller, KR Olson, et al. (2000) Shorter duration of oral N-acetylcysteine therapy for acute acetaminophen overdose. Ann Emerg Med 35(4), 363-368.
-
(2000)
Ann Emerg Med
, vol.35
, Issue.4
, pp. 363-368
-
-
Woo, O.F.1
Mueller, R.D.2
Olson, K.R.3
-
89
-
-
0035146030
-
Risk factors in the development of adverse reactions to N-acetylcysteine in patients with paracetamol poisoning
-
LE Schmidt and K Dalhoff (2001) Risk factors in the development of adverse reactions to N-acetylcysteine in patients with paracetamol poisoning. Br J Clin Pharmacol 51(1), 87-91.
-
(2001)
Br J Clin Pharmacol
, vol.51
, Issue.1
, pp. 87-91
-
-
Schmidt, L.E.1
Dalhoff, K.2
-
90
-
-
0036850974
-
Fatal anaphylactoid reaction to N-acetylcysteine: caution in patients with asthma
-
AV Appelboam, PI Dargan and J Knighton (2002) Fatal anaphylactoid reaction to N-acetylcysteine: caution in patients with asthma. Emerg Med J 19(6), 594-595.
-
(2002)
Emerg Med J
, vol.19
, Issue.6
, pp. 594-595
-
-
Appelboam, A.V.1
Dargan, P.I.2
Knighton, J.3
-
91
-
-
0032916615
-
Delayed increase in acetaminophen concentration after Tylenol PM overdose
-
SY Ho, M Arellano and J Zolkowski-Wynne (1999) Delayed increase in acetaminophen concentration after Tylenol PM overdose. Am J Emerg Med 17(3), 315-317.
-
(1999)
Am J Emerg Med
, vol.17
, Issue.3
, pp. 315-317
-
-
Ho, S.Y.1
Arellano, M.2
Zolkowski-Wynne, J.3
-
92
-
-
0024262737
-
Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose. Analysis of the national multicenter study (1976 to 1985) [see comment]
-
MJ Smilkstein, GL Knapp, KW Kulig, et al. (1988) Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose. Analysis of the national multicenter study (1976 to 1985) [see comment]. N Engl J Med 319(24), 1557-1562.
-
(1988)
N Engl J Med
, vol.319
, Issue.24
, pp. 1557-1562
-
-
Smilkstein, M.J.1
Knapp, G.L.2
Kulig, K.W.3
-
93
-
-
0020600559
-
Paracetamol overdosage. Pharmacological considerations and clinical management
-
LF Prescott (1983) Paracetamol overdosage. Pharmacological considerations and clinical management. Drugs 25(3), 290-314.
-
(1983)
Drugs
, vol.25
, Issue.3
, pp. 290-314
-
-
Prescott, L.F.1
-
94
-
-
0025946778
-
Intravenous acetylcysteine in paracetamol induced fulminant hepatic failure: a prospective controlled trial
-
R Keays, PM Harrison, JA Wendon, et al. (1991) Intravenous acetylcysteine in paracetamol induced fulminant hepatic failure: a prospective controlled trial. BMJ 303(6809), 1026-1029.
-
(1991)
BMJ
, vol.303
, Issue.6809
, pp. 1026-1029
-
-
Keays, R.1
Harrison, P.M.2
Wendon, J.A.3
-
95
-
-
0026432652
-
Improvement by acetylcysteine of hemodynamics and oxygen transport in fulminant hepatic failure
-
PM Harrison, JA Wendon, AE Gimson, et al. (1991) Improvement by acetylcysteine of hemodynamics and oxygen transport in fulminant hepatic failure. N Engl J Med 324(26), 1852-1857.
-
(1991)
N Engl J Med
, vol.324
, Issue.26
, pp. 1852-1857
-
-
Harrison, P.M.1
Wendon, J.A.2
Gimson, A.E.3
-
96
-
-
0031026805
-
N-acetylcysteine improves indocyanine green extraction and oxygen transport during hepatic dysfunction [see comment]
-
J Devlin, AE Ellis, J McPeake, et al. (1997) N-acetylcysteine improves indocyanine green extraction and oxygen transport during hepatic dysfunction [see comment]. Crit Care Med 25(2), 236-242.
-
(1997)
Crit Care Med
, vol.25
, Issue.2
, pp. 236-242
-
-
Devlin, J.1
Ellis, A.E.2
McPeake, J.3
-
97
-
-
0027970408
-
Influence of N-acetylcysteine on indirect indicators of tissue oxygenation in septic shock patients: results from a prospective, randomized, double-blind study
-
CD Spies, K Reinhart, I Witt, et al. (1994) Influence of N-acetylcysteine on indirect indicators of tissue oxygenation in septic shock patients: results from a prospective, randomized, double-blind study. Crit Care Med 22(11), 1738-1746.
-
(1994)
Crit Care Med
, vol.22
, Issue.11
, pp. 1738-1746
-
-
Spies, C.D.1
Reinhart, K.2
Witt, I.3
-
98
-
-
0023552842
-
Potential use of cimetidine for treatment of acetaminophen overdose
-
KV Speeg (1987) Potential use of cimetidine for treatment of acetaminophen overdose. Pharmacotherapy 7(6 Pt 2 Suppl), 125-133.
-
(1987)
Pharmacotherapy
, vol.7
, Issue.6
, pp. 125-133
-
-
Speeg, K.V.1
-
99
-
-
0020623092
-
Is there a place for cimetidine or ethanol in the treatment of paracetamol poisoning?
-
JA Critchley, EH Dyson, AW Scott, et al. (1983) Is there a place for cimetidine or ethanol in the treatment of paracetamol poisoning? Lancet 1(8338), 1375-1376.
-
(1983)
Lancet
, vol.1
, Issue.8338
, pp. 1375-1376
-
-
Critchley, J.A.1
Dyson, E.H.2
Scott, A.W.3
-
100
-
-
0028354987
-
4-Methylpyrazole blocks acetaminophen hepatotoxicity in the rat
-
RJ Brennan, RF Mankes, R Lefevre, et al. (1994) 4-Methylpyrazole blocks acetaminophen hepatotoxicity in the rat. Ann Emerg Med 23(3), 487-494.
-
(1994)
Ann Emerg Med
, vol.23
, Issue.3
, pp. 487-494
-
-
Brennan, R.J.1
Mankes, R.F.2
Lefevre, R.3
-
101
-
-
0036299219
-
Reduction of toxic metabolite formation of acetaminophen
-
LV Eszter Hazai and K Monostory (2002) Reduction of toxic metabolite formation of acetaminophen. Biochem Biophys Res Commun 291(4), 1089-1094.
-
(2002)
Biochem Biophys Res Commun
, vol.291
, Issue.4
, pp. 1089-1094
-
-
Eszter Hazai, L.V.1
Monostory, K.2
-
102
-
-
17444450351
-
Experience with liver dialysis in acetaminophen induced fulminant hepatic failure: a preliminary report
-
M Akdogan, K El-Sahwi, U Ahmed, et al. (2003) Experience with liver dialysis in acetaminophen induced fulminant hepatic failure: a preliminary report. Turk J Gastroenterol 14(3), 164-167.
-
(2003)
Turk J Gastroenterol
, vol.14
, Issue.3
, pp. 164-167
-
-
Akdogan, M.1
El-Sahwi, K.2
Ahmed, U.3
|