Potentiation of methylmercury-induced death in rat cerebellar granular neurons occurs by further decrease of total intracellular GSH with BDNF via TrkB in vitro

Biological and Pharmaceutical Bulletin

Volumn 39, Issue 6, 2016, Pages 1047-1054

  Sakaue, Motoharu ^a   Maki, Takehiro ^b   Kaneko, Takuya ^a   Hemmi, Natsuko ^a   Sekiguchi, Hitomi ^a   Horio, Tomoyo ^a   Kadowaki, Erina ^a   Ozawa, Aisa ^c   Yamamoto, Masako ^a  

^a AZABU UNIVERSITY   (Japan)

^b Sleep Science Laboratories   (Japan)

^c PHARMACEUTICALS AND MEDICAL DEVICES AGENCY   (Japan)

Author keywords

Diethyl maleate; L buthionine sulfoximine; Methylmercury; Neuronal culture; Neurotrophin

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; BUTHIONINE SULFOXIMINE; GLUTATHIONE; MALEIC ACID DIETHYL ESTER; METHYLMERCURY; METHYLMERCURY DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL ASSAY; CELL LEVEL; CELL VIABILITY; CEREBELLAR GRANULAR NEURON; CONTROLLED STUDY; GLUTATHIONE CELL LEVEL; IN VITRO STUDY; MOLECULAR INTERACTION; NERVE CELL; NERVE CELL CULTURE; NERVE CELL NECROSIS; NEUROBLASTOMA CELL LINE; NONHUMAN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RAT; ANIMAL; CELL CULTURE; CELL DEATH; CELL SURVIVAL; CEREBELLUM; CYTOLOGY; DRUG EFFECTS; DRUG POTENTIATION; METABOLISM; TUMOR CELL LINE;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL DEATH; CELL LINE, TUMOR; CELL SURVIVAL; CELLS, CULTURED; CEREBELLUM; DRUG SYNERGISM; GLUTATHIONE; METHYLMERCURY COMPOUNDS; NEURONS; RATS; RECEPTOR, TRKB;

EID: 84971635984     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b16-00091     Document Type: Article

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